Syed Mian
@syedmian.bsky.social
350 followers
420 following
55 posts
Research fellow @crick.ac.uk #BonemarrowStemCells🩸
#MDS #Cancer
#DiseaseModelling #EnvironmentalMinglingMatters #CureForMDS
ASH-EHA TRTH2025
Opinions are my own!
https://scholar.google.com/citations?user=96tYyXUAAAAJ&hl=en
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Syed Mian
@syedmian.bsky.social
· Aug 23
Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo
Myeloproliferative Neoplasms (MPN) are malignancies of hematopoietic stem and progenitor cells (HSPCs) that lead to the overproduction of mature blood cells. These disorders include Essential Thrombo....
onlinelibrary.wiley.com
Reposted by Syed Mian
Reposted by Syed Mian
Syed Mian
@syedmian.bsky.social
· Jul 2
A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression - Nature Communications
In Myeloiddysplastic syndromes, CEBPA mutations are linked to disease progression and AML. Here, the authors use somatic reprogramming and genome editing to generate isogenic cell lines from an MDS pa...
www.nature.com
Reposted by Syed Mian
Reposted by Syed Mian
Reposted by Syed Mian
Reposted by Syed Mian
Reposted by Syed Mian
The Francis Crick Institute
@crick.ac.uk
· May 14
Marsupial research reveals how mammalian embryos form
Researchers at the Francis Crick Institute have revealed insight into why embryos erase a key epigenetic mark during early development, suggesting this may have evolved to help form a placenta.
www.crick.ac.uk
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