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JAMA Network Open @jamanetworkopen.com · 14h

In patients with idiopathic recurrent #pericarditis, IL-1ra-abs were exclusively detected in patients with active recurrent pericarditis, suggesting transient IL-1ra autoimmunity is a feature of active recurrent pericarditis. ja.ma/3KHHOLx

JAMA Network Open @jamanetworkopen.com · 14h

#Medicaid patients face barriers scheduling outpatient referral visits even when accounting for other factors impacting access, particularly those not in a specific health system’s ACO. ja.ma/48mXhdR

JAMA Network Open @jamanetworkopen.com · 14h

Numerous and specialty-specific barriers hinder first-line treatment intensification for metastatic castration-sensitive prostate #cancer, and cross-specialty tumor boards are a promising solution to improve its uptake. ja.ma/46YXJfQ

JAMA Network Open @jamanetworkopen.com · 15h

In this economic evaluation of medically attended #norovirus episodes, the median cost was highest for norovirus episodes that required hospitalization compared with outpatient and ED episodes. ja.ma/43cIAqf

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JAMA Network Open @jamanetworkopen.com · 15h

Short-term multicancer screening trials may lead to meaningful reductions in late-stage #cancer incidence but only modest declines in mortality, with most impact driven by a few common cancers. ja.ma/46ZQzbg

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JAMA Network Open @jamanetworkopen.com · 15h

#Narcolepsy was not associated with increased all-cause or cause-specific mortality compared to matched controls/siblings in this study with 22-year follow-up. ja.ma/4nNvQic

Graph shows survival probability over time (years) for two cohorts: Cases (dark blue) and Controls (orange). Both start near 1.0, gradually decreasing, with Cases declining more sharply after 20 years. 'No. at risk' numbers are given.

JAMA Network Open @jamanetworkopen.com · 15h

Pregnancy preferences are strongly associated with incident pregnancy, but the extent to which individuals achieve their reproductive goals varies by age, parity, cohabitation, education, employment, and racial and ethnic identity. ja.ma/3KJKU1G

Histogram showing 'Participants, %' on the y-axis from 0 to 8 and 'DAP score' on the x-axis from 0 to 4. The bar heights generally increase with the DAP score, with a significant spike at DAP score 4.

JAMA Network Open @jamanetworkopen.com · 16h

Higher severity of exposure to dust and fumes at the World Trade Center sites was associated with increased lung #cancer incidence among responders more than a decade after the attacks. ja.ma/3VY4ycD

Graph showing cumulative hazard over time for mild, moderate, and severe exposure levels. The x-axis represents time since July 1, 2012, and the y-axis shows cumulative hazard. Severe exposure has the highest hazard.

JAMA Network Open @jamanetworkopen.com · 16h

RCT: A self-guided smartphone app was linked to fewer depressive symptoms in people with intellectual disabilities. ja.ma/3VZYzUL

Infographic on a self-help app for depression in people with intellectual disabilities. Study included 45 males and 54 females with mean age 34.8. Results showed the app reduced depressive symptoms.

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JAMA Network Open @jamanetworkopen.com · 1d

#Medicaid primary care practice–led ACOs were associated with increased perinatal office visits, and health system-managed ACOs were associated with increased receipt of timely postpartum visits and decreased prenatal ER visits. ja.ma/4oa7gYr

Four line graphs comparing medical outcomes from 2016-2020. The graphs show: A) mean number of office visits, B) mean number of ED visits, C) proportion of deliveries that were cesarean, and D) proportion of deliveries with timely postpartum visits.

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JAMA Network Open @jamanetworkopen.com · 1d

Among individuals with #MentalIllness symptoms seeking holy water treatment in Ethiopia, only 1 in 6 sought professional care, and this treatment gap was associated with sociocultural, economic, and systemic challenges. ja.ma/3KNthxX

Bar graph showing mental health care prevalence. Those who sought treatment: ~18%. Those who did not: ~82%. Y-axis: Prevalence, %. X-axis: "Mental health care treatment sought" and "Mental health care treatment not sought"

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JAMA Network Open @jamanetworkopen.com · 1d

Physicians with higher professionalism and communication ratings in residency received better patient experience survey responses in early unsupervised practice. ja.ma/46RMG9P

JAMA Network Open article: "Trainee-Physician Milestones Ratings and Patient Experience Surveys in Early Unsupervised Practice" by Jenny X. Chen, Deirdre Mylod, Yuezhou Jing, et al. Published online October 8, 2025.

JAMA Network Open @jamanetworkopen.com · 1d

Among US adults, immigrants with serious psychological distress who engaged in #PhysicalActivity had a lower risk of all-cause mortality compared to both inactive immigrants with distress and nonimmigrants. ja.ma/48fxDaW

Survival probability graph showing comparative trends for immigrants and non-immigrants, differentiated by SPA/IPA and presence/absence of SPD over 20 years.The No. at risk for each category is listed at different time intervals.

JAMA Network Open @jamanetworkopen.com · 1d

First-line gene therapy for children with spinal muscular atrophy was associated with fewer unsatisfactory clinical responses and less respiratory and nutritional support over time, with similar motor outcomes compared to those treated with nusinersen. ja.ma/4h5Brhk

The image contains multiple scatter plots comparing treatment groups over time. Plot A displays 'CHOP INTEND score evolution by DMT treatment group', contrasting three therapies. Plot B shows 'CHOP INTEND score evolution in 12 matched pairs'.

JAMA Network Open @jamanetworkopen.com · 1d

Older adults receiving federal housing assistance are less likely to be diagnosed with late-stage #cancers including breast, colorectal, and lung cancer, compared to individuals who received no assistance. ja.ma/3WqgpjU

Four bar graphs compare estimated probabilities for different cancers (breast, colorectal, NSCLC, prostate) across disease stages (in situ, local, regional, distant), differentiating between HUD-assisted and non-HUD-assisted cases.

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JAMA Network Open @jamanetworkopen.com · 1d

Among vulnerable populations in Lebanon facing multiple crises, food insecurity, lower wealth, and less education were associated with worse pain, self-rated health, and #depression, with additional differences by nationality and sex. ja.ma/4of6Tfv

Two line graphs show trends from June 2022 to July 2024. Graph A, "Food insecurity," shows percentage of participants fluctuating between 65% and 90%. Graph B, "Low wealth," shows participant percentages between 30% and 60%, peaking in April 2024.

JAMA Network Open @jamanetworkopen.com · 1d

RCT: Among adults aged 65 years or older in Hong Kong, use of a hybrid chatbot was associated with higher pneumococcal vaccination uptake and improved stage of change scores compared to use of a standard chatbot intervention. ja.ma/439EwqG

JAMA Network Open infographic about a hybrid chatbot to promote pneumococcal vaccination among older adults. The population was 161 men, 213 women. The rate of vaccination uptake for the stage change intervention was 29.4% vs 18.7% for standard intervention.

JAMA Network Open @jamanetworkopen.com · 1d

RCT: Open-label placebo treatment for #migraine was not associated with fewer #headache or migraine days, but was associated with improved pain-related disability, quality of life, and global patient-reported improvement compared to usual care. ja.ma/4709BhU

Infographic titled, "RCT: Open-Label Placebos as Adjunct for the Preventive Treatment of Migraine" shows study population was 17 men and 103 women. Findings show no significant decrease in MHD in the OLP group, compared to the TAU group.

JAMA Network Open @jamanetworkopen.com · 2d

Use of sugammadex during minimally invasive inguinal hernia repair was associated with a lower rate of postoperative urinary retention and shorter hospital stay compared to traditional reversal agents. ja.ma/4nN4sB6

JAMA Network Open article: "Sugammadex for Postoperative Urinary Retention in Minimally Invasive Inguinal Hernia Repair: A Nonrandomized Clinical Trial" by William R. Lorenz, Alexis M. Holland, Brittany S. Mead, et al. Published Oct 7, 2025.

JAMA Network Open @jamanetworkopen.com · 2d

Black adolescents, on average, reported experiencing 6 online race-related experiences per day and negative experiences were associated with poor #mentalhealth. ja.ma/42sLS8E

https://ja.ma/48SF0VZ

Adolescents’ Race-Related Online Experiences and Mental Health

ja.ma

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JAMA Network Open @jamanetworkopen.com · 2d

A two-stage screening of 754 preschoolers in Austria found 4.4% needing therapy for motor deficits and 2.1% with critical motor skills based on validated assessments, yet none of these children’s parents reported concerns. ja.ma/4o7E1FS

JAMA Network Open article: "Unrecognized Motor Difficulties and Developmental Coordination Disorder in Preschool Children" by Barbara Scheiber, Claudia Spiegl, Jasmin Plattner, et al. Published October 7, 2025.

JAMA Network Open @jamanetworkopen.com · 2d

A consensus identified six core competencies for #MedicalCannabis education in medical schools, covering pharmacology, legal issues, clinical evidence, risks, and management to address knowledge gaps and support informed patient care. ja.ma/3KCfU3G

JAMA Network Open article: "Developing Medical Cannabis Competencies: A Consensus Statement." By Yuval Zolotov, Leslie Mendoza Temple, Richard Isralowitz, et al. Published Oct 7, 2025.

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JAMA Network Open @jamanetworkopen.com · 2d

Most nonprotected class drugs with #FDA accelerated approval were covered by some #Medicare Part D plans, but fewer than half were widely available, and most coverage appeals were denied. ja.ma/42s1k4Q

Line graph shows the proportion of Medicare Part D plans over a decade. Several drugs are tracked including Deferiprone, Droxidopa, and Seladelpar. Droxidopa and Bedaquiline show a high proportion, while Seladelpar's proportion remains low.

JAMA Network Open @jamanetworkopen.com · 2d

Among primary care patients sending portal messages, physician response rates within 1 business day were lower for Black, Hispanic, dual-eligible, and Spanish-preferring patients compared to White, commercially insured, and English-preferring patients. ja.ma/46UaOY1

Three bar graphs show care team member response percentages, comparing race & ethnicity, insurance type, & primary language to response time in business days (1 vs. 3). Each graph displays varying response rates across categories.

JAMA Network Open @jamanetworkopen.com · 2d

TEM-AID, an #AI system for analyzing kidney TEM images, accurately segmented glomerular structures and outperformed pathologists in diagnosing glomerular disease subtypes. ja.ma/4mQIJXy

The image contains 5 plots: Prevalence of subtype by center, classification performance of TEM-AID system, confusion matrix of training/validation set, and precision in the Huayin validation set.