iamyourgasman.bsky.social
@iamyourgasman.bsky.social
Intensivist, researcher, dad, whippet slave, scuba diver (stupid depths on CCR), motorbike and heavy metal enthusiast.
Anyone else found themselves in a situation where you need to do an exam and it means you have to unlearn truth and readopt dogma to pass it? What’s the best approach? I can’t argue with a computer and an MCQ
November 27, 2024 at 6:41 PM
Reposted
Hey gang, it may still be 2024, but the portal is open to submit proposals for SCCM annual Congress in March of 2026. The window to submit closes January 31, 2025. Also a chance to reinstate your access since the software update at my.sccm.org #PedsICU
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my.sccm.org
November 22, 2024 at 4:25 PM
Hi folks, thanks for the follows! I’m finding out about this space and hope to build back the community we had before. Admittedly, the account will be quiet for the next few weeks as I have some stuff to deal with.
November 13, 2024 at 8:11 AM
Reposted
Global estimates of lives and life-years saved by COVID-19 vaccination during 2020-2024

Calculating the lives and life-years saved by COVID-19 vaccination worldwide from the onset of the vaccination campaigns until October 2024. Well, they work!!!

www.medrxiv.org/cont...
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Global estimates of lives and life-years saved by COVID-19 vaccination during 2020-2024
Estimating global lives and life-years saved is important to put into perspective the benefits of COVID-19 vaccination. Prior studies have focused mainly on the pre-Omicron period or only on specific regions, lack crucial life-year calculations, and often depend on strong modeling assumptions with unaccounted uncertainty. We aimed to calculate the lives and life-years saved by COVID-19 vaccination worldwide from the onset of the vaccination campaigns and until October 2024. We considered different strata according to age; community-dwelling and long-term care residence status; pre-Omicron and Omicron periods; and vaccination before and after a SARS-CoV-2 infection. In the main analysis, 2.533 million deaths were averted. Eighty-two percent were among people vaccinated before any infection, 57% were in the Omicron period, and 90% pertained to people 60 years and above. Sensitivity analyses suggested 1.4 to 4.0 million lives saved. Some sensitivity analyses showed preponderance of the benefit during the pre-Omicron period. We estimated 14.8 million life-years saved (sensitivity range, 7.4-23.6 million life-years). Most life-years saved (76%) were in people over 60 years old, but long-term care residents contributed only 2% of the total. Children and adolescents (0.01% of lives saved and 0.1% of life-years saved) and young adults 20-29 years old (0.07% of lives saved and 0.3% of life-years saved) had very small contributions to the total benefit. Based on a number of assumptions, these estimates are substantially more conservative than previous calculations focusing mostly on the first year of vaccination, but they still undeniably demonstrate a major overall benefit from COVID-19 vaccination during 2020-2024. The vast majority of benefit in lives and life-years saved was secured for a portion of the elderly minority of the global population. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement The study did not receive any funding ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes All data are in the manuscript
www.medrxiv.org
November 12, 2024 at 2:50 PM
Reposted
New paper from my group, led by Sam Lockhart in collaboration with Newport, Sunderland and Plymouth (co-authors not yet on BSky). Proning patients with severe CVOID-19 resulted in increased insulin requirements -against what we had hypothesised 🧪📟
#emimcc #AnSky #medsky #ICMSky

rdcu.be/dZVtr
Prone positioning is associated with increased insulin requirements in mechanically ventilated patients with COVID-19
Scientific Reports - Prone positioning is associated with increased insulin requirements in mechanically ventilated patients with COVID-19
eur03.safelinks.protection.outlook.com
November 12, 2024 at 9:41 AM