Nature Reviews Endocrinology, Published online: 26 September 2025; doi:10.1038/s41574-025-01180-2Oestrogen is a key regulator in many metabolic processes, particularly in adipose tissue. This Review discusses the role of oestrogen in adipose tissue metabolism and its wider implications for systemic metabolic health.

Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...

Ohnishi et al. present the AVID mouse, which enables real-time, multiscale imaging of ATP dynamics in vivo across organs and cell types. This platform reveals spatially heterogeneous changes in energy metabolism during both physiological conditions and pathological states such as myocardial infarction, enabling systems-level analysis of metabolic regulation.

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Nature Metabolism, Published online: 19 August 2025; doi:10.1038/s42255-025-01342-6A series of fluorescent probes is designed that act as dual agonists on both GLP1 and GIP receptors, and are used to image receptor binding activities in tissues and animals.

An atlas study of adipose tissue in people with obesity undergoing weight loss and their lean counterparts reveals that weight loss reduces cell senescence but cannot reverse all the metabolic problem...

Nature Metabolism, Published online: 14 April 2025; doi:10.1038/s42255-025-01267-0The gut hormone tachykinin (Tk) is found to be regulated by protein intake in flies and mice. In flies, Tk is shown to impact food choices, sleep and lifespan.