Hamish Stewart
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hamishs.bsky.social
Hamish Stewart
@hamishs.bsky.social
280 followers 290 following 100 posts
Analyzer evangelist and mass spectrometry enjoyer. Read about the Astral analyzer:
https://pubs.acs.org/doi/10.1021/acs.analchem.3c02856
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hamishs.bsky.social
Always enjoy a rare multi-reflection ToF publication. Fills in some gaps.
January 27, 2026 at 10:25 PM
Reposted by Hamish Stewart
kkmurray.bsky.social
(JASMS) [ASAP] Faces of Mass Spectrometry/Khatereh Motamedchaboki: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00430 (RSS) #MassSpecRSS #JASMS
[ASAP] Faces of Mass Spectrometry/Khatereh Motamedchaboki
Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00430
dlvr.it
January 10, 2026 at 5:06 PM
hamishs.bsky.social
Big evaluation of our Orbitrap Astral Zoom mass spectrometer by the Olsen group, now peer reviewed, published and open access.

www.sciencedirect.com/science/arti...
January 10, 2026 at 1:34 PM
Reposted by Hamish Stewart
proteomicsnews.bsky.social
@benneely.com it’s finally real!!
January 4, 2026 at 1:28 AM
hamishs.bsky.social
Our Orbitrap Astral Zoom mass spectrometer has won its first prize!

Nice little interview here with my teammate Johannes.
theanalyticalscientist.com/issues/2025/...
The Analytical Scientist Innovation Awards 2025: #2
Technical lead Johannes Petzoldt tells the story behind the development of Thermo’s Orbitrap Astral Zoom Mass Spectrometer
theanalyticalscientist.com
November 13, 2025 at 4:50 PM
Reposted by Hamish Stewart
pastelbio.bsky.social
Breaking barriers in crosslinking mass spectrometry with enhanced throughput and sensitivity using Orbitrap Astral www.nature.com/artic...

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#proteomics #prot-paper
November 11, 2025 at 6:40 PM
Reposted by Hamish Stewart
leecantrell.bsky.social
I'm excited to see this paper in press!

pubs.acs.org/doi/10.1021/...
Multiplexed Nanoparticle Protein Corona Enables Accurate and Precise Deep Plasma Proteomics
The Proteograph Product Suite, a multiplexed nanoparticle (NP) protein corona-based workflow, substantially improves the depth of detection of proteins by mass spectrometry (MS) by compressing the dyn...
pubs.acs.org
October 17, 2025 at 3:42 PM
Reposted by Hamish Stewart
baybioms.bsky.social
🧵(4/7)

🔬 We have put together a fascinating #Keynote #Speakers team:
• Prof. Albert Heck - @hecklab.bsky.social
• Dr. Hamish Stewart - @hamishs.bsky.social
• Prof. Olga Vitek - @olgavitek.bsky.social l
• Prof. Ron M.A. Heeren
October 15, 2025 at 5:18 AM
Reposted by Hamish Stewart
kmechtler.bsky.social
It is an honor to inform you that our manuscript with low resolution FAIMS is now online

www.biorxiv.org/content/10.1...
Low-resolution FAIMS for increased peptide coverage in low-load and single-cell proteomics
Field Asymmetric Ion Mobility Spectrometry (FAIMS) enhances signal to noise ratio filtering ions based on their differential mobility, making it an indispensable tool for single-cell and low-input pro...
www.biorxiv.org
August 28, 2025 at 1:01 PM
hamishs.bsky.social
👀 A simple optimization giving substantial benefits. A little like widening an over-tight quadrupole window to help transmission.
August 27, 2025 at 11:42 AM
hamishs.bsky.social
My great colleague Tabi is featured in JASMS. Check out his story.
August 16, 2025 at 2:08 PM
Reposted by Hamish Stewart
baybioms.bsky.social
🎉 BayBioMS turns 10! 🎉

2025 marks our 10th anniversary of Mapping Molecular Mountains.

Thus, we’re excited to invite you to the 10 Years of #BayBioMS #Symposium – a celebration of a decade of accelerating #MassSpectrometry research at the @tum.de!

🧵(1/6)
July 22, 2025 at 4:36 AM
Reposted by Hamish Stewart
jesperolsenlab.bsky.social
🚀 Check out our preprint on the new Thermo Scientific Orbitrap Astral Zoom MS 💫👇🏼

www.biorxiv.org/content/10.1...
Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technolo...
www.biorxiv.org
July 19, 2025 at 9:22 AM
Reposted by Hamish Stewart
jesperolsenlab.bsky.social
Boosting Orbitrap MS/MS speed to ∼70 Hz? 🚀

Read how we did it in our latest paper 👇

pubs.acs.org/doi/10.1021/...
Enhancing Tandem MS Sensitivity and Peptide Identification via Ion Preaccumulation in an Orbitrap Mass Spectrometer
High-throughput mass spectrometry-based proteomics has gained increasing interest for both academic and industrial applications. As implementation of faster gradients has facilitated higher sample thr...
pubs.acs.org
July 1, 2025 at 12:29 PM
Reposted by Hamish Stewart
rsc.org
🎉 Today we reveal the 2025 RSC Prize winners! 🎉

Celebrating excellence across research, diversity, tech roles, apprentices and partnerships. Join us in congratulating the remarkable individuals and teams advancing chemistry for society. buff.ly/K2un4O1 #Chemistry #ChemSky
Congratulations banner from the Royal Society of Chemistry featuring a medallion with symbolic icons representing various scientific elements and achievements, surrounded by a stardust background with the text "#RSCPrizes".
June 25, 2025 at 10:00 AM
Reposted by Hamish Stewart
cashwood.proteaglyco.com
Orbitrap Astral Team receive the RSC 2025 Analytical Science Horizon Prize: Robert Boyle Prize.

Interesting information about what each role does at TFS.

A good read:
www.rsc.org/standards-an...
June 25, 2025 at 11:43 AM
Reposted by Hamish Stewart
massspecpro.bsky.social
RIP Alan Marshall, one of the greatest mass spectrometrists ever, and a great human to boot.

nationalmaglab.org/careers/meet...
Alan Marshall: A scientist and a Gentleman - MagLab
Meet one of the greatest innovators in the history of mass spectrometry, hard at work.
nationalmaglab.org
June 12, 2025 at 2:03 PM
hamishs.bsky.social
Perfectly timed for the Orbitrap Astral Zoom launch today.
June 1, 2025 at 2:18 PM
Reposted by Hamish Stewart
jwoessmann.bsky.social
I am excited to share the first project of my PhD on bioRxiv and just in time for #ASMS2025 !
Increasing the sensitivity in single cell proteomics to quantify transcription factors in single hematopoietic stem and progenitor cells by iDIA.
www.biorxiv.org/content/10.1...
Informed Data-Independent Acquisition Enables Targeted Quantification of Key Regulatory Proteins in Cell Fate Decision at Single-Cell Resolution
Cellular differentiation processes are largely orchestrated by variation in transcription factor (TF) abundance. Since these proteins are usually expressed at extremely low levels, studying TF-driven ...
www.biorxiv.org
May 31, 2025 at 6:01 PM
Reposted by Hamish Stewart
erwinschoof.bsky.social
The Cell Diversity Lab is well represented at this year's ASMS; please come and talk with Jakob Woessmann and Benjamin Furtwängler to hear all about their latest efforts in improving, and applying single-cell proteomics by MS.

#singlecellproteomics #teammassspec #cellheterogeneity
May 31, 2025 at 10:55 AM
Reposted by Hamish Stewart
slavov-n.bsky.social
A new dimension for multiplexing mass spec analysis -- time -- is enabling scaling up throughput at new levels.

We demonstrate 27-plex DIA enabling over 500 samples / day.

We project that timePlex will enable throughputs exceeding 1,000 samples / day.

www.biorxiv.org/content/10.1...
May 28, 2025 at 10:32 AM
Reposted by Hamish Stewart
pastelbio.bsky.social
News in Proteomics Research blog post | MAP-MS! Get more Orbitrap dynamic range for free! proteomicsnews.blogs...

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#proteomics #prot-other
May 19, 2025 at 6:40 PM
Reposted by Hamish Stewart
pastelbio.bsky.social
Neil Kelleher: The Human Proteoform Project Could Transform Medicine theanalyticalscienti...

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#proteomics #prot-article
May 3, 2025 at 7:20 PM
Reposted by Hamish Stewart
joostsnijder.bsky.social
Excited to announce our revamped PhD-level BioMS course this September:

Advanced Proteomics for Drug Discovery and Biotherapeutics

Great line-up of instructors and topics, registration is open:
www.hecklab.com/advanced-pro...
April 29, 2025 at 9:32 AM
Reposted by Hamish Stewart
natmethods.nature.com
CHIMERYS is a spectrum-centric and data acquisition method-agnostic algorithm that deconvolves any MS2 spectrum, regardless of whether it was acquired by DDA, DIA or PRM, thus unifying analysis of bottom-up proteomics data.
@msaid-de.bsky.social @kusterlab.bsky.social www.nature.com/articles/s41...
April 22, 2025 at 5:12 PM