Francis Lynn 🇨🇦
@nictitate.bsky.social
530 followers 260 following 300 posts
dad, lab head, brewer, baker, beta cell maker https://lynnlab.com
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Reposted by Francis Lynn 🇨🇦
jmcelroy.bsky.social
My breaking file on the province requiring a referendum to kill Vancouver's Park Board.

Sim is avoiding criticism of the province on this decision — but he was originally hopeful to get rid of the park board in six months.

But he lost political capital, and the province wasn't inclined to help.
B.C. government says Vancouver requires a referendum to eliminate its park board | CBC News
The B.C. government has put forward legislation that would only allow the City of Vancouver to eliminate its independently elected parks board if it is approved by local voters in a referendum.
www.cbc.ca
Reposted by Francis Lynn 🇨🇦
gavinyamey.bsky.social
“A study, published on Wednesday in the New England Journal of Medicine, showed that last season’s 2024–2025 mRNA COVID vaccines reduced people’s risk of emergency department visits by 29%, their risk of hospitalizations by 39% & their risk of death by 64%”

Benefits were seen even if 0 risk factors
sorenlarsen.bsky.social
Annual COVID Vaccines Protect People against Severe Disease, Even with Prior Immunity

"The new research also “calls into question the idea that younger individuals and those without risk factors don’t need the vaccine,” Viswanathan says."
Annual COVID Vaccines Save Lives, New Study Shows
A new study shows that receiving an updated COVID vaccine reduced people’s risk of severe disease and death in all age groups, regardless of immunity from prior infection or vaccination
www.scientificamerican.com
nictitate.bsky.social
Congrats Scott, wow, what a year! Looking forward to reading
Reposted by Francis Lynn 🇨🇦
jmcelroy.bsky.social
In 2022, Ken Sim said line item budget comparisons were the cornerstone of his budget policy if he got elected mayor.

In 2025, he voted against it happening for a budget presentation with potentially $100 million in cuts because his newly appointed city manager told him no.
Reposted by Francis Lynn 🇨🇦
carlzimmer.com
Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE
nyti.ms
Reposted by Francis Lynn 🇨🇦
Reposted by Francis Lynn 🇨🇦
elisabethbik.bsky.social
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
Cartoon from the Nobel Assembly showing the three prize winners, their names, and “for their discoveries concerning peripheral immune tolerance.”
Reposted by Francis Lynn 🇨🇦
harmitmalik.bsky.social
I am leaving Rochester NY after attending the retirement fest of four giants in the field of evolutionary biology including my PhD advisor. This visit gave me a chance to revisit old haunts and reflect on my own somewhat unlikely origin story. 1/n
Reposted by Francis Lynn 🇨🇦
lukaszukab.bsky.social
Today, #ForeverCanadian brought 230,000 petition signatures to Edmonton. Our volunteers will continue collecting signatures until October 28. We need your signature to reach our 300,000 requirement to keep Alberta in Canada.

#ableg #Yeg #Yyc #CdnPoli
nictitate.bsky.social
The UPS tax. They are the worst.
adamrose.bsky.social
How bad are tariffs going?

I paid for $32 of shaving cream from Canada. Unique stuff I’ve used for years, nothing like it in US. Small family business.

UPS guy came to my door today with box and said I have to pay additional $120 before he can hand it to me.

That makes it 5x more expensive!!! 🤯
Screenshot of message from UPS:

Hi Adam,
All import fees must be paid prior to delivery.
Save time - prepay online for your FREIGHTCOM shipment. If import fees are not paid before delivery, an additional surcharge will be applied.
Total Amount Due
119.20 USD
Additional charges may have been applied based on recent tariff policy changes.
Pay Now ›
Reposted by Francis Lynn 🇨🇦
cirtn.bsky.social
🧵(5/7) Here are the publications from the 2nd half of Sept.2025
From Dr. Patrick MacDonald
"Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes” PMID: 41026524
www.jci.org/articles/vie...
JCI - Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes
www.jci.org
Reposted by Francis Lynn 🇨🇦
drugmonkey.bsky.social
yep. You can't make a 'better case' that convinces tyranny of the value of science since knowledge is tyranny's kryptonite.
sciencevs.bsky.social
This moment from our latest episode with science writer @edyong209.bsky.social is 🔥

We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪

Listen wherever, or watch on Spotify 👇

open.spotify.com/episode/7Evh...
nictitate.bsky.social
dukemedschool.bsky.social
A new study from Duke, led by Jonathan Campbell, PhD, reveals that pancreatic alpha cells do more than produce glucagon — they also generate GLP-1, a hormone that boosts insulin and regulates blood sugar.

🔗 Read more: https://medschool.duke.edu/news/alpha-cells-moonlight-secret-glp-1-factories
Two individuals, one in a lab coat and gloves, working together in a laboratory setting. Person standing by a window with arms crossed, reflecting on a glass surface next to them.
nictitate.bsky.social
Cool, congrats! Looking forward to checking this out
tobiasgreisle.bsky.social
Happy to share a new tool from the @heikolickert.bsky.social lab!
We generated human iPSC fluorescent reporter lines to monitor Wnt/PCP signaling activity by Flattop in stem cell derived β-cells.
doi.org/10.1016/j.sc...
Thanks to all the co-authors that helped in the present and the past!
Redirecting
doi.org
Reposted by Francis Lynn 🇨🇦
parismarx.com
I know I’ve been posting a lot about this, but it’s telling of how this government looks at society that at the very moment Mark Carney can’t stop talking about nation-building projects, he’s throwing the biggest nationwide service-delivery network on the scrap heap because it doesn’t make money.
Reposted by Francis Lynn 🇨🇦
Reposted by Francis Lynn 🇨🇦
ejrideout.bsky.social
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
Reposted by Francis Lynn 🇨🇦
jwoodgett.bsky.social
Oh Canada, don’t look this gift horse in the mouth. Highly skilled people have just been priced out of the US. Come north where the only taxes on your brain are the worlds most important scientific questions that you’ll help to answer.
gergely.pragmaticengineer.com
Those on an H1B cannot return to the US from tomorrow (Sunday) unless paying $100K. This is an out-of-the blue presidential action. We’ll see software engineers stranded abroad.

One easy to predict outcome: those on US visas will travel less… for work, for conferences etc.