Roberta
@robertamarchetti.bsky.social
17 followers
10 following
2 posts
AssociateProfessor@OrganicChemistry@University of Naples Federico II. Protein-Glycoconjugate Interaction Studies by NMR. Coordinator of MSCA-DN #AUREUS. PI of ERC project #GLYCOSWITCH.
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Roberta
@robertamarchetti.bsky.social
· May 6
Reposted by Roberta
Alba Silipo
@albasilipo.bsky.social
· Apr 26
Insights into Siglec‐7 Binding to Gangliosides: NMR Protein Assignment and the Impact of Ligand Flexibility
The molecular recognition of the sugar moiety of GD3 and Gb3 (globotriaosylceramide) derivatives by Siglec-7 has been thoroughly studied offering insights for cancer diagnostics and therapies. A comb....
advanced.onlinelibrary.wiley.com
Reposted by Roberta
Alba Silipo
@albasilipo.bsky.social
· Apr 10
Insights into stability, dimerisation, and ligand binding properties of Siglec-7: Isotope labelling in HEK293 cells for protein characterisation by NMR spectroscopy
Siglec-7, an immune checkpoint receptor, has emerged as a promising target for cancer immunotherapy due to its involvement in the regulation of immune…
www.sciencedirect.com