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Reposted by Alba Silipo
Alba Silipo
@albasilipo.bsky.social
· Apr 26
Insights into Siglec‐7 Binding to Gangliosides: NMR Protein Assignment and the Impact of Ligand Flexibility
The molecular recognition of the sugar moiety of GD3 and Gb3 (globotriaosylceramide) derivatives by Siglec-7 has been thoroughly studied offering insights for cancer diagnostics and therapies. A comb....
advanced.onlinelibrary.wiley.com
Alba Silipo
@albasilipo.bsky.social
· Apr 10
Insights into stability, dimerisation, and ligand binding properties of Siglec-7: Isotope labelling in HEK293 cells for protein characterisation by NMR spectroscopy
Siglec-7, an immune checkpoint receptor, has emerged as a promising target for cancer immunotherapy due to its involvement in the regulation of immune…
www.sciencedirect.com
Reposted by Alba Silipo
Reposted by Alba Silipo
Reposted by Alba Silipo
Reposted by Alba Silipo