Clinical & Experimental Immunology
@ceijournal.bsky.social
The journal of #translational #immunology 🔃
British Society for Immunology journal publishing high-quality & impactful research since 1966
British Society for Immunology journal publishing high-quality & impactful research since 1966
🛡️ This #PublishingIntegrityWeek, BSI journals are tackling papermills, promoting AI transparency, DEI & accessibility, and supporting ethical research in immunology.
Read more 👉 https://bit.ly/4odyvAZ
Read more 👉 https://bit.ly/4odyvAZ
November 21, 2025 at 5:05 PM
🛡️ This #PublishingIntegrityWeek, BSI journals are tackling papermills, promoting AI transparency, DEI & accessibility, and supporting ethical research in immunology.
Read more 👉 https://bit.ly/4odyvAZ
Read more 👉 https://bit.ly/4odyvAZ
💙 On #WorldDiabetesDay, explore new insights into immune regulation in childhood #T1D.
An Open Access study in Clinical & Experimental Immunology links Galectin-1 with inflammation & Treg cells in children with type 1 diabetes.
Read more 👉 https://bit.ly/4r3C2Vw
An Open Access study in Clinical & Experimental Immunology links Galectin-1 with inflammation & Treg cells in children with type 1 diabetes.
Read more 👉 https://bit.ly/4r3C2Vw
November 14, 2025 at 10:41 AM
💙 On #WorldDiabetesDay, explore new insights into immune regulation in childhood #T1D.
An Open Access study in Clinical & Experimental Immunology links Galectin-1 with inflammation & Treg cells in children with type 1 diabetes.
Read more 👉 https://bit.ly/4r3C2Vw
An Open Access study in Clinical & Experimental Immunology links Galectin-1 with inflammation & Treg cells in children with type 1 diabetes.
Read more 👉 https://bit.ly/4r3C2Vw
Tomorrow marks #WorldDiabetesDay, check out this Open Access study: a new LIPS assay detects zinc transporter 8 autoantibodies (ZnT8A) quickly, safely, and with minimal blood, helping identify children at risk for type 1 diabetes.
Read more 👉 https://bit.ly/3JBSPhw
Read more 👉 https://bit.ly/3JBSPhw
November 13, 2025 at 6:56 PM
Tomorrow marks #WorldDiabetesDay, check out this Open Access study: a new LIPS assay detects zinc transporter 8 autoantibodies (ZnT8A) quickly, safely, and with minimal blood, helping identify children at risk for type 1 diabetes.
Read more 👉 https://bit.ly/3JBSPhw
Read more 👉 https://bit.ly/3JBSPhw
🧫 Organoids reveal how gut epithelial diversity shapes host–pathogen interactions, enabling study of viruses, bacteria & parasites previously impossible in vitro.
👉 https://bit.ly/422Z96U
##Organoids #GutImmunology #Immunology
👉 https://bit.ly/422Z96U
##Organoids #GutImmunology #Immunology
November 7, 2025 at 10:25 AM
🧫 Organoids reveal how gut epithelial diversity shapes host–pathogen interactions, enabling study of viruses, bacteria & parasites previously impossible in vitro.
👉 https://bit.ly/422Z96U
##Organoids #GutImmunology #Immunology
👉 https://bit.ly/422Z96U
##Organoids #GutImmunology #Immunology
📘 People living with HIV can experience residual immune activation even on ART, raising comorbidity risks.
Krystelle Nganou-Makamdop reviews human studies on anti-inflammatory therapies and future strategies.
👉 https://bit.ly/4g5VMm4
##HIV #Immunology
Krystelle Nganou-Makamdop reviews human studies on anti-inflammatory therapies and future strategies.
👉 https://bit.ly/4g5VMm4
##HIV #Immunology
November 6, 2025 at 1:00 PM
📘 People living with HIV can experience residual immune activation even on ART, raising comorbidity risks.
Krystelle Nganou-Makamdop reviews human studies on anti-inflammatory therapies and future strategies.
👉 https://bit.ly/4g5VMm4
##HIV #Immunology
Krystelle Nganou-Makamdop reviews human studies on anti-inflammatory therapies and future strategies.
👉 https://bit.ly/4g5VMm4
##HIV #Immunology
New study finds IL-17 deficiency may underlie cryptococcosis in HIV-negative “immunocompetent” adults. Could unlock new paths for immunotherapy! 🦠🧬
Open access: https://bit.ly/47rL1Xq
##Immunology #Cryptococcosis #IL17 #InfectiousDiseases
Open access: https://bit.ly/47rL1Xq
##Immunology #Cryptococcosis #IL17 #InfectiousDiseases
October 30, 2025 at 2:43 PM
New study finds IL-17 deficiency may underlie cryptococcosis in HIV-negative “immunocompetent” adults. Could unlock new paths for immunotherapy! 🦠🧬
Open access: https://bit.ly/47rL1Xq
##Immunology #Cryptococcosis #IL17 #InfectiousDiseases
Open access: https://bit.ly/47rL1Xq
##Immunology #Cryptococcosis #IL17 #InfectiousDiseases
Heading to #BSACI2025? 🫁
We’ve been looking at how allergens ramp up IL-18 & IL-18Rα in Th2/Th17 cells in allergic asthma, and what that means for therapy.
👉 https://bit.ly/4qgknJE
##Allergy #Immunology
We’ve been looking at how allergens ramp up IL-18 & IL-18Rα in Th2/Th17 cells in allergic asthma, and what that means for therapy.
👉 https://bit.ly/4qgknJE
##Allergy #Immunology
October 17, 2025 at 9:40 AM
Heading to #BSACI2025? 🫁
We’ve been looking at how allergens ramp up IL-18 & IL-18Rα in Th2/Th17 cells in allergic asthma, and what that means for therapy.
👉 https://bit.ly/4qgknJE
##Allergy #Immunology
We’ve been looking at how allergens ramp up IL-18 & IL-18Rα in Th2/Th17 cells in allergic asthma, and what that means for therapy.
👉 https://bit.ly/4qgknJE
##Allergy #Immunology
Going to #BSACI2025? Let’s talk neutrophils!
🧬 Our new open-access review covers their surprising roles in allergy and potential therapeutic targets.
👉 https://bit.ly/3GReFeX
##Allergy #Immunology
🧬 Our new open-access review covers their surprising roles in allergy and potential therapeutic targets.
👉 https://bit.ly/3GReFeX
##Allergy #Immunology
October 16, 2025 at 12:25 PM
Going to #BSACI2025? Let’s talk neutrophils!
🧬 Our new open-access review covers their surprising roles in allergy and potential therapeutic targets.
👉 https://bit.ly/3GReFeX
##Allergy #Immunology
🧬 Our new open-access review covers their surprising roles in allergy and potential therapeutic targets.
👉 https://bit.ly/3GReFeX
##Allergy #Immunology
🏆Following last week's #NobelPrize announcement, we've pulled together a new virtual issue.
🔎Check it out for must-read articles on peripheral immune tolerance published in the BSI journals: immunology.org/publications...
🔎Check it out for must-read articles on peripheral immune tolerance published in the BSI journals: immunology.org/publications...
The 2025 Nobel Prize Virtual Issue | British Society for Immunology
immunology.org
October 13, 2025 at 2:31 PM
🏆Following last week's #NobelPrize announcement, we've pulled together a new virtual issue.
🔎Check it out for must-read articles on peripheral immune tolerance published in the BSI journals: immunology.org/publications...
🔎Check it out for must-read articles on peripheral immune tolerance published in the BSI journals: immunology.org/publications...
HYCO-3, a dual-action CO-releaser/Nrf2 activator, modulates immune cells by reducing pro-inflammatory cytokines & antigen presentation. Promising strategy for autoimmune & chronic inflammatory disorders.
Read more 👉 https://bit.ly/3Gf7UDk
##Immunology #Autoimmunity
Read more 👉 https://bit.ly/3Gf7UDk
##Immunology #Autoimmunity
October 9, 2025 at 2:33 PM
HYCO-3, a dual-action CO-releaser/Nrf2 activator, modulates immune cells by reducing pro-inflammatory cytokines & antigen presentation. Promising strategy for autoimmune & chronic inflammatory disorders.
Read more 👉 https://bit.ly/3Gf7UDk
##Immunology #Autoimmunity
Read more 👉 https://bit.ly/3Gf7UDk
##Immunology #Autoimmunity
Neuro-Behçet’s disease is a rare but severe manifestation of Behçet’s. This review highlights advances in diagnosis, biomarkers (IL-6, autoantibodies, BAFF), and immunopathogenesis.
🔗 https://bit.ly/4gZDyU0
🔗 https://bit.ly/4gZDyU0
October 3, 2025 at 3:49 PM
Neuro-Behçet’s disease is a rare but severe manifestation of Behçet’s. This review highlights advances in diagnosis, biomarkers (IL-6, autoantibodies, BAFF), and immunopathogenesis.
🔗 https://bit.ly/4gZDyU0
🔗 https://bit.ly/4gZDyU0
🩺 New review highlights immunological insights in liver transplantation from host–graft responses to biomarkers predicting rejection, emphasizing the quest for operational tolerance.
🔗 https://bit.ly/46xnt4l
##LiverTransplant #Immunology
🔗 https://bit.ly/46xnt4l
##LiverTransplant #Immunology
October 3, 2025 at 10:40 AM
🩺 New review highlights immunological insights in liver transplantation from host–graft responses to biomarkers predicting rejection, emphasizing the quest for operational tolerance.
🔗 https://bit.ly/46xnt4l
##LiverTransplant #Immunology
🔗 https://bit.ly/46xnt4l
##LiverTransplant #Immunology
🔬 New study shows 2B4 (CD244) binds Staphylococcus aureus exotoxin SEB, driving allergic inflammation.
2B4 knockout mice had reduced inflammation → a potential therapeutic target.
Read here: https://bit.ly/4my2B1e
##Immunology #Staphylococcus #Inflammation
2B4 knockout mice had reduced inflammation → a potential therapeutic target.
Read here: https://bit.ly/4my2B1e
##Immunology #Staphylococcus #Inflammation
September 28, 2025 at 11:53 AM
🔬 New study shows 2B4 (CD244) binds Staphylococcus aureus exotoxin SEB, driving allergic inflammation.
2B4 knockout mice had reduced inflammation → a potential therapeutic target.
Read here: https://bit.ly/4my2B1e
##Immunology #Staphylococcus #Inflammation
2B4 knockout mice had reduced inflammation → a potential therapeutic target.
Read here: https://bit.ly/4my2B1e
##Immunology #Staphylococcus #Inflammation
🦴 New study identifies CFI, an NKT cell–related gene, as a promising biomarker in osteoarthritis.
Validated in patients & mouse models, CFI knockdown reduced inflammation.
🔗 https://bit.ly/42Lz1OT
##Osteoarthritis #Biomarkers #Immunology
Validated in patients & mouse models, CFI knockdown reduced inflammation.
🔗 https://bit.ly/42Lz1OT
##Osteoarthritis #Biomarkers #Immunology
September 25, 2025 at 5:09 PM
🦴 New study identifies CFI, an NKT cell–related gene, as a promising biomarker in osteoarthritis.
Validated in patients & mouse models, CFI knockdown reduced inflammation.
🔗 https://bit.ly/42Lz1OT
##Osteoarthritis #Biomarkers #Immunology
Validated in patients & mouse models, CFI knockdown reduced inflammation.
🔗 https://bit.ly/42Lz1OT
##Osteoarthritis #Biomarkers #Immunology
Persistent immune activation remains a challenge for people living with #HIV, even with viral control.
On #HIVandAgeing Awareness Day, discover strategies to improve long-term immune health
Read the study here👉 https://bit.ly/4g5VMm4
On #HIVandAgeing Awareness Day, discover strategies to improve long-term immune health
Read the study here👉 https://bit.ly/4g5VMm4
September 18, 2025 at 9:50 AM
Persistent immune activation remains a challenge for people living with #HIV, even with viral control.
On #HIVandAgeing Awareness Day, discover strategies to improve long-term immune health
Read the study here👉 https://bit.ly/4g5VMm4
On #HIVandAgeing Awareness Day, discover strategies to improve long-term immune health
Read the study here👉 https://bit.ly/4g5VMm4
A novel Fc-modified anti-haptoglobin mAb shows non-inferior efficacy to IVIG in an ITP monkey model at much lower doses, potentially reducing treatment burden.
Open Access 👉 https://bit.ly/4mN8dWJ
#Immunology #ITP #MonoclonalAntibodies
Open Access 👉 https://bit.ly/4mN8dWJ
#Immunology #ITP #MonoclonalAntibodies
September 15, 2025 at 12:21 PM
A novel Fc-modified anti-haptoglobin mAb shows non-inferior efficacy to IVIG in an ITP monkey model at much lower doses, potentially reducing treatment burden.
Open Access 👉 https://bit.ly/4mN8dWJ
#Immunology #ITP #MonoclonalAntibodies
Open Access 👉 https://bit.ly/4mN8dWJ
#Immunology #ITP #MonoclonalAntibodies
Attending the UK inflammation 2025 meeting? #BSIInflammation2025
If your research explores innate immunity & inflammation, consider submitting to Clinical & Experimental Immunology, showcase your work to a global audience!
Learn more🔗 https://bit.ly/443pf8s
If your research explores innate immunity & inflammation, consider submitting to Clinical & Experimental Immunology, showcase your work to a global audience!
Learn more🔗 https://bit.ly/443pf8s
September 12, 2025 at 10:32 AM
Attending the UK inflammation 2025 meeting? #BSIInflammation2025
If your research explores innate immunity & inflammation, consider submitting to Clinical & Experimental Immunology, showcase your work to a global audience!
Learn more🔗 https://bit.ly/443pf8s
If your research explores innate immunity & inflammation, consider submitting to Clinical & Experimental Immunology, showcase your work to a global audience!
Learn more🔗 https://bit.ly/443pf8s
Heading to the UK Inflammation 2025 meeting? #BSIInflammation2025
Check out how sulforaphane targets NLRP3 inflammasomes to relieve inflammation in CP/CPPS, preclinical insights that could inform future therapies.
Read the full study🔗 https://bit.ly/45QNNpI
Check out how sulforaphane targets NLRP3 inflammasomes to relieve inflammation in CP/CPPS, preclinical insights that could inform future therapies.
Read the full study🔗 https://bit.ly/45QNNpI
September 11, 2025 at 11:40 AM
Heading to the UK Inflammation 2025 meeting? #BSIInflammation2025
Check out how sulforaphane targets NLRP3 inflammasomes to relieve inflammation in CP/CPPS, preclinical insights that could inform future therapies.
Read the full study🔗 https://bit.ly/45QNNpI
Check out how sulforaphane targets NLRP3 inflammasomes to relieve inflammation in CP/CPPS, preclinical insights that could inform future therapies.
Read the full study🔗 https://bit.ly/45QNNpI
HTNV infection impacts CD8+ MAIT cells in HFRS patients, causing both activation and depletion.
These cells show antiviral properties, highlighting a key role in disease defence.
Open Access 👉 https://bit.ly/4g4SoYA
#HFRS #Immunology
These cells show antiviral properties, highlighting a key role in disease defence.
Open Access 👉 https://bit.ly/4g4SoYA
#HFRS #Immunology
September 10, 2025 at 10:55 AM
HTNV infection impacts CD8+ MAIT cells in HFRS patients, causing both activation and depletion.
These cells show antiviral properties, highlighting a key role in disease defence.
Open Access 👉 https://bit.ly/4g4SoYA
#HFRS #Immunology
These cells show antiviral properties, highlighting a key role in disease defence.
Open Access 👉 https://bit.ly/4g4SoYA
#HFRS #Immunology
Reposted by Clinical & Experimental Immunology
CD56 on immune and tumor cells: what is the known and beyond? @ceijournal.bsky.social
academic.oup.com/cei/advance-...
academic.oup.com/cei/advance-...
September 4, 2025 at 1:54 AM
CD56 on immune and tumor cells: what is the known and beyond? @ceijournal.bsky.social
academic.oup.com/cei/advance-...
academic.oup.com/cei/advance-...
🧠 Altered B-cell subsets and cytokine expression are linked to disease activity in CIDP.
Findings suggest immune signatures could help guide diagnosis and prognosis.
🔗 https://bit.ly/3rzemhN
##CIDP #Neuroimmunology
Findings suggest immune signatures could help guide diagnosis and prognosis.
🔗 https://bit.ly/3rzemhN
##CIDP #Neuroimmunology
September 5, 2025 at 9:53 AM
🧠 Altered B-cell subsets and cytokine expression are linked to disease activity in CIDP.
Findings suggest immune signatures could help guide diagnosis and prognosis.
🔗 https://bit.ly/3rzemhN
##CIDP #Neuroimmunology
Findings suggest immune signatures could help guide diagnosis and prognosis.
🔗 https://bit.ly/3rzemhN
##CIDP #Neuroimmunology
Alzheimer’s disease is one of the greatest health challenges of our time.
This #WorldAlzheimersMonth, Clinical & Experimental Immunology calls on immunologists investigating Alzheimer’s & immunity to share their findings with us.
Submit here: https://bit.ly/443pf8s
@alzheimerssoc.bsky.social
This #WorldAlzheimersMonth, Clinical & Experimental Immunology calls on immunologists investigating Alzheimer’s & immunity to share their findings with us.
Submit here: https://bit.ly/443pf8s
@alzheimerssoc.bsky.social
September 3, 2025 at 4:51 PM
Alzheimer’s disease is one of the greatest health challenges of our time.
This #WorldAlzheimersMonth, Clinical & Experimental Immunology calls on immunologists investigating Alzheimer’s & immunity to share their findings with us.
Submit here: https://bit.ly/443pf8s
@alzheimerssoc.bsky.social
This #WorldAlzheimersMonth, Clinical & Experimental Immunology calls on immunologists investigating Alzheimer’s & immunity to share their findings with us.
Submit here: https://bit.ly/443pf8s
@alzheimerssoc.bsky.social
💉🌐 Oral vaccines are cheap, easy & life-saving, but why do they underperform in the places they’re needed most?
This paper highlights multifactorial causes & urges tailored solutions for equity in immunisation.
👉 https://bit.ly/42aACy3
##ImmunisationAwarenessMonth
This paper highlights multifactorial causes & urges tailored solutions for equity in immunisation.
👉 https://bit.ly/42aACy3
##ImmunisationAwarenessMonth
August 29, 2025 at 12:50 PM
💉🌐 Oral vaccines are cheap, easy & life-saving, but why do they underperform in the places they’re needed most?
This paper highlights multifactorial causes & urges tailored solutions for equity in immunisation.
👉 https://bit.ly/42aACy3
##ImmunisationAwarenessMonth
This paper highlights multifactorial causes & urges tailored solutions for equity in immunisation.
👉 https://bit.ly/42aACy3
##ImmunisationAwarenessMonth
Important insights this #NationalPsoriasisMonth.
🧪 Even with long-term anti-TNF (infliximab) treatment, patients with psoriasis & psoriatic arthritis show immune cell shifts, suggesting ongoing systemic inflammation.
🔗 https://bit.ly/47Ny4sD
🧪 Even with long-term anti-TNF (infliximab) treatment, patients with psoriasis & psoriatic arthritis show immune cell shifts, suggesting ongoing systemic inflammation.
🔗 https://bit.ly/47Ny4sD
August 28, 2025 at 4:22 PM
Important insights this #NationalPsoriasisMonth.
🧪 Even with long-term anti-TNF (infliximab) treatment, patients with psoriasis & psoriatic arthritis show immune cell shifts, suggesting ongoing systemic inflammation.
🔗 https://bit.ly/47Ny4sD
🧪 Even with long-term anti-TNF (infliximab) treatment, patients with psoriasis & psoriatic arthritis show immune cell shifts, suggesting ongoing systemic inflammation.
🔗 https://bit.ly/47Ny4sD
IVIG therapy for ITP comes with heavy dose requirements.
A novel Fc-engineered anti-haptoglobin mAb matches IVIG efficacy in primates, at a fraction of the dose.
🔗 https://bit.ly/4mN8dWJ
A novel Fc-engineered anti-haptoglobin mAb matches IVIG efficacy in primates, at a fraction of the dose.
🔗 https://bit.ly/4mN8dWJ
August 22, 2025 at 5:34 PM
IVIG therapy for ITP comes with heavy dose requirements.
A novel Fc-engineered anti-haptoglobin mAb matches IVIG efficacy in primates, at a fraction of the dose.
🔗 https://bit.ly/4mN8dWJ
A novel Fc-engineered anti-haptoglobin mAb matches IVIG efficacy in primates, at a fraction of the dose.
🔗 https://bit.ly/4mN8dWJ