Augustus (Gus) Pendleton
@augustuspendle1.bsky.social
Microbes 🤝 Lakes 🤝 Computers. Schmidt Lab @ Cornell. 🏳️🌈Scientist, 🇮🇪Fulbright, NOAA Davidson Fellow. Code-obsessed cat owner who likes to be outside.
https://gus-pendleton.github.io/
https://gus-pendleton.github.io/
Pinned
Our new interactive tool: MicrobeMapper – Schmidt Lab
Play with microbial data from Lake Ontario!
marschmilab.github.io
New blog post from the Schmidt Lab! Play around with environmental and microbial data from Lake Ontario, and make some pretty maps!
marschmilab.github.io/blog/microbe...
#rstats #microbiology #ecology #limnology #shiny
marschmilab.github.io/blog/microbe...
#rstats #microbiology #ecology #limnology #shiny
Learned a very painful statistics lesson today (after investing a whole day of analysis)
February 13, 2026 at 8:00 PM
Learned a very painful statistics lesson today (after investing a whole day of analysis)
Reposted by Augustus (Gus) Pendleton
I am seeking a postdoc to join my group at UCLA -- ideally the candidate would have some experience in either population genetics or microbes/microbiome (computational background needed). We have a range of projects and are happy to tailer to your interests. Please dm/email me if interested.
February 12, 2026 at 7:18 PM
I am seeking a postdoc to join my group at UCLA -- ideally the candidate would have some experience in either population genetics or microbes/microbiome (computational background needed). We have a range of projects and are happy to tailer to your interests. Please dm/email me if interested.
Survived the 50km Winona Tourathon last Saturday, all in sub-zero temps! Skied an hour longer than planned but super happy with my 5th-place finish.
February 9, 2026 at 3:55 PM
Survived the 50km Winona Tourathon last Saturday, all in sub-zero temps! Skied an hour longer than planned but super happy with my 5th-place finish.
Reposted by Augustus (Gus) Pendleton
First paper of my PhD @doerrlab.bsky.social is up! We characterized meropenem tolerance in Enterobacterales species, and then further dissected tolerance mechanisms in Klebsiella pneumoniae. journals.plos.org/plospathogen...
Prevalence and mechanisms of high-level carbapenem antibiotic tolerance in clinical isolates of Klebsiella pneumoniae
Author summary Bacteria can survive exposure to antibiotics by constantly repairing cellular damage induced by the drug. This “antibiotic tolerance” enables diverse bacteria to survive long enough to ...
journals.plos.org
February 3, 2026 at 6:07 PM
First paper of my PhD @doerrlab.bsky.social is up! We characterized meropenem tolerance in Enterobacterales species, and then further dissected tolerance mechanisms in Klebsiella pneumoniae. journals.plos.org/plospathogen...
Reposted by Augustus (Gus) Pendleton
“We found that using AI assistance led to a statistically significant decrease in mastery.”
Props to Anthropic for studying the effects of their creation and reporting results that are not probably what they wished for
www.anthropic.com/research/AI-...
Props to Anthropic for studying the effects of their creation and reporting results that are not probably what they wished for
www.anthropic.com/research/AI-...
How AI assistance impacts the formation of coding skills
Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.
www.anthropic.com
January 31, 2026 at 3:50 AM
“We found that using AI assistance led to a statistically significant decrease in mastery.”
Props to Anthropic for studying the effects of their creation and reporting results that are not probably what they wished for
www.anthropic.com/research/AI-...
Props to Anthropic for studying the effects of their creation and reporting results that are not probably what they wished for
www.anthropic.com/research/AI-...
Reposted by Augustus (Gus) Pendleton
We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.
1/n
1/n
Intro to Bedder – The Quinlan Lab
quinlanlab.org
December 2, 2025 at 2:28 AM
Reposted by Augustus (Gus) Pendleton
We have an open position for a bioinformatics/theoretical microbial ecology PhD student to study viral strategies in the global Microverse! Join us at the @microverse.bsky.social at @uni-jena.de, please apply through this link:
jobs.uni-jena.de/jobposting/9...
jobs.uni-jena.de/jobposting/9...
PhD student bioinformatics: Viral strategies in the global Microverse
jobs.uni-jena.de
January 29, 2026 at 12:08 PM
We have an open position for a bioinformatics/theoretical microbial ecology PhD student to study viral strategies in the global Microverse! Join us at the @microverse.bsky.social at @uni-jena.de, please apply through this link:
jobs.uni-jena.de/jobposting/9...
jobs.uni-jena.de/jobposting/9...
I am having fun with networks!
January 15, 2026 at 8:24 PM
I am having fun with networks!
Ecologists 🗣️
I want to study cooccurence of abundant ASVs (~1000) with a subset of abundant ASVs (~100). Tons of tools for this, with a specific corrections for sparsity and compositionality. But my data aren't sparse (all have high prevalence) nor compositional (absolute-abundance corrected). (1\2)
I want to study cooccurence of abundant ASVs (~1000) with a subset of abundant ASVs (~100). Tons of tools for this, with a specific corrections for sparsity and compositionality. But my data aren't sparse (all have high prevalence) nor compositional (absolute-abundance corrected). (1\2)
January 15, 2026 at 4:45 PM
Ecologists 🗣️
I want to study cooccurence of abundant ASVs (~1000) with a subset of abundant ASVs (~100). Tons of tools for this, with a specific corrections for sparsity and compositionality. But my data aren't sparse (all have high prevalence) nor compositional (absolute-abundance corrected). (1\2)
I want to study cooccurence of abundant ASVs (~1000) with a subset of abundant ASVs (~100). Tons of tools for this, with a specific corrections for sparsity and compositionality. But my data aren't sparse (all have high prevalence) nor compositional (absolute-abundance corrected). (1\2)
Reposted by Augustus (Gus) Pendleton
The Department of Homeland Security is refusing to release information on 3 detained Oglala Lakota tribal members who are being held at Fort Snelling, a former concentration camp for Native people, unless the tribe enters into an immigration agreement with ICE.
Oglala Sioux Tribe accuses federal authorities of treaty violation after four members detained by ICE
“Members of the Oglala Sioux Tribe are United States citizens. We are the first Americans.”
www.wjtv.com
January 15, 2026 at 4:05 AM
The Department of Homeland Security is refusing to release information on 3 detained Oglala Lakota tribal members who are being held at Fort Snelling, a former concentration camp for Native people, unless the tribe enters into an immigration agreement with ICE.
Reposted by Augustus (Gus) Pendleton
This is a vetted fundraiser for the family of Renee Good, the woman who was killed by ICE in Minneapolis.
www.gofundme.com/f/support-fo...
www.gofundme.com/f/support-fo...
Donate to Support for Renee Good’s wife and son, organized by Mattie Weiss
Please support the wife and son of Renee Good as they grapple with the devastating … Mattie Weiss needs your support for Support for Renee Good’s wife and son
www.gofundme.com
January 8, 2026 at 2:29 AM
This is a vetted fundraiser for the family of Renee Good, the woman who was killed by ICE in Minneapolis.
www.gofundme.com/f/support-fo...
www.gofundme.com/f/support-fo...
Reposted by Augustus (Gus) Pendleton
Latest work on the Diadema pathogen and its seasonal occurrence at a time series site
Host-independent persistence of the Diadema antillarum Scuticociliatosis Philaster clade in coastal environments https://www.biorxiv.org/content/10.64898/2026.01.07.698123v1
January 8, 2026 at 1:39 PM
Latest work on the Diadema pathogen and its seasonal occurrence at a time series site
Reposted by Augustus (Gus) Pendleton
New paper up on bioRxiv! This is my third and hopefully final paper on rarefaction. It's still better than the other available methods.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Rarefaction is better than robust Aitchison PCA and other compositional data analysis methods at controlling for uneven sequencing effort
Amplicon sequencing typically results in a wide distribution in the number of sequences obtained from each sample. How best to account for this variation has been a persistent problem in the microbial...
www.biorxiv.org
January 7, 2026 at 6:58 PM
New paper up on bioRxiv! This is my third and hopefully final paper on rarefaction. It's still better than the other available methods.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Augustus (Gus) Pendleton
We are recruiting several PhD students. If you are interested in conservation conflicts, population ecology, quantitative ecology, or biodiversity, check these projects out (links in the thread, feel free to reach out):
December 28, 2025 at 11:36 PM
We are recruiting several PhD students. If you are interested in conservation conflicts, population ecology, quantitative ecology, or biodiversity, check these projects out (links in the thread, feel free to reach out):
Reposted by Augustus (Gus) Pendleton
The sporulation phosphorelay protein Spo0B is membrane localized in Paenibacillus! The transmembrane domain appears to increase interaction with relay partners. Congrats to former lab undergrad @isabellalin.bsky.social and her grad mentor @cassidyprints.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
journals.asm.org
December 30, 2025 at 1:50 PM
The sporulation phosphorelay protein Spo0B is membrane localized in Paenibacillus! The transmembrane domain appears to increase interaction with relay partners. Congrats to former lab undergrad @isabellalin.bsky.social and her grad mentor @cassidyprints.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Reposted by Augustus (Gus) Pendleton
This work was also our first time doing membrane localization (way to go Cassidy)! And so proud of Bella’s gorgeous Paenibacillus tree showing the distribution of the transmembrane containing Spo0B! Also it’s the lab’s first paper without ribosomes 🫨, but don’t worry - the ribosomes made the Spo0B!
December 30, 2025 at 2:01 PM
This work was also our first time doing membrane localization (way to go Cassidy)! And so proud of Bella’s gorgeous Paenibacillus tree showing the distribution of the transmembrane containing Spo0B! Also it’s the lab’s first paper without ribosomes 🫨, but don’t worry - the ribosomes made the Spo0B!
Looking for advice: we’re trying to extract HMW DNA from PES filters, so no bead beating. Pretty low biomass. Troubleshooting phenol-chloroform extractions right now but would love any advice or protocols if people are willing to share!
December 16, 2025 at 1:44 PM
Looking for advice: we’re trying to extract HMW DNA from PES filters, so no bead beating. Pretty low biomass. Troubleshooting phenol-chloroform extractions right now but would love any advice or protocols if people are willing to share!
Reposted by Augustus (Gus) Pendleton
Love aquatic research, teaching, and outreach? Want to join us at our terrific field station and live on Yellow Bay, Montana? University of Montana seeks a new Director for Flathead Lake Biological Station. Position details here: apply.interfolio.com/178916
December 12, 2025 at 9:00 PM
Love aquatic research, teaching, and outreach? Want to join us at our terrific field station and live on Yellow Bay, Montana? University of Montana seeks a new Director for Flathead Lake Biological Station. Position details here: apply.interfolio.com/178916
My family split it up and baked all of the NYT cookie week cookies. Here are our rankings, if helpful:
1. Dark 'n' Stormy - showstoppers, delicious
2. Vietnamese Coffee Brownies - tasty and easy
3. Coconut Snowballs - yummy and colorful
4. Creme de Menthe - okay flavor, not favorite texture
cont...
1. Dark 'n' Stormy - showstoppers, delicious
2. Vietnamese Coffee Brownies - tasty and easy
3. Coconut Snowballs - yummy and colorful
4. Creme de Menthe - okay flavor, not favorite texture
cont...
December 12, 2025 at 12:20 PM
My family split it up and baked all of the NYT cookie week cookies. Here are our rankings, if helpful:
1. Dark 'n' Stormy - showstoppers, delicious
2. Vietnamese Coffee Brownies - tasty and easy
3. Coconut Snowballs - yummy and colorful
4. Creme de Menthe - okay flavor, not favorite texture
cont...
1. Dark 'n' Stormy - showstoppers, delicious
2. Vietnamese Coffee Brownies - tasty and easy
3. Coconut Snowballs - yummy and colorful
4. Creme de Menthe - okay flavor, not favorite texture
cont...
Very cool work!
Ecologists recognize the importance of integrating across scales, yet our models often target specific scales. Our new paper presents models of population growth that scale up to explain community-level patterns, including interactions of temperature, light & nutrients. doi.org/10.1002/ecm....
December 9, 2025 at 2:52 PM
Very cool work!
Looking for ideas: I have both sequencing data (relative abundances of cyanobacteria in a sample) as well as flow cytometry data (autofluorescence in multiple channels) for many mixed, environmental samples. I want to find fluorescence signatures for a few specific genera.
December 4, 2025 at 7:41 PM
Looking for ideas: I have both sequencing data (relative abundances of cyanobacteria in a sample) as well as flow cytometry data (autofluorescence in multiple channels) for many mixed, environmental samples. I want to find fluorescence signatures for a few specific genera.
Reposted by Augustus (Gus) Pendleton
very cool: hydroacoustics shows "daily migration of both fish and mysid shrimps spanning several hundred meters throughout Lake Superior" -- in the Fall IAGLR Lakes Letter
iaglr.org/ll/2025-4_Fa... 👏
iaglr.org/ll/2025-4_Fa... 👏
December 2, 2025 at 12:10 PM
very cool: hydroacoustics shows "daily migration of both fish and mysid shrimps spanning several hundred meters throughout Lake Superior" -- in the Fall IAGLR Lakes Letter
iaglr.org/ll/2025-4_Fa... 👏
iaglr.org/ll/2025-4_Fa... 👏
Reposted by Augustus (Gus) Pendleton
Starting at 7pm Central I will be streaming from the bottom of the ocean off the coast of Uruguay!
Feel free to join and ask questions.
www.youtube.com/@SchmidtOcean
Feel free to join and ask questions.
www.youtube.com/@SchmidtOcean
Schmidt Ocean
Our Purpose: to excite interest and inform the wise stewardship of our planet.
Our Mission: Catalyze the discoveries needed to understand our ocean, sustain life, and ensure the health of our planet ...
www.youtube.com
November 14, 2025 at 7:39 PM
Starting at 7pm Central I will be streaming from the bottom of the ocean off the coast of Uruguay!
Feel free to join and ask questions.
www.youtube.com/@SchmidtOcean
Feel free to join and ask questions.
www.youtube.com/@SchmidtOcean
Reposted by Augustus (Gus) Pendleton
Love to see community action against this AI nonsense! neighborhoodview.org/2025/11/13/d...
November 14, 2025 at 11:42 AM
Love to see community action against this AI nonsense! neighborhoodview.org/2025/11/13/d...
Reposted by Augustus (Gus) Pendleton
Excited to recruit a new PhD student for Fall 2026 in my lab at Cornell! Looking for someone interested in evolutionary genomics + fisheries/conservation applications. Quick timeline this year—reach out soon. More details: www.therkildsenlab.org/join-us.html
Join Us
The lab of Nina Overgaard Therkildsen in the Department of Natural Resources and the Environment at Cornell University invites applications for a PhD position starting in Fall 2026. Our group works...
www.therkildsenlab.org
November 14, 2025 at 2:17 AM
Excited to recruit a new PhD student for Fall 2026 in my lab at Cornell! Looking for someone interested in evolutionary genomics + fisheries/conservation applications. Quick timeline this year—reach out soon. More details: www.therkildsenlab.org/join-us.html