April Hayes
@aprilhayes.bsky.social
(she/her) postdoc @ Uni of Exeter in Cornwall 🌊mainly stress out bacteria and track AMR. big fan of the sea, reading, & sunsets 🌞
Reposted by April Hayes
It’s not only medications—environmental chemicals can also inadvertently harm our gut microbes. Excited to have contributed a bit to this important study!
Our paper mapping the effects of hundreds of pesticides and industrial chemicals on gut bacteria is out in @natmicrobiol.nature.com today!
Turns out many such chemicals, although labelled as 'fungicides' or similar, can inadvertently inhibit friendly gut bacteria.
www.nature.com/articles/s41...
Turns out many such chemicals, although labelled as 'fungicides' or similar, can inadvertently inhibit friendly gut bacteria.
www.nature.com/articles/s41...
November 26, 2025 at 1:02 PM
It’s not only medications—environmental chemicals can also inadvertently harm our gut microbes. Excited to have contributed a bit to this important study!
Reposted by April Hayes
🚨‼️ New paper alert!
‘Sewers to Seas: exploring pathogens and antimicrobial resistance on microplastics from hospital wastewater to marine environments’
FULL ARTICLE: www.sciencedirect.com/science/arti...
➡️ Check out @pml.ac.uk’s coverage: pml.ac.uk/news/micropl...
‘Sewers to Seas: exploring pathogens and antimicrobial resistance on microplastics from hospital wastewater to marine environments’
FULL ARTICLE: www.sciencedirect.com/science/arti...
➡️ Check out @pml.ac.uk’s coverage: pml.ac.uk/news/micropl...
Microplastics pose a human health risk in more ways than one
New study shows that microplastics in the natural environment are colonized by pathogenic and antimicrobial resistant bacteria. The study team calls for urgent action for waste management and strongly
pml.ac.uk
November 25, 2025 at 11:47 AM
🚨‼️ New paper alert!
‘Sewers to Seas: exploring pathogens and antimicrobial resistance on microplastics from hospital wastewater to marine environments’
FULL ARTICLE: www.sciencedirect.com/science/arti...
➡️ Check out @pml.ac.uk’s coverage: pml.ac.uk/news/micropl...
‘Sewers to Seas: exploring pathogens and antimicrobial resistance on microplastics from hospital wastewater to marine environments’
FULL ARTICLE: www.sciencedirect.com/science/arti...
➡️ Check out @pml.ac.uk’s coverage: pml.ac.uk/news/micropl...
Reposted by April Hayes
Great to see our @exeter.ac.uk and @pml.ac.uk research highlighted in @uk.theconversation.com 🤟🙏
➡️ theconversation.com/plastic-bio-...
➡️ theconversation.com/plastic-bio-...
November 24, 2025 at 1:20 PM
Great to see our @exeter.ac.uk and @pml.ac.uk research highlighted in @uk.theconversation.com 🤟🙏
➡️ theconversation.com/plastic-bio-...
➡️ theconversation.com/plastic-bio-...
Reposted by April Hayes
Are you looking for a wild PhD opportunity? 🦠🧵
There are several opportunities to join the Wild Microbiome Lab in 2026! Scroll for more information, or visit the link below for full project descriptions and application information👇
xavharrison.github.io
There are several opportunities to join the Wild Microbiome Lab in 2026! Scroll for more information, or visit the link below for full project descriptions and application information👇
xavharrison.github.io
November 24, 2025 at 9:09 AM
Are you looking for a wild PhD opportunity? 🦠🧵
There are several opportunities to join the Wild Microbiome Lab in 2026! Scroll for more information, or visit the link below for full project descriptions and application information👇
xavharrison.github.io
There are several opportunities to join the Wild Microbiome Lab in 2026! Scroll for more information, or visit the link below for full project descriptions and application information👇
xavharrison.github.io
Reposted by April Hayes
Exciting PhD position on algal-driven metal remediation with Dr Michiel Vos and collaborators at the University of Exeter. This project combines plant and microbial ecology, and geochemistry to develop innovative biological solutions for metal pollution
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
NERC RED-ALERT CDT: Green Rivers: harnessing freshwater algae for bioremediation and critical metal recovery. at University of Exeter on FindAPhD.com
PhD Project - NERC RED-ALERT CDT: Green Rivers: harnessing freshwater algae for bioremediation and critical metal recovery. at University of Exeter, listed on FindAPhD.com
www.findaphd.com
November 24, 2025 at 10:25 AM
Exciting PhD position on algal-driven metal remediation with Dr Michiel Vos and collaborators at the University of Exeter. This project combines plant and microbial ecology, and geochemistry to develop innovative biological solutions for metal pollution
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by April Hayes
📢 New paper in @natcomms.nature.com
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes
doi.org/10.1038/s414...
Thrilled to share this massive global effort led by H.M. Martiny, @patrickmunk.bsky.social, F. Aarestrup & the Global Sewage Consortium
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes
doi.org/10.1038/s414...
Thrilled to share this massive global effort led by H.M. Martiny, @patrickmunk.bsky.social, F. Aarestrup & the Global Sewage Consortium
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes - Nature Communications
Antimicrobial resistance genes that have been mobilized between bacterial species represent a subset of the naturally occurring resistome. Here, the authors compare the abundance, diversity and geogra...
doi.org
November 23, 2025 at 11:18 AM
📢 New paper in @natcomms.nature.com
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes
doi.org/10.1038/s414...
Thrilled to share this massive global effort led by H.M. Martiny, @patrickmunk.bsky.social, F. Aarestrup & the Global Sewage Consortium
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes
doi.org/10.1038/s414...
Thrilled to share this massive global effort led by H.M. Martiny, @patrickmunk.bsky.social, F. Aarestrup & the Global Sewage Consortium
Reposted by April Hayes
A lot has happened since our first announcement of #ExE2026, an evolutionary ecology conference hosted by @uniexecec.bsky.social in #Cornwall from June 29 to July 3 2026.
Have a look at our new website to see our confirmed plenary speakers, the mid-conference excursions, and more.
👉 evoxeco.uk 👈
Have a look at our new website to see our confirmed plenary speakers, the mid-conference excursions, and more.
👉 evoxeco.uk 👈
November 21, 2025 at 4:50 PM
A lot has happened since our first announcement of #ExE2026, an evolutionary ecology conference hosted by @uniexecec.bsky.social in #Cornwall from June 29 to July 3 2026.
Have a look at our new website to see our confirmed plenary speakers, the mid-conference excursions, and more.
👉 evoxeco.uk 👈
Have a look at our new website to see our confirmed plenary speakers, the mid-conference excursions, and more.
👉 evoxeco.uk 👈
Reposted by April Hayes
Imagine we could travel back in time ⏪⌛️to explore the world of bacterial pathogens before humans discovered and industrialised antibiotics
We just did that to study the history of #AMR spread @science.org
doi.org/10.1126/scie...
If you like time travel & biology, this 🧵is for you👇
We just did that to study the history of #AMR spread @science.org
doi.org/10.1126/scie...
If you like time travel & biology, this 🧵is for you👇
Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance
Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data predati...
doi.org
October 6, 2025 at 10:42 AM
Imagine we could travel back in time ⏪⌛️to explore the world of bacterial pathogens before humans discovered and industrialised antibiotics
We just did that to study the history of #AMR spread @science.org
doi.org/10.1126/scie...
If you like time travel & biology, this 🧵is for you👇
We just did that to study the history of #AMR spread @science.org
doi.org/10.1126/scie...
If you like time travel & biology, this 🧵is for you👇
Reposted by April Hayes
Happy to share our new AMR resource which has phenotypic AMR (usually MIC data) collected from publications and databases. This is paired with assemblies and annotations
We're excited for users who might train new models, find phenotype/genotype mismatches, or any other use
We're excited for users who might train new models, find phenotype/genotype mismatches, or any other use
Antimicrobial resistance (AMR) is a growing health threat, making infections harder to treat and complicating routine medical care.
EMBL-EBI’s new AMR portal brings together laboratory resistance data and bacterial genomes in one open platform.
#WAAW2025 #ActOnAMR
www.ebi.ac.uk/about/news/t...
🧬💻
EMBL-EBI’s new AMR portal brings together laboratory resistance data and bacterial genomes in one open platform.
#WAAW2025 #ActOnAMR
www.ebi.ac.uk/about/news/t...
🧬💻
A new gateway to global antimicrobial resistance data
New online portal connects bacterial genomes with experimental resistance data to support antimicrobial resistance research.
www.ebi.ac.uk
November 19, 2025 at 12:27 PM
Happy to share our new AMR resource which has phenotypic AMR (usually MIC data) collected from publications and databases. This is paired with assemblies and annotations
We're excited for users who might train new models, find phenotype/genotype mismatches, or any other use
We're excited for users who might train new models, find phenotype/genotype mismatches, or any other use
Reposted by April Hayes
New PhD position in my lab at @uniofbath.bsky.social (with both @tweethinking.bsky.social & Dr Bethan Littleford-Colquhoun)!
We're looking for someone keen on bioinformatics and microbiome evolution.
Important info below on eligibility & URSA competition funding👇
www.findaphd.com/phds/project...
We're looking for someone keen on bioinformatics and microbiome evolution.
Important info below on eligibility & URSA competition funding👇
www.findaphd.com/phds/project...
The overlapping microbiome: ecology, function and resilience beyond species boundaries at University of Bath on FindAPhD.com
PhD Project - The overlapping microbiome: ecology, function and resilience beyond species boundaries at University of Bath, listed on FindAPhD.com
www.findaphd.com
November 12, 2025 at 1:20 PM
New PhD position in my lab at @uniofbath.bsky.social (with both @tweethinking.bsky.social & Dr Bethan Littleford-Colquhoun)!
We're looking for someone keen on bioinformatics and microbiome evolution.
Important info below on eligibility & URSA competition funding👇
www.findaphd.com/phds/project...
We're looking for someone keen on bioinformatics and microbiome evolution.
Important info below on eligibility & URSA competition funding👇
www.findaphd.com/phds/project...
Reposted by April Hayes
Congrats @fullam.bsky.social @pangenomics.bsky.social @borklab.bsky.social & team(s). Great to see this published!
proGenomes4: providing 2 million accurately and consistently annotated high-quality prokaryotic genomes: academic.oup.com/nar/article/...
proGenomes4: providing 2 million accurately and consistently annotated high-quality prokaryotic genomes: academic.oup.com/nar/article/...
proGenomes4: providing 2 million accurately and consistently annotated high-quality prokaryotic genomes
Abstract. The pervasive availability of publicly available microbial genomes has opened many new avenues for microbiology research, yet it also demands rob
academic.oup.com
November 20, 2025 at 8:50 AM
Congrats @fullam.bsky.social @pangenomics.bsky.social @borklab.bsky.social & team(s). Great to see this published!
proGenomes4: providing 2 million accurately and consistently annotated high-quality prokaryotic genomes: academic.oup.com/nar/article/...
proGenomes4: providing 2 million accurately and consistently annotated high-quality prokaryotic genomes: academic.oup.com/nar/article/...
Reposted by April Hayes
We have a new preprint modeling the regulatory networks of efflux pumps to predict the evolution of multidrug resistance in P. aeruginosa. Also explore cross-resistance, collateral sensitivity & loss of resistance. With @suvamroy.bsky.social @elibbyscience.bsky.social www.biorxiv.org/content/10.1...
Forecasting multi-trait resistance evolution under antibiotic stress
Many bacteria rely on efflux pumps to survive antibiotic stress, and exposure to antibiotics often leads to mutations in pump genes or their regulators that increase pump expression. Predicting the sp...
www.biorxiv.org
October 20, 2025 at 6:21 AM
We have a new preprint modeling the regulatory networks of efflux pumps to predict the evolution of multidrug resistance in P. aeruginosa. Also explore cross-resistance, collateral sensitivity & loss of resistance. With @suvamroy.bsky.social @elibbyscience.bsky.social www.biorxiv.org/content/10.1...
Reposted by April Hayes
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Liverpool on Fin...
PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...
www.findaphd.com
November 18, 2025 at 9:38 AM
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Reposted by April Hayes
PhD studentship opportunity! Join us at St Andrews to study the factors controlling plasmid transmission in the gut. Competition-funded as part of the EASTBIO DTP, co-supervised with Dr Jaclyn Pearson. Please share & pass on to anyone interested! 🦠🧫 Deadline 15th December👇
www.findaphd.com
November 18, 2025 at 11:41 AM
PhD studentship opportunity! Join us at St Andrews to study the factors controlling plasmid transmission in the gut. Competition-funded as part of the EASTBIO DTP, co-supervised with Dr Jaclyn Pearson. Please share & pass on to anyone interested! 🦠🧫 Deadline 15th December👇
Reposted by April Hayes
‘The latest surveillance data found that the number of antibiotic-resistant infections in 2024 equated to an average of nearly 400 newly reported cases a week.’
www.theguardian.com/society/2025...
www.theguardian.com/society/2025...
Deaths linked to antibiotic-resistant superbugs rose 17% in England in 2024
Data also shows an average of nearly 400 newly reported cases of antibiotic-resistant infections a week last year
www.theguardian.com
November 13, 2025 at 11:27 PM
‘The latest surveillance data found that the number of antibiotic-resistant infections in 2024 equated to an average of nearly 400 newly reported cases a week.’
www.theguardian.com/society/2025...
www.theguardian.com/society/2025...
Reposted by April Hayes
**PhD opportunity @uniexecec.bsky.social** How is immunogenetic variation maintained in the wild?
Why are alleles that increase disease susceptibility maintained in populations, when natural selection should eliminate them?
Why are alleles that increase disease susceptibility maintained in populations, when natural selection should eliminate them?
November 15, 2025 at 6:48 PM
**PhD opportunity @uniexecec.bsky.social** How is immunogenetic variation maintained in the wild?
Why are alleles that increase disease susceptibility maintained in populations, when natural selection should eliminate them?
Why are alleles that increase disease susceptibility maintained in populations, when natural selection should eliminate them?
Reposted by April Hayes
Our contribution to this special issue: a review on data analysis of human gut microbiome data from global populations
www.cell.com/trends/micro...
www.cell.com/trends/micro...
Analyzing human gut microbiome data from global populations: challenges and resources
Research on the human gut microbiome is expanding rapidly; yet, most published studies
focus on populations from high-income regions such as North America and Europe. Underrepresentation
of population...
www.cell.com
November 12, 2025 at 2:13 AM
Our contribution to this special issue: a review on data analysis of human gut microbiome data from global populations
www.cell.com/trends/micro...
www.cell.com/trends/micro...
Reposted by April Hayes
Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 11, 2025 at 5:15 PM
Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by April Hayes
A glitch in the matrix? No! I have another PhD available on temperature and AMR, this time with @swbiodtp.bsky.social. Join a friendly group (padpadpadpad.netlify.app/about) in Cornwall to do evolutionary ecology, experimental evolution, and combine phenotyping and sequencing. 🧪🦠 #microsky
November 11, 2025 at 10:15 AM
A glitch in the matrix? No! I have another PhD available on temperature and AMR, this time with @swbiodtp.bsky.social. Join a friendly group (padpadpadpad.netlify.app/about) in Cornwall to do evolutionary ecology, experimental evolution, and combine phenotyping and sequencing. 🧪🦠 #microsky
Reposted by April Hayes
Strain displacement in microbiomes via ecological competition www.nature.com/articles/s41... #jcampubs
Strain displacement in microbiomes via ecological competition - Nature Microbiology
Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.
www.nature.com
November 10, 2025 at 4:49 PM
Strain displacement in microbiomes via ecological competition www.nature.com/articles/s41... #jcampubs
Reposted by April Hayes
Functional redundancy matters: the more overlapping microbial functions you have, the more resilient your #microbiome. We showed a strong negative correlation between redundancy loss and increase in #antimicrobial resistance protein upon #drug treatment of microbiomes.
@quadraminstitute.bsky.social
@quadraminstitute.bsky.social
Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social
rdcu.be/eMmcT
@quadraminstitute.bsky.social
rdcu.be/eMmcT
Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs
Nature Communications - Here, the authors systematically map metaproteomic responses of ex vivo human gut microbiota to common therapeutics, identifying several drug classes inducing strong...
rdcu.be
October 29, 2025 at 10:22 AM
Functional redundancy matters: the more overlapping microbial functions you have, the more resilient your #microbiome. We showed a strong negative correlation between redundancy loss and increase in #antimicrobial resistance protein upon #drug treatment of microbiomes.
@quadraminstitute.bsky.social
@quadraminstitute.bsky.social
Reposted by April Hayes
Are you, or someone you know, looking for a PhD, starting in Oct 2026?
Do you like bacteria, genomics & puzzles?🦠🧬🧩
Do you wanna work in a cutting edge of science, with some awesome people @quadraminstitute.bsky.social?
Please apply or share by 2 Dec 🗓️
#PhDposition #academicsky
Find out more ⬇️
Do you like bacteria, genomics & puzzles?🦠🧬🧩
Do you wanna work in a cutting edge of science, with some awesome people @quadraminstitute.bsky.social?
Please apply or share by 2 Dec 🗓️
#PhDposition #academicsky
Find out more ⬇️
PhD Out of order: investigating genetic and environmental drivers of genome rearrangement (LANGRIDGE_Q26DTP) 2026/27 | UEA
PhD Out of order: investigating genetic and environmental drivers of genome rearrangement (LANGRIDGE_Q26DTP) 2026/27 | UEA
www.uea.ac.uk
October 17, 2025 at 7:04 AM
Are you, or someone you know, looking for a PhD, starting in Oct 2026?
Do you like bacteria, genomics & puzzles?🦠🧬🧩
Do you wanna work in a cutting edge of science, with some awesome people @quadraminstitute.bsky.social?
Please apply or share by 2 Dec 🗓️
#PhDposition #academicsky
Find out more ⬇️
Do you like bacteria, genomics & puzzles?🦠🧬🧩
Do you wanna work in a cutting edge of science, with some awesome people @quadraminstitute.bsky.social?
Please apply or share by 2 Dec 🗓️
#PhDposition #academicsky
Find out more ⬇️
Reposted by April Hayes
Countless drugs & chemicals now coexist in the environment, mixtures "that may be quietly shaping the evolution of antibiotic resistance."
The fantastic Dr April Hayes explains how:
theconversation.com/growing-cocktail-of-medicines-in-worlds-waterways-could-be-fuelling-antibiotic-resistance-266945
The fantastic Dr April Hayes explains how:
theconversation.com/growing-cocktail-of-medicines-in-worlds-waterways-could-be-fuelling-antibiotic-resistance-266945
Growing cocktail of medicines in world’s waterways could be fuelling antibiotic resistance
Every flush sends traces of our medicines into rivers. When antibiotics mix with common drugs like painkillers or hormones, bacteria can evolve to resist treatment.
theconversation.com
October 14, 2025 at 2:34 PM
Countless drugs & chemicals now coexist in the environment, mixtures "that may be quietly shaping the evolution of antibiotic resistance."
The fantastic Dr April Hayes explains how:
theconversation.com/growing-cocktail-of-medicines-in-worlds-waterways-could-be-fuelling-antibiotic-resistance-266945
The fantastic Dr April Hayes explains how:
theconversation.com/growing-cocktail-of-medicines-in-worlds-waterways-could-be-fuelling-antibiotic-resistance-266945
I wrote a piece for The Conversation that came out today focused on our new study but also in general about mixtures of drugs in the environment and what that could mean for AMR -
theconversation.com/growing-cock...
theconversation.com/growing-cock...
Growing cocktail of medicines in world’s waterways could be fuelling antibiotic resistance
Every flush sends traces of our medicines into rivers. When antibiotics mix with common drugs like painkillers or hormones, bacteria can evolve to resist treatment.
theconversation.com
October 14, 2025 at 2:02 PM
I wrote a piece for The Conversation that came out today focused on our new study but also in general about mixtures of drugs in the environment and what that could mean for AMR -
theconversation.com/growing-cock...
theconversation.com/growing-cock...
how do non-antibiotic drugs act in mixture with ciprofloxacin? we found in our recent study doi.org/10.1093/isme... that these NADs enhance selection for AMR within complex bacterial communities. we tested this mixture at environmental concs, and identified effects on growth, intI1, and other genes
October 14, 2025 at 2:00 PM
how do non-antibiotic drugs act in mixture with ciprofloxacin? we found in our recent study doi.org/10.1093/isme... that these NADs enhance selection for AMR within complex bacterial communities. we tested this mixture at environmental concs, and identified effects on growth, intI1, and other genes