Marc Veldhoen
@marcveld.bsky.social
Professor of Immunology 🇳🇱 🇬🇧
Lisbon, 🇵🇹
#Immunology
Time for Science, not silence
https://scholar.google.co.uk/citations?user=7vG1jLIAAAAJ&hl=en
https://orcid.org/0000-0002-1478-9562
threads.net/@marc_veld
mastodon.online/@marc_veld
Lisbon, 🇵🇹
#Immunology
Time for Science, not silence
https://scholar.google.co.uk/citations?user=7vG1jLIAAAAJ&hl=en
https://orcid.org/0000-0002-1478-9562
threads.net/@marc_veld
mastodon.online/@marc_veld
Pinned
CovidDoom and antivax disinformation accounts thrive on fear. They claim science hides “the truth,” but offer no solid evidence of their own, only conjecture. By turning uncertainty into conspiracy, they erode trust in experts and data, making evidence itself seem suspicious.
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New research confirms HPV vaccination prevents cervical cancer
The findings show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes
www.cochrane.org/abo...
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The findings show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes
www.cochrane.org/abo...
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November 27, 2025 at 9:59 PM
New research confirms HPV vaccination prevents cervical cancer
The findings show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes
www.cochrane.org/abo...
1/5
The findings show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes
www.cochrane.org/abo...
1/5
Excellent post-doc postion available in Brazil. Good lab, nice place!
November 27, 2025 at 3:40 PM
Excellent post-doc postion available in Brazil. Good lab, nice place!
‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission
Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.
www.nature.com/artic...
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Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.
www.nature.com/artic...
1/2
‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission
Nature - Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.
www.nature.com
November 27, 2025 at 2:23 PM
‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission
Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.
www.nature.com/artic...
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Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.
www.nature.com/artic...
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Reposted by Marc Veldhoen
In the autumn of 2020, we completed our initial outlook on the developing COVID-19 pandemic caused by SARS-CoV-2. At that time, our laboratories were deeply embedded in a concerted national and international effort to understand the virus.
www.nature.com/artic...
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www.nature.com/artic...
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Endemic SARS-CoV-2 will maintain post-pandemic immunity | Nature Reviews Immunology
COVID-19 vaccinations have started. They will stop the pandemic. Citing recent data that are in line with immunological knowledge and predictions, combined with insights of common cold coronaviruses, we here set out the case that the maintenance of population immunity will not depend on continued vaccinations but on the endemic presence of SARS-CoV-2. Here, Veldhoen and Simas discuss why immunity to SARS-CoV-2 in populations may ultimately be driven by the endemic presence of the virus and not rely on continued mass vaccination programmes.
www.nature.com
November 26, 2025 at 7:05 AM
In the autumn of 2020, we completed our initial outlook on the developing COVID-19 pandemic caused by SARS-CoV-2. At that time, our laboratories were deeply embedded in a concerted national and international effort to understand the virus.
www.nature.com/artic...
1/4
www.nature.com/artic...
1/4
Can a virus reach the unborn? Yes, a virus can. An infamous example was the ZIKA virus epidemic. But, what about SARS-CoV-2? It seems it can.
Presence of SARS-CoV-2 in fetal organs via intraamniotic infection
www.nature.com/artic...
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Presence of SARS-CoV-2 in fetal organs via intraamniotic infection
www.nature.com/artic...
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Presence of SARS-CoV-2 in fetal organs via intraamniotic infection
Nature Communications - Infection with SARS-CoV-2 during pregnancy may result in maternal and fetal complications. Here, the authors analyze 18 fetuses following maternal SARS-CoV-2 infection and...
www.nature.com
November 27, 2025 at 2:04 PM
Can a virus reach the unborn? Yes, a virus can. An infamous example was the ZIKA virus epidemic. But, what about SARS-CoV-2? It seems it can.
Presence of SARS-CoV-2 in fetal organs via intraamniotic infection
www.nature.com/artic...
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Presence of SARS-CoV-2 in fetal organs via intraamniotic infection
www.nature.com/artic...
1/7
Reposted by Marc Veldhoen
The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective
A opinion piece pulling together several observations and hypothesis of the rise in LongCovid, not only involving SC2.
elifesciences.org/ar...
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A opinion piece pulling together several observations and hypothesis of the rise in LongCovid, not only involving SC2.
elifesciences.org/ar...
1/8
The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective
Unraveling mechanisms underlying post-acute SARS-CoV-2 sequelae (long COVID) and finding therapeutic solutions require a full understanding of the causative role of SARS-CoV-2 persistence and/or infection with other microorganisms, which may be pre-existing, concurrent, or subsequent to acute COVID-19.
elifesciences.org
November 18, 2025 at 5:54 PM
The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective
A opinion piece pulling together several observations and hypothesis of the rise in LongCovid, not only involving SC2.
elifesciences.org/ar...
1/8
A opinion piece pulling together several observations and hypothesis of the rise in LongCovid, not only involving SC2.
elifesciences.org/ar...
1/8
Reposted by Marc Veldhoen
Some seem to like this stuff. Of course, a like block is running on posts such as these.
November 26, 2025 at 9:48 PM
Some seem to like this stuff. Of course, a like block is running on posts such as these.
Reposted by Marc Veldhoen
November 26, 2025 at 7:30 PM
Reposted by Marc Veldhoen
Wastewater update, end of November 2025, the Netherlands.
SARS-CoV-2 levels are low is all there is.
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SARS-CoV-2 levels are low is all there is.
1/3
November 26, 2025 at 9:25 PM
Wastewater update, end of November 2025, the Netherlands.
SARS-CoV-2 levels are low is all there is.
1/3
SARS-CoV-2 levels are low is all there is.
1/3
Reposted by Marc Veldhoen
AID's role in class switch recombination & somatic hypermutation was published in @cellpress.bsky.social 25 years ago, a tour de force combo of mouse gene discovery & mechanistic work (Honjo lab) and human genetics (Durandy, Fischer et al).
What a privilege to write this with Sidonia & Masamichi
What a privilege to write this with Sidonia & Masamichi
Activation-induced cytidine deaminase: The missing piece of many puzzles
Twenty-five years ago, two Cell papers reported the key missing functional piece in
three molecular puzzles. The genetic swapping of immunoglobulin constant regions,
the mutational fine-tuning of anti...
www.cell.com
November 26, 2025 at 5:58 PM
AID's role in class switch recombination & somatic hypermutation was published in @cellpress.bsky.social 25 years ago, a tour de force combo of mouse gene discovery & mechanistic work (Honjo lab) and human genetics (Durandy, Fischer et al).
What a privilege to write this with Sidonia & Masamichi
What a privilege to write this with Sidonia & Masamichi
Reposted by Marc Veldhoen
Severe Infection Is Characterized by Prolonged Immune Activation
The authors compared the immune responses of infection-confirmed hospitalized individuals with severe acute respiratory illness (SARI) to those of nonhospitalized individuals with infection-like illness (ILI).
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The authors compared the immune responses of infection-confirmed hospitalized individuals with severe acute respiratory illness (SARI) to those of nonhospitalized individuals with infection-like illness (ILI).
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November 26, 2025 at 10:35 AM
Severe Infection Is Characterized by Prolonged Immune Activation
The authors compared the immune responses of infection-confirmed hospitalized individuals with severe acute respiratory illness (SARI) to those of nonhospitalized individuals with infection-like illness (ILI).
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The authors compared the immune responses of infection-confirmed hospitalized individuals with severe acute respiratory illness (SARI) to those of nonhospitalized individuals with infection-like illness (ILI).
1/7
Reposted by Marc Veldhoen
The ZeroCovid cult is severely damaging people's mental health and science. It is based on a severely incorrect interpretation of literature and knowledge of immunology and other infectious agents. This likely began out of fear during the pandemic.
February 27, 2025 at 11:21 PM
The ZeroCovid cult is severely damaging people's mental health and science. It is based on a severely incorrect interpretation of literature and knowledge of immunology and other infectious agents. This likely began out of fear during the pandemic.
Appeals court upholds $1M penalty against Trump over 'frivolous' Hillary Clinton lawsuit
The 11th U.S. Circuit Court of Appeals found that Trump and his attorneys had engaged in "sanctionable conduct" with their suit against Clinton and others.
The 11th U.S. Circuit Court of Appeals found that Trump and his attorneys had engaged in "sanctionable conduct" with their suit against Clinton and others.
Appeals court upholds $1M penalty against Trump over 'frivolous' Hillary Clinton lawsuit
The 11th U.S. Circuit Court of Appeals found that Trump and his attorneys had engaged in "sanctionable conduct" with their suit against Clinton and others.
www.nbcnews.com
November 26, 2025 at 10:13 PM
Appeals court upholds $1M penalty against Trump over 'frivolous' Hillary Clinton lawsuit
The 11th U.S. Circuit Court of Appeals found that Trump and his attorneys had engaged in "sanctionable conduct" with their suit against Clinton and others.
The 11th U.S. Circuit Court of Appeals found that Trump and his attorneys had engaged in "sanctionable conduct" with their suit against Clinton and others.
Reposted by Marc Veldhoen
The last of the Covidians
The emergency mindset drove them mad
A story that resounds, that is very recognisable. Incredibly sad, and sometimes so maddeningly frustrating.
unherd.com/2025/11/t...
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The emergency mindset drove them mad
A story that resounds, that is very recognisable. Incredibly sad, and sometimes so maddeningly frustrating.
unherd.com/2025/11/t...
1/6
November 25, 2025 at 10:50 PM
The last of the Covidians
The emergency mindset drove them mad
A story that resounds, that is very recognisable. Incredibly sad, and sometimes so maddeningly frustrating.
unherd.com/2025/11/t...
1/6
The emergency mindset drove them mad
A story that resounds, that is very recognisable. Incredibly sad, and sometimes so maddeningly frustrating.
unherd.com/2025/11/t...
1/6
Some seem to like this stuff. Of course, a like block is running on posts such as these.
November 26, 2025 at 9:48 PM
Some seem to like this stuff. Of course, a like block is running on posts such as these.
Reposted by Marc Veldhoen
The importance of excessive mortality assumptions...
Left hand plot: 2017-19 average used as baseline. Conclusion: Sweden is 'best' with negative excess mortality.
Right hand plot: 2017-19 linear trend extrapolated as baseline. Conclusion: Sweden is 'worst' with huge positive excess mortality.
Left hand plot: 2017-19 average used as baseline. Conclusion: Sweden is 'best' with negative excess mortality.
Right hand plot: 2017-19 linear trend extrapolated as baseline. Conclusion: Sweden is 'worst' with huge positive excess mortality.
November 16, 2025 at 12:51 PM
The importance of excessive mortality assumptions...
Left hand plot: 2017-19 average used as baseline. Conclusion: Sweden is 'best' with negative excess mortality.
Right hand plot: 2017-19 linear trend extrapolated as baseline. Conclusion: Sweden is 'worst' with huge positive excess mortality.
Left hand plot: 2017-19 average used as baseline. Conclusion: Sweden is 'best' with negative excess mortality.
Right hand plot: 2017-19 linear trend extrapolated as baseline. Conclusion: Sweden is 'worst' with huge positive excess mortality.
Wastewater update, end of November 2025, the Netherlands.
SARS-CoV-2 levels are low is all there is.
1/3
SARS-CoV-2 levels are low is all there is.
1/3
November 26, 2025 at 9:25 PM
Wastewater update, end of November 2025, the Netherlands.
SARS-CoV-2 levels are low is all there is.
1/3
SARS-CoV-2 levels are low is all there is.
1/3
Reposted by Marc Veldhoen
Science and activism are not the same. Science tests ideas with data, admits uncertainty, and evolves with evidence. Activism often seeks certainty, slogans, and easy explanations and enemies. The clash becomes clear when disagreement is met with insult, not argument.
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September 17, 2025 at 5:36 PM
Science and activism are not the same. Science tests ideas with data, admits uncertainty, and evolves with evidence. Activism often seeks certainty, slogans, and easy explanations and enemies. The clash becomes clear when disagreement is met with insult, not argument.
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November 26, 2025 at 7:30 PM
Indeed, SARS-CoV-2 does not damage the immune system. That is not what I am saying, it is what the data shows us, time and time again.
Such as here:
open.substack.com/pub/marcveld...
Such as here:
open.substack.com/pub/marcveld...
November 26, 2025 at 7:23 PM
Indeed, SARS-CoV-2 does not damage the immune system. That is not what I am saying, it is what the data shows us, time and time again.
Such as here:
open.substack.com/pub/marcveld...
Such as here:
open.substack.com/pub/marcveld...
Wow, some racism. That is always nice! Some swearing as well. That really does strengthen the argument....
And credentials.... yes, much needed to get to grips with a complex field. Zero what? Where does it state that... etc, etc.
This is emotion and victimhood over data, knowledge and facts.
And credentials.... yes, much needed to get to grips with a complex field. Zero what? Where does it state that... etc, etc.
This is emotion and victimhood over data, knowledge and facts.
November 26, 2025 at 7:20 PM
Wow, some racism. That is always nice! Some swearing as well. That really does strengthen the argument....
And credentials.... yes, much needed to get to grips with a complex field. Zero what? Where does it state that... etc, etc.
This is emotion and victimhood over data, knowledge and facts.
And credentials.... yes, much needed to get to grips with a complex field. Zero what? Where does it state that... etc, etc.
This is emotion and victimhood over data, knowledge and facts.
White House Defends Witkoff After Leak of Conversation With Russian Official
Special envoy reportedly coached Putin aide on dealing with Trump on Ukraine
www.wsj.com/politics...
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Special envoy reportedly coached Putin aide on dealing with Trump on Ukraine
www.wsj.com/politics...
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White House Defends Witkoff After Leak of Conversation With Russian Official
U.S. special envoy Steve Witkoff reportedly coached an aide to Russia’s leader on dealing with President Trump on Ukraine.
www.wsj.com
November 26, 2025 at 2:19 PM
White House Defends Witkoff After Leak of Conversation With Russian Official
Special envoy reportedly coached Putin aide on dealing with Trump on Ukraine
www.wsj.com/politics...
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Special envoy reportedly coached Putin aide on dealing with Trump on Ukraine
www.wsj.com/politics...
1/2
Reposted by Marc Veldhoen
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine | NEJM
Influenza remains a major health burden despite the use of licensed vaccines. Nucleoside-modified
messenger RNA (modRNA) influenza vaccines have shown promising immunogenicity against
influenza and...
www.nejm.org
November 26, 2025 at 11:56 AM
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8
Reposted by Marc Veldhoen
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine | NEJM
Influenza remains a major health burden despite the use of licensed vaccines. Nucleoside-modified
messenger RNA (modRNA) influenza vaccines have shown promising immunogenicity against
influenza and...
www.nejm.org
November 26, 2025 at 11:56 AM
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8
Yes, safe and effective! mRNA may be able to closely match influenza variant and vaccine.
www.nejm.org/doi/ful...
1/8