New dementia data hub shared by Melinda Power at #MELODEM2025

This resource uses Medicare claims and encounter data to report and map diagnosed incidence and prevalence of dementia

www.dementiadatahub.org

Individual participant data from more trials is needed to help inform optimal trial design

Excellent talk at #MELODEM2025 by @sfackley.bsky.social evaluating amyloid as a surrogate marker with individual level A4 trial data

One big take away — 5 years was not enough time to see cognitive decline in the placebo group == a major challenge

Curious about conducting mechanism-driven interventions? CLIMBR is a great tool to support investigators in determining how to test mechanisms, learn more on May 22 !! Details below!!

Register: z.umm.edu/CLIMBRwebinar

Dr. Ambar Kulshreshtha is the lead author of a JAMA Network Open study examining undiagnosed cognitive impairment at federally qualified health centers. The study found that 75% of participants had undiagnosed cognitive issues. #dementia #FamilyMedicine #PrimaryCare #SDoH #ADRD #MedSky #PublicHealth

Sharing for visibility www.statnews.com/2025/03/03/n...

Thank you @statnews.com

I’m so very sorry. RISE is a tremendous effort and is greatly needed. We value you and your science.

This is both ethically distressing and scientifically flawed reasoning for discontinuing needed research to ensure ALL humans are in our science.

Alzheimer’s disease does not discriminate and good science includes ALL. Gratitude to @jaceflatt.bsky.social and colleagues for your leadership.

Of the 4000 researchers at NIH, only 20% are tenured. They’re going to fire all the rest as their contracts come up for renewal, absolutely decimating research at the NIH. This is catastrophic, not just for Americans, but for the whole world.

www.science.org/content/arti...

"VA researchers whose contracts are about to expire . . . will not be renewed, even when funding [through extramural grants is] in place to pay them. Should the VA continue this policy . . . over the months to come, the entire VA research workforce could be decimated."

Facts: Representatives Tim Burchett (R-TN) and Victoria Spartz (R-IN) voted to gut #Medicaid while nearly 1 in 5 of Burchett's constituents and 1 in 4 of Spartz's rely on Medicaid for their healthcare....

First post!!

New reading material:

We explore minimal clinically important differences for function in AD/ADRD trials + consider opportunities to improve outcome measure sensitivity and attention to the priorities of those living with dementia

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

“This is a blatant attempt to gut the universities and health research that have saved so many lives and given economic opportunity to so many people.” @iwashyna.bsky.social on impact of new NIh order to cut research indirect costs. www.statnews.com/2025/02/07/n...

Scientists and journalists need to figure out right quick how to explain to the average person how a massive change in research indirects will impact the medical care they and their children get (eg at the local children’s hospital), the education their children will get, the price of tuition, etc.

The new NIH policy for indirect costs going forward is capped at 15%.

This is forever going to alter the science ecosystem, upending and destroying a number of programs at universities across the country.

grants.nih.gov/grants/guide...

ATTENTION

If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at [email protected].

I will keep all information confidential.

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