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Reposted by Jose A Escudero

Zeynep Baharoglu @zeynepbaharoglu.bsky.social · Sep 6

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters

Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.

www.science.org

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Melanie Blokesch @mblokesch.bsky.social · Sep 6

Excited to share my latest review, now published in the Royal Society theme issue on ‘The ecology and evolution of bacterial immune systems' (available OA):

Defence systems encoded by core genomic islands of seventh pandemic Vibrio cholerae royalsocietypublishing.org/doi/10.1098/...

Defence systems encoded by core genomic islands of seventh pandemic Vibrio cholerae | Philosophical Transactions of the Royal Society B: Biological Sciences

Vibrio cholerae, the causative agent of cholera, has triggered seven pandemics, with the seventh pandemic emerging in 1961. The success of seventh pandemic El Tor (7PET) V. cholerae as a human pathogen is linked to its acquisition of mobile genetic ...

royalsocietypublishing.org

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Jose A Escudero @jaescudero.bsky.social · Aug 30

A pleasure to read, as all Andreas Wagner’s books. They always shake some of the pillars that support my view of things.
I highly recommend reading all of them, especially to young scientists. In Sleeping beauties I particularly enjoyed the mix with neuropsychology.

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Sociedad Española de Bioquímica y Biología Molecular (SEBBM) @sebbm.bsky.social · Aug 26

El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis.

https://f.mtr.cool/rnstpoiucs

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Sociedad Española de Bioquímica y Biología Molecular (SEBBM) @sebbm.bsky.social · Aug 18

El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis.

https://f.mtr.cool/czgfpzevqu

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Zeynep Baharoglu @zeynepbaharoglu.bsky.social · Aug 5

Are Bacterial Processes Dependent on Global Ribosome Pausing Affected by tRNA Modification Defects? 🦠 =>processes evolutionarily tuned to be sensitive to translation speed eg: motility, iron homeostasis, leader peptide attenuation (ex: trp). #rnasky #microsky www.sciencedirect.com/science/arti...

Are Bacterial Processes Dependent on Global Ribosome Pausing Affected by tRNA Modification Defects?

By integrating a literature review with transcriptomic, proteomic, and phenotypic data from two model bacteria, Escherichia coli and Vibrio cholerae, …

www.sciencedirect.com

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Alvaro San Millan @sanmillan.bsky.social · Aug 4

Oxygen levels can affect how resistance genes work, impacting antibiotic efficacy. This can be relevant for the most used ones: for example, resistance to fosfomycin varies with oxygen.

Learn more in our latest paper 👉 bit.ly/3T8sdpp a work led by @jaescudero.bsky.social

#AntibioticResistance

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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · Jul 24

A 2 yr postdoc position at the Bacterial
Genome Plasticity Unit of the Institut Pasteur (Paris) led by @amazeld.bsky.social in collaboration with Pierre-Alexandre Kaminski, funded by the French National Research Agency 👇

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Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · Jul 25

🚨🚨 New paper in @narjournal.bsky.social! 🍾

Excludons are pairs of overlapping genes that block each other’s expression (basically, reverse operons).

We built a tool to identify them in bacterial genomes using transcriptomic data, in an awesome collab led by Iñigo Lasa and Álvaro San Martín.

👇

ExcludonFinder: mapping transcriptional overlaps between neighboring genes

Abstract. Bacteria regulate neighboring genes via overlapping transcription in untranslated regions (UTRs), forming excludons. This overlap leads to transc

academic.oup.com

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Jose A Escudero @jaescudero.bsky.social · Jul 23

Congrats Carlos!! Very nice!!!

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Alexander Harms @aharms485.bsky.social · Jul 22

When the MSc student of Enea @phagemuffin.bsky.social is working in a brewery... 🍺🧬

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Oded Rechavi @odedrechavi.bsky.social · Jul 22

A gym that you go to but instead of working out you write papers

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Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · Jul 22

Do plasmids evolve faster 🐇, slower 🐢, or just like chromosomes 🧬?

In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments!

👇 Check out all the details in Paula’s thread!

Hint: 🐇 (most of the time)

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Nandita Garud @nanditagarud.bsky.social · Jul 22

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

Garud Lab

garud.eeb.ucla.edu

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Tami Lieberman @contaminatedsci.bsky.social · Jul 22

We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome.

See thread for more information and reach out!

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Jose A Escudero @jaescudero.bsky.social · Jul 22

Enjoy! It is indeed an amazing place!

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Vaughn Cooper @vscooper.micropopbio.org · Jul 20

A #short about mirror bacteria in French with subtitles, except for me, by @leblob.bsky.social

youtube.com/shorts/i0N55...

Bactérie miroir : pourquoi elle inquiète autant ? #short #science

YouTube video by Le Blob

youtube.com

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Michael Brockhurst @brockhurstlab.bsky.social · Jul 18

This Craig Maclean guy looks like he’s going places, one to keep an eye on! 👀

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Jose A Escudero @jaescudero.bsky.social · Jul 18

Congrats! 🎉

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Jose A Escudero @jaescudero.bsky.social · Jul 18

At 43: having money.
At 45: publishing a first author paper
At 60: having sex.
At 70: having a drivers license.
At 75: having friends.
At 80: not wetting your pants.

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Jose A Escudero @jaescudero.bsky.social · Jul 18

I guess we will have to add a couple of lines to the joke on success:

At age 4 success is not wetting your pants.
At 12: having friends.
At 16: having a drivers license.
At 20: having sex.
At 23: publishing a 1st author paper
At 28: having money.

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Craig MacLean @craigmaclean.bsky.social · Jul 16

New paper with @rwheatley8.bsky.social and Cedric Lood

Actual title: Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy.

Sensationalist title: Plasmids carry useless genes

academic.oup.com/ismej/articl...

Chromosomal capture of beneficial genes drives plasmids toward ecological redundancy

Abstract. Plasmids are a ubiquitous feature of bacterial genomes, but the forces driving genes and phenotypes to become associated with plasmids are poorly

academic.oup.com

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Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · Jul 17

Super proud of the lab for their outstanding presentations at #FEMS2025 in Milano!

Science is better when you work with such a stellar team!🚀✨

@femsmicro.org

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Ana Elena Pérez-Cobas @anaelenaperezcobas.bsky.social · Jul 17

Proud of the talk of Iván Linares at the #FEMS2025 on hospital-associated microbiomes and its role on pathogens persistance 🦠 @femsmicro.org

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