Interested in how T cells are regulated in a tissue-specific manner? Karthik Varanasi’s exciting work shows Bile Acid synthesis impedes tumor-specific T cell responses during liver cancer @science.org Huge THANKS to all the amazing collaborators + @salkinstitute, SBP
www.science.org/doi/10.1126/...

The new CRISPR-StAR tool by @ulielling.bsky.social and team provides elegant new opportunities for in vivo screens. Glad we @aelewaut.bsky.social could contribute a bit.

Thrilled to share that our paper www.nature.com/articles/s41... is featured in a fantastic Nature News & Views piece by thomastueting.bsky.social! 🎉 Grateful for the spotlight on our research and its impact on understanding cancer immunology. www.nature.com/articles/d41... 👀👉 rdcu.be/d3cRz

🧪Cross-Dressing intratumoral monocytes fulfill the job of cDC1s in supporting tumor-infiltrating CD8 T cells in their anti-cancer functions. Great to have contributed some 🔬&🧫 to this tour de force study by @obenaufa.bsky.social

Cancer cells blunt monocyte IFN while increasing PGE2 to inhibit T cell immunity @obenaufa.bsky.social @aelewaut.bsky.social @guillemxtivill.bsky.social
www.nature.com/articles/s41...

Extremely excited to see my PhD work in the @obenaufa.bsky.social published today in @natureportfolio.bsky.social 🤩. A big thank you to everyone who contributed, special thank you to my partner in crime @guillemxtivill.bsky.social - it was a lot of fun to work on this together! 🥳

#Immunotherapy has transformed #cancer treatment, but some cancers evade immune defenses, causing resistance.

@obenaufa.bsky.social's lab has discovered how inflammatory monocytes—a type of immune cell—can reactivate cancer-killing T cells within tumors.

Read more: imp.ac.at/news/article...

Super talk at #EMDS2024 by Anna Obenauf on myeloid cell hubs for T cell interactions in cancer 👏

And this is coming out in Nature 🧪 in just a few hours - congrats to Anais, Guillem, Anna & all authors 🥳🎉

@aelewaut.bsky.social
@guillemxtivill.bsky.social
@obenaufa.bsky.social
@impvienna.bsky.social

Dendritic cells maintain the CAR T cell pool in irradiated tumors
www.biorxiv.org/content/10.1...