In the last decade, post-extubation non-invasive respiratory support has nearly doubled with an approximately 10 percent re-intubation risk reduction. High-risk groups may benefit, but overuse may exi...

Background: Pediatric critical asthma is one of the most frequent reasons for presentation to the emergency department and admission to the floor or pediatric ICU (PICU) in pediatric patients. Clinica...

Mechanical ventilation strategies that balance lung and diaphragm protection have not been extensively tested in clinical trials. We conducted a single-center, phase II randomized controlled trial ...

To address the lack of guidance for clinicians in their care of children with critical asthma, a multidisciplinary team of medical providers used Grading of Recommendations, Assessment, Development, a...

Despite being the most common chronic lung disease in children, asthma continues to be frequently misdiagnosed in the pediatric population. The recommendations to establish a diagnosis of asthma in sc...

Infants and children frequently require mechanical ventilation. Daily extubation readiness testing is currently recommended to minimize time on mechanical ventilation, which is associated with the dev...

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Invasive mechanical ventilation (MV) is one of the most practiced interventions in the intensive care unit (ICU) and is unmistakably lifesaving for children with acute respiratory failure (ARF). Howev...

Timing of tracheostomy was variable, and duration of MV was longer than previously reported. The large variability in patients requiring MV and the associated health-care burden and outcomes across PICUs suggest that further investigation of the factors influencing the care of children with MV is warranted.

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