Author | Lightnews

Gonzalo Borrego-Yaniz

@goboru.bsky.social

180 followers 290 following 85 posts

Genomics and epigenomics to better understand giant cell arteritis and other rheumatic diseases 🖥️🧬 Philosophy and sciart enthusiast. 🏳️‍🌈 PhD Student at IPBLN-CSIC in Granada, Spain. He/him

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Gonzalo Borrego-Yaniz @goboru.bsky.social · Aug 28

New paper just out (online first) in Arthritis & Rheumatology! 🎉

We mapped the epigenetic changes (DNA methylation) in GCA-affected arteries. Largest cohort to date; findings point to new pathways relevant to disease mechanisms 🧵

Read: doi.org/10.1002/art....

cc @ipblncsic.bsky.social

Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients

Objectives Giant cell arteritis (GCA) is a large-vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by ...

doi.org

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Gonzalo Borrego-Yaniz @goboru.bsky.social · 5d

Sobre nuestro último estudio de metilación del ADN en arterias de pacientes de arteritis de células gigantes!! 👇🏼👇🏼

CSIC Andalucía y Extremadura @csicandalextrem.bsky.social · 6d

Descubren señales moleculares en el ADN que explican la inflamación crónica de las arterias a partir de los 50 años

El @ipblncsic.bsky.social identifica también células inmunitarias “agotadas” que podrían explicar por qué la inflamación persiste en la arteritis de células gigantes

t.ly/tTyjB

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Reposted by Gonzalo Borrego-Yaniz

Ming Tommy Tang @tommytang.bsky.social · 6d

Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions www.nature.com/articles/s4...

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Reposted by Gonzalo Borrego-Yaniz

El Mundo Today @elmundotoday.com · 15d

Gracias a un superordenador cuántico, la entidad está en condiciones de asegurar que la letra «I» de sus siglas significa «investigación».

Puedes leer la información completa en la web: www.elmundotoday.com/2025/10/el-c...

Contenido patrocinado por @csicdivulga.bsky.social.

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Gonzalo Borrego-Yaniz @goboru.bsky.social · 20d

Reminded me of that quote from The Office: "Apparently, in the medicine community, negative means good, which makes absolutely no sense" 😂

Gonzalo Borrego-Yaniz @goboru.bsky.social · 27d

Take a look! Useful for quick reference and if you get lost with all the -seq omic technologies 😱

Ming Tommy Tang @tommytang.bsky.social · 27d

SequencEnG: An interactive learning resource for next-generation sequencing (NGS) techniques education.knoweng.org/sequenceng/
It is impossible to be an expert of all those data types
but once you have the core solid foundation
you can learn how to analyze a new data type as needed

Reposted by Gonzalo Borrego-Yaniz

Antonio Martínez Ron @aberron.bsky.social · 29d

Premio Nobel de Medicina 2025 para los descubridores de las células guardianas del sistema inmunitario www.eldiario.es/1_c12bc9?utm...

Premio Nobel de Medicina 2025 para los descubridores de las células guardianas del sistema inmunitario

El comité reconoce a Mary E. Brunkow, Fred Ramsdell y Shimon Sakaguchi por descubrir los linfocitos T reguladores, que vigilan a otras células inmunitarias y garantizan que nuestro sistema inmunitario...

www.eldiario.es

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Reposted by Gonzalo Borrego-Yaniz

PRISMA LGTBIQA+ @prismaciencia.bsky.social · 29d

✨ ¡Ya puedes reservar tu plaza para la Conferencia PRISMA 2025!
📅 13, 14 y 15 de noviembre – Barcelona
Un espacio seguro e inclusivo para compartir ciencia y experiencias LGTBIQA+ en CTI.
🔗 prismaciencia.org/conferencia-...

#ConferenciaPRISMA #DiversidadEnCiencia #LGTBIQA

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Reposted by Gonzalo Borrego-Yaniz

Andrea Ganna @andganna.bsky.social · Sep 30

🧬💥 Do the genetics that make you develop a disease also help you survive it? Not much.

Our new study in Nature Genetics including 9 disease and 7 biobanks shows:

• Susceptibility variants ≠ survival
• PRSs for onset weak at predicting progression
• Lifespan PRS predicts survival better

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Gonzalo Borrego-Yaniz @goboru.bsky.social · 29d

Cover in Science Immunology by Rioka Hayama #CoverArtGallery

Reposted by Gonzalo Borrego-Yaniz

agenciasinc.es @agenciasinc.es · Oct 2

La primatóloga y conservacionista Jane Goodall ha muerto a los 91 años. Dedicó su vida a comprender el comportamiento de los chimpancés salvajes y se convirtió en una de las figuras más influyentes del ambientalismo. Su legado permanecerá siempre vivo shorturl.at/lIECu

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Gonzalo Borrego-Yaniz @goboru.bsky.social · Oct 2

We’d like to know too… #graphicmedicine #rheumsky #medsky

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Reposted by Gonzalo Borrego-Yaniz

Saez-Rodriguez Group @saezlab.bsky.social · Sep 26

We are hiring a Postdoctoral Fellow in Computational Biology at EMBL-EBI (Cambridge, UK). Focus: methods to study cell–cell communication from sc/spatial omics data (building on LIANA+ and NicheNet), in collab with @yvansaeys.bsky.social VIB/Ghent.

Details & apply by 13/10/25: tinyurl.com/4shdw8dk

Current Vacancies

Whether you're a scientist, IT specialist, accountant or administrator, you'll help us tackle the challenges of improving human health & biodiversity in the face of climate change on a global scal...

tinyurl.com

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Reposted by Gonzalo Borrego-Yaniz

IPBLN-CSIC @ipblncsic.bsky.social · Sep 25

👉¿Os imagináis si en algún momento pudiéramos usar la genética para predecir el riesgo que una persona podría tener a la hora de desarrollar ciertas enfermedades? ¡Ven a la charla de Carlos para descubrirlo!

📅 Recuerda que el 26 de Septiembre es la NOCHE EUROPEA de l@s INVESTIGADOR@S.

@csic.es

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Reposted by Gonzalo Borrego-Yaniz

Eberl Lab 👨🏻‍🔬👩🏽‍💻🔬🧫 @eberllab.bsky.social · May 23

The perfect end to a great #gammadeltatoronto conference: our latest review has just been published in Advances in Immunology!

"Modulation of humoral immunity by γδ T cells: A potential adjuvant strategy for vaccination"

👉🏼 authors.elsevier.com/a/1l8ltErwXf...

#gdTcells @forum-gd.bsky.social

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Reposted by Gonzalo Borrego-Yaniz

Lluis Montoliu @lluismontoliu.bsky.social · Sep 23

Mañana presentaré mi último libro #SerCientífico publicado por Comares en Granada, a las 19:00, y me acompañarán Federico Zurita @canalugr.bsky.social y Marga Sánchez Romero vicerrectora y nos moderará Elena Sanz directora de @es.theconversation.com
centroculturalcomares.com/presentacion...

Centro Cultural Comares

24.09.25

centroculturalcomares.com

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Reposted by Gonzalo Borrego-Yaniz

Nature Portfolio @natureportfolio.nature.com · Sep 18

A Nature Careers feature explores the ways scientific societies, journals, editors and researchers are pushing back against mean-spirited peer reviews. #Academicsky 🧪

‘Lipstick on a pig’: how to fight back against a peer-review bully

Scientific societies, journals, editors and researchers are pushing back against mean-spirited peer reviews.

go.nature.com

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Gonzalo Borrego-Yaniz @goboru.bsky.social · Sep 19

Wow, impressive work!! 👏🏼

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Reposted by Gonzalo Borrego-Yaniz

PLOS Biology @plosbiology.org · Sep 19

How do your #linguistic, #economic & #gender backgrounds impact your #scientific productivity? @tatsuya-amano.bsky.social & co reveal that being a woman, a non-native English speaker, and from a low-income country is associated with a 70% reduction in productivity @plosbiology.org 🧪 plos.io/4n3RLRQ

Scientific productivity gap based on English-language peer-reviewed papers. Shown are the maximum % differences in the number of peer-reviewed papers published by female native English speakers from a high-income country (-45%), female non-native English speakers from a high-income country (-60%), and female non-native English speakers from a lower-middle income country (-70%), compared to male native English speakers from a high-income country (red flag). Credit: Tatsuya Amano

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Reposted by Gonzalo Borrego-Yaniz

Ewan Birney @ewanbirney.bsky.social · Sep 15

Bioinformaticians / computational biologists take note - know where you should take your OS tool chain from and do not introduce backdoors.

James Bonfield @jbonfield.bsky.social · Sep 15

Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.

Ie: it's not us (Samtools team)! Be warned

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Reposted by Gonzalo Borrego-Yaniz

The University of Manchester @manchester.ac.uk · Sep 12

Confidence, connection and hope - how one mentoring programme is making a real difference 🌈

New research shows how a pioneering programme for LGBTQIA+ young people, delivered by Free2B, is giving young people a space where they can be themselves without fear.

www.manchester.ac.uk/about/news/b...

Mentoring programme gives big mental health boost to LGBTQIA+ teens

A mentoring programme for LGBTQIA+ young people is making a real difference to their mental health, according to new research from The University of Manchester.The programme delivered by Free2B pairs ...

www.manchester.ac.uk

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Reposted by Gonzalo Borrego-Yaniz

Nature Reviews Genetics @natrevgenet.nature.com · Sep 12

ICYMI: New online! Harnessing functional annotation to improve the accuracy and transferability of polygenic scores

Harnessing functional annotation to improve the accuracy and transferability of polygenic scores

Nature Reviews Genetics, Published online: 05 September 2025; doi:10.1038/s41576-025-00893-4The accuracy of polygenic scores (PGS) remains limited and poorly transferable across ancestries. In this Comment, Zeng and Visscher discuss how integrating functional annotations with whole-genome sequencing data can improve PGS by prioritizing likely causal variants shared across populations and by assigning greater weight to variants in biologically relevant regions.

www.nature.com

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Reposted by Gonzalo Borrego-Yaniz

Ming Tommy Tang @tommytang.bsky.social · Sep 8

23 tools to work with (single-cell) TCR/BCR-seq immune repertoire data 🧵 👇

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Gonzalo Borrego-Yaniz @goboru.bsky.social · Sep 8

For the next three months I am doing a stay at the University of Manchester! Prof. Gisela Orozco's lab, in a project working on ATAC-seq and CUT&Tag data. Happy to be here!! 🌸
(also my first time in the UK! 😊)
@manchester.ac.uk

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Reposted by Gonzalo Borrego-Yaniz

Drmaypole @drmaypole.bsky.social · Sep 2

Hard to overstate: we still have not gotten it right—that the #EMR does not facilitate connection with patients, but distracts from it. Overreliance on clinician data entry—and typing—contributes to burnout and diminishes the experience for all. #Graphicmedicine #medsky

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Reposted by Gonzalo Borrego-Yaniz

Fundación Ramón Areces @fundacionareces.bsky.social · Sep 2

‼️ HOY se abre el plazo de presentación de solicitudes de #ayudas para la realización de #tesis doctorales

Impulsa tu programa de #doctorado con la #frAreces 🚀

En nuestra web encontrarás todos los detalles de la #convocatoria

#ciencia #economia #derecho #humanidades #phd

Fundación Ramón Areces @fundacionareces.bsky.social · Jul 30

📢 El 2 de septiembre abrimos nueva convocatoria de #Ayudas para la realización de #TesisDoctorales

Prepárate para impulsar con la #frAreces tu carrera académica e investigadora

Bases y condiciones 🔎 www.fundacionareces.es/fundacionare...

#PhD #Doctorado #Ciencia #Economia #Humanidades

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