Bat Bor
@batbilegbor.bsky.social
Faculty at ADA ForsythResearch | Bor Lab | Microbiologist | Saccharibacteria (TM7) | Episymbionts | Runner | Climber | Cyclist
Pinned
Bat Bor
@batbilegbor.bsky.social
· Jun 3
Exciting progress! In our new preprint, we show that episymbiont Saccharibacteria can directly modulate epithelial immunity—a big step in understanding how these elusive microbes interact with the human host. Kudos to Deepak Chouhan and our amazing collaborators! www.biorxiv.org/content/10.1...
Reposted by Bat Bor
ADA Forsyth faculty are joining the 2026 Rocky Mountain Dental Convention speaker lineup! Our researchers will share new insights on periodontal regeneration, oral–systemic health, developmental defects, and the oral microbiome.
October 28, 2025 at 4:13 PM
ADA Forsyth faculty are joining the 2026 Rocky Mountain Dental Convention speaker lineup! Our researchers will share new insights on periodontal regeneration, oral–systemic health, developmental defects, and the oral microbiome.
Reposted by Bat Bor
Very interesting work from Ibarlosa and colleagues regarding functional amyloid forming proteins in prokaryotic immunity.
www.nature.com/articles/s41...
Check out our News & Views summary of the work as well!
rdcu.be/eBHxh
www.nature.com/articles/s41...
Check out our News & Views summary of the work as well!
rdcu.be/eBHxh
Amyloids in bacterial antiphage defence
Nature Microbiology - Bacterial prions form amyloids in response to phage infection and induce cell death to prevent viral replication, similar to the processes in fungi and across the tree of life.
rdcu.be
August 21, 2025 at 2:06 PM
Very interesting work from Ibarlosa and colleagues regarding functional amyloid forming proteins in prokaryotic immunity.
www.nature.com/articles/s41...
Check out our News & Views summary of the work as well!
rdcu.be/eBHxh
www.nature.com/articles/s41...
Check out our News & Views summary of the work as well!
rdcu.be/eBHxh
Reposted by Bat Bor
Cell Geometry Limits Bacterial Metabolic Efficiency www.biorxiv.org/content/10.1... #jcampubs
August 15, 2025 at 4:06 PM
Cell Geometry Limits Bacterial Metabolic Efficiency www.biorxiv.org/content/10.1... #jcampubs
Reposted by Bat Bor
For the first time, scientists have performed targeted mutations on an episymbiosis-determining pathway. In a new study on Saccharibacteria, AFI researchers used advanced techniques to observe pili that drive motility and host attachment.
@batbilegbor.bsky.social
forsyth.org/saccharibact...
@batbilegbor.bsky.social
forsyth.org/saccharibact...
August 15, 2025 at 8:36 PM
For the first time, scientists have performed targeted mutations on an episymbiosis-determining pathway. In a new study on Saccharibacteria, AFI researchers used advanced techniques to observe pili that drive motility and host attachment.
@batbilegbor.bsky.social
forsyth.org/saccharibact...
@batbilegbor.bsky.social
forsyth.org/saccharibact...
Excited to be presenting at the 3rd Annual Scientific Conference of the Society of Mongolian Researchers in the USA! 🇲🇳🧬 It’s a great space to connect and support Mongolian researchers. 10/11-10/12 in DC. #MongolianScience #ResearchCommunity www.mongolianresearchers.org/2025-annual-...
July 11, 2025 at 4:07 PM
Excited to be presenting at the 3rd Annual Scientific Conference of the Society of Mongolian Researchers in the USA! 🇲🇳🧬 It’s a great space to connect and support Mongolian researchers. 10/11-10/12 in DC. #MongolianScience #ResearchCommunity www.mongolianresearchers.org/2025-annual-...
Reposted by Bat Bor
New paper out! We searched for cargo across thousands of Type 11 Secretion Systems (T11SS) in Proteobacteria and uncovered 2,500+ predicted secreted proteins, including 6 novel cargo types, with experimental verification of a new surface lipoprotein, Pls. doi.org/10.1099/mgen.0.001406
May 21, 2025 at 4:40 PM
New paper out! We searched for cargo across thousands of Type 11 Secretion Systems (T11SS) in Proteobacteria and uncovered 2,500+ predicted secreted proteins, including 6 novel cargo types, with experimental verification of a new surface lipoprotein, Pls. doi.org/10.1099/mgen.0.001406
Reposted by Bat Bor
📣 We are proud of the publication of the second paper of @bbaker24.bsky.social PhD thesis. In collaboration with friends in Halifax we have studied the difficult question of the phylogeny of the DPANN archaea, composed of several phyla of highly reduced, fast-evolving epiparasites 🧵
rdcu.be/erkkU
rdcu.be/erkkU
Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free-living euryarchaeal-like ancestors
Nature Microbiology - Phylogenetic reconstructions with conserved protein markers from the 11 known DPANN phyla reveal their monophyletic placement within the Euryarchaeota.
rdcu.be
June 17, 2025 at 12:35 PM
📣 We are proud of the publication of the second paper of @bbaker24.bsky.social PhD thesis. In collaboration with friends in Halifax we have studied the difficult question of the phylogeny of the DPANN archaea, composed of several phyla of highly reduced, fast-evolving epiparasites 🧵
rdcu.be/erkkU
rdcu.be/erkkU
Reposted by Bat Bor
ASM staff is on site and hard at work with final preparations for #ASMicrobe! We can’t wait to see you there—and we're happy announce that the curfew has been lifted!
June 17, 2025 at 10:07 PM
ASM staff is on site and hard at work with final preparations for #ASMicrobe! We can’t wait to see you there—and we're happy announce that the curfew has been lifted!
Exciting progress! In our new preprint, we show that episymbiont Saccharibacteria can directly modulate epithelial immunity—a big step in understanding how these elusive microbes interact with the human host. Kudos to Deepak Chouhan and our amazing collaborators! www.biorxiv.org/content/10.1...
June 3, 2025 at 12:30 PM
Exciting progress! In our new preprint, we show that episymbiont Saccharibacteria can directly modulate epithelial immunity—a big step in understanding how these elusive microbes interact with the human host. Kudos to Deepak Chouhan and our amazing collaborators! www.biorxiv.org/content/10.1...
Reposted by Bat Bor
Hi everyone, I tried assembling a Microbiome & friends starter pack.
🦠🧫🔬
Still learning to use bluesky and might have missed you, let me know if you would like to be included.
go.bsky.app/Fq36egy
🦠🧫🔬
Still learning to use bluesky and might have missed you, let me know if you would like to be included.
go.bsky.app/Fq36egy
October 19, 2024 at 4:09 PM
Hi everyone, I tried assembling a Microbiome & friends starter pack.
🦠🧫🔬
Still learning to use bluesky and might have missed you, let me know if you would like to be included.
go.bsky.app/Fq36egy
🦠🧫🔬
Still learning to use bluesky and might have missed you, let me know if you would like to be included.
go.bsky.app/Fq36egy
Reposted by Bat Bor
A new preprint from the lab in collaboration with Feng Jiang.
www.biorxiv.org/content/10.1...
This is a thread for you if you're interested in secretion systems, phages, and evolution.
The extracellular contractile injection system (eCIS) is a mysterious microbial toxin delivery system.
www.biorxiv.org/content/10.1...
This is a thread for you if you're interested in secretion systems, phages, and evolution.
The extracellular contractile injection system (eCIS) is a mysterious microbial toxin delivery system.
May 14, 2025 at 11:14 AM
A new preprint from the lab in collaboration with Feng Jiang.
www.biorxiv.org/content/10.1...
This is a thread for you if you're interested in secretion systems, phages, and evolution.
The extracellular contractile injection system (eCIS) is a mysterious microbial toxin delivery system.
www.biorxiv.org/content/10.1...
This is a thread for you if you're interested in secretion systems, phages, and evolution.
The extracellular contractile injection system (eCIS) is a mysterious microbial toxin delivery system.
Reposted by Bat Bor
New publication!
Our findings reveal that the specificity of several FISH probes is compromised, with cross-species hybridization being more common than previously assumed as more genomic data becomes available. #microbiology
onlinelibrary.wiley.com/doi/10.1111/...
Our findings reveal that the specificity of several FISH probes is compromised, with cross-species hybridization being more common than previously assumed as more genomic data becomes available. #microbiology
onlinelibrary.wiley.com/doi/10.1111/...
Shining Light on Oral Biofilm Fluorescence In Situ Hybridization (FISH): Probing the Accuracy of In Situ Biogeography Studies
The oral biofilm has been instrumental in advancing microbial research and enhancing our understanding of oral health and disease. Recent developments in next-generation sequencing have provided deta...
onlinelibrary.wiley.com
May 2, 2025 at 5:02 PM
New publication!
Our findings reveal that the specificity of several FISH probes is compromised, with cross-species hybridization being more common than previously assumed as more genomic data becomes available. #microbiology
onlinelibrary.wiley.com/doi/10.1111/...
Our findings reveal that the specificity of several FISH probes is compromised, with cross-species hybridization being more common than previously assumed as more genomic data becomes available. #microbiology
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Bat Bor
"That telomere phages are so prevalent means that they are a selective force, one that we know little about. We now want to understand how the telomere-toxin is secreted and also understand how this ‘telocin’ wheedles its way into unsuspecting bacterial neighbors”
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Telomere bacteriophages are widespread and equip their bacterial hosts with potent interbacterial weapons
Klebsiella host strains infected with telomere phages can grow to be the dominant lineage in mixed populations.
www.science.org
May 1, 2025 at 10:04 PM
"That telomere phages are so prevalent means that they are a selective force, one that we know little about. We now want to understand how the telomere-toxin is secreted and also understand how this ‘telocin’ wheedles its way into unsuspecting bacterial neighbors”
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Bat Bor
Out in Nature today: A new immune signaling molecule, His-ADPR, is produced by defensive TIR domain proteins in bacteria to protect from phage
Joint work with the Tamulaitienė and Kranzusch labs
www.nature.com/articles/s41...
Congrats Carmel Avraham, Dziugas Sabonis, Renee Chang and co-authors!
Joint work with the Tamulaitienė and Kranzusch labs
www.nature.com/articles/s41...
Congrats Carmel Avraham, Dziugas Sabonis, Renee Chang and co-authors!
April 30, 2025 at 6:44 PM
Out in Nature today: A new immune signaling molecule, His-ADPR, is produced by defensive TIR domain proteins in bacteria to protect from phage
Joint work with the Tamulaitienė and Kranzusch labs
www.nature.com/articles/s41...
Congrats Carmel Avraham, Dziugas Sabonis, Renee Chang and co-authors!
Joint work with the Tamulaitienė and Kranzusch labs
www.nature.com/articles/s41...
Congrats Carmel Avraham, Dziugas Sabonis, Renee Chang and co-authors!
Reposted by Bat Bor
For the last few years I've been working on an educational game all about microbiology. Customize your own cell, release it into the world and see how well it survives! The Steam page will be up soon, follow me for updates!🦠 #madewithunity #indiedev #microbiology
December 10, 2024 at 6:07 PM
For the last few years I've been working on an educational game all about microbiology. Customize your own cell, release it into the world and see how well it survives! The Steam page will be up soon, follow me for updates!🦠 #madewithunity #indiedev #microbiology
Reposted by Bat Bor
Many recent viral outbreaks, including SARS-CoV-2 and mpox, feature oral symptoms. A Review in Nature Reviews Immunology discusses antiviral immunity in the oral cavity and presents current mouse models for the study of oral viral infections. �’ https://go.nature.com/49xJlwg
December 10, 2024 at 1:55 PM
Many recent viral outbreaks, including SARS-CoV-2 and mpox, feature oral symptoms. A Review in Nature Reviews Immunology discusses antiviral immunity in the oral cavity and presents current mouse models for the study of oral viral infections. �’ https://go.nature.com/49xJlwg
Reposted by Bat Bor
Hi BlueSky friends!
Postdoc(s) available in my lab!
Multiple projects on how bacterial genomic and functional diversity impacts microbial interactions & disease. 🦠🧫
See www.thelewinlab.com/join-us/post... for more information.
Please RT & share.
#Postdoc #Microbiology #OralMicro #VaginalMicro
Postdoc(s) available in my lab!
Multiple projects on how bacterial genomic and functional diversity impacts microbial interactions & disease. 🦠🧫
See www.thelewinlab.com/join-us/post... for more information.
Please RT & share.
#Postdoc #Microbiology #OralMicro #VaginalMicro
October 25, 2024 at 2:46 PM
Hi BlueSky friends!
Postdoc(s) available in my lab!
Multiple projects on how bacterial genomic and functional diversity impacts microbial interactions & disease. 🦠🧫
See www.thelewinlab.com/join-us/post... for more information.
Please RT & share.
#Postdoc #Microbiology #OralMicro #VaginalMicro
Postdoc(s) available in my lab!
Multiple projects on how bacterial genomic and functional diversity impacts microbial interactions & disease. 🦠🧫
See www.thelewinlab.com/join-us/post... for more information.
Please RT & share.
#Postdoc #Microbiology #OralMicro #VaginalMicro
Reposted by Bat Bor
Meteor Shower and Orion in Mongolia 🇲🇳
📸 yin hao
📸 yin hao
December 8, 2024 at 1:31 PM
Meteor Shower and Orion in Mongolia 🇲🇳
📸 yin hao
📸 yin hao
Excited to share our new preprint on the detailed investigation of Type 4 pili in epibiont oral Saccharibacteria! Led by Alex Grossman from our lab, and with Jun Liu (Yale), Jeff McLean (UW) and Xuesong He. Check it out: biorxiv.org/content/10.1...
December 4, 2024 at 11:09 AM
Excited to share our new preprint on the detailed investigation of Type 4 pili in epibiont oral Saccharibacteria! Led by Alex Grossman from our lab, and with Jun Liu (Yale), Jeff McLean (UW) and Xuesong He. Check it out: biorxiv.org/content/10.1...
Reposted by Bat Bor
A TM7 strain protects its host from phage infection:
Episymbiotic Saccharibacteria TM7x modulates the susceptibility of its host bacteria to phage infection and promotes their coexistence
doi.org/10.1073/pnas...
Episymbiotic Saccharibacteria TM7x modulates the susceptibility of its host bacteria to phage infection and promotes their coexistence
doi.org/10.1073/pnas...
April 10, 2024 at 2:56 PM
A TM7 strain protects its host from phage infection:
Episymbiotic Saccharibacteria TM7x modulates the susceptibility of its host bacteria to phage infection and promotes their coexistence
doi.org/10.1073/pnas...
Episymbiotic Saccharibacteria TM7x modulates the susceptibility of its host bacteria to phage infection and promotes their coexistence
doi.org/10.1073/pnas...
Reposted by Bat Bor
Saccharibacteria deploy two distinct Type IV pili, driving episymbiosis, host competition, and twitching motility https://www.biorxiv.org/content/10.1101/2024.11.25.624915v1
Saccharibacteria deploy two distinct Type IV pili, driving episymbiosis, host competition, and twitching motility https://www.biorxiv.org/content/10.1101/2024.11.25.624915v1
All cultivated Patescibacteria, or CPR, exist as obligate episymbionts on other microbes. Despite be
www.biorxiv.org
November 26, 2024 at 5:19 AM
Saccharibacteria deploy two distinct Type IV pili, driving episymbiosis, host competition, and twitching motility https://www.biorxiv.org/content/10.1101/2024.11.25.624915v1