Brandán Pedre
@brandanium.bsky.social
970 followers
300 following
4 posts
I make fluorescent indicators that monitor metabolites and signaling molecules in the cell.
Now @KULeuven, previously in @DKFZ and @VIBLifeSciences.
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Reposted by Brandán Pedre
Dana Reichmann
@danareichmann.bsky.social
· May 19
Thiol-based redox switches: From chemistry to physiology and pathology
Redox reactions have been essential for the emergence of life on Earth, and diverse strategies have evolved for responding to various cellular redox species. These mechanisms are still of vital impor…
meetings.embo.org
Reposted by Brandán Pedre
Reposted by Brandán Pedre
Brandán Pedre
@brandanium.bsky.social
· Feb 25
Nature Chemistry
@natchem.nature.com
· Feb 25
Site-specific activation of the proton pump inhibitor rabeprazole by tetrathiolate zinc centres - Nature Chemistry
Proton pump inhibitors (PPIs) are prodrugs that are activated by protonation in the highly acidic environment of the stomach lining. Now, coordination of PPIs to protein-bound zinc ions is revealed as...
www.nature.com
Reposted by Brandán Pedre
Brandán Pedre
@brandanium.bsky.social
· Nov 25