Bo Wang
bowang87.bsky.social
Bo Wang
@bowang87.bsky.social
Chief AI Officer @ UHN; Assistant Prof. @ U of Toronto; CIFAR AI Chair @ Vector Institute; AI & Biology
🔥 Unveiling the Future of Genomics with Genome Language Models (gLMs)! 🔥

Our comprehensive review, "Transformers and genome language models," is finally published in Nature Machine Intelligence! ​

Link: nature.com/articles/s42...
Transformers and genome language models - Nature Machine Intelligence
Micaela Consens et al. discuss and review the recent rise of transformer-based and large language models in genomics. They also highlight promising directions for genome language models beyond the tra...
nature.com
March 17, 2025 at 2:58 PM
How can generative AI and Robotics help advance drug discovery?

🚀 Excited to introduce LUMI-lab!
A foundation model-driven Self-Driving Lab (SDL) for autonomous ionizable lipid discovery in mRNA delivery 🤖🔍
February 18, 2025 at 3:08 PM
Agentic AI Meets Medicine!!!

🔬 Excited to announce MedRAX: a groundbreaking Medical Reasoning Agent for Chest X-ray interpretation, now on arXiv!

Paper:https://arxiv.org/abs/2502.02673

Code: github.com/bowang-lab/M...
February 18, 2025 at 2:21 AM
🚀 Introducing scGPT-spatial! 🧬🌍
A game-changing spatial-omic foundation model, built on the powerful scGPT framework with MoE (mixture of experts) and continually pretrained on a massive 30 million spatial single-cell profiles!
February 17, 2025 at 3:52 PM
Reposted by Bo Wang
Our Jan issue is live! nature.com/natmachintell with an article (Yejin Choi et al) and N&V commentary (Molly Crockett) on Delphi, designed to investigate AI moral reasoning. Also read about IntegrateAnyOmics by @bowang87.bsky.social, an unsupervised platform to tackle incomplete multi-omics data.
January 29, 2025 at 4:30 PM
Our first accepted paper in 2025:

🚀 Introducing MorphoDiff: Our new diffusion-based generative pipeline for high-resolution cellular morphology prediction, guided by perturbation signals, now accepted at ICLR 2025!
January 22, 2025 at 9:45 PM
Thrilled that ‘Foundation Models for Biology’ has been named one of the top 7 technologies to watch by
@nature.com ! Thanks for highlighting our scGPT work! Also honored to contribute to such a visionary piece. 2025 will be an exciting year for AI & biology!

www.nature.com/articles/d41...
Self-driving laboratories, advanced immunotherapies and five more technologies to watch in 2025
Sustainability and artificial intelligence dominate our seventh annual round-up of exciting innovations.
www.nature.com
January 20, 2025 at 9:07 PM
How to build a virtual cell is the “Holy Grail” of the biology! A great read from The Atlantic @theatlantic.com ! Also thanks for highlighting our scGPT, the model that started the new wave of foundation models in biology!

www.theatlantic.com/technology/a...
A Virtual Cell Is a ‘Holy Grail’ of Science. It’s Getting Closer.
Large language models may unlock a new and valuable type of research.
www.theatlantic.com
January 10, 2025 at 7:37 PM
Our Orthrus, one of the first RNA foundation models, is on #NeurIPS2024 !!

More details can be seen: x.com/bowang87/sta...
December 17, 2024 at 2:39 PM
Reposted by Bo Wang
Excited to be presenting Orthrus with Ruain Shi and Keren Isaev @karini925.bsky.social today! We will be presenting our spotlight at the workshop on AI for new drug modalities #NeurIPS2024

Come chat about a new approach to mRNA representation learning!
December 15, 2024 at 5:21 PM
Reposted by Bo Wang
Three UHN research projects have received over $4M through the Ontario Research Fund, part of a $92M investment in Ontario research!

Learn how this funding advances:
▶️#MRI tech
▶️#AI for donor lungs
▶️Muscle & joint #health

Congrats to the awardees!
🔗 www.uhnresearch.ca/news/investi...
December 10, 2024 at 4:11 PM
Reposted by Bo Wang
AI: The New Virtual Radiologist 🩻 🫁

Researchers at UHN’s Toronto General Hospital Research Institute are using AI to enhance the accuracy and consistency of organ evaluation for lung #transplantation.

Read more ➡️ www.uhnresearch.ca/news/ai-new-...
December 2, 2024 at 3:57 PM
This is an exciting milestone for our MEDSAM! 🎉 Our paper "Segment Anything in Medical Images" has surpassed 1,000 citations!
November 27, 2024 at 1:47 AM
This is amazing article! Thanks
@erictopol.bsky.social
for highlighting two of our new foundation models for DNA methylation!
A vertical takeoff of life science with #AI LLLMs.
Publication of 10 new foundation models of Proteins, DNA, RNA, methylation, cells, and interactions, evolution, and design in the past couple of weeks!
Unprecedented progress, reviewed in the new Ground Truths
erictopol.substack.com/p/learning-t...
November 26, 2024 at 4:06 AM
thanks @haoyin.bsky.social 🙏🙏
Dr. Bo Wang is on BlueSky now

@bowang87.bsky.social

Follow him if you don't want to miss the coolest AI-Biomedical development!!!😎
November 20, 2024 at 2:41 AM
Large language of life models: foundation models for longevity and aging!
Our lab has been involved in two groundbreaking DNA methylation foundation models: CpGPT and MethylGPT! These “Large Language of Life” models (@erictopol.bsky.social) mark a new era in aging prediction and disease analysis.
November 18, 2024 at 1:54 AM
Reposted by Bo Wang
CpGPT: a Foundation Model for DNA Methylation
www.biorxiv.org/content/10.1...

MethylGPT: a foundation model for the DNA methylome
www.biorxiv.org/content/10.1...

Exciting self supervised models trained on massive cross-platform methylation data by @bowang87.bsky.social lab. 1/
CpGPT: a Foundation Model for DNA Methylation
DNA methylation is a critical epigenetic modification that regulates gene expression and plays a significant role in development and disease processes. Here, we present the Cytosine-phosphate-Guanine ...
www.biorxiv.org
November 14, 2024 at 4:40 PM
Thanks @anshulkundaje.bsky.social ! Look forward to connecting with folks in AI & genomics at bsky!
November 14, 2024 at 4:34 PM