Yael David
@davidlabmsk.bsky.social
Proud PI of the David lab @sloan_kettering, NY.
We develop and apply chemical tools towards studying fundamental questions in chromatin biology. Opinions are my own.
https://www.davidlabmsk.com
We develop and apply chemical tools towards studying fundamental questions in chromatin biology. Opinions are my own.
https://www.davidlabmsk.com
Reposted by Yael David
Thrilled to announce the upcoming Center for Epigenetic Research Symposium @mskcancercenter.bsky.social on Nov 17! 🎉 A full day of cutting-edge science featuring stellar external speakers & our outstanding trainees. Registration is now open! Join us in NYC or virtually from anywhere! link⬇️
September 15, 2025 at 4:12 PM
Thrilled to announce the upcoming Center for Epigenetic Research Symposium @mskcancercenter.bsky.social on Nov 17! 🎉 A full day of cutting-edge science featuring stellar external speakers & our outstanding trainees. Registration is now open! Join us in NYC or virtually from anywhere! link⬇️
Thrilled to announce the upcoming Center for Epigenetic Research Symposium @mskcancercenter.bsky.social on Nov 17! 🎉 A full day of cutting-edge science featuring stellar external speakers & our outstanding trainees. Registration is now open! Join us in NYC or virtually from anywhere! link⬇️
September 15, 2025 at 4:12 PM
Thrilled to announce the upcoming Center for Epigenetic Research Symposium @mskcancercenter.bsky.social on Nov 17! 🎉 A full day of cutting-edge science featuring stellar external speakers & our outstanding trainees. Registration is now open! Join us in NYC or virtually from anywhere! link⬇️
Reposted by Yael David
Did not have time to post about this before vacation. Such a joy to have this chat with @davidlabmsk.bsky.social and Nobel Laureate Charles Rice on Yael's amazing work, capitalising on chromatin biology to understand hepatitis. www.nature.com/articles/s41...
Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis - Nature Structural & Molecular Biology
Yael David leads her lab focused on studying the fundamental mechanisms of epigenetic regulation of transcription at Memorial Sloan Kettering Cancer Center, and Charles Rice is the Maurice R. and Cori...
www.nature.com
July 27, 2025 at 7:47 PM
Did not have time to post about this before vacation. Such a joy to have this chat with @davidlabmsk.bsky.social and Nobel Laureate Charles Rice on Yael's amazing work, capitalising on chromatin biology to understand hepatitis. www.nature.com/articles/s41...
A new lab picture is an opportunity to welcome two new postdocs to my awesome group: Kevin Schiefelbein (from @ninahartrampf.bsky.social), who received @snsf.ch & Giuseppe Quarto (from @fukslab.bsky.social) who received @embo.org Fellow! So proud & excited to see the great science you do!
June 27, 2025 at 1:01 PM
A new lab picture is an opportunity to welcome two new postdocs to my awesome group: Kevin Schiefelbein (from @ninahartrampf.bsky.social), who received @snsf.ch & Giuseppe Quarto (from @fukslab.bsky.social) who received @embo.org Fellow! So proud & excited to see the great science you do!
Reposted by Yael David
🚨 New meeting this fall in Brussels! 🚨
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
June 3, 2025 at 11:45 AM
🚨 New meeting this fall in Brussels! 🚨
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
Reposted by Yael David
🧬Thrilled to be sponsoring this meeting, which includes great opportunities for trainees to learn about different career paths. #epigenetics2025 check it out!
🔗 xcellsconferences.com/epigenetics2025
🔗 xcellsconferences.com/epigenetics2025
🚨 New meeting this fall in Brussels! 🚨
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
June 3, 2025 at 12:23 PM
🧬Thrilled to be sponsoring this meeting, which includes great opportunities for trainees to learn about different career paths. #epigenetics2025 check it out!
🔗 xcellsconferences.com/epigenetics2025
🔗 xcellsconferences.com/epigenetics2025
🚨 New meeting this fall in Brussels! 🚨
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
June 3, 2025 at 11:45 AM
🚨 New meeting this fall in Brussels! 🚨
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩
#epigenetics2025
Registration is open!!
@epicypher.bsky.social
xcellsconferences.com/epigenetics2025
OMW back from the Gordon on Cancer Genetics & Epigenetics, reflecting on an incredible week of science, sunshine, & inspiring conversations. Grateful for the chance to connect w/ rising PIs & brilliant trainees-thank you @matlupien.bsky.social & @shenhui1986.bsky.social for a special meeting! 🤩
May 24, 2025 at 2:29 PM
OMW back from the Gordon on Cancer Genetics & Epigenetics, reflecting on an incredible week of science, sunshine, & inspiring conversations. Grateful for the chance to connect w/ rising PIs & brilliant trainees-thank you @matlupien.bsky.social & @shenhui1986.bsky.social for a special meeting! 🤩
Packing my favorite histone marks and heading to @stanford.edu @stanfordimmunology.bsky.social ! Thanks to Priscilla Yang for the invite! Come for the science, stay for the chromatin drama 🤩
May 13, 2025 at 2:18 PM
Packing my favorite histone marks and heading to @stanford.edu @stanfordimmunology.bsky.social ! Thanks to Priscilla Yang for the invite! Come for the science, stay for the chromatin drama 🤩
Reposted by Yael David
Excited for this summer’s NYC Chromatin Club!
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
May 5, 2025 at 3:01 AM
Excited for this summer’s NYC Chromatin Club!
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
Excited for this summer’s NYC Chromatin Club!
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
May 5, 2025 at 3:01 AM
Excited for this summer’s NYC Chromatin Club!
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!
#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
Awesome NYC chem bio meeting yesterday🤩
Keynote Tom Muir led to a mini-reunion together with @nshahlab.bsky.social!
Keynote Tom Muir led to a mini-reunion together with @nshahlab.bsky.social!
May 2, 2025 at 12:47 AM
Awesome NYC chem bio meeting yesterday🤩
Keynote Tom Muir led to a mini-reunion together with @nshahlab.bsky.social!
Keynote Tom Muir led to a mini-reunion together with @nshahlab.bsky.social!
Reposted by Yael David
Primary @natcomms.nature.com article: "The molecular basis of Human FN3K mediated phosphorylation of glycated substrates" from Leemore Joshua-Tor, Yael @davidlabmsk.bsky.social, and colleagues.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The molecular basis of Human FN3K mediated phosphorylation of glycated substrates - Nature Communications
Garg et al. determined structures of human Fructosamine-3-kinase (FN3K) bound with different nucleotide analogues and a small molecule sugar mimic substrate. Accompanied by biochemical analysis, they ...
www.nature.com
April 17, 2025 at 3:27 PM
Primary @natcomms.nature.com article: "The molecular basis of Human FN3K mediated phosphorylation of glycated substrates" from Leemore Joshua-Tor, Yael @davidlabmsk.bsky.social, and colleagues.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Big thanks to Viraj for the lovely and thoughtful write-up on our collaboration with Leemor! And major shoutout to Yang from my lab for the gorgeous biochemistry—so proud! ✨👏🧪
Check out our article in @cp-trendsbiochem.bsky.social
highlighting the elegant work by Joshua-Tor lab, @davidlabmsk.bsky.social, and team .Their findings shed light on the structural basis of FN3K function and open doors for targeting glycation-related diseases. @sanniejculbertson.bsky.social
highlighting the elegant work by Joshua-Tor lab, @davidlabmsk.bsky.social, and team .Their findings shed light on the structural basis of FN3K function and open doors for targeting glycation-related diseases. @sanniejculbertson.bsky.social
FN3K: the (un)sweetest kinase
Fructosamine 3-kinase (FN3K) mitigates excessive protein glycation by phosphorylating and destabilizing fructosamines, preventing irreversible advance…
www.sciencedirect.com
April 7, 2025 at 11:51 PM
Big thanks to Viraj for the lovely and thoughtful write-up on our collaboration with Leemor! And major shoutout to Yang from my lab for the gorgeous biochemistry—so proud! ✨👏🧪
It’s going to be a blast!!!
Couldn’t ask for a better partner 🤩
Come hang out with us if you are at the ASBMB next week!
Couldn’t ask for a better partner 🤩
Come hang out with us if you are at the ASBMB next week!
Excited to be co-chairing the Chemical tools to reveal new biology theme with @davidlabmsk.bsky.social!
"Chemical tools to reveal new biology" curated by @gburslem.bsky.social & @davidlabmsk.bsky.social.
"Interorganellar signaling and communication" designed by Navdeep Chandel & Isha Jain.
"Lipids and membranes" selected by @judisimcox.bsky.social & @gerryhammond.bsky.social
"Interorganellar signaling and communication" designed by Navdeep Chandel & Isha Jain.
"Lipids and membranes" selected by @judisimcox.bsky.social & @gerryhammond.bsky.social
April 7, 2025 at 11:46 PM
It’s going to be a blast!!!
Couldn’t ask for a better partner 🤩
Come hang out with us if you are at the ASBMB next week!
Couldn’t ask for a better partner 🤩
Come hang out with us if you are at the ASBMB next week!
Reposted by Yael David
Sign up here if you want to receive an email about our next session (April 22nd in the Columbia med school) docs.google.com/forms/d/e/1F...
@davidlabmsk.bsky.social @kelseymonson.bsky.social @stearnslab.bsky.social
@davidlabmsk.bsky.social @kelseymonson.bsky.social @stearnslab.bsky.social
Postdoc Night Science (NYC)
Sign up here for monthly meetings for postdoctoral fellows in the NYC area to practice the creative scientific process. For questions contact Itai Yanai ([email protected])
docs.google.com
March 17, 2025 at 3:07 AM
Sign up here if you want to receive an email about our next session (April 22nd in the Columbia med school) docs.google.com/forms/d/e/1F...
@davidlabmsk.bsky.social @kelseymonson.bsky.social @stearnslab.bsky.social
@davidlabmsk.bsky.social @kelseymonson.bsky.social @stearnslab.bsky.social
Had an absolute blast at the @mskcancercenter.bsky.social PDA Night Science event w/ @itaiyanai.bsky.social —improv exercises, big ideas, & a glimpse into the brilliant future of science! A pleasure to be hosted for such an inspiring and fun evening. #NightScience #FutureOfScience
March 16, 2025 at 2:16 PM
Had an absolute blast at the @mskcancercenter.bsky.social PDA Night Science event w/ @itaiyanai.bsky.social —improv exercises, big ideas, & a glimpse into the brilliant future of science! A pleasure to be hosted for such an inspiring and fun evening. #NightScience #FutureOfScience
Anything involving @itaiyanai.bsky.social? Count me in—no questions asked here either!!
#MaybeIShouldHaveReadTheFinePrint
#MaybeIShouldHaveReadTheFinePrint
Postdoc Night Science NYC! Next session is Friday 4-6pm at MSK, to learn and practice the creative scientific process! The topic this time is the import/export of ideas. Yael David join us too! @davidlabmsk.bsky.social
Limited spots: docs.google.com/forms/d/12bB... @kelseymonson.bsky.social
Limited spots: docs.google.com/forms/d/12bB... @kelseymonson.bsky.social
March 11, 2025 at 1:10 AM
Anything involving @itaiyanai.bsky.social? Count me in—no questions asked here either!!
#MaybeIShouldHaveReadTheFinePrint
#MaybeIShouldHaveReadTheFinePrint
TFW you watch the @academyawards.bsky.social awards and see you face in the @mskcancercenter.bsky.social ad 🤩
#Oscars
ispot.tv/ad/6wa1/memori…
#Oscars
ispot.tv/ad/6wa1/memori…
March 3, 2025 at 1:40 AM
TFW you watch the @academyawards.bsky.social awards and see you face in the @mskcancercenter.bsky.social ad 🤩
#Oscars
ispot.tv/ad/6wa1/memori…
#Oscars
ispot.tv/ad/6wa1/memori…
Wow, this means a lot coming from the folks @epicypher.bsky.social !!
So lucky to have you as collaborators and hope that the next big hit will come from our joint work!! 🙏🏻🤩
So lucky to have you as collaborators and hope that the next big hit will come from our joint work!! 🙏🏻🤩
🧬🧪SO excited to read this paper - new from @davidlabmsk.bsky.social highlighting the role of nucleosome occupancy in Hep B viral infection + discovering a new potential therapeutic strategy for Hep B. A great story of how basic research can lead to new treatment strategies🌟
I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
February 24, 2025 at 11:01 AM
Wow, this means a lot coming from the folks @epicypher.bsky.social !!
So lucky to have you as collaborators and hope that the next big hit will come from our joint work!! 🙏🏻🤩
So lucky to have you as collaborators and hope that the next big hit will come from our joint work!! 🙏🏻🤩
Huge thank you, Darko, for the super kind words and for this shoutout 💪🏻🤩🙏🏻
Absolutely fantastic work from the magnificent @davidlabmsk.bsky.social lab! Incredible science and amazing out-of-the-box approach. Congrats to all the authors and highly recommend the read. 🙌
I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
February 24, 2025 at 11:00 AM
Huge thank you, Darko, for the super kind words and for this shoutout 💪🏻🤩🙏🏻
I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
A nucleosome switch primes hepatitis B virus infection
A reconstituted cccDNA platform facilitated the discovery of an early chromatinization
event that promotes transcription of the hepatitis B virus (HBV) regulatory X gene.
The use of a small-molecule c...
www.cell.com
February 21, 2025 at 5:31 PM
I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
Congrats Leemor Joshua-Tor @cshlaboratory.bsky.social for this new paper characterizing human FN3K!
Happy to play a role in the biochemical analysis, beautifully done by my TPCB rock star student Yang Xiao 💪🏻🤩
@mskcancercenter.bsky.social
@weillcornell.bsky.social
www.nature.com/articles/s41...
Happy to play a role in the biochemical analysis, beautifully done by my TPCB rock star student Yang Xiao 💪🏻🤩
@mskcancercenter.bsky.social
@weillcornell.bsky.social
www.nature.com/articles/s41...
The molecular basis of Human FN3K mediated phosphorylation of glycated substrates - Nature Communications
Garg et al. determined structures of human Fructosamine-3-kinase (FN3K) bound with different nucleotide analogues and a small molecule sugar mimic substrate. Accompanied by biochemical analysis, they ...
urldefense.com
January 22, 2025 at 7:40 PM
Congrats Leemor Joshua-Tor @cshlaboratory.bsky.social for this new paper characterizing human FN3K!
Happy to play a role in the biochemical analysis, beautifully done by my TPCB rock star student Yang Xiao 💪🏻🤩
@mskcancercenter.bsky.social
@weillcornell.bsky.social
www.nature.com/articles/s41...
Happy to play a role in the biochemical analysis, beautifully done by my TPCB rock star student Yang Xiao 💪🏻🤩
@mskcancercenter.bsky.social
@weillcornell.bsky.social
www.nature.com/articles/s41...
Just another magical day at the office in our enchanted forest…
Happy holidays from the David lab!!
🎄🕎🥂
Happy holidays from the David lab!!
🎄🕎🥂
December 17, 2024 at 12:25 PM
Just another magical day at the office in our enchanted forest…
Happy holidays from the David lab!!
🎄🕎🥂
Happy holidays from the David lab!!
🎄🕎🥂
Almost 8 years since our first encounter, 2 years as a tech, & 5 years as a joint PhD student with Samuel Bakhoum, I am so proud to see Albert defend his thesis, & the amazing David lab cheering from the lines.
Great science & friends, & one sword of course🤩🫶🏻
Great science & friends, & one sword of course🤩🫶🏻
December 6, 2024 at 3:46 AM
Almost 8 years since our first encounter, 2 years as a tech, & 5 years as a joint PhD student with Samuel Bakhoum, I am so proud to see Albert defend his thesis, & the amazing David lab cheering from the lines.
Great science & friends, & one sword of course🤩🫶🏻
Great science & friends, & one sword of course🤩🫶🏻