Alessio Bricca
@abricca.bsky.social
PhD in Health Sciences | Assistant Professor | #Exercise Physiologist | @MobilizeDk @FoF_research | @SyddanskUni | #physicalactivity #evidencesynthesis #RCT 🇮🇹🇩🇰🇪🇺
https://portal.findresearcher.sdu.dk/en/persons/abricca
https://portal.findresearcher.sdu.dk/en/persons/abricca
Pinned
Alessio Bricca
@abricca.bsky.social
· Jun 30
Exercise therapy and self-management support are more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity, without compromising safety. #multimorbidity
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
🌍 We tested whether a structured exercise and education program could improve HRQoL in people with multimorbidity.
✅ Key finding: Participants in the exercise program had better HRQoL at 12 months compared to usual care.
👉 Full study in @natmed.nature.com www.nature.com/articles/s41...
✅ Key finding: Participants in the exercise program had better HRQoL at 12 months compared to usual care.
👉 Full study in @natmed.nature.com www.nature.com/articles/s41...
Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial - Nature Medicine
The authors report findings from the MOBILIZE trial, which found that exercise therapy and self-management support improved patient-reported quality of life in individuals with multiple chronic condit...
www.nature.com
November 20, 2025 at 8:38 AM
🌍 We tested whether a structured exercise and education program could improve HRQoL in people with multimorbidity.
✅ Key finding: Participants in the exercise program had better HRQoL at 12 months compared to usual care.
👉 Full study in @natmed.nature.com www.nature.com/articles/s41...
✅ Key finding: Participants in the exercise program had better HRQoL at 12 months compared to usual care.
👉 Full study in @natmed.nature.com www.nature.com/articles/s41...
To dispel the misconception that exercise therapy wears down knee cartilage, clinicians should proactively address these concerns when treating patients with knee #osteoarthritis
open.spotify.com/episode/4JVh...
open.spotify.com/episode/4JVh...
Ep 232: Exercise therapy "wears down" my joint - myth or fact? With Dr Alessio Bricca
JOSPT Insights · Episode
open.spotify.com
July 28, 2025 at 11:24 AM
To dispel the misconception that exercise therapy wears down knee cartilage, clinicians should proactively address these concerns when treating patients with knee #osteoarthritis
open.spotify.com/episode/4JVh...
open.spotify.com/episode/4JVh...
Reposted by Alessio Bricca
Exercise therapy and self-management support are more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity, without compromising safety. #multimorbidity
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
June 30, 2025 at 10:22 AM
Exercise therapy and self-management support are more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity, without compromising safety. #multimorbidity
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
Managing #multimorbidity (two or more chronic health conditions) is one of the biggest challenges in healthcare today. It affects daily life, mental wellbeing, and overall functioning.
We have some good news www.nature.com/articles/s41...
We have some good news www.nature.com/articles/s41...
July 15, 2025 at 11:05 AM
Managing #multimorbidity (two or more chronic health conditions) is one of the biggest challenges in healthcare today. It affects daily life, mental wellbeing, and overall functioning.
We have some good news www.nature.com/articles/s41...
We have some good news www.nature.com/articles/s41...
The most effective #digital health interventions for promoting #physicalactivity in individuals with chronic conditions include #exercise combined with self-management, delivered via mixed technologies, or #web #app platforms.
pubmed.ncbi.nlm.nih.gov/40639802/
@ispah.org
pubmed.ncbi.nlm.nih.gov/40639802/
@ispah.org
Effect of Components and Delivery Modes of Digital Health Interventions Targeting Physical Activity in People With a Chronic Condition or Multimorbidity: A Systematic Review and Component Network Meta...
The most effective digital health interventions for promoting physical activity in individuals with chronic conditions include exercise combined with self-management, delivered via mixed technologies,...
pubmed.ncbi.nlm.nih.gov
July 15, 2025 at 7:34 AM
The most effective #digital health interventions for promoting #physicalactivity in individuals with chronic conditions include #exercise combined with self-management, delivered via mixed technologies, or #web #app platforms.
pubmed.ncbi.nlm.nih.gov/40639802/
@ispah.org
pubmed.ncbi.nlm.nih.gov/40639802/
@ispah.org
Even small increases in moderate-to-vigorous physical activity (MVPA) appear to be associated with low-grade inflammation in individuals with multimorbidity.
onlinelibrary.wiley.com/doi/10.1002/...
Secondary analysis of the #MOBILIZE trial published Nature Medicine lnkd.in/eHQ3kxUU
onlinelibrary.wiley.com/doi/10.1002/...
Secondary analysis of the #MOBILIZE trial published Nature Medicine lnkd.in/eHQ3kxUU
Device‐Based Physical Activity and Low‐Grade Inflammation in People With Multimorbidity: Cross‐Sectional Baseline Analysis From the MOBILIZE Trial
Physical activity (PA) has anti-inflammatory effects, but its impact on individuals with multimorbidity (two or more chronic conditions) is unclear. We examined the association between device-measure...
onlinelibrary.wiley.com
July 10, 2025 at 2:07 PM
Even small increases in moderate-to-vigorous physical activity (MVPA) appear to be associated with low-grade inflammation in individuals with multimorbidity.
onlinelibrary.wiley.com/doi/10.1002/...
Secondary analysis of the #MOBILIZE trial published Nature Medicine lnkd.in/eHQ3kxUU
onlinelibrary.wiley.com/doi/10.1002/...
Secondary analysis of the #MOBILIZE trial published Nature Medicine lnkd.in/eHQ3kxUU
Getting ready for #ECSS
I’ll be talking about exercise for people with multiple chronic conditions and its impact on inflammation, lipids, blood pressure, triglycerides, and cholesterol.
From a secondary analysis of the #MOBILIZE trial.
www.nature.com/articles/s41...
I’ll be talking about exercise for people with multiple chronic conditions and its impact on inflammation, lipids, blood pressure, triglycerides, and cholesterol.
From a secondary analysis of the #MOBILIZE trial.
www.nature.com/articles/s41...
July 3, 2025 at 11:55 AM
Getting ready for #ECSS
I’ll be talking about exercise for people with multiple chronic conditions and its impact on inflammation, lipids, blood pressure, triglycerides, and cholesterol.
From a secondary analysis of the #MOBILIZE trial.
www.nature.com/articles/s41...
I’ll be talking about exercise for people with multiple chronic conditions and its impact on inflammation, lipids, blood pressure, triglycerides, and cholesterol.
From a secondary analysis of the #MOBILIZE trial.
www.nature.com/articles/s41...
The Illusion of Simplicity in Therapeutic Exercise
Therapeutic exercise requires personalization, supervision, and continuous adaptation.
Read how we took this into account in our Nature Medicine paper www.nature.com/articles/s41...
Therapeutic exercise requires personalization, supervision, and continuous adaptation.
Read how we took this into account in our Nature Medicine paper www.nature.com/articles/s41...
Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial - Nature Medicine
The authors report findings from the MOBILIZE trial, which found that exercise therapy and self-management support improved patient-reported quality of life in individuals with multiple chronic condit...
www.nature.com
July 2, 2025 at 1:07 PM
The Illusion of Simplicity in Therapeutic Exercise
Therapeutic exercise requires personalization, supervision, and continuous adaptation.
Read how we took this into account in our Nature Medicine paper www.nature.com/articles/s41...
Therapeutic exercise requires personalization, supervision, and continuous adaptation.
Read how we took this into account in our Nature Medicine paper www.nature.com/articles/s41...
Reposted by Alessio Bricca
#Exercise continues to be the best medicine. A personalized exercise therapy and self-management support program is more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity @naturemedicine.bsky.social www.nature.com/articles/s41...
Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial - Nature Medicine
The authors report findings from the MOBILIZE trial, which found that exercise therapy and self-management support improved patient-reported quality of life in individuals with multiple chronic condit...
www.nature.com
June 30, 2025 at 11:10 AM
#Exercise continues to be the best medicine. A personalized exercise therapy and self-management support program is more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity @naturemedicine.bsky.social www.nature.com/articles/s41...
Reposted by Alessio Bricca
Dopo 12 mesi, chi ha seguito il programma (terapia fisica e supporto all'autogestione) ha riportato una qualità della vita relativa alla salute migliore rispetto a chi ha seguito solo le cure abituali, senza ⬆️ i rischi per la salute in persone affette da più patologie croniche. 1/2
July 1, 2025 at 7:43 AM
Dopo 12 mesi, chi ha seguito il programma (terapia fisica e supporto all'autogestione) ha riportato una qualità della vita relativa alla salute migliore rispetto a chi ha seguito solo le cure abituali, senza ⬆️ i rischi per la salute in persone affette da più patologie croniche. 1/2
Reposted by Alessio Bricca
New research from the MOBILIZE project, just published in Nature Medicine, shows that an exercise therapy + self-management program = better quality of life for people with multimorbidity.
www.nature.com/articles/s41...
#Science #Multimorbidity #Healthcare #NatureMedicine #MOBILIZE
www.nature.com/articles/s41...
#Science #Multimorbidity #Healthcare #NatureMedicine #MOBILIZE
Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial - Nature Medicine
The authors report findings from the MOBILIZE trial, which found that exercise therapy and self-management support improved patient-reported quality of life in individuals with multiple chronic condit...
www.nature.com
June 30, 2025 at 10:55 AM
New research from the MOBILIZE project, just published in Nature Medicine, shows that an exercise therapy + self-management program = better quality of life for people with multimorbidity.
www.nature.com/articles/s41...
#Science #Multimorbidity #Healthcare #NatureMedicine #MOBILIZE
www.nature.com/articles/s41...
#Science #Multimorbidity #Healthcare #NatureMedicine #MOBILIZE
Reposted by Alessio Bricca
Necessari ulteriori studi di conferma per indagare anche la rilevanza clinica di tale differenza tra i gruppi. Ottimo lavoro @abricca.bsky.social e considerate caldamente l'esercizio fisico come uno dei "farmaci" più potenti per la nostra salute: un investimento per il futuro! 2/2 💪🏼🔥
July 1, 2025 at 7:43 AM
Necessari ulteriori studi di conferma per indagare anche la rilevanza clinica di tale differenza tra i gruppi. Ottimo lavoro @abricca.bsky.social e considerate caldamente l'esercizio fisico come uno dei "farmaci" più potenti per la nostra salute: un investimento per il futuro! 2/2 💪🏼🔥
Grazie @mattscie.bsky.social per contribuire a diffondere questo messaggio!
Il nostro trial #MOBILIZE è il primo che dimostra che si può migliorare la qualità di vita in questi pazienti 🤞
La strada è ancora lunga ma la direzione è giusta!✅
www.nature.com/articles/s41...
Il nostro trial #MOBILIZE è il primo che dimostra che si può migliorare la qualità di vita in questi pazienti 🤞
La strada è ancora lunga ma la direzione è giusta!✅
www.nature.com/articles/s41...
July 1, 2025 at 7:50 AM
Grazie @mattscie.bsky.social per contribuire a diffondere questo messaggio!
Il nostro trial #MOBILIZE è il primo che dimostra che si può migliorare la qualità di vita in questi pazienti 🤞
La strada è ancora lunga ma la direzione è giusta!✅
www.nature.com/articles/s41...
Il nostro trial #MOBILIZE è il primo che dimostra che si può migliorare la qualità di vita in questi pazienti 🤞
La strada è ancora lunga ma la direzione è giusta!✅
www.nature.com/articles/s41...
Reposted by Alessio Bricca
Exercise therapy - still too underrepresented in many countries and in health providers catalogues…
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial - Nature Medicine
The authors report findings from the MOBILIZE trial, which found that exercise therapy and self-management support improved patient-reported quality of life in individuals with multiple chronic condit...
www.nature.com
June 30, 2025 at 8:34 PM
Exercise therapy - still too underrepresented in many countries and in health providers catalogues…
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Exercise therapy and self-management support are more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity, without compromising safety. #multimorbidity
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
June 30, 2025 at 10:22 AM
Exercise therapy and self-management support are more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity, without compromising safety. #multimorbidity
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
Reposted by Alessio Bricca
L'esercizio fisico ha un potente effetto antinfiammatorio, aumenta la stabilità del genoma, riduce la senescenza e migliora le funzioni cognitive e l'immunità. Tutti benefici che rendono l'esercizio fisico il "farmaco" più potente disponibile. Ed è gratis! 🧪
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Systematic profiling reveals betaine as an exercise mimetic for geroprotection
Elucidating the multi-faceted health effects of exercise in humans identifies kidney-derived
betaine as an exercise mimetic acting as a TBK1 inhibitor with anti-inflammatory and
geroprotective activit...
www.cell.com
June 29, 2025 at 7:19 AM
L'esercizio fisico ha un potente effetto antinfiammatorio, aumenta la stabilità del genoma, riduce la senescenza e migliora le funzioni cognitive e l'immunità. Tutti benefici che rendono l'esercizio fisico il "farmaco" più potente disponibile. Ed è gratis! 🧪
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Thanks for helping to spread such important message 🙏
Exercise Therapy ‘Wears Down’ My Knee Joint: Myth or Reality?
pubmed.ncbi.nlm.nih.gov/40536442/
To dispel the misconception that exercise therapy wears down knee cartilage, clinicians should proactively address these concerns when treating patients with knee osteoarthritis.
pubmed.ncbi.nlm.nih.gov/40536442/
To dispel the misconception that exercise therapy wears down knee cartilage, clinicians should proactively address these concerns when treating patients with knee osteoarthritis.
June 26, 2025 at 5:22 AM
Thanks for helping to spread such important message 🙏
Reposted by Alessio Bricca
More often than you might think, I hear on the street, on TV, and read in newspapers that people with osteoarthritis should refrain from exercise therapy due to the 'damage' it may cause to the cartilage.
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
June 22, 2025 at 7:37 PM
More often than you might think, I hear on the street, on TV, and read in newspapers that people with osteoarthritis should refrain from exercise therapy due to the 'damage' it may cause to the cartilage.
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
June 24, 2025 at 4:46 AM
More often than you might think, I hear on the street, on TV, and read in newspapers that people with osteoarthritis should refrain from exercise therapy due to the 'damage' it may cause to the cartilage.
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
June 22, 2025 at 7:37 PM
More often than you might think, I hear on the street, on TV, and read in newspapers that people with osteoarthritis should refrain from exercise therapy due to the 'damage' it may cause to the cartilage.
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
It does not really seem to be the case 👇
www.jospt.org/doi/10.2519/...
In adults with at least one chronic disease, anti-inflammatory diets lead to small improvements in physical component HRQOL, which may not be clinically relevant. No effect was found on the mental component or general HRQOL. Further high-quality RCTs may change this conclusion.
June 11, 2025 at 11:47 AM
In adults with at least one chronic disease, anti-inflammatory diets lead to small improvements in physical component HRQOL, which may not be clinically relevant. No effect was found on the mental component or general HRQOL. Further high-quality RCTs may change this conclusion.
In 2021 we found that exercise therapy may be a promising solution also for patients with multiple chronic conditions.
After a few years of work, we now know so much more about it and can’t wait to share the whole story.
For now have a look at this systematic review 👇
After a few years of work, we now know so much more about it and can’t wait to share the whole story.
For now have a look at this systematic review 👇
June 10, 2025 at 7:25 PM
In 2021 we found that exercise therapy may be a promising solution also for patients with multiple chronic conditions.
After a few years of work, we now know so much more about it and can’t wait to share the whole story.
For now have a look at this systematic review 👇
After a few years of work, we now know so much more about it and can’t wait to share the whole story.
For now have a look at this systematic review 👇
Exercises reduces the risk of colon cancer recurrence 👇 @natmed.nature.com @nejm.org
June 10, 2025 at 7:15 PM
Exercises reduces the risk of colon cancer recurrence 👇 @natmed.nature.com @nejm.org
Structured #Exercise after Adjuvant #Chemotherapy for Colon #Cancer
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
@nejm.org
June 5, 2025 at 2:14 PM
Structured #Exercise after Adjuvant #Chemotherapy for Colon #Cancer
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
@nejm.org
Throwback from my talk at the Danish Society for Cardiopulmonary Physiotherapy 👇
#exercise #physicalactivity #chronicconditions #multimorbidity #research
#exercise #physicalactivity #chronicconditions #multimorbidity #research
May 31, 2025 at 5:26 AM
Throwback from my talk at the Danish Society for Cardiopulmonary Physiotherapy 👇
#exercise #physicalactivity #chronicconditions #multimorbidity #research
#exercise #physicalactivity #chronicconditions #multimorbidity #research