Anne Loft
@anneloftsdu.bsky.social
Principal Investigator at Functional Genomics and Metabolism Unit at SDU (Odense). Dissecting adipose tissue (dys)function through single-cell genomics to uncover cellular mechanisms underlying metabolic health and disease.
Pinned
Anne Loft
@anneloftsdu.bsky.social
· Mar 6
Preprint alert! We used snRNA-seq on adipose tissue from a longitudinal cohort of people undergoing surgury-induced weight loss. True ATLAS team effort
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss
During sustained weight gain, human white adipose tissue undergoes dramatic remodeling that may compromise adipose tissue function and lead to obesity comorbidities such as cardiometabolic disease. Th...
www.biorxiv.org
📣 Check out our recent preprint on bioRxiv on cellular changes in adipose tissue in response to different weight loss modalities 📣
📢 PhD Position in Functional Genomics 🧬
Join my international team at the Functional Genomics & Metabolism Research Unit at the University of Southern Denmark 🇩🇰 to explore cardiometabolic disease using single-cell sequencing-based technologies 💥
👉 Apply here: lnkd.in/duPR-B6k
Join my international team at the Functional Genomics & Metabolism Research Unit at the University of Southern Denmark 🇩🇰 to explore cardiometabolic disease using single-cell sequencing-based technologies 💥
👉 Apply here: lnkd.in/duPR-B6k
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July 11, 2025 at 11:33 AM
📢 PhD Position in Functional Genomics 🧬
Join my international team at the Functional Genomics & Metabolism Research Unit at the University of Southern Denmark 🇩🇰 to explore cardiometabolic disease using single-cell sequencing-based technologies 💥
👉 Apply here: lnkd.in/duPR-B6k
Join my international team at the Functional Genomics & Metabolism Research Unit at the University of Southern Denmark 🇩🇰 to explore cardiometabolic disease using single-cell sequencing-based technologies 💥
👉 Apply here: lnkd.in/duPR-B6k
Check out our new roadmap for single cell analyses of adipose tissue at @natmetabolism.nature.com 🧐 Thrilled to share our work put together by great colleagues from Adipose Bionetwork in @humancellatlas.org 🤩 Huge thanks to my fellow co-coordinators @smandrup.bsky.social Evan Rosen and Margo Emont
May 14, 2025 at 9:15 AM
Check out our new roadmap for single cell analyses of adipose tissue at @natmetabolism.nature.com 🧐 Thrilled to share our work put together by great colleagues from Adipose Bionetwork in @humancellatlas.org 🤩 Huge thanks to my fellow co-coordinators @smandrup.bsky.social Evan Rosen and Margo Emont
📣 Check out our recent preprint on bioRxiv on cellular changes in adipose tissue in response to different weight loss modalities 📣
Preprint alert! We used snRNA-seq on adipose tissue from a longitudinal cohort of people undergoing surgury-induced weight loss. True ATLAS team effort
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss
During sustained weight gain, human white adipose tissue undergoes dramatic remodeling that may compromise adipose tissue function and lead to obesity comorbidities such as cardiometabolic disease. Th...
www.biorxiv.org
March 6, 2025 at 9:52 AM
📣 Check out our recent preprint on bioRxiv on cellular changes in adipose tissue in response to different weight loss modalities 📣
Enjoying all aspects of #MetabolismInAction2022: interesting research 🤓 great discussions with dedicated colleagues 🤩 a fantastic venue 💥 and the tasty (H)ugo Spritz served by @MelinaClaussnit at the PI pub🥂😅
@novonordiskfond @ScienceCluster @ATLAS_SDU @bmbSDU
@novonordiskfond @ScienceCluster @ATLAS_SDU @bmbSDU
March 6, 2025 at 9:33 AM
Enjoying all aspects of #MetabolismInAction2022: interesting research 🤓 great discussions with dedicated colleagues 🤩 a fantastic venue 💥 and the tasty (H)ugo Spritz served by @MelinaClaussnit at the PI pub🥂😅
@novonordiskfond @ScienceCluster @ATLAS_SDU @bmbSDU
@novonordiskfond @ScienceCluster @ATLAS_SDU @bmbSDU
Enjoying a fabelous BBQ get-together in the fantastic danish summer 🤩 @ATLAS_SDU @bmbSDU
March 6, 2025 at 9:33 AM
Enjoying a fabelous BBQ get-together in the fantastic danish summer 🤩 @ATLAS_SDU @bmbSDU
Really honored to receive the 'Deutsche Leberstiftung Preis 2022' together with @Ana_Jim_Alf and Stephan Herzig for our @Cell_Metabolism work on hepatocyte fate in NASH. Thanks to everyone involved @helmholtz_diabc @ATLAS_SDU @NATsdu
March 6, 2025 at 9:32 AM
Really honored to receive the 'Deutsche Leberstiftung Preis 2022' together with @Ana_Jim_Alf and Stephan Herzig for our @Cell_Metabolism work on hepatocyte fate in NASH. Thanks to everyone involved @helmholtz_diabc @ATLAS_SDU @NATsdu
Thanks to @sciencenewsdk for highlighting our research on how the immune system impacts on fasting metabolism 🤓 #fasting #immunesystem #health #metabolism
@CarattiGX @FiskerSchmidt @JanTuckermann @helmholtz_diabc @ATLAS_SDU @NATsdu
x.com/sciencenewsdk/…
@CarattiGX @FiskerSchmidt @JanTuckermann @helmholtz_diabc @ATLAS_SDU @NATsdu
x.com/sciencenewsdk/…
March 6, 2025 at 9:32 AM
Thanks to @sciencenewsdk for highlighting our research on how the immune system impacts on fasting metabolism 🤓 #fasting #immunesystem #health #metabolism
@CarattiGX @FiskerSchmidt @JanTuckermann @helmholtz_diabc @ATLAS_SDU @NATsdu
x.com/sciencenewsdk/…
@CarattiGX @FiskerSchmidt @JanTuckermann @helmholtz_diabc @ATLAS_SDU @NATsdu
x.com/sciencenewsdk/…
Come join our fabulous research unit in Odense 🤩 this inventive guy has my strongest personal recommendations 😄
x.com/FiskerSchmidt/…
x.com/FiskerSchmidt/…
March 6, 2025 at 9:32 AM
Come join our fabulous research unit in Odense 🤩 this inventive guy has my strongest personal recommendations 😄
x.com/FiskerSchmidt/…
x.com/FiskerSchmidt/…
If you are interested in understanding how transcription factors and cofactors work 🤓, this is a great opportunity to get supervision from a brilliant and super nice guy 🤩
x.com/RSiersbaek/sta…
x.com/RSiersbaek/sta…
March 6, 2025 at 9:32 AM
If you are interested in understanding how transcription factors and cofactors work 🤓, this is a great opportunity to get supervision from a brilliant and super nice guy 🤩
x.com/RSiersbaek/sta…
x.com/RSiersbaek/sta…
Join our research unit and get the chance to be supervised by these guaranteed cool and nice PI's 🤩
x.com/FiskerSchmidt/…
x.com/FiskerSchmidt/…
March 6, 2025 at 9:32 AM
Join our research unit and get the chance to be supervised by these guaranteed cool and nice PI's 🤩
x.com/FiskerSchmidt/…
x.com/FiskerSchmidt/…
Interested in dissecting TF networks of brown adipocytes? Some tips to how this can be done (including new data🧐) with @maja_worm @jespergrud @susmandrup @ATLAS_SDU. Thanks for being a part of this great method collection @WolfrumLab @guertin_lab
bit.ly/3HdIeBO
bit.ly/3HdIeBO
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March 6, 2025 at 9:32 AM
Interested in dissecting TF networks of brown adipocytes? Some tips to how this can be done (including new data🧐) with @maja_worm @jespergrud @susmandrup @ATLAS_SDU. Thanks for being a part of this great method collection @WolfrumLab @guertin_lab
bit.ly/3HdIeBO
bit.ly/3HdIeBO
Spread the word📣 Our work in @Cell_Metabolism showing how GR in macrophages coordinates fasting ketogenesis via hepatocyte GR is now out. Thanks to everyone involved 🥳 @FiskerSchmidt @helmholtz_diabc @JanTuckermann @ATLAS_SDU @bmbSDU @novonordiskfond
x.com/FiskerSchmidt/…
x.com/FiskerSchmidt/…
March 6, 2025 at 9:32 AM
Spread the word📣 Our work in @Cell_Metabolism showing how GR in macrophages coordinates fasting ketogenesis via hepatocyte GR is now out. Thanks to everyone involved 🥳 @FiskerSchmidt @helmholtz_diabc @JanTuckermann @ATLAS_SDU @bmbSDU @novonordiskfond
x.com/FiskerSchmidt/…
x.com/FiskerSchmidt/…
Science made easy 😉 Go to @JRNLclub and get our recent @Cell_Metabolism paper on hepatocyte crosstalk in NASH and liver fibrosis served🥳 @helmholtz_diabc @GenomicsUnit @ATLAS_SDU @NATsdu
x.com/JRNLclub/statu…
x.com/JRNLclub/statu…
March 6, 2025 at 9:32 AM
Science made easy 😉 Go to @JRNLclub and get our recent @Cell_Metabolism paper on hepatocyte crosstalk in NASH and liver fibrosis served🥳 @helmholtz_diabc @GenomicsUnit @ATLAS_SDU @NATsdu
x.com/JRNLclub/statu…
x.com/JRNLclub/statu…
Our work on hepatocyte fate in NASH in @Cell_Metabolism was highligted as one of the important omics-directed discoveries in liver fibrosis research in 2021 by @NatRevGastroHep 💪🤩 Thanks once again @Ana_Jim_Alf @helmholtz_diabc @ATLAS_SDU @novonordiskfond
x.com/NatRevGastroHe…
x.com/NatRevGastroHe…
March 6, 2025 at 9:32 AM
Our work on hepatocyte fate in NASH in @Cell_Metabolism was highligted as one of the important omics-directed discoveries in liver fibrosis research in 2021 by @NatRevGastroHep 💪🤩 Thanks once again @Ana_Jim_Alf @helmholtz_diabc @ATLAS_SDU @novonordiskfond
x.com/NatRevGastroHe…
x.com/NatRevGastroHe…
Finally back together at the #bringmebackfestival with favorite unit members from the @GenomicsUnit. Even got a chance to reuse my Octoberfest costume 🍻 Thanks for making this possible @bmbSDU @NATsdu 🤩🙌
x.com/MajkenSiers/st…
x.com/MajkenSiers/st…
March 6, 2025 at 9:32 AM
Finally back together at the #bringmebackfestival with favorite unit members from the @GenomicsUnit. Even got a chance to reuse my Octoberfest costume 🍻 Thanks for making this possible @bmbSDU @NATsdu 🤩🙌
x.com/MajkenSiers/st…
x.com/MajkenSiers/st…
Proud to announce our new paper on hepatocyte 'fate' in #NASH and liver fibrosis in @Cell_Metabolism. Special thanks to @Ana_Jim_Alf, Stephan Herzig and other great colleagues at @helmholtz_diabc @bmbSDU @ATLAS_SDU 💪. Now in perfect mood for #ENGDEN 🇩🇰⚽️🏆🍾
x.com/Ana_Jim_Alf/st…
x.com/Ana_Jim_Alf/st…
March 6, 2025 at 9:32 AM
Proud to announce our new paper on hepatocyte 'fate' in #NASH and liver fibrosis in @Cell_Metabolism. Special thanks to @Ana_Jim_Alf, Stephan Herzig and other great colleagues at @helmholtz_diabc @bmbSDU @ATLAS_SDU 💪. Now in perfect mood for #ENGDEN 🇩🇰⚽️🏆🍾
x.com/Ana_Jim_Alf/st…
x.com/Ana_Jim_Alf/st…
Favourite postdoc teammates @BManiyadath and @AjeethaJo rocking our football Boot Camp. Thanks to all @GenomicsUnit members for arranging a much-awaited and memorable get together event 🥳
x.com/susmandrup/sta…
x.com/susmandrup/sta…
March 6, 2025 at 9:32 AM
Favourite postdoc teammates @BManiyadath and @AjeethaJo rocking our football Boot Camp. Thanks to all @GenomicsUnit members for arranging a much-awaited and memorable get together event 🥳
x.com/susmandrup/sta…
x.com/susmandrup/sta…
Fantastic to be "back" with old friends and colleagues at the @helmholtz_diabc and great fun to be a part of the Flash Talk competition. Thanks for an amazing conference!
x.com/helmholtz_diab…
x.com/helmholtz_diab…
March 6, 2025 at 9:32 AM
Fantastic to be "back" with old friends and colleagues at the @helmholtz_diabc and great fun to be a part of the Flash Talk competition. Thanks for an amazing conference!
x.com/helmholtz_diab…
x.com/helmholtz_diab…