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Reposted by MILO Lab
Reposted by MILO Lab
Roel Verhaak
@roelverhaak.bsky.social
· Jul 16
Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomas
Astrocytomas and oligodendrogliomas are slow-growing and treatment-sensitive IDH-mutant gliomas diagnosed at ages 30-50. Local tumor regrowth and treatment resistance is inevitable resulting in 3-10 y...
www.biorxiv.org
Reposted by MILO Lab
Yahaya Yabo
@yahayayabo.bsky.social
· Jul 5
Reposted by MILO Lab
Reposted by MILO Lab
Nature Neuroscience
@natneuro.nature.com
· May 20
A dynamic and multimodal framework to define microglial states - Nature Neuroscience
Sankowski and Prinz propose a classification framework for microglia states that considers the contextual plasticity of microglia. Their multimodal classification aligns a robust terminology with biol...
www.nature.com
Reposted by MILO Lab
Reposted by MILO Lab
Yahaya Yabo
@yahayayabo.bsky.social
· Apr 7
Reposted by MILO Lab
Reposted by MILO Lab
Ty Miller Lab
@tymillerlab.bsky.social
· Feb 27
Programs, origins and immunomodulatory functions of myeloid cells in glioma - Nature
A study of myeloid cells in gliomas, a type of brain tumour, used a factor-based computational framework to reveal four immunomodulatory gene-expression programs that are expressed across myeloid cell...
www.nature.com
Reposted by MILO Lab
MILO Lab
@milolab.bsky.social
· Jan 30
Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics - Nature Cancer
Ritter et al. present a spatial transcriptomics and deep learning-based approach named NePSTA (neuropathology spatial transcriptomic analysis) and leverage it to improve neuropathological diagnostics ...
www.nature.com
Reposted by MILO Lab
Reposted by MILO Lab