Max Schelski
@maxschelski.bsky.social
3K followers 1.9K following 63 posts
Neuroscientist. Developing mathematical models of cell biology underlying synaptic plasticity. Coding Python. PhD done @ Bradke lab #NeuroDev #Microtubules PostDoc in Tchumatchenko group. #SynapticPlasticity #Dendrites https://github.com/maxschelski/
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maxschelski.bsky.social
Hi! I'm Max. I'm developing a #biophysical model of #microtubules in #neurons during #development. The model is based on my surprising experimental finding (lots of live-cell imaging) that the entire microtubule array in neurites flows retrogradely into the soma: www.science.org/doi/10.1126/... 🧪 🧠📈
Reposted by Max Schelski
tonykellyeu.bsky.social
Very happy our cautionary tale of GECI expression in the hippocampus is out in @eLife.
https://elifesciences.org/articles/93804
We describe Ca2+ waves though the hippocampus. Mesmerising but artefact of GECI expression.
Also a tweet print https://x.com/tonykellyEU/status/1723654794626154891. 1/3
Reposted by Max Schelski
tonykellyeu.bsky.social
Dendrites have been under the microscope, since 1888. We took it further and put dendrites under 3 different microscopes (ExM, STED, EM) and reconstructed entire branches to reveal fine nanoscale details. #SuperResolution #ElectronMicroscopy #Morphology
https://doi.org/10.1101/2025.07.18.664460
Reposted by Max Schelski
tonykellyeu.bsky.social
Recently I referred to how dendritic compartmentalisation increases computation.
What is a computational unit. How has the view evolved from point neuron (basis for ANNs). How a neuroscience view may increase AI efficiency.
buff.ly/zoF1rJz
preprint on compartmentalisation buff.ly/TAsJuVr
biological neuron is not same as point neuron
Reposted by Max Schelski
Reposted by Max Schelski
Reposted by Max Schelski
tpvogels.bsky.social
Here is your last reminder that the application deadline for Imbizo.Africa is nearing quickly, the 1st of July, in fact tomorrow. Still the place where diversity is at its best in the world! Tell all who need to hear. #africa #neuro
#Imbizo - Simons Computational Neuroscience Imbizo - #Imbizo
Simons Computational Neuroscience Imbizo summer school in Cape Town, South Africa
Imbizo.Africa
Reposted by Max Schelski
kendall-lough.bsky.social
First Bluesky post! I'm excited to share a preprint from my postdoctoral work where we 1) define the developmental mechanisms guiding formation of a vagal gut-brain circuit and 2) discover that this circuit regulates much more than just appetite. www.biorxiv.org/content/10.1...
Ontogeny of the vagal gut-brain axis
Gut-brain communication is a key component of homeostasis which regulates behaviors such as appetite and reward. Intestinal entero-endocrine cells (EECs) translate nutrient intake into signals which a...
www.biorxiv.org
Reposted by Max Schelski
k47h4.bsky.social
PhD/Postdoc position in Computational Neuroscience at the Institute of Neuroinformatics (UZH and ETH Zürich): we are investigating the neural circuits underlying perception and learning in uncertain environments: www.ini.uzh.ch/en/research/... #PhD #ComputationalNeuroscience #UZHZurich #ETHZurich
Open positions
www.ini.uzh.ch
Reposted by Max Schelski
laklab.bsky.social
Our work, out at Cell, shows that the brain’s dopamine signals teach each individual a unique learning trajectory. Collaborative experiment-theory effort, led by Sam Liebana in the lab. The first experiment my lab started just shy of 6y ago & v excited to see it out: www.cell.com/cell/fulltex...
Reposted by Max Schelski
hannahpayne.bsky.social
My latest Aronov lab paper is now published @Nature!

When a chickadee looks at a distant location, the same place cells activate as if it were actually there 👁️

The hippocampus encodes where the bird is looking, AND what it expects to see next -- enabling spatial reasoning from afar

bit.ly/3HvWSum
Reposted by Max Schelski
arnaghosh.bsky.social
Fantastic work on Multi-agent RL from
@dvnxmvlhdf5.bsky.social & @tyrellturing.bsky.social! 🤩
dvnxmvlhdf5.bsky.social
Preprint Alert 🚀

Multi-agent reinforcement learning (MARL) often assumes that agents know when other agents cooperate with them. But for humans, this isn’t always the case. For example, plains indigenous groups used to leave resources for others to use at effigies called Manitokan.
1/8
Manitokan are images set up where one can bring a gift or receive a gift. 1930s Rocky Boy Reservation, Montana, Montana State University photograph. Colourized with AI
Reposted by Max Schelski
erc.europa.eu
Planning to apply for #research #funding from the ERC?

From the next application rounds, expect changes to the:

• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)

More 👇 europa.eu/!RPHWvv
Changes to the 2026 and 2027 Work Programmes
With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...
europa.eu
Reposted by Max Schelski
manuelthery.bsky.social
the magic growing/shrinking GTP/GDP switch lies in the differential ability to bend out of plane and hold on neighbours.
Alone you go faster, together we go further.
Reposted by Max Schelski
christlet.bsky.social
New from the Baas lab: Regulation of axonal microtubule orientation by protein motors and TRIM46/augmin in hippocampal vs SCG neurons
faseb.onlinelibrary.wiley.com/doi/abs/10.1...
Reposted by Max Schelski
vbcscitraining.bsky.social
The @viennabiocenter.bsky.social PostDoc Program call is now open! We have 16 fully-funded positions for scientists with a PhD in biology, chemistry, physics, bioinformatics etc.

Apply here: training.vbc.ac.at/post-docs/vi...

#VBCPostDoc
Reposted by Max Schelski
roisinmcmanus.bsky.social
🥼 We’re looking for a #MSc student to work in our lab as part of their MSc thesis or internship on an interdisciplinary project @dzne.science, in Germany!

🧠 If you’re interested in #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad👇

jobs.dzne.de/en/jobs/1014...
Master student (f/m/x) in the field of Neuroimmunology 1447/2025/6
jobs.dzne.de
Reposted by Max Schelski
fzenke.bsky.social
1/6 Why does the brain maintain such precise excitatory-inhibitory balance?
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social
Reposted by Max Schelski
andrejpaleo.bsky.social
Big if true in nature:
"Strikingly, this phenomenon does not require additional mechanisms like intransitive or higher-order interactions; rather, coexistence arises from dense networks of indirect effects."
🧪 #EvoBio #Complexity #Macroecology
guimaguade.bsky.social
Microbial communities can harbor many species that do not coexist in pairs, yet can coexist in the full community. Here we provide the mathematical foundations of emergent coexistence, and explain why it can't be predicted from pairwise tests www.biorxiv.org/content/10.1...
Reposted by Max Schelski
benjulab.bsky.social
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
Reposted by Max Schelski
lisaschmors.bsky.social
🧠🤖 Computational Neuroscience summer school IMBIZO in Cape Town is open for applications again!
 
💻🧬 3 weeks of intense coursework & projects with support from expert tutors and faculty
 
📈Apply until July 1st!

🔗https://imbizo.africa/
Reposted by Max Schelski
takakikomiyama.bsky.social
Our paper is out in Nature.

By examining various inputs to the motor cortex during learning, we found that thalamic inputs learn to activate the cortical neurons encoding the movement being learned.

Tour de force by Assaf in collab with Felix and Marcus. Congrats!

www.nature.com/articles/s41...
Motor learning refines thalamic influence on motor cortex - Nature
Imaging and optogenetics in mice provide insight into the interplay between the primary motor cortex and the motor thalamus during learning, showing that thalamic inputs have a key role in the executi...
www.nature.com
Reposted by Max Schelski
monikakscholz.bsky.social
Science crew in Bonn and Cologne - please spread the word! Very happy to welcome @senguptalab.bsky.social to Bonn on May 13!
She's going to talk about salt sensing receptors in the pharynx, i.e. how do you make sure you don't overeat on salty snacks (if you're a worm).
mpinb.mpg.de/en/events/ev...
Neuroscience Seminar Series - MAX PLANCK INSTITUTE FOR NEUROBIOLOGY OF BEHAVIOR — CAESAR
mpinb.mpg.de
Reposted by Max Schelski
neuroprinciplist.bsky.social
Re-posting is appreciated: We have a fully funded PhD position in CMC lab @cmc-lab.bsky.social (at @tudresden_de). You can use forms.gle/qiAv5NZ871kv... to send your application and find more information. Deadline is April 30. Find more about CMC lab: cmclab.org and email me if you have questions.
forms.gle