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UK CTU Network @ukcrc-ctu.org.uk · 2d

Great to have so many engaged people in the room!

More workshops are planned for 2026.

Follow us here and on LinkedIn find out about future training opportunities.

www.linkedin.com/company/ukcrc-registered-ctu-network/

#UKCTUNetwork #HTBAGCI #ClinicalTrials

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Richard Hooper @richardhooper.bsky.social · 11d

I'm doing a webinar in two weeks (15 Oct 1-2pm BST), part of NIHR Research Support Service's Methods Academy series, on the age-old question: should I do a stepped wedge trial?

Free registration, details here: tinyurl.com/z6cjvce3

@nihr-rss.bsky.social @wiphcem.bsky.social @qmul-wiph.bsky.social

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Marion Campbell @marionkcampbell.bsky.social · Nov 25

Many of you know I post something about methods most Mondays on the “other side”… will share here too.
Here is today’s …
It is often important to assess not only the effectiveness of an interventions in a trial but also the #CostEffectiveness of the intervention 1/7
#MethodologyMonday #106

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CTRU Complex Interventions @complexleedsctru.bsky.social · Jan 22

There's only 2 days left to sign up for our Masterclass in the Design and Conduct of Complex Intervention Evaluations!

Limited spaces are left! Register here - t.co/V6Q7p51feu

Prof Amanda J Farrin @amandafarrin.bsky.social · Jan 9

We're running our annual online Masterclass in Complex Interventions Evaluations over 3 days in January and February.

Come and learn from our expert team of complex interventions trialists at @leedsctru.bsky.social

Register now to reserve your place. Deadline 24 Jan.
Link below 👇

FReSH START @freshstart-uk.bsky.social · Jan 13

FReSH START is a research project aiming to develop a therapy intervention for adults who self-harm. We are now running a clinical trial to see if the therapy we developed is effective and if it improves people's quality of life. #introduction #mentalhealthresearch #selfharm #NIHR

PenARC (NIHR ARC South West Peninsula) @penarc.bsky.social · Feb 13

PenARC & @arc-yharc.bsky.social researchers are working in partnership with older people with #heartfailure and #frailty to increase their independence.

> Learn more: tinyurl.com/4xt8f7en

@nihrarcs.bsky.social @exeter.ac.uk @universityofleeds.bsky.social @livunipress.bsky.social @nihr.bsky.social

NIHR APPLIED RESEARCH COLLABORATION SOUTH WEST PENINSULA.
Two older men smile as they walk through a park.

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Marion Campbell @marionkcampbell.bsky.social · Jun 16

At #CCR25, we saw some trials use a #CompositeOutcome (an endpoint that combines more than one outcome into a single measure) & also saw some of the problems these can throw up. I have discussed these before but thought it would be useful to revisit 1/9
#MethodologyMonday #120

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Sarah Alderson @imp-sci-saraha.bsky.social · Jun 6

Fern Harvey’s fab poster presentation of her systematic review on process evaluations for complex intervention trials. Better reporting of context, mechanisms of action and fidelity would enable greater learning about successful interventions #ImpSci #EIE2025 @au-primarycareuol.bsky.social

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Marion Campbell @marionkcampbell.bsky.social · Jun 2

A cluster randomised crossover design incorporates the principles of both cluster trials (where groups of individuals eg wards, schools etc are randomly assigned) and crossover trials where, in this case, the clusters cross over to different treatment/s for set time periods 2/7

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UK CTU Network @ukcrc-ctu.org.uk · Mar 20

🚀 Exciting News! 🚀

Interested in or leading a clinical trial?

Want to be the best Chief Investigator you can be?

This updated course is for you!

tinyurl.com/HTBAGCI

#ClinicalTrials #CITraining

@leedsctru.bsky.social @amandafarrin.bsky.social

Flyer advertising a training course on How to be a great chief investigator for clinical trials. Find out more via the following link https://tinyurl.com/HTBAGCI

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Prof Amanda J Farrin @amandafarrin.bsky.social · Mar 12

Phew: ResearchFish submitted again for another year ✅️

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Marion Campbell @marionkcampbell.bsky.social · Mar 10

A common issue in trials is how to accommodate multiple important outcomes. Approaches include composite outcomes or using the win ratio method (I have posted on these before). A newer method is the #DOOR (Desirability of Outcome Ranking) approach 1/7
#MethodologyMonday #113

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Prof Amanda J Farrin @amandafarrin.bsky.social · Feb 13

📢 Delighted our CHART trial is now OPEN to recruitment

Massive effort from our @complexleedsctru.bsky.social trial team, @drandyclegg.bsky.social @vickigphysio.bsky.social & many others to get this complex study ready to go 🎉

🙏 @nihr.bsky.social for funding

PenARC (NIHR ARC South West Peninsula) @penarc.bsky.social · Feb 13

PenARC & @arc-yharc.bsky.social researchers are working in partnership with older people with #heartfailure and #frailty to increase their independence.

> Learn more: tinyurl.com/4xt8f7en

@nihrarcs.bsky.social @exeter.ac.uk @universityofleeds.bsky.social @livunipress.bsky.social @nihr.bsky.social

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Katie Gillies @katiegillies.bsky.social · Feb 12

Currently low response rates from CTU Directors (n=5), Programmers/Data Managers (n=0), & QA Managers (n=3) working in clinical trials. We need to know what these groups think the challenges are for greener trials.

forms.office.com/e/fkeLD8HbMA

Please complete &RT

@ukctunetwork.bsky.social

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Prof Amanda J Farrin @amandafarrin.bsky.social · Feb 3

Follow @freshstart-uk.bsky.social for all updates from our @leedsctru.bsky.social @nihr.bsky.social programme grant. We've just moved over to this platform 🙂

FReSH START @freshstart-uk.bsky.social · Jan 13

FReSH START is a research project aiming to develop a therapy intervention for adults who self-harm. We are now running a clinical trial to see if the therapy we developed is effective and if it improves people's quality of life. #introduction #mentalhealthresearch #selfharm #NIHR

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Bethan Copsey @bethancopsey.bsky.social · Jan 31

Consider what to report about your rehabilitation intervention? Here's a newly published TIDieR Rehab checklist
bmjopen.bmj.com/content/14/1...

Enhancing the reporting quality of rehabilitation interventions through an extension of the Template for Intervention Description and Replication (TIDieR): the TIDieR-Rehab checklist and supplementary...

Background Rehabilitation is a complex biopsychosocial process in which multidisciplinary professionals work in collaboration with a person and their family, with the shared objective of enhancing the...

bmjopen.bmj.com

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American Statistical Association History of Statistics @hos-asa.bsky.social · Jan 28

#OTD 28 Jan 1809 Louis-Dominique-Jules Gavarret b (d 30 Aug 1890) An early proponent of the 'statistical method' in medicine, his 1840 book 'Principes de Statistique Médicale' was among the first to describe statistical principles for rigorous clinical trial conduct. /10 🧵

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Marion Campbell @marionkcampbell.bsky.social · Jan 27

An issue that often comes up is how to set a “non-inferiority margin” in a non-inferiority trial and how to ensure it is appropriate 1/8
#MethodologyMonday #109

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