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Marion Campbell

@marionkcampbell.bsky.social

950 followers 180 following 210 posts

Trialist; Methodologist; Statistician; Professor of Health Services Research; University of Aberdeen. Views my own. Hebridean. https://www.abdn.ac.uk/people/m.k.campbell

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Marion Kay Campbell is a Scottish medical statistician, clinical trialist, and academic administrator who is the dean of research for life sciences and medicine and a professor of health services research at the University of Aberdeen. .. more

Economics 26%

Mathematics 24%

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Marion Campbell @marionkcampbell.bsky.social · 3d

Taken today 😊

Marion Campbell @marionkcampbell.bsky.social · 4d

Lovely autumn colours on campus 🍂🍁 @uniofaberdeen.bsky.social

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Reposted by Marion Campbell

Richard Hooper @richardhooper.bsky.social · 9d

I'm doing a webinar in two weeks (15 Oct 1-2pm BST), part of NIHR Research Support Service's Methods Academy series, on the age-old question: should I do a stepped wedge trial?

Free registration, details here: tinyurl.com/z6cjvce3

@nihr-rss.bsky.social @wiphcem.bsky.social @qmul-wiph.bsky.social

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Reposted by Marion Campbell

Bristol Centre for Surgical Research @bristol-csr.bsky.social · 15d

Excellent three days in Bristol as part of the #BOASTiC (Bristol Oxford Aberdeen Surgical Trials Course). We've enjoyed the in-depth look at surgical trials with delegates designing their own studies by the end of the 3rd day! @marionkcampbell.bsky.social @situ-oxford.bsky.social

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Reposted by Marion Campbell

Marion Campbell @marionkcampbell.bsky.social · 18d

The measure can help highlight how an intervention may need to be improved ahead of full evaluation 7/7

Marion Campbell @marionkcampbell.bsky.social · 18d

Constructs include affective attitude (how someone feels about the intervention), burden, ethicality, intervention coherence (understanding of how the intervention works), opportunity costs, perceived effectiveness, & self-efficacy (one’s confidence that they can use it). 6/7

Marion Campbell @marionkcampbell.bsky.social · 18d

When assessing the acceptability of an intervention, Sekhon et al have developed a useful tool (the Theoretical Framework of Acceptability): a theory-based measure that can be used to assess acceptability of an intervention to its users. 5/7
bmchealthservres.biomedcentral.com/articles/10....

Development of a theory-informed questionnaire to assess the acceptability of healthcare interventions - BMC Health Services Research

Background The theoretical framework of acceptability (TFA) was developed in response to recommendations that acceptability should be assessed in the design, evaluation and implementation phases of he...

bmchealthservres.biomedcentral.com

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Marion Campbell @marionkcampbell.bsky.social · 18d

Assessment of acceptability can be explored through multiple approaches eg via qualitative interviews or focus groups, via questionnaires or via proxy measures eg consent rates 4/7

Marion Campbell @marionkcampbell.bsky.social · 18d

The MRC complex intervention framework gives a useful summary of the range of people whose views should be considered. It also encourages adopting a diverse approach. 3/7
See www.bmj.com/content/374/...

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Marion Campbell @marionkcampbell.bsky.social · 18d

This is particularly the case when planning for the evaluation of complex interventions as they are often multi-faceted and involve/impact many different parties (including at patient, professional and system levels) 2/7

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Marion Campbell @marionkcampbell.bsky.social · 18d

One of the key things to address when undertaking a feasibility study ahead of a trial is the acceptability of different aspects of the proposed trial (intervention, trial processes, proposed outcomes etc) to all relevant parties 1/7
#MethodologyMonday #125

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Reposted by Marion Campbell

Marion Campbell @marionkcampbell.bsky.social · 23d

This👇 …. often unseen but crucial role

UK CTU Network @ukcrc-ctu.org.uk · 23d

Statisticians are central to patient safety in clinical trials.

From designing stopping rules to monitoring adverse events, we ensure risks are detected early - protecting participants while maintaining trial integrity.

🔗 ukcrc-ctu.org.uk

#Statistics #UKCTUNetwork #WorldPatientSafetyDay2025

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Reposted by Marion Campbell

UK CTU Network @ukcrc-ctu.org.uk · 23d

Reposted by Graeme MacLennan, Marion Campbell

ICR-CTSU @icr-ctsu.bsky.social · 23d

We're currently looking for a Trials Methodologist/Senior Trials Methodologist to join our team.

You can find out more about the role and how to apply here:
jobs.icr.ac.uk/vacancies/13...

#ResearchJobs #TrialsMethodology🧪

Trials Methodologist/ Senior Trials Methodologist (Statistics) in Sutton | The Institute of Cancer Research

View details and apply for this Trials Methodologist/ Senior Trials Methodologist (Statistics) vacancy in Sutton. Salary : Commencement on the salary range is subject to comparable skills an...

jobs.icr.ac.uk

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Reposted by Marion Campbell

Raul Pacheco-Vega @raulpachecovega.bsky.social · 25d

“You can always edit a bad page. You can't edit a blank page.”
― Jodi Picoult

#WritingSky #AcademicSky

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Marion Campbell @marionkcampbell.bsky.social · 25d

📣FUNDING ALERT: The NIHR/MRC Better Methods Better Research Programme has three new calls open:
- Researcher-Led
- Methodology for the incorporation of health and environmental impacts in health/social care
- Guidance development

Closing 2nd Dec
See: www.nihr.ac.uk/funding-oppo...

Reposted by Marion Campbell

The Bone & Joint Journal @bonejointjournal.bsky.social · Sep 10

The use of Bayesian methods in the design of trials and the analysis of the findings provides several potential benefits, which may be particularly applicable in Trauma & Orthopaedic surgery.

#ClinicalTrials #BayesianStatistics #RCTs #OrthoSky
@docfarrow.bsky.social

ow.ly/xeXm50WRwZN

The Bone & Joint Journal.
Extract from article titled 'Clinical trials in Trauma and Orthopaedics: time to think Bayesian?'

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Reposted by Marion Campbell

Marion Campbell @marionkcampbell.bsky.social · Sep 8

A recent paper in the BMJ (by Ying et al) is a good read - with worked examples, tables and code to help calculate an appropriate pilot sample size. It also stresses the importance of aligning sample sizes with the objectives of the pilot study 6/6
www.bmj.com/content/bmj/...

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Marion Campbell @marionkcampbell.bsky.social · Sep 8

There are a number of papers outlining approaches to pilot study sample size calculations - from rules of thumb (eg Julious) to ones based on estimating precision of standard deviations eg Sim & Lewis 5/6
Julious: onlinelibrary.wiley.com/doi/10.1002/...
Sim & Lewis: www.jclinepi.com/article/S089...

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Marion Campbell @marionkcampbell.bsky.social · Sep 8

Totton et al published an interesting review exploring what sample sizes have been used in pilot and feasibility studies over recent years 4/6
pilotfeasibilitystudies.biomedcentral.com/articles/10....

A review of sample sizes for UK pilot and feasibility studies on the ISRCTN registry from 2013 to 2020 - Pilot and Feasibility Studies

Background Pilot and feasibility studies provide information to be used when planning a full trial. A sufficient sample size within the pilot/feasibility study is required so this information can be e...

pilotfeasibilitystudies.biomedcentral.com

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