Adrian Woolfson
@adrianwoolfson.bsky.social
Opinions @WSJ.com & @Science.org. Author Life Without Genes @harpercollins.bsky.social & On The Future of Species bloomsburybooksuk.bsky.social (12 Feb 2026) & @MITpress.bsky.social (17 Mar, 2026). www.adrianwoolfson.com. Founder Genyro.com
Reposted by Adrian Woolfson
Terrific new paper by @jessicalwarelab.bsky.social and others on dragonfly wings, in particular the hydrocarbons which act in multiple ways - structurally, pheromonally and in terms of water resistance. Wish I were still teaching, I'd use this as a great example. of multiple adaptations.
The secrets of the extreme durability of odonata wings
Abstract. Essential properties considered in the design, fabrication, and application of contemporary bio/nanomaterials have been modeled on adaptations of
academic.oup.com
November 24, 2025 at 5:45 PM
Terrific new paper by @jessicalwarelab.bsky.social and others on dragonfly wings, in particular the hydrocarbons which act in multiple ways - structurally, pheromonally and in terms of water resistance. Wish I were still teaching, I'd use this as a great example. of multiple adaptations.
Yikes. Not a good time in history to be a radiologist. Looks like AI has outperformed humans in the radiological (CT) diagnosis of pancreatic cancer.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Artificial intelligence and radiologists in pancreatic cancer detection using standard of care CT scans (PANORAMA): an international, paired, non-inferiority, confirmatory, observational study
Pancreatic ductal adenocarcinoma (PDAC) has the worst prognosis among major cancer types, primarily due to late diagnosis on contrast-enhanced CT. Art…
www.sciencedirect.com
November 24, 2025 at 12:20 PM
Yikes. Not a good time in history to be a radiologist. Looks like AI has outperformed humans in the radiological (CT) diagnosis of pancreatic cancer.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
You really absolutely have to read this paper, if you haven’t already. It’s one of the most important ones I have read for a while. Paradigm changing. Big congrats to the Brian Hie team! Super exciting. Important things ahead.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Semantic design of functional de novo genes from a genomic language model - Nature
By learning a semantics of gene function based on genomic context, the genomic language model Evo autocompletes DNA prompts to generate novel genes encoding protein and RNA molecules with defined acti...
www.nature.com
November 23, 2025 at 9:41 PM
You really absolutely have to read this paper, if you haven’t already. It’s one of the most important ones I have read for a while. Paradigm changing. Big congrats to the Brian Hie team! Super exciting. Important things ahead.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Therapeutic genome editing using PERT (prime editing-mediated readthrough of premature termination codons). Edits tRNA to rescue nonsense mutations in a disease-agnostic manner by allowing read-through of premature termination codons and with a very low off-target.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Prime editing-installed suppressor tRNAs for disease-agnostic genome editing - Nature
A new strategy that uses prime editing to convert an endogenous tRNA into a suppressor tRNA shows therapeutic potential for multiple genetic diseases that are caused by premature stop codons.
www.nature.com
November 22, 2025 at 10:00 AM
Therapeutic genome editing using PERT (prime editing-mediated readthrough of premature termination codons). Edits tRNA to rescue nonsense mutations in a disease-agnostic manner by allowing read-through of premature termination codons and with a very low off-target.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
How do living things shape the materials around them? The Tom Ellis lab is set to find out.
www.imperial.ac.uk/news/article...
www.imperial.ac.uk/news/article...
€10m research grant to underpin sculptable tissues
Professor Tom Ellis has been awarded a €3.3 million share of a prestigious European Research Council (ERC) Synergy Grant.
www.imperial.ac.uk
November 21, 2025 at 4:08 PM
How do living things shape the materials around them? The Tom Ellis lab is set to find out.
www.imperial.ac.uk/news/article...
www.imperial.ac.uk/news/article...
BioEmu: Sampling the conformational landscapes of proteins 10,000 faster.
share.google/iRfcbOvXzZew...
share.google/iRfcbOvXzZew...
Scalable emulation of protein equilibrium ensembles with generative deep learning
Following the sequence and structure revolutions, predicting functionally relevant protein structure changes at scale remains an outstanding challenge. We introduce BioEmu, a deep learning system that...
share.google
November 20, 2025 at 1:08 PM
BioEmu: Sampling the conformational landscapes of proteins 10,000 faster.
share.google/iRfcbOvXzZew...
share.google/iRfcbOvXzZew...
Brian Hie does it again! Evo can use surrounding genomic context to generate novel functional genes through an emergent approach called ‘semantic design’
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Semantic design of functional de novo genes from a genomic language model - Nature
By learning a semantics of gene function based on genomic context, the genomic language model Evo autocompletes DNA prompts to generate novel genes encoding protein and RNA molecules with defined acti...
www.nature.com
November 19, 2025 at 9:37 PM
Brian Hie does it again! Evo can use surrounding genomic context to generate novel functional genes through an emergent approach called ‘semantic design’
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Microscopic programmable ‘flowers’ made from DNA. Autonomous behavior at microscale.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reversible metamorphosis of hierarchical DNA–inorganic crystals - Nature Nanotechnology
Actuators based on DNA–inorganic hybrid crystals reversibly change shape, which can be programmed by the length and composition of the DNA polymer, and induce cascaded reactions of compartmentalized e...
www.nature.com
November 18, 2025 at 2:42 AM
Microscopic programmable ‘flowers’ made from DNA. Autonomous behavior at microscale.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An artificial flower design toolkit
November 17, 2025 at 11:32 AM
An artificial flower design toolkit
