Lightnews — Scholar-powered news

Reposted by Corey Horien

TK (Takashi DY) Kozai @bioniclab.bsky.social · 19h

NIH cuts save $9-10B short-term, but they’re killing 202K jobs & $46B in red-state economies (TX, FL, OH). $8T healthcare disaster loom, no cancer/Alzheimer’s cures, pricier drugs. Scientists fleeing to China? Bad deal. Fight for NIH!
www.the-scientist.com/nih-leadersh...

#AmericaFirst

NIH Leadership Is Failing Early Career Researchers

Halted training programs, funding chaos, and hiring freezes jeopardize advancement options for early career researchers.

www.the-scientist.com

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Reposted by Corey Horien

Kangjoo Lee @kangjoolee.bsky.social · 2d

🚀 Excited to share our new review article published in Biological Psychiatry (In Press)! doi.org/10.1016/j.bi...
💡 ❓ I’d love to hear your thoughts, feedback, and ideas on how we can push the boundaries of psychiatric research together and make real clinical impact.

Redirecting

doi.org

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Corey Horien @coreyhorien.bsky.social · 1d

www.nytimes.com/2025/10/09/s...

Nobel Prizes This Year Offer Three Cheers for Slow Science

www.nytimes.com

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Reposted by Corey Horien

David Ho @davidho.bsky.social · 2d

Hey US scientists, the NY Times wants to hear from you if you've had your funding cut. 🌊🧪

Has Your Scientific Work Been Cut? We Want to Hear.

www.nytimes.com

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Reposted by Corey Horien

PennMedCSO @pennmedcso.bsky.social · 2d

Reproducible Brain Charts: Mapping brain development & mental health ft. @goliashf.bsky.social, T. Moore, T. Salo, M. Calkins, R. Gur, R. Gur, @cieslakmatt.bsky.social, @ted-satterthwaite.bsky.social, C. Davatzikos & R. Shinohara (@dbei-upenn.bsky.social) www.sciencedirect.com/science/arti...

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Reposted by Corey Horien

Carl Zimmer @carlzimmer.com · 2d

Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE

nyti.ms

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Reposted by Corey Horien

Benjamin Kay @benjaminkay.bsky.social · 3d

Check out some compelling and timely work by @nasiametoki.bsky.social on sex vs gender differences in the developing adolescent brain!

nasiametoki.bsky.social @nasiametoki.bsky.social · 4d

Is resting-state functional connectivity (rsFC), cortical thickness (CT), or cortical volume more effective at capturing sex and gender differences in the brains of preadolescents?

Check out our new article (doi.org/10.1016/j.dc...) now out in Developmental Cognitive Neuroscience.

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Reposted by Corey Horien

Todd Constable @toddc.bsky.social · 4d

Strong work AJ and team - good to see this come together!

AJ Simon @ayejaysimon.bsky.social · 5d

New preprint alert!

We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.

Transdiagnostic connectome-based predictive modeling of many behavioral phenotypes reveals brain network mediators of clinical-cognitive relationships

Connectome-based predictive modeling (CPM) applied to functional MRI connectivity data can identify brain networks that vary with behavioral measures across subjects. The prediction strength also prov...

www.biorxiv.org

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Reposted by Corey Horien

AJ Simon @ayejaysimon.bsky.social · 5d

New preprint alert!

We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.

Transdiagnostic connectome-based predictive modeling of many behavioral phenotypes reveals brain network mediators of clinical-cognitive relationships

Connectome-based predictive modeling (CPM) applied to functional MRI connectivity data can identify brain networks that vary with behavioral measures across subjects. The prediction strength also prov...

www.biorxiv.org

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Reposted by Corey Horien

Drug Monkey @drugmonkey.bsky.social · 8d

More NIH chaos.

NICHD, NIMHD and NIAID Directors are all dismissed.

Princess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 8d

Jeanne Marrazzo, director of NIAID, claimed that the Trump Administration’s actions
endangered research subjects, defied court orders & undermined vaccine research.

Earlier, Kennedy fired Susan Monarez of the CDC.

Resisting unethical policies costs you.

🧪🎁🔗
www.nytimes.com/2025/10/02/h...

Kennedy Fires N.I.H. Scientist Who Filed Whistle-Blower Complaint

www.nytimes.com

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Reposted by Corey Horien

Boris Bernhardt @borismontreal.bsky.social · 9d

🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus

Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)

Led by @jordandekraker.bsky.social

docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...

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Reposted by Corey Horien

Corey Horien @coreyhorien.bsky.social · 9d

Really proud to share this w/ @francimandi.bsky.social from the Lake lab: we applied fingerprinting in a simultaneous wide-field fluorescence Ca2+ imaging and BOLD-fMRI dataset in mice!

w/ @toddc.bsky.social @mallarchak.bsky.social @richardfbetzel.bsky.social et al.

www.nature.com/articles/s42...

Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI - Communications Biology

Using simultaneously acquired wide-field fluorescence calcium imaging and BOLD-fMRI, subject-specific signatures are observable in the mouse connectome, with stronger individual specific patterns evident in the calcium data.

www.nature.com

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Reposted by Corey Horien

Mallar Chakravarty @mallarchak.bsky.social · 9d

Excited to share our new publication on the impact of #THC exposure during gestation on brain development. This stunning work, led by Lani Cupo, describes several years of datas collection and examines brain development and maturation using MRI and behaviour

www.nature.com/articles/s41...

👇🏾👇🏾👇🏾👇🏾

Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study - Molecular Psychiatry

Molecular Psychiatry - Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study

www.nature.com

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Reposted by Corey Horien

Zachary H. Gursky @zachary-gursky.bsky.social · Sep 4

🧵1/3 Excited for my recent 🧪research out at @jclinical-invest.bsky.social! At @yaleschoolofmed.bsky.social Anesthesiology, we manipulated coupling between brain (cerebrospinal fluid🧠💧[CSF]) and cervical lymph vessels. We saw age-based drainage changes, ⬆️📈neuroinflammation and ⬇️📉brain homeostasis.

Journal of Clinical Investigation @jci.org · Sep 3

How does impaired lymphatic drainage affect cerebral homeostasis?

Helene Benveniste & team use dynamic CE-MRI and computational fluid dynamics in a rat model of mechanical stress to deep cervical lymph nodes, revealing the brain’s adaptive response.

buff.ly/k9sGQoQ

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Corey Horien @coreyhorien.bsky.social · 9d

Really proud to share this w/ @francimandi.bsky.social from the Lake lab: we applied fingerprinting in a simultaneous wide-field fluorescence Ca2+ imaging and BOLD-fMRI dataset in mice!

w/ @toddc.bsky.social @mallarchak.bsky.social @richardfbetzel.bsky.social et al.

www.nature.com/articles/s42...

Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI - Communications Biology

Using simultaneously acquired wide-field fluorescence calcium imaging and BOLD-fMRI, subject-specific signatures are observable in the mouse connectome, with stronger individual specific patterns evident in the calcium data.

www.nature.com

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Reposted by Corey Horien

Biological Psychiatry @biologicalpsych.bsky.social · 9d

In this review, @lucinauddin.bsky.social and Hugh Garavan examine how task and resting-state fMRI can reveal brain-behavior relationships in youth, highlighting current controversies and challenges, outlining solutions, and proposing future directions in developmental neuroscience research.

Task and resting state fMRI modelling of brain-behavior relationships in developmental cohorts

Functional magnetic resonance imaging (fMRI) data are often used to inform individual differences in cognitive, behavioral, and psychiatric phenotypes. These so-called “brain-behavior” association stu...

www.biologicalpsychiatryjournal.com

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Reposted by Corey Horien

Arielle Keller @ariellekeller.bsky.social · 10d

Your brain is unique! 🧠 If you're curious to see more individual-level fMRI at #CNS2026, please consider voting for our symposium "Not Your Average Brain" by end of day today! 🍁

#neuroskyence #cogpsyc #cogsci #PsychSciSky #neuroimaging @cogneuronews.bsky.social

Caterina Gratton @caterinagratton.bsky.social · 11d

Are you a @cogneuronews.bsky.social member?
Consider voting for our symposium at #CNS2026:
Not Your Average Brain: Individual-Level fMRI as a Paradigm Shift for Cognitive Neuroscience
Led by @jingnandu.bsky.social & A Zamani w/ C Lynch
Vote: www.cogneurosociety.org/account-login/
By: 11:59pm Oct. 1

CNS Account Login - Cognitive Neuroscience Society

March 7 – 10, 2026 Submit a Symposium Submit a Poster Latest from Twitter

www.cogneurosociety.org

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Reposted by Corey Horien

Max Kozlov @maxkozlov.bsky.social · 11d

From an NIH source:

"The fact that it’s 8am on the day of a likely shutdown, and NIH personnel have received not one word about it from our leaders, from HHS, or higher, is gobsmacking.

Normally we receive shutdown preparations emails starting days in advance. Absolute silence except at IC level."

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Reposted by Corey Horien

Benjamin Kay @benjaminkay.bsky.social · 11d

Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...

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Reposted by Corey Horien

Max Kozlov @maxkozlov.bsky.social · 11d

Staff members at the NIH seem to have done the impossible: spend the agency's $48 billion budget.

“Everyone has been rallying together to clean up the mess, but it’s a mess that did not need to be made,” an NIH program officer told me.

www.nature.com/articles/d41...

NIH races to spend its 2025 grant money — but fewer projects win funding

Despite political obstacles, officials are on track to disburse all of the research funds allocated to US biomedical behemoth.

www.nature.com

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Reposted by Corey Horien

Avram Holmes @avramholmes.bsky.social · 11d

Another wonderful paper from @annierhcheng.bsky.social and @yiplab.bsky.social! Impulsivity, negative affect, and risky alcohol use in youth.

Sarah Yip @yiplab.bsky.social · 14d

New paper from @annierhcheng.bsky.social

using data from IMAGEN and ABCD she identifies distinct signatures of impulsivity and negative affect in youth that uniquely overlap with a neuromarker of risky alcohol use

#development #equifinality #abcd #connectome

www.nature.com/articles/s41...

Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth - Molecular Psychiatry

Molecular Psychiatry - Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth

www.nature.com

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Reposted by Corey Horien

The Transmitter @thetransmitter.bsky.social · 11d

“It’s hard to know if I should close down my existing projects and/or redouble my efforts writing new grant applications,” Joshua Jacobs, associate professor of biomedical engineering at Columbia University, told @thetransmitter.bsky.social.

By Natalia Mesa

www.thetransmitter.org/funding/nih-...

NIH awarded 37 percent fewer neuroscience-related grants in 2025 than in past years

But the agency has spent nearly its entire budget for this fiscal year, which ends tomorrow.

www.thetransmitter.org

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Corey Horien @coreyhorien.bsky.social · 12d

Awesome stuff here from @annierhcheng.bsky.social g.bsky.social and @yiplab.bsky.social using predictive modelling of fMRI connectivity data to find markers of impulsivity and negative affect in IMAGEN and ABCD

w/ @toddc.bsky.social, @baderchaarani.bsky.social et al.

Sarah Yip @yiplab.bsky.social · 14d

New paper from @annierhcheng.bsky.social

using data from IMAGEN and ABCD she identifies distinct signatures of impulsivity and negative affect in youth that uniquely overlap with a neuromarker of risky alcohol use

#development #equifinality #abcd #connectome

www.nature.com/articles/s41...

Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth - Molecular Psychiatry

Molecular Psychiatry - Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth

www.nature.com

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Reposted by Corey Horien

Marc L Seal @parkvillegeek.bsky.social · 12d

A neuroimaging database combining movie-watching, eye-tracking, sensorimotor mapping, and cognitive tasks | bioRxiv www.biorxiv.org/content/10.1...

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Reposted by Corey Horien

Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 14d

Hearing from someone in NIH program:

“Our final Task Order for $6.2M went out today. Every obstacle DOGE put up to keep us from funding new TOs and extending others was overcome. My fired contract officers were rehired. It was a lot of work, but we did it.
For now.”

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