César de la Fuente
@delafuentelab.bsky.social
Presidential Associate Professor @upenn.edu - using AI to reimagine antibiotic discovery and peptide design. Previously @MIT, @UBC
🔗 https://delafuentelab.seas.upenn.edu
🔗 https://delafuentelab.seas.upenn.edu
Thank you @asm.org for inviting me to the first ASM event in India. The IISc Global Research Symposium on the One Health Approach to Antimicrobial Resistance was a powerful example of what’s possible for AMR research there. The scientific talent here is extraordinary—excited to see what comes next.
November 25, 2025 at 10:45 AM
Thank you @asm.org for inviting me to the first ASM event in India. The IISc Global Research Symposium on the One Health Approach to Antimicrobial Resistance was a powerful example of what’s possible for AMR research there. The scientific talent here is extraordinary—excited to see what comes next.
It’s an honor and a privilege to be included in the 2025 #FuturePerfect25 list, which celebrates the fight for a healthier, fairer future. I’m humbled to be part of this ambitious project from @voxdotcom.bsky.social and in the company of so many changemakers I revere.
www.vox.com/future-perfe...
www.vox.com/future-perfe...
The 2025 Future Perfect 25
Meet the heroes keeping global progress alive.
www.vox.com
November 21, 2025 at 9:13 AM
It’s an honor and a privilege to be included in the 2025 #FuturePerfect25 list, which celebrates the fight for a healthier, fairer future. I’m humbled to be part of this ambitious project from @voxdotcom.bsky.social and in the company of so many changemakers I revere.
www.vox.com/future-perfe...
www.vox.com/future-perfe...
Honored to be recognized once again among the top 1% of the world’s most highly cited researchers by @clarivate.com. This is a testament to the relentless curiosity and hard work of my team. Grateful for their dedication to pushing the frontiers of science.
November 20, 2025 at 9:19 AM
Honored to be recognized once again among the top 1% of the world’s most highly cited researchers by @clarivate.com. This is a testament to the relentless curiosity and hard work of my team. Grateful for their dedication to pushing the frontiers of science.
Reposted by César de la Fuente
Deep learning speeds the search for new antibiotic scaffolds #NBTNV - @delafuentelab.bsky.social go.nature.com/47fxSSv
Deep learning speeds the search for new antibiotic scaffolds - Nature Biotechnology
A deep learning model trained on experimental data from high-throughput screening identifies structurally novel antimicrobial compounds.
go.nature.com
October 29, 2025 at 2:07 PM
Deep learning speeds the search for new antibiotic scaffolds #NBTNV - @delafuentelab.bsky.social go.nature.com/47fxSSv
¡Gracias por la entrevista! Fue un placer hablar con @farodevigo.es sobre el trabajo de mi laboratorio. Galicia tiene una oportunidad única para convertirse en un foco de biotecnología y de IA. Un auténtico placer estar de vuelta en nuestra preciosa tierra.
César de la Fuente, biotecnólogo y profesor de la Universidad de Pensilvania: «Mi sueño es que Galicia se convierta en un polo de biotecnología y de IA a nivel mundial»
«La IA de por sí no es tan útil si no tienes buenos datos para entrenarla»
«Mi sueño es que Galicia se convierta en un polo de biotecnología y de IA a nivel mundial», dice el científico gallego, Premio Princesa de Girona
www.farodevigo.es
November 19, 2025 at 3:42 PM
¡Gracias por la entrevista! Fue un placer hablar con @farodevigo.es sobre el trabajo de mi laboratorio. Galicia tiene una oportunidad única para convertirse en un foco de biotecnología y de IA. Un auténtico placer estar de vuelta en nuestra preciosa tierra.
Reposted by César de la Fuente
2/ In the lab, @delafuentelab.bsky.social develops AI models to identify antibiotics in existing organisms and even in extinct species. 🦣💊
Want to learn more about his career and latest discoveries? Read it here: 👇
Want to learn more about his career and latest discoveries? Read it here: 👇
AI Uncovers New Antibiotics in Ancient Microbes - Penn Engineering Blog
They’ve survived for billions of years in boiling acid, deep-sea vents and salt flats. Now, some of Earth’s oldest life forms — microbes called Archaea … Read More ›
blog.seas.upenn.edu
November 18, 2025 at 4:06 PM
2/ In the lab, @delafuentelab.bsky.social develops AI models to identify antibiotics in existing organisms and even in extinct species. 🦣💊
Want to learn more about his career and latest discoveries? Read it here: 👇
Want to learn more about his career and latest discoveries? Read it here: 👇
Reposted by César de la Fuente
1/ 🤔🧬 Can artificial intelligence help us discover new antibiotics?
Researcher and #laCaixaFoundFellow @delafuentelab.bsky.social (@upenn.bsky.social) shares his project and his vision for the new #CaixaResearchInstitute. 👀👇
Researcher and #laCaixaFoundFellow @delafuentelab.bsky.social (@upenn.bsky.social) shares his project and his vision for the new #CaixaResearchInstitute. 👀👇
November 18, 2025 at 4:06 PM
1/ 🤔🧬 Can artificial intelligence help us discover new antibiotics?
Researcher and #laCaixaFoundFellow @delafuentelab.bsky.social (@upenn.bsky.social) shares his project and his vision for the new #CaixaResearchInstitute. 👀👇
Researcher and #laCaixaFoundFellow @delafuentelab.bsky.social (@upenn.bsky.social) shares his project and his vision for the new #CaixaResearchInstitute. 👀👇
Reposted by César de la Fuente
The One Health Microbiome Center at Penn State will host Dr. César de la Fuente, AI biologist and Presidential Associate Professor at the University of Pennsylvania, on December 5 at 11 a.m. Registration required (link in article.)
📍 Foster Auditorium, Paterno Library
www.psu.edu/news/huck-in...
📍 Foster Auditorium, Paterno Library
www.psu.edu/news/huck-in...
World leader in AI and antibiotic discovery to deliver lecture at Penn State | Penn State University
César de la Fuente, Presidential Associate Professor and leader of the Machine Biology Group at University of Pennsylvania, will speak at 11 a.m. on Dec. 5 in Foster Auditorium in the Paterno Library ...
www.psu.edu
November 6, 2025 at 8:08 PM
The One Health Microbiome Center at Penn State will host Dr. César de la Fuente, AI biologist and Presidential Associate Professor at the University of Pennsylvania, on December 5 at 11 a.m. Registration required (link in article.)
📍 Foster Auditorium, Paterno Library
www.psu.edu/news/huck-in...
📍 Foster Auditorium, Paterno Library
www.psu.edu/news/huck-in...
Spoke at @elrig.org SCIENCE in Liverpool about moving faster on antibiotics with AI and high-qualiy training data. Amazing community. The energy in the room was the best part. You’ll Never Walk Alone.
November 17, 2025 at 10:13 AM
Spoke at @elrig.org SCIENCE in Liverpool about moving faster on antibiotics with AI and high-qualiy training data. Amazing community. The energy in the room was the best part. You’ll Never Walk Alone.
Grateful to Elizabeth Stivison for covering our work with superstars Marcelo Torres and Anna Crysler on training AI to uncover novel antibiotics in @asbmb.bsky.social Today! Excited to see growing momentum at the intersection of AI and antibiotic discovery.
November 14, 2025 at 11:13 AM
Grateful to Elizabeth Stivison for covering our work with superstars Marcelo Torres and Anna Crysler on training AI to uncover novel antibiotics in @asbmb.bsky.social Today! Excited to see growing momentum at the intersection of AI and antibiotic discovery.
Very much looking forward to it!
The One Health Microbiome Center at Penn State will host Dr. César de la Fuente, AI biologist and Presidential Associate Professor at the University of Pennsylvania, on December 5 at 11 a.m. Registration required (link in article.)
📍 Foster Auditorium, Paterno Library
www.psu.edu/news/huck-in...
📍 Foster Auditorium, Paterno Library
www.psu.edu/news/huck-in...
World leader in AI and antibiotic discovery to deliver lecture at Penn State | Penn State University
César de la Fuente, Presidential Associate Professor and leader of the Machine Biology Group at University of Pennsylvania, will speak at 11 a.m. on Dec. 5 in Foster Auditorium in the Paterno Library ...
www.psu.edu
November 14, 2025 at 3:56 AM
Very much looking forward to it!
Reposted by César de la Fuente
🚨 In case you missed it, Dr. César de la Fuente will be joining us on December 5 at 11 A.M. as a part of our OHMC Seminar Series in Foster Auditorium at the Paterno Library.
The lecture is open to the Penn State community, registration details can be found here: forms.cloud.microsoft/r/yP0GQfwkEz
The lecture is open to the Penn State community, registration details can be found here: forms.cloud.microsoft/r/yP0GQfwkEz
November 10, 2025 at 4:32 PM
🚨 In case you missed it, Dr. César de la Fuente will be joining us on December 5 at 11 A.M. as a part of our OHMC Seminar Series in Foster Auditorium at the Paterno Library.
The lecture is open to the Penn State community, registration details can be found here: forms.cloud.microsoft/r/yP0GQfwkEz
The lecture is open to the Penn State community, registration details can be found here: forms.cloud.microsoft/r/yP0GQfwkEz
Reposted by César de la Fuente
🚀 Big news! On December 5, we’re thrilled to welcome AI-biologist legend César de la Fuente to campus for a lecture on using machine learning to discover the next generation of antibiotics.
November 10, 2025 at 5:19 PM
🚀 Big news! On December 5, we’re thrilled to welcome AI-biologist legend César de la Fuente to campus for a lecture on using machine learning to discover the next generation of antibiotics.
Reposted by César de la Fuente
New primer alert! Fantastic insight into how to apply machine learning and AI in microbiology. A must read. @microbiologysociety.org @delafuentelab.bsky.social www.microbiologyresearch.org/content/jour...
Microbial Primer: Artificial intelligence for microbiologists
Artificial intelligence (AI) and machine learning (ML) are reshaping microbiology, enabling rapid antibiotic discovery, resistance prediction and clinical diagnostics. For microbiologists, the goal is...
www.microbiologyresearch.org
November 13, 2025 at 6:07 PM
New primer alert! Fantastic insight into how to apply machine learning and AI in microbiology. A must read. @microbiologysociety.org @delafuentelab.bsky.social www.microbiologyresearch.org/content/jour...
Thank you @microbiologysociety.org for featuring our new article “Artificial intelligence for microbiologists”, a practical primer for anyone in microbiology wanting to get started with AI and ML. Led by superstar PhD student Hanqun Cao.
🖥️ How is artificial intelligence being applied to microbiological research?
As part of the Microbial Primers series, @delafuentelab.bsky.social publish a guide on the developments in machine learning (ML) and their applications🦠
#Microbiology #ArtificialIntelligence #AntibioticDiscovery
As part of the Microbial Primers series, @delafuentelab.bsky.social publish a guide on the developments in machine learning (ML) and their applications🦠
#Microbiology #ArtificialIntelligence #AntibioticDiscovery
November 13, 2025 at 4:16 PM
Thank you @microbiologysociety.org for featuring our new article “Artificial intelligence for microbiologists”, a practical primer for anyone in microbiology wanting to get started with AI and ML. Led by superstar PhD student Hanqun Cao.
🎙️ Honored to take part in EIRNABio’s “10 Questions” — discussing AI-driven antibiotic discovery, the future of digital biology, and what inspires my journey.💡🔬 eirnabio.com/10-questions...
10 Questions with Professor Cesar de la Fuente
Professor Cesar de la Fuente is a Sloan Fellow and an elected Fellow of AIMBE, becoming one of the youngest ever to be inducted.
eirnabio.com
November 13, 2025 at 9:22 AM
🎙️ Honored to take part in EIRNABio’s “10 Questions” — discussing AI-driven antibiotic discovery, the future of digital biology, and what inspires my journey.💡🔬 eirnabio.com/10-questions...
Thank you Bob Service for highlighting in @science.org our work using AI to uncover antibiotics from archaea. Grateful for the thoughtful coverage—and excited by growing interest in these ancient microbes, a distinct branch of the tree of life.
November 12, 2025 at 8:37 AM
Thank you Bob Service for highlighting in @science.org our work using AI to uncover antibiotics from archaea. Grateful for the thoughtful coverage—and excited by growing interest in these ancient microbes, a distinct branch of the tree of life.
Huge thanks to @nikomccarty.bsky.social and the @asimovpress.bsky.social Podcast for the incredible gift—a book encoded in DNA! 🧬📖
A beautiful fusion of science, art, and storytelling.
A beautiful fusion of science, art, and storytelling.
November 10, 2025 at 9:32 AM
Huge thanks to @nikomccarty.bsky.social and the @asimovpress.bsky.social Podcast for the incredible gift—a book encoded in DNA! 🧬📖
A beautiful fusion of science, art, and storytelling.
A beautiful fusion of science, art, and storytelling.
🎥 Proud to share my @upenn.edu Penn Today video, “Uncovering New Antibiotics with AI.” See how AI is helping us find tomorrow’s antibiotics—today. Watch: penntoday.upenn.edu/news/uncover...
Uncovering new antibiotics with AI | Penn Today
César de la Fuente leverages machine learning to accelerate the discovery of lifesaving drugs and help reduce antibiotic resistance, a rising global health problem.
penntoday.upenn.edu
November 6, 2025 at 10:54 AM
🎥 Proud to share my @upenn.edu Penn Today video, “Uncovering New Antibiotics with AI.” See how AI is helping us find tomorrow’s antibiotics—today. Watch: penntoday.upenn.edu/news/uncover...
En mi charla de Frontiers in Genomics de UNAM MX exploro cómo la IA puede transformar el descubrimiento de antibióticos: de la minería de datos a la biología digital. 💡🔬 ¡No te la pierdas!
👉 www.youtube.com/watch?app=de...
👉 www.youtube.com/watch?app=de...
Frontiers in Genomics - César de la Fuente - 23 septiembre 2025 9am
YouTube video by LCG UNAM
www.youtube.com
November 5, 2025 at 11:46 AM
En mi charla de Frontiers in Genomics de UNAM MX exploro cómo la IA puede transformar el descubrimiento de antibióticos: de la minería de datos a la biología digital. 💡🔬 ¡No te la pierdas!
👉 www.youtube.com/watch?app=de...
👉 www.youtube.com/watch?app=de...
Science runs on curiosity… and cookies. 🍪🧪 Thanks The Scientist for spotlighting our “Cookie Wednesday,” a sweet way to fuel cross-disciplinary creativity.
www.the-scientist.com/scientists-s...
www.the-scientist.com/scientists-s...
Scientists Spill Their Quirky Lab Traditions and Superstitions
From lucky tokens that keep instruments running smoothly to a weekly cookie break, scientists told us about their favorite lab customs and beliefs.
www.the-scientist.com
November 3, 2025 at 12:08 PM
Science runs on curiosity… and cookies. 🍪🧪 Thanks The Scientist for spotlighting our “Cookie Wednesday,” a sweet way to fuel cross-disciplinary creativity.
www.the-scientist.com/scientists-s...
www.the-scientist.com/scientists-s...
My friend #EltonBrand @sixersnba.bsky.social and I at my lab's Halloween party talking about the future of AI and Sports. What are your thoughts? Do you think #RudyFernandez and #SergeiIbaka would approve of our costumes?😉 Wishing everyone a Happy Halloween! 🎃
October 31, 2025 at 12:14 PM
My friend #EltonBrand @sixersnba.bsky.social and I at my lab's Halloween party talking about the future of AI and Sports. What are your thoughts? Do you think #RudyFernandez and #SergeiIbaka would approve of our costumes?😉 Wishing everyone a Happy Halloween! 🎃
Big day at @upenn.edu ! Honored to host my friend Elton Brand from @sixersnba.bsky.social for a deep dive into how we’re using AI to fight antimicrobial resistance. Thanks for the sharp questions and team spirit, Elton! 🧪🏀
October 30, 2025 at 2:08 PM
Big day at @upenn.edu ! Honored to host my friend Elton Brand from @sixersnba.bsky.social for a deep dive into how we’re using AI to fight antimicrobial resistance. Thanks for the sharp questions and team spirit, Elton! 🧪🏀
It was an honor to participate in the third course organized by @mobilise.bsky.social @i3suporto.bsky.social, sharing experiences with incredible people. A privilege to learn, share, and connect with such an amazing group.
October 30, 2025 at 10:35 AM
It was an honor to participate in the third course organized by @mobilise.bsky.social @i3suporto.bsky.social, sharing experiences with incredible people. A privilege to learn, share, and connect with such an amazing group.
Reposted by César de la Fuente
Feed: "Nature Biotechnology"
By: Tommaso Biancalani
By: Tommaso Biancalani
Deep-learning-based virtual screening of antibacterial compounds
Antibacterial compounds are discovered by combining phenotypic screening with deep learning.
www.nature.com
October 24, 2025 at 8:37 PM
Feed: "Nature Biotechnology"
By: Tommaso Biancalani
By: Tommaso Biancalani