Lightnews — Scholar-powered news

Reposted by Vanesa Cepas López

Helena Cocheme @cochemelab.bsky.social · 29d

🚨New paper published today on cancer bugs and drugs!🚨

“Chemotherapy modulation by a cancer-associated microbiota metabolite”

Congrats to the Cabreiro lab on this exciting study!
#Cancer #Microbiome #Metabolism #Chemotherapy
#MRC_LMS #ImperialCollege #CECAD_Cologne

www.cell.com/cell-systems...

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Vanesa Cepas López @cepaslopez.bsky.social · Sep 1

The @sfrre-ecr.bsky.social webinar series is back! You can't miss tomorrow's talks by @avdar66.bsky.social and Thibaut Vignane for some exciting insights about Redox Regulation in Cellular Aggregates 🚀

SFRR-E_ ECRs @sfrre-ecr.bsky.social · Sep 1

🎬 WE’RE BACK with the 4th round of ECR webinars! 🚀

Join us tomorrow, September 2nd for our season opener:

"Redox regulation in cellular aggregates"
🎤 Speakers: Avilien Dard, PhD & Thibaut Vignane, PhD

#SFRRIWebinars #ECRVoices #RedoxResearch #WeAreSFRR #ScienceCommunity #LifelongLearning

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Carlos Henriquez-Olguin @musclebiology.bsky.social · Aug 28

🚀New preprint w/ @roberto_amv: We used chemogenetics to precisely control mitochondrial H2O2 in skeletal muscle in vivo. This exposes a dose-dependent sequence: translation suppression → proteolysis → denervation-like → degeneration @tejensen23 www.biorxiv.org/content/10.1...

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Nature Cell Biology @natcellbio.nature.com · Aug 27

🍹Interested in #DevBio and #metabolism ? This Review discusses the relationship between metabolism and embryogenesis!
👉https://rdcu.be/eCHvJ

bit.ly/4oVnB4t

Metabolic regulation of key developmental events during mammalian embryogenesis - Nature Cell Biology

This Review discusses the intricate relationship between metabolism and embryogenesis, highlighting the orchestration of key developmental processes by metabolites and signalling molecules that provid...

bit.ly

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Julia Vorhauser @juliavorhauser.bsky.social · Aug 26

I am very happy to share that my PhD work in the Mansfeld lab (www.mansfeldlab.com) was published yesterday! 🎉 In this study, we characterized a novel redox switch on p21 that regulates proliferation: www.cell.com/molecular-ce...
Huge thanks to everyone involved for making this possible 🙏@icr.ac.uk

A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision

ROS oxidize cell cycle proteins and regulate cell proliferation. Vorhauser et al. show that oxidation of the cyclin-dependent kinase (CDK) inhibitor p21 at cysteine 41 (C41) during the G2 phase contro...

www.cell.com

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Vanesa Cepas López @cepaslopez.bsky.social · Aug 4

If you’re looking for a wonderful postdoc experience plus exciting project, this is the place!

Pedro Friedmann Angeli @angelifriedmann.bsky.social · Aug 4

A new postdoc position in our group will open early next year — looking for candidates with a proven track record & relevant experience.

If #CRISPRscreens, #syntheticlethality, #smallmolecules & #celldeath excite you, let’s talk! DMs welcome.

pls share 🙏

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Vanesa Cepas López @cepaslopez.bsky.social · Jul 14

This is great news! Congratulations Pedro! 🎉🎉

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Alicia Kowaltowski @aliciakowaltowski.bsky.social · Jul 8

Save the dates!

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Ché Pillay @chepillay.bsky.social · Jun 30

Happy to share our review paper, "Emerging Trends for the Regulation of Thiol-Based RedoxTranscription Factor Pathways" doi.org/10.1021/acs.... It was fun learning about the really cool science being undertaken by some excellent labs. Thanks, ACS Biochemistry, for the invite.

Emerging Trends for the Regulation of Thiol-Based Redox Transcription Factor Pathways

Thiol-based redox transcription factor pathways play central roles in the cellular response to peroxide stress. We review the bacterial OxyR, yeast AP-1 and mammalian NRF2/Keap1 systems and the princi...

doi.org

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SFRR-E_ ECRs @sfrre-ecr.bsky.social · Jun 29

Don't miss it !

🧪 The 2nd FEBS Redox Medicine Workshop will explore how the exposome—diet, chemicals, microbes & more—modulates redox regulation in health & disease. From tools to therapies, talks span redox in metabolism, epigenetics, transcription, cell death & beyond.

#Redox #Exposome #FEBS

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Helena Cocheme @cochemelab.bsky.social · Jun 27

🎉Excited to share our latest paper, published in Nature Communications!🎉

"Enhancing autophagy by redox regulation extends lifespan in Drosophila"

#redox #metabolism #ageing #Drosophila

@natcomms.nature.com @mrc-lms.bsky.social

doi.org/10.1038/s414...

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications

Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...

doi.org

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Vanesa Cepas López @cepaslopez.bsky.social · Jun 24

🎉 Exciting news! I’ve been awarded an ECR seed grant from SFRR-E! It supports early career researchers in launching new projects and generating preliminary data for future grant applications. Grateful for the support and looking forward to getting started!
🔗 www.sfrr-europe.org/index.php/aw...

ECR FELLOWSHIP AWARDEES

www.sfrr-europe.org

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Pedro Friedmann Angeli @angelifriedmann.bsky.social · Jun 19

Organelle conversations drive ferroptosis -

news and views on a recent study by @mariamls.bsky.social and colleagues

www.nature.com/articles/s41...

Organelle conversations drive ferroptosis - Nature Cell Biology

Ferroptosis begins with phospholipid peroxidation, leading to membrane damage rupture and cell death. Although research has surged, the intracellular site for ferroptosis initiation remains uncertain....

www.nature.com

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Manuel Collado @manuel-collado.bsky.social · Jun 4

Want to apply for a Marie Skłodowska-Curie Fellowships to work with us? Apply: cimus.usc.gal/jobs/marie-s...

Marie Skłodowska-Curie Fellowships: Call for Expressions of Interest 2025 | CiMUS

Marie Skłodowska-Curie Fellowships: Call for Expressions of Interest 2025

cimus.usc.gal

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Pedro Friedmann Angeli @angelifriedmann.bsky.social · May 29

New review together with
@k-hadian.bsky.social group-

Have fun reading!
#ferroptosis #nutrition #celldeath

www.sciencedirect.com/science/arti...

The metabolic code of ferroptosis: nutritional regulators of cell death

Ferroptosis is a distinctive form of regulated cell death driven by iron-dependent phospholipid peroxidation. Its initiation and suppression are finel…

www.sciencedirect.com

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Andrea Morandi @andreamorandi.bsky.social · May 24

.🧬We looked for a CD44:SLC1A2 fusion in breast cancer. The data said no. Instead of shelving it, we published.
📢 Now out in @SpringerNature MCB: link.springer.com/article/10.1...
Negative results matter. Transparency matters. Proud of this one 🥳! #OpenScience

CD44 and SLC1A2 are commonly regulated but do not form a fusion transcript in ER+ breast cancer - Molecular and Cellular Biochemistry

Endocrine therapy (ET) is essential for managing ER+ HER2− breast cancer; however, resistance remains a significant clinical challenge. This study investigated whether CD44-SLC1A2 gene fusions, report...

link.springer.com

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Vanesa Cepas López @cepaslopez.bsky.social · May 21

🚨🚨The call for the new edition of the Mentoring Program is open. You can apply as a mentor or mentee through the SFRR-E intranet, it only takes 10 minutes!

SFRR-E_ ECRs @sfrre-ecr.bsky.social · May 21

Say hello to Tim, Pariki, Timo, and Vanesa.

👥 Mentoring Program — Personalized mentor–mentee pairs to support your career journey.
📝 Editorial Mentoring Program — Learn how to peer-review scientific papers with guidance from senior researchers.

Interested? Contact us [email protected]

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Dana Reichmann @danareichmann.bsky.social · May 19

The @EMBO workshop #EMBOthiolSwitches is coming up soon, join us in beautiful Sant Feliu de Guíxols, Spain, 13–18 September 2025!
We have a fantastic speaker lineup, with a few spots still open for short talks. Abstract deadline extended to 31 May 2025.

meetings.embo.org/event/25-thi...

Thiol-based redox switches: From chemistry to physiology and pathology

Redox reactions have been essential for the emergence of life on Earth, and diverse strategies have evolved for responding to various cellular redox species. These mechanisms are still of vital impor…

meetings.embo.org

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Leticia Prates Roma @prates-roma.bsky.social · May 12

New Professor position at Saarland University for Cell Physiology!

Morgan Lab @morganlab-saarland.bsky.social · Apr 30

We are looking for a new colleague in the biology department at Saarland University!

We are looking for excellent Cell Biologists / Cell Physiologists for a W2 tenure track W3 professorship in 'Dynamics of Biological Systems'.

Please share!

jobs.zeit.de/jobs/w2-prof...

W2 Professorship (with tenure track to W3) in the Dynamics of Biological Systems (m/f/x) - Universität des Saarlandes

Universität des Saarlandes bietet Stelle als W2 Professorship (with tenure track to W3) in the Dynamics of Biological Systems (m/f/x) in Saarbrücken - jetzt bewerben!

jobs.zeit.de

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RiemerLab @ UoCologne @riemerlab.bsky.social · May 12

A new tool from our lab :-). Together with the Brachvogel, Bogeski and Mielenz labs. We developed a genetically encoded sensor to monitor activity of the dipeptidases DPP8 and DPP9 in cells allowing us to ask fundamental questions about their spatiotemporal regulation. DOI: 10.26508/lsa.202403076

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James Olzmann @olzmannlab.bsky.social · May 7

Excited to see our N&V w/ @mikelangelipid.bsky.social published in Nature, highlighting new work from Raphael Rodriguez and team. A heterofunctional molecule that activates lysosomal iron triggers lipid peroxidation and ferroptosis in therapy-resistant cancer cells. www.nature.com/articles/d41...

Lipid-degrading small molecule kills cancer cells by ferroptosis

A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell death might offer a way to tackle treatment-resistant cancer.

www.nature.com

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Plant Energy Biology Lab @schwarzlanderlab.bsky.social · Apr 17

Monitoring subcellular NADP redox state with NAPstar biosensors @riemerlab.bsky.social @morganlab-saarland.bsky.social
@jan-oleniemeier.bsky.social

www.sciencedirect.com/science/arti...

Monitoring subcellular NADP redox state with NAPstar biosensors

www.sciencedirect.com

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Vanesa Cepas López @cepaslopez.bsky.social · Mar 31

📢 Exciting Webinar Alert!

Join us tomorrow, April 1st, at 15:00 CET for an unmissable webinar on chaperones in redox biology, hosted by @sfrre-ecr.bsky.social! We’re thrilled to welcome two fantastic speakers: @ulrichlab.bsky.social and @rsutandy.bsky.social.
See you there!

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Paraskevi Kritsiligkou @parikki.bsky.social · Mar 28

I am delighted to be in London next month for the UK Redox Network! If you would like to join us, there is still time to register forms.office.com/e/8Zt9Kq2dag! I am very thankful for the opportunity to talk about my work (two years in a row)! Hopefully I wont be broken this time, just jet lagged...

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Laia Josa-Culleré @laiajosacullere.bsky.social · Mar 28

📢 We are seeking candidates to apply for the PhD fellowship FI-STEP from AGAUR with us!
💊 You will work on #MedChem projects for cancer, combining organic chemistry and some biology.
🌍 Due to the call's requirements, you must have European citizenship.
Get in touch!

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