Biological Psychiatry
@biologicalpsych.bsky.social
Official account for the Biological Psychiatry family of journals.
Publishing cutting-edge research in psychiatric neuroscience, cognitive neuroimaging, and global open science.
Publishing cutting-edge research in psychiatric neuroscience, cognitive neuroimaging, and global open science.
Paper mills 🏭, citation cartels 🤝, coercive citation practices ⛓️, fake reviewers 🎭, and AI-generated papers 🤖 challenge scientific integrity.
Learn more about what we're doing in our journals to address this.
Learn more about what we're doing in our journals to address this.
Biological Psychiatry: Addressing new challenges to scientific integrity including paper mills, citation cartels, coercive citation practices, fake reviewers, and AI-generated papers
Preserving the scientific integrity of papers published in the family of Biological Psychiatry journals has never been more important and more challenging. Real papers from real authors based on real…
www.biologicalpsychiatryjournal.com
December 3, 2025 at 1:50 PM
Paper mills 🏭, citation cartels 🤝, coercive citation practices ⛓️, fake reviewers 🎭, and AI-generated papers 🤖 challenge scientific integrity.
Learn more about what we're doing in our journals to address this.
Learn more about what we're doing in our journals to address this.
📣 Our latest Special Issue is now out! 📣
Exploring Sleep Alterations in Severe Mental Disorders: Converging Evidence From Basic, Translational, and Clinical Research was edited by Armando D’Agostino, Anna Castelnovo, Giulio Tononi, and Fabio Ferrarelli.
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Learn more about what's in the issue ⬇️
Exploring Sleep Alterations in Severe Mental Disorders: Converging Evidence From Basic, Translational, and Clinical Research was edited by Armando D’Agostino, Anna Castelnovo, Giulio Tononi, and Fabio Ferrarelli.
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Learn more about what's in the issue ⬇️
Current Issue Table of Contents: Biological Psychiatry
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December 1, 2025 at 11:30 AM
📣 Our latest Special Issue is now out! 📣
Exploring Sleep Alterations in Severe Mental Disorders: Converging Evidence From Basic, Translational, and Clinical Research was edited by Armando D’Agostino, Anna Castelnovo, Giulio Tononi, and Fabio Ferrarelli.
💤 🧠 🧬
Learn more about what's in the issue ⬇️
Exploring Sleep Alterations in Severe Mental Disorders: Converging Evidence From Basic, Translational, and Clinical Research was edited by Armando D’Agostino, Anna Castelnovo, Giulio Tononi, and Fabio Ferrarelli.
💤 🧠 🧬
Learn more about what's in the issue ⬇️
How are advanced PET imaging biomarkers 🔬 enhancing our ability to study neuroimmune dynamics 🧠🛡️ in psychiatric illness 😔 to refine diagnostics 🩺 and discover new therapies ✨?
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Imaging Neuroimmune Dysfunction: From TSPO to Emerging PET Targets
Dysregulation of the neuroimmune system is increasingly recognized as a key contributor to psychiatric illness, yet its complexity and the limitations of current methodologies have hindered a clear…
www.biologicalpsychiatryjournal.com
November 28, 2025 at 1:01 PM
How are advanced PET imaging biomarkers 🔬 enhancing our ability to study neuroimmune dynamics 🧠🛡️ in psychiatric illness 😔 to refine diagnostics 🩺 and discover new therapies ✨?
Find out here 👇
Find out here 👇
What role do the pituitary adenylate cyclase activating polypeptide 🧬 connections play in the pathway from the bed nucleus of the stria terminalis to the dorsal medial habenula 🧠➡️🧠 to mediate depression-like behaviors 😔 after chronic stress?
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BNST PACAP signaling in the dorsal medial habenula mediates depression- related behavioral responses after chronic stress
Hallmark behaviors associated with depression-related disorders include reduction in reward responsivity and increased despair. However, the neurocircuits and mechanisms underlying reward responding…
www.biologicalpsychiatryjournal.com
November 27, 2025 at 4:02 PM
What role do the pituitary adenylate cyclase activating polypeptide 🧬 connections play in the pathway from the bed nucleus of the stria terminalis to the dorsal medial habenula 🧠➡️🧠 to mediate depression-like behaviors 😔 after chronic stress?
Learn more here 👇
Learn more here 👇
What have clinical trials 🧪 revealed about optimizing 📈 the use of immunomodulatory drugs 💊 for psychiatric disorders 🧠?
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Lessons from clinical trials of immunomodulatory drugs in psychiatric disorders
Immune dysregulation has been implicated in the pathophysiology of psychiatric disorders, with peripheral inflammatory markers correlating with symptom severity, treatment refractoriness, and neural…
www.biologicalpsychiatryjournal.com
November 27, 2025 at 1:02 PM
What have clinical trials 🧪 revealed about optimizing 📈 the use of immunomodulatory drugs 💊 for psychiatric disorders 🧠?
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Can studying white matter network 🕸️ disruption in Multiple Sclerosis advance our understanding of depression's 😔 pathophysiology?
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Depression as a disease of white matter network disruption: Learning from Multiple Sclerosis
Depression is a common and debilitating psychiatric disorder that is associated with substantial morbidity and mortality. For nearly 40 years, scientists have attempted to localize depression in the…
www.biologicalpsychiatryjournal.com
November 26, 2025 at 4:03 PM
Can studying white matter network 🕸️ disruption in Multiple Sclerosis advance our understanding of depression's 😔 pathophysiology?
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How are methamphetamine-induced 💊 changes ↔️ in functional brain connectivity patterns 🧠🔗 linked to attention 🎯 and arousal ⚡?
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Methamphetamine modulates functional connectivity signatures of sustained attention and arousal
Between-subjects studies suggest that psychostimulants can shift whole-brain functional connectivity toward patterns linked to heightened sustained attention. In this study, we examined how a single…
www.biologicalpsychiatrycnni.org
November 26, 2025 at 1:01 PM
How are methamphetamine-induced 💊 changes ↔️ in functional brain connectivity patterns 🧠🔗 linked to attention 🎯 and arousal ⚡?
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How do altered brain network 🧠 co-activation 🤝 patterns relate to clinical symptoms 🏥 in major depressive disorder 😞 ?
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Synergistic Co-Activation Probabilities of Large-Scale Resting State Networks in Major Depressive Disorder
Major depressive disorder (MDD) involves subtle, distributed alterations across multiple large-scale resting-state brain networks (RSNs), highlighting the need for integrative approaches to uncover…
www.biologicalpsychiatrycnni.org
November 25, 2025 at 4:01 PM
How do altered brain network 🧠 co-activation 🤝 patterns relate to clinical symptoms 🏥 in major depressive disorder 😞 ?
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How do mood and psychotic disorders differentially affect effort-cost decision-making 💪💰 and how is that related to subjective value representation ⭐?
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Understanding Effort-Cost Decision-Making Mechanisms in Mood and Psychotic Disorders: A Computational Modeling Approach Across Physical and Cognitive Effort Paradigms
Effort-cost decision-making (ECDM) is a core component of motivational deficits across diagnostic boundaries, yet mechanisms underlying ECDM deficits are not yet fully understood. Importantly,…
www.biologicalpsychiatrycnni.org
November 25, 2025 at 1:00 PM
How do mood and psychotic disorders differentially affect effort-cost decision-making 💪💰 and how is that related to subjective value representation ⭐?
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Can Glucagon-Like Peptide-1 Receptor Agonists 💊 reduce 📉 alcohol consumption 🍷?
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Glucagon-Like Peptide-1 Receptor Agonists and Alcohol Use: A Real-Word Observational Study in a Large, Integrated Healthcare System
Growing research suggests that glucagon-like peptide-1 receptor agonists (GLP-1RAs) reduce alcohol consumption, positioning them as new potential pharmacotherapies for alcohol use disorder. However,…
www.bpsgos.org
November 24, 2025 at 6:34 PM
Can Glucagon-Like Peptide-1 Receptor Agonists 💊 reduce 📉 alcohol consumption 🍷?
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How does stress-induced activation in the oval nucleus of the bed nucleus of the stria terminalis 🧠 establish a pathway to resilience 💪 against chronic stress-induced depression 😩?
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Stress History Modulates CRF Neurons to Establish Resilience
Cumulative stress is a major risk factor for developing major depressive disorder (MDD), yet not everyone experiencing chronic stress develops MDD. In those who do not, it is unclear at what point,…
www.bpsgos.org
November 21, 2025 at 4:01 PM
How does stress-induced activation in the oval nucleus of the bed nucleus of the stria terminalis 🧠 establish a pathway to resilience 💪 against chronic stress-induced depression 😩?
Find out here 👇
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How does chronic stress-induced immune dysfunction 🔥 in the brain 🧠 and periphery contribute to psychiatric behavioral changes?
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Immunity in rodent models of stress
Chronic stress is a major risk factor for several psychiatric disorders, including major depressive disorder and posttraumatic stress disorder. This review synthesizes rodent-based findings showing…
www.biologicalpsychiatryjournal.com
November 21, 2025 at 1:01 PM
How does chronic stress-induced immune dysfunction 🔥 in the brain 🧠 and periphery contribute to psychiatric behavioral changes?
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How do stress 😩 and schizophrenia 🧠 alter the timing ⏰ of neurovascular coupling 🩸 across brain networks 🕸️?
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Noncanonical EEG-BOLD coupling by default and in schizophrenia
Neuroimaging methods rely on models of neurovascular coupling that assume hemodynamic responses are canonical; evolving seconds after changes in neural activity. However, emerging evidence reveals…
www.biologicalpsychiatrycnni.org
November 20, 2025 at 4:02 PM
How do stress 😩 and schizophrenia 🧠 alter the timing ⏰ of neurovascular coupling 🩸 across brain networks 🕸️?
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How can the visual system 👁️ be used to guide psychosis treatment 🧠 and assess treatment response 📈?
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Vision and Psychosis: A Clinical Translational Perspective
The visual system, as one of the most well-understood components of the central nervous system, offers a unique framework for understanding mechanistic aspects of psychosis. This review explores the…
www.biologicalpsychiatryjournal.com
November 20, 2025 at 1:01 PM
How can the visual system 👁️ be used to guide psychosis treatment 🧠 and assess treatment response 📈?
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How do orexins 🧪 affect stress states 😩 and behavioral responses 🧠?
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Functional Plasticity of Orexin/Hypocretin Neurons Balances Stress States
Orexin/hypocretin (Orx) peptides critically contribute to stress and arousal circuits’ flexibility and equilibrium. New discoveries highlight plasticity of orexin neurons themselves, as well as…
www.biologicalpsychiatryjournal.com
November 19, 2025 at 4:01 PM
How do orexins 🧪 affect stress states 😩 and behavioral responses 🧠?
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Our November issue of Biological Psychiatry: Global Open Science is live!
Current Issue Table of Contents: Biological Psychiatry: Global Open Science
www.bpsgos.org
November 19, 2025 at 1:02 PM
Our November issue of Biological Psychiatry: Global Open Science is live!
How do striatal levels of glutamate & GABA 🧪 associate 🔗 with dopaminergic function ⚡ in antipsychotic-naive first-episode psychosis 🧠?
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The relationship between neuromelanin, glutamate, and GABA in first-episode psychosis: A multimodal magnetic resonance imaging study
In vivo neuroimaging studies documenting the relationship between dopamine and γ-aminobutyric acid (GABA) or glutamate in schizophrenia are scarce and frequently involve patients in chronic phases of…
www.biologicalpsychiatrycnni.org
November 18, 2025 at 1:02 PM
How do striatal levels of glutamate & GABA 🧪 associate 🔗 with dopaminergic function ⚡ in antipsychotic-naive first-episode psychosis 🧠?
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Find out here ⬇️
Reposted by Biological Psychiatry
Join us in congratulating Paul M. Thompson, PhD, a leader in brain imaging and associate director of USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), who has been selected as the recipient of the 2025 Gold Medal Award from the Society of Biological Psychiatry (SOBP).
Top USC researcher awarded Gold Medal by Society of Biological Psychiatry
Related News Double Victory: Residency Classmates Turned USC Faculty Achieve NIH Funding Success March 21, 2024 From electrical engineering to the inner ear: how Radha Kalluri, PhD, uses the physical ...
keck.usc.edu
September 29, 2025 at 4:43 PM
Join us in congratulating Paul M. Thompson, PhD, a leader in brain imaging and associate director of USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), who has been selected as the recipient of the 2025 Gold Medal Award from the Society of Biological Psychiatry (SOBP).
Reposted by Biological Psychiatry
We're looking forward to #SOBP2026!
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
October 16, 2025 at 2:22 PM
We're looking forward to #SOBP2026!
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
Reposted by Biological Psychiatry
Longitudinal associations of structural and functional brain connectivity with dimensions of psychopathology in adolescence. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
doi.org/10.1016/j.bp...
doi.org/10.1016/j.bp...
Redirecting
doi.org
October 1, 2025 at 1:15 AM
Longitudinal associations of structural and functional brain connectivity with dimensions of psychopathology in adolescence. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
doi.org/10.1016/j.bp...
doi.org/10.1016/j.bp...
How does stimulation ⚡ of the frontal cortex 🧠 for anxious depression differentially affect executive function/attention 💡 and threat sensitivity ⚠️?
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Frontal cortex stimulation modulates attentional circuits and increases anxiety potentiated startle in anxious depression
Major depressive disorder (MDD) with comorbid anxiety presents significant treatment challenges, with high relapse rates and suboptimal outcomes. Transcranial direct current stimulation (tDCS) offers…
www.biologicalpsychiatrycnni.org
November 17, 2025 at 1:01 PM
How does stimulation ⚡ of the frontal cortex 🧠 for anxious depression differentially affect executive function/attention 💡 and threat sensitivity ⚠️?
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How do dissociative states affect brain state dynamics 🧠, and do these effects vary if pharmacologically induced 💊 or due to a clinical condition 🏥?
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Brain State Dynamics in Ketamine-Induced Dissociation Resemble Those in PTSD
Dissociation, an altered state of consciousness in which individuals feel detached from their body, environment, and sense of self, is a common feature of Post-Traumatic Stress Disorder (PTSD).…
www.bpsgos.org
November 16, 2025 at 1:00 PM
How do dissociative states affect brain state dynamics 🧠, and do these effects vary if pharmacologically induced 💊 or due to a clinical condition 🏥?
Learn more here ⬇️
Learn more here ⬇️
The latest Biological Psychiatry issue, focused on Social Stress and Psychological Traumas, is now out!
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November 15, 2025 at 2:01 PM
The latest Biological Psychiatry issue, focused on Social Stress and Psychological Traumas, is now out!
Check it out ⬇️
Check it out ⬇️
Do the associations between irritability 💢 and subcortical volume 🧠 differ between the sexes ♂️♀️ ?
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Sex-Specific Associations of Irritability with Subcortical Brain Volumes
Irritability is transdiagnostic and associated with considerable impairment. The behavioral presentation of irritability may vary with age, sex, and diagnosis. Although inconsistent, clinical…
www.bpsgos.org
November 15, 2025 at 1:00 PM
Do the associations between irritability 💢 and subcortical volume 🧠 differ between the sexes ♂️♀️ ?
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How can we use machine learning and deep learning models 🤖 trained on EEG data 〰️ to diagnose 🩺 dissociative disorders?
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EEG-Based Machine and Deep Learning Approaches for the Diagnosis of Dissociative Disorders: A Comprehensive Review
Dissociative disorders (DDs), including dissociative identity disorder and depersonalization disorder, are complex and often misdiagnosed psychiatric conditions due to their overlapping symptoms with…
www.bpsgos.org
November 14, 2025 at 3:04 PM
How can we use machine learning and deep learning models 🤖 trained on EEG data 〰️ to diagnose 🩺 dissociative disorders?
Find out here 👇
Find out here 👇