Marion Campbell
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marionkcampbell.bsky.social
Marion Campbell
@marionkcampbell.bsky.social

Trialist; Methodologist; Statistician; Professor of Health Services Research; University of Aberdeen. Views my own. Hebridean.
https://www.abdn.ac.uk/people/m.k.campbell

Marion Kay Campbell is a Scottish medical statistician, clinical trialist, and academic administrator who is the dean of research for life sciences and medicine and a professor of health services research at the University of Aberdeen. .. more

Economics 26%
Mathematics 24%

Reposted by Marion Campbell

The 10 year follow-up results of the TOPKAT trial of total (TKR) vs partial (PKR) knee replacement are out! Similar clinical outcomes, but PKR more cost effective.
t.co/V4O7s6MvZe
https://www.sciencedirect.com/science/article/pii/S2665991325002504
t.co

Reposted by Marion Campbell

New fully funded PhD opportunity to come and work with me at the University of Glasgow exploring the role of data-driven interventions (audit and feedback) to improve environmental sustainability of the NHS. Deadline to apply: 12th Jan 2026.

Find out more here:
www.gla.ac.uk/colleges/mvl...

One of my 2026 goals is to be more present on BlueSky! Another is to recruit a great candidate to this 4-yr PhD studentship with us at the Aberdeen Centre for Evaluation -applying behavioural science to the design and delivery of clinical trials. Please share. www.findaphd.com/phds/project...
Improving health by improving trials – applying behavioural science to improve the design and delivery of clinical trials. at University of Aberdeen on FindAPhD.com
PhD Project - Improving health by improving trials – applying behavioural science to improve the design and delivery of clinical trials. at University of Aberdeen , listed on FindAPhD.com
www.findaphd.com

Reposted by Marion Campbell

Just 4 weeks to CCR Down Under 2025!

Join us to hear the results of 8 major critical care trials - in person or virtually

➡️ ImmunoSep
➡️ iRehab
➡️ CLIP II
➡️ ACTiVE
➡️ ARISE AFRICA
➡️ RSI
➡️ VITaCCA
➡️ ECMO REHAB

https://criticalcarereviews.com/meetings/ccr-down-under-2025

Reposted by Marion Campbell

Beginning Nov 1924, studies on the effect of lighting on worker productivity were performed at the Western Electric Hawthorn Plant. These were the basis for the concept of the Hawthorne Effect 1/2

Reposted by Marion Campbell

Reposted by Marion Campbell

The work provides accessible definitions of the core elements of an estimand which will help aid understanding and should ease the use of the estimand framework across the range of stakeholders 8/8

A new paper by @suziecro.bsky.social and colleagues will help in this regard. Working with public partners, they developed a practical tool to explain the attributes of an estimand in an accessible manner 7/8
trialsjournal.biomedcentral.com/articles/10....

However, the technical language around estimands makes it hard to discuss the concept with patients and public (and indeed with many researchers and clinicians). 6/8

Kahan et al provide a useful introduction to the estimand approach and to the different terms/approaches used: 5/8
www.bmj.com/content/384/...

We may want to know how effective the treatment was in all patients allocated to it (this is called a “treatment policy” estimand strategy); or only in those patients who received it as planned (called a “principal stratum” approach) or some other variation. 4/8

“Intercurrent events” are post-randomisation events (eg discontinuation of treatment or treatment switching) and the estimand describes precisely how these events will be handled in the analysis. 3/8

An #estimand is effectively a more precise specification of the research question(s) and how the treatment effect is to be estimated (hence estimand). It also specifically describes how so called “intercurrent events” will be handled in the analysis. 2/8

The term #estimand is now part of the technical language of trials - but it remains a concept that many find hard to understand. Recent work has aimed to make the term more accessible to researchers, patients & public 1/8
#MethodologyMonday #127

Reposted by Marion Campbell

In the EVERDAC trial involving patients with shock, results for death at day 28 indicated that management without early arterial catheter insertion was noninferior to early catheter insertion. Full trial results and Research Summary: nej.md/3LmOO0D

#MedSky #PulmSky

Reposted by Marion Campbell

The world’s largest and longest clinical trial in critical care, SuDDICU found a significant reduction in hospital-acquired infection in critically ill patients on mechanical ventilation, when given antibiotics preventatively before a new infection can develop.

Reposted by Marion Campbell

Reposted by Jeremy Grimshaw