Lizzy Rosser
@bcellsrosser.bsky.social
Interested in all things B cells, autoimmunity, nutritional immunology and child health. Located at UCL, ARR department in Division of Medicine.
Reposted by Lizzy Rosser
Single-cell RNA-seq study of blood and synovial fluid from patients with newly diagnosed oligoarthritis and enthesitis-related arthritis provides evidence linking HLA-B27, conventional type 1 dendritic cells, and CD8⁺ T cells within a unified pathogenic axis
A&R
doi.org/10.1002/art....
A&R
doi.org/10.1002/art....
February 6, 2026 at 1:57 PM
Single-cell RNA-seq study of blood and synovial fluid from patients with newly diagnosed oligoarthritis and enthesitis-related arthritis provides evidence linking HLA-B27, conventional type 1 dendritic cells, and CD8⁺ T cells within a unified pathogenic axis
A&R
doi.org/10.1002/art....
A&R
doi.org/10.1002/art....
Thanks for the highlight!
Study sheds new light on sight-threatening arthritis in children
@uclnews.bsky.social
@greatormondst.bsky.social
@moorfields.bsky.social
www.ucl.ac.uk/news/2026/fe...
@uclnews.bsky.social
@greatormondst.bsky.social
@moorfields.bsky.social
www.ucl.ac.uk/news/2026/fe...
Study sheds new light on sight-threatening arthritis in children
A team led by UCL researchers with Great Ormond Street Hospital (GOSH) and Moorfields Eye Hospital, found B cells—alongside T cells—play a key role in arthritis-related eye disease (JIA uveitis), a co...
www.ucl.ac.uk
February 5, 2026 at 3:25 PM
Thanks for the highlight!
Reposted by Lizzy Rosser
Analysis of synovial fluid and tissue samples from rheumatoid arthritis patients undergoing knee arthroplasty showed synovial fluid features reflected findings in the synovial tissue, and could differentiate high & low lymphocytic synovial inflammation
ACR Open Rheumatology
doi.org/10.1002/acr2...
ACR Open Rheumatology
doi.org/10.1002/acr2...
February 4, 2026 at 9:57 PM
Analysis of synovial fluid and tissue samples from rheumatoid arthritis patients undergoing knee arthroplasty showed synovial fluid features reflected findings in the synovial tissue, and could differentiate high & low lymphocytic synovial inflammation
ACR Open Rheumatology
doi.org/10.1002/acr2...
ACR Open Rheumatology
doi.org/10.1002/acr2...
Reposted by Lizzy Rosser
Integrated single-cell analyses of affinity-tested B cells enable the identification of a gene signature to predict antibody affinity @astrazeneca.bsky.social @angelettilab.bsky.social
www.cell.com/cell-systems...
www.cell.com/cell-systems...
Integrated single-cell analyses of affinity-tested B cells enable the identification of a gene signature to predict antibody affinity
Chirichella and colleagues integrated single-cell transcriptomics, BCR sequences,
and affinity measurements to identify High Signature, a gene expression signature
predictive of sub-nanomolar antibodi...
www.cell.com
February 4, 2026 at 8:55 PM
Integrated single-cell analyses of affinity-tested B cells enable the identification of a gene signature to predict antibody affinity @astrazeneca.bsky.social @angelettilab.bsky.social
www.cell.com/cell-systems...
www.cell.com/cell-systems...
Let’s go 💪 beyond excited to be part of this new initiative led by @emmaschambers.bsky.social
I am delighted to introduce the 'ImmunoPause' consortium. This is a collection of immunologists who are working on understanding how the immune system changes during the menopause. An important yet understudied research area.
immunopause.my.canva.site#home
immunopause.my.canva.site#home
Home
immunopause.my.canva.site
February 4, 2026 at 9:06 AM
Let’s go 💪 beyond excited to be part of this new initiative led by @emmaschambers.bsky.social
Our paper retweeted by the @labwaggoner.bsky.social! Maybe we’ve made it to the big time!
Altered B cell activation contributes to the immunopathogenesis of childhood arthritis-associated uveitis @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 3, 2026 at 9:39 PM
Our paper retweeted by the @labwaggoner.bsky.social! Maybe we’ve made it to the big time!
Reposted by Lizzy Rosser
🔬 New research from @uclmedsci.bsky.social, @moorfields.bsky.social & @greatormondst.bsky.social is changing how we understand a sight-threatening condition in children with arthritis - bringing us closer to protecting children’s sight. 👁️
👉 Read the full story on our website:
bit.ly/49SfuQW
👉 Read the full story on our website:
bit.ly/49SfuQW
February 3, 2026 at 10:46 AM
🔬 New research from @uclmedsci.bsky.social, @moorfields.bsky.social & @greatormondst.bsky.social is changing how we understand a sight-threatening condition in children with arthritis - bringing us closer to protecting children’s sight. 👁️
👉 Read the full story on our website:
bit.ly/49SfuQW
👉 Read the full story on our website:
bit.ly/49SfuQW
Very proud that our investigating uveitis pathogenesis in young people living with arthritis is out today @natcomms.nature.com. A real team science effort made possible by collaborations across hospital & researchers with support of patients. Check it out 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Altered B cell activation contributes to the immunopathogenesis of childhood arthritis-associated uveitis - Nature Communications
Juvenile idiopathic arthritis (JIA) associated uveitis can cause vision loss in children, but mechanisms remain unclear. The authors here identify elevated CD19+IgD-CD27- double negative type 1 B cell...
www.nature.com
February 3, 2026 at 12:47 PM
Very proud that our investigating uveitis pathogenesis in young people living with arthritis is out today @natcomms.nature.com. A real team science effort made possible by collaborations across hospital & researchers with support of patients. Check it out 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Lizzy Rosser
"Ever wondered what happens if you remove Tfh cells from established germinal centres?" A great research question from former #ListerFellow @linterman.bsky.social.
🔽 Paper in Science Immunology www.science.org/doi/10.1126/...
⏬ Click and read Michelle's full thread
Congrats to Michelle and team 👏
🔽 Paper in Science Immunology www.science.org/doi/10.1126/...
⏬ Click and read Michelle's full thread
Congrats to Michelle and team 👏
January 26, 2026 at 11:20 AM
"Ever wondered what happens if you remove Tfh cells from established germinal centres?" A great research question from former #ListerFellow @linterman.bsky.social.
🔽 Paper in Science Immunology www.science.org/doi/10.1126/...
⏬ Click and read Michelle's full thread
Congrats to Michelle and team 👏
🔽 Paper in Science Immunology www.science.org/doi/10.1126/...
⏬ Click and read Michelle's full thread
Congrats to Michelle and team 👏
Reposted by Lizzy Rosser
The Royal Society Rosalind Franklin Award is made to support projects that promote women in STEM. Find out more and make your nomination now: #RSMedals #WomenInSTEM https://royalsociety.org/medals-and-prizes/rosalind-franklin-award/
January 21, 2026 at 5:37 PM
The Royal Society Rosalind Franklin Award is made to support projects that promote women in STEM. Find out more and make your nomination now: #RSMedals #WomenInSTEM https://royalsociety.org/medals-and-prizes/rosalind-franklin-award/
Reposted by Lizzy Rosser
Today we celebrate #ListerFellow @nickywhiffin.bsky.social 🤩She's on The Sunday Times Alternative Honours List 2025 for her role in discovering ReNU syndrome and the non-coding variants behind the disorder 👏
Read this fab story of discovery and rapid uptake👉 lister-institute.org.uk/renu-ed-hope...
Read this fab story of discovery and rapid uptake👉 lister-institute.org.uk/renu-ed-hope...
January 14, 2026 at 10:32 AM
Today we celebrate #ListerFellow @nickywhiffin.bsky.social 🤩She's on The Sunday Times Alternative Honours List 2025 for her role in discovering ReNU syndrome and the non-coding variants behind the disorder 👏
Read this fab story of discovery and rapid uptake👉 lister-institute.org.uk/renu-ed-hope...
Read this fab story of discovery and rapid uptake👉 lister-institute.org.uk/renu-ed-hope...
🤩
A new study demonstrates the effectiveness of a widely-used eye injection to manage the previously untreatable rare condition, hypotony (abnormally low eye pressure), in a project by researchers at @ucleye.bsky.social, @moorfields.bsky.social, @uclengineering.bsky.social and @uclmedsci.bsky.social
World-first project shows great promise to treat low eye pressure
A new study demonstrates the effectiveness of a widely-used eye injection to manage the previously untreatable rare condition, hypotony, in a project by clinical researchers at UCL and Moorfields Eye ...
www.ucl.ac.uk
January 12, 2026 at 7:55 PM
🤩
Reposted by Lizzy Rosser
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes. From @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Ciurtin et al. 👉 rupress.org/jem/article/...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
January 12, 2026 at 3:15 PM
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes. From @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Ciurtin et al. 👉 rupress.org/jem/article/...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
Reposted by Lizzy Rosser
Had a great time back at the BSI presenting the first of my post-doc work!
Visit poster 86 today to find out about IgA and lupus at the #bsi2025 and talk to @clairebeesley.bsky.social
December 19, 2025 at 8:15 AM
Had a great time back at the BSI presenting the first of my post-doc work!
Reposted by Lizzy Rosser
Registrations are now open for 'Fuelling the immune response', the 4th UK immunometabolism meeting, led by the BSI Immunometabolism Affinity Group.
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
December 18, 2025 at 9:25 AM
Registrations are now open for 'Fuelling the immune response', the 4th UK immunometabolism meeting, led by the BSI Immunometabolism Affinity Group.
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
Delighted out study was to be included on this list @jem.org have a scroll through and check it out (sex differences in class-switched memory B cells) - hubs.la/Q03YbLjR0
2025: The Year in Experimental Medicine | Journal of Experimental Medicine | Rockefeller University Press
hubs.la
December 18, 2025 at 3:56 PM
Delighted out study was to be included on this list @jem.org have a scroll through and check it out (sex differences in class-switched memory B cells) - hubs.la/Q03YbLjR0
Reposted by Lizzy Rosser
A new UK-led research group, including @ucl.ac.uk's Prof Lucy Wedderburn (@uclchildhealth.bsky.social), Prof Coziana Ciurtin & Dr Polly Livermore, aims to improve arthritis care by defining for the first time what remission truly means. Funded by £3m from Arthritis UK www.ucl.ac.uk/news/2025/de...
Study by new consortium aims to help improve care for arthritis patients
A new UK-led research group, which includes UCL, aims to improve the lives of people with arthritis by defining for the first time what being in remission from the illness truly means.
www.ucl.ac.uk
December 17, 2025 at 12:01 PM
A new UK-led research group, including @ucl.ac.uk's Prof Lucy Wedderburn (@uclchildhealth.bsky.social), Prof Coziana Ciurtin & Dr Polly Livermore, aims to improve arthritis care by defining for the first time what remission truly means. Funded by £3m from Arthritis UK www.ucl.ac.uk/news/2025/de...
Reposted by Lizzy Rosser
Great teaser for forthcoming publication from former #ListerFellow @linterman.bsky.social ⏬
And what a lovely pic to sum up science:
🤝close friendship and collaboration
🧠shared curiosity
🎨fresh data (what a gorgeous backdrop image😍)
🔎new insights and understanding
And what a lovely pic to sum up science:
🤝close friendship and collaboration
🧠shared curiosity
🎨fresh data (what a gorgeous backdrop image😍)
🔎new insights and understanding
What a joy to host Michelle @linterman.bsky.social at the LUMC and spend more time together at the #NVVI!!
She shared wonderful work on ectopic Germinal Centers in the lung (www.pnas.org/doi/10.1073/...) and a new exciting story that I can't wait to see published soon!!
She shared wonderful work on ectopic Germinal Centers in the lung (www.pnas.org/doi/10.1073/...) and a new exciting story that I can't wait to see published soon!!
December 12, 2025 at 10:46 AM
Great teaser for forthcoming publication from former #ListerFellow @linterman.bsky.social ⏬
And what a lovely pic to sum up science:
🤝close friendship and collaboration
🧠shared curiosity
🎨fresh data (what a gorgeous backdrop image😍)
🔎new insights and understanding
And what a lovely pic to sum up science:
🤝close friendship and collaboration
🧠shared curiosity
🎨fresh data (what a gorgeous backdrop image😍)
🔎new insights and understanding
Reposted by Lizzy Rosser
The graphical abstract says it all. Check it out 👇
Congrats to #ListerFellow @nevesjf.bsky.social and the team that figured out the role of TGF-β1 👏
Congrats to #ListerFellow @nevesjf.bsky.social and the team that figured out the role of TGF-β1 👏
Very proud of this amazing work by @diacoman.bsky.social and all the team/collaborators (specially @lukeocyte.bsky.social) that show how ILC3s mediate immune-epithelial interactions via production & activation of TGFb. #ILC #gut #IBD #organoids www.mucosalimmunology.org/article/S193...
ILC3s mediate intestinal immune-epithelial interactions via TGF-β1 activation
Inflammatory Bowel Disease (IBD), which encompasses Crohn’s disease (CD) and ulcerative
colitis (UC), is a multifactorial disease that exhibits abnormal cellular interactions
between the intestinal ep...
www.mucosalimmunology.org
December 4, 2025 at 3:19 PM
The graphical abstract says it all. Check it out 👇
Congrats to #ListerFellow @nevesjf.bsky.social and the team that figured out the role of TGF-β1 👏
Congrats to #ListerFellow @nevesjf.bsky.social and the team that figured out the role of TGF-β1 👏
Reposted by Lizzy Rosser
Well done @maanalayeghi.bsky.social #BSI25
December 4, 2025 at 9:18 PM
Well done @maanalayeghi.bsky.social #BSI25
Yes I’m reposting myself! Vote!!!
Loving #BSI25, especially @ciurtinlab.bsky.social and @emmaschambers.bsky.social highlighting our paper in @jem.org is one of #ArthritisUK top research output of ‘25! If you have 5 minutes, give us a vote (number 5) below, sex differences in the immune system:
www.arthritis-uk.org/our-research...
www.arthritis-uk.org/our-research...
Research Highlight of the Year
Arthritis UK Research Highlight of the Year: celebrate the outstanding work that’s made a real impact over the past year.
www.arthritis-uk.org
December 3, 2025 at 6:19 PM
Yes I’m reposting myself! Vote!!!
Extreeeeemly #proudPI
Second @bcellsrosser.bsky.social talk #BSI25 and so proud to have helped with this amazing project for Vicky's PhD! It's all about the gut ofc 😁👏👏
December 3, 2025 at 12:27 PM
Extreeeeemly #proudPI
Reposted by Lizzy Rosser
If you have 30 seconds pretty please could you vote for our research: 'Option 5. Sex differences in the immune system' at the link below! We truly appreciate your support!! 🔬🌟🙏🏻
Loving #BSI25, especially @ciurtinlab.bsky.social and @emmaschambers.bsky.social highlighting our paper in @jem.org is one of #ArthritisUK top research output of ‘25! If you have 5 minutes, give us a vote (number 5) below, sex differences in the immune system:
www.arthritis-uk.org/our-research...
www.arthritis-uk.org/our-research...
Research Highlight of the Year
Arthritis UK Research Highlight of the Year: celebrate the outstanding work that’s made a real impact over the past year.
www.arthritis-uk.org
December 2, 2025 at 5:51 PM
If you have 30 seconds pretty please could you vote for our research: 'Option 5. Sex differences in the immune system' at the link below! We truly appreciate your support!! 🔬🌟🙏🏻
Very excited to see this very fresh and preliminary data out in the wild #BSI25 and hope many got to see and appreciate - very well done Ben!! 👏💪
@bcellsrosser.bsky.social
@bcellsrosser.bsky.social
December 2, 2025 at 4:06 PM
Reposted by Lizzy Rosser
Very excited to see this very fresh and preliminary data out in the wild #BSI25 and hope many got to see and appreciate - very well done Ben!! 👏💪
@bcellsrosser.bsky.social
@bcellsrosser.bsky.social
December 2, 2025 at 3:39 PM
Very excited to see this very fresh and preliminary data out in the wild #BSI25 and hope many got to see and appreciate - very well done Ben!! 👏💪
@bcellsrosser.bsky.social
@bcellsrosser.bsky.social