Mena Farag
@drmfarag.bsky.social
1.4K followers 1.7K following 14 posts
Neurology south London trainee 🧠 (OOP-R; ST6) ⋅ Clinical Research Fellow & PhD candidate based at UCL Queen Square Institute of Neurology — #HD-YAS https://orcid.org/0000-0002-0679-0117
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Reposted by Mena Farag
natrevneurol.nature.com
Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
movementdisorders.onlinelibrary.wiley.com
drmfarag.bsky.social
For the first time, we show that baseline CSF PENK predicts longitudinal striatal atrophy and also outperforms NfL in distinguishing HD-ISS 0 vs 1, supporting CSF PENK as a striatum-specific biomarker to enrich early HD trials and inform future preventive trial design.
Reposted by Mena Farag
thelancet.com
The oncogenic KRAS mutation has been the subject of intense investigation. In The Lancet, a new phase 3 trial reports on adagrasib versus docetaxel in KRASG12C-mutated non-small-cell lung cancer.

This and more in our latest issue 👉 bit.ly/4mi7T1y
Cover of The Lancet, August 9 2025 issue. Quote: "Adagrasib demonstrated statistically significant improvements in progression-free survival over docetaxel in patients with previously treated KRASG12C-mutated non-small cell lung cancer."
Reposted by Mena Farag
drl-bo.bsky.social
I am unbelievably proud to have my first senior author paper published today! It was a long slog through multiple review cycles but we got there!

A big thank you to my lab members and all the collaborators and participants who contributed to this work! 🥲
drmfarag.bsky.social
Super fun first 5K #RUN4HDYO! 🏃 💨 🏃‍♀️‍

Over £2500 raised for the Olivia (Liv) Martinez Scholarship Fund for HDYO - honouring an amazing ambassador I met at #HDYO Congress in Glasgow in 2023. Liv's kindness and passion touched so many. @ucl-hd.bsky.social @uclqsion.bsky.social
Reposted by Mena Farag
drmfarag.bsky.social
Check out the March 2025 edition of the #HD Clinical Trials Update, now available online in the Journal of Huntington's Disease @profwild.bsky.social 🔓 Open access link: journals.sagepub.com/doi/10.1177/... @ucl-hd.bsky.social @uclbrainscience.bsky.social @uclqsion.bsky.social
Reposted by Mena Farag
drmfarag.bsky.social
Thank you HDYO for the opportunity to talk about HD-YAS at #HDYO Congress 2025! Truly an inspiring community and family — and this absolutely drives all the work we do! @ucl-hd.bsky.social @uclqsion.bsky.social