The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

I am leaving Rochester NY after attending the retirement fest of four giants in the field of evolutionary biology including my PhD advisor. This visit gave me a chance to revisit old haunts and reflect on my own somewhat unlikely origin story. 1/n

California should probably just join Canada www.nytimes.com/2025/10/03/u...

Today, #ForeverCanadian brought 230,000 petition signatures to Edmonton. Our volunteers will continue collecting signatures until October 28. We need your signature to reach our 300,000 requirement to keep Alberta in Canada.

#ableg #Yeg #Yyc #CdnPoli

The UPS tax. They are the worst.

🧵(5/7) Here are the publications from the 2nd half of Sept.2025
From Dr. Patrick MacDonald
"Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes” PMID: 41026524
www.jci.org/articles/vie...

Congrats both!

yep. You can't make a 'better case' that convinces tyranny of the value of science since knowledge is tyranny's kryptonite.

Cool new research from the lab of Dr. Jacqueline Beaudry, PhD led by Sulayman Lyons looks at brown fat. I may not always fully understand this very foundational science, but I do understand the importance of doing this work. 🧪#ResearchMatters www.embopress.org/doi/full/10....

Cool, congrats! Looking forward to checking this out

I know I’ve been posting a lot about this, but it’s telling of how this government looks at society that at the very moment Mark Carney can’t stop talking about nation-building projects, he’s throwing the biggest nationwide service-delivery network on the scrap heap because it doesn’t make money.

The anti-tylenol lobby is winning! arstechnica.com/health/2025/...

A big study in JAMA last year in which 185 909 children were exposed to acetaminophen during pregnancy. Conclusion: Acetaminophen use during pregnancy was not associated with children's risk of autism, ADHD, or intellectual disability in sibling control analysis.

pubmed.ncbi.nlm.nih.gov/38592388/

I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.

Oh Canada, don’t look this gift horse in the mouth. Highly skilled people have just been priced out of the US. Come north where the only taxes on your brain are the worlds most important scientific questions that you’ll help to answer.

"Moderna liked Canada because it is a country where 'science is at the forefront.'"

I hope this remains the case @mark-carney.bsky.social

www.theglobeandmail.com/gift/2109fef...

Dear Rest of the World - please view this devastating situation as a major opportunity and argument to step up your investments - NOT as a signal to make your own cuts to research activities.

Save the date for the 2026 A-BC Islet Biology meeting! Looking forward to many fantastic presentations by trainees in islet biology from all over Canada as well as great keynote lectures. Please share widely! isletmeeting.weebly.com

A new #ClinicalTrials unit at Mount Saint Joseph Hospital in Vancouver will allow B.C. life sciences companies to test early-stage drugs locally.

It's the first facility in the province with the capacity to perform non-oncology Phase 1 clinical trials: https://bit.ly/4pzFQNu

In Canada, proposed cuts of 15% across the federal government would have a dramatic effect on already globally decimated research & science.

Join Canada's research & science community and tell PM Mark Carney to preserve the funding promised in 2024.

Send a letter: win.newmode.net/canadianasso...

Congratulations to Taylor Scheidl, the senior PhD student in the Thompson lab, on her new preprint 🎉 She showed that offspring born to obese dams are more likely to become obese due to more proliferation in early-life adipose progenitors, which leads to higher adipocyte numbers.

Not good: www.theglobeandmail.com/canada/artic...

I can see why folks in BC might applaud the brutal indecision of the NDP government when it comes to making tough financial decisions because it means fewer cuts in the short term.

But boy, lemme tell you, Budget 2029 is going to be freaking brutal.