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JAMA Network Open
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JAMA Network Open is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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Applications are open for the JAMA Network Open Editorial Fellowship. From April 2026 to October 2027, Fellows will experience the publishing process firsthand, team up with experienced editors, & coauthor commentary.

🔗 Learn more: ja.ma/4qMquVI
January 12, 2026 at 12:30 PM
In Japan, telemedicine use remained below 1% of outpatient visits through 2024—even after pandemic-era deregulation—highlighting persistently low uptake and the need for greater clinician incentives and user support. ja.ma/49ptcJu
January 9, 2026 at 7:45 PM
Adoption of ambient #AI scribes was associated with small increases in weekly RVUs and encounters, without increased claim denials in an academic health system. ja.ma/4pzAZKV
January 9, 2026 at 7:30 PM
In a qualitative study of midlevel Asian faculty members at a large US academic medical center, participants described multifactorial barriers that impede leadership advancement. ja.ma/4jH62TO
January 9, 2026 at 7:15 PM
Over 2 years, both bariatric surgery and #GLP1RA treatment were associated with substantial fat mass loss, moderate fat-free mass loss, and increased FFM/FM ratio, with changes more pronounced after surgery. ja.ma/3YQSXxH
January 9, 2026 at 7:00 PM
Cluster RCT: A discharge-focused prospective audit and feedback intervention did not reduce overall antibiotic use at hospital discharge but improved optimal discharge prescribing for common infections; broader approaches are needed. ja.ma/49q5Nrh
January 9, 2026 at 6:45 PM
Higher neighborhood #PersistentPoverty was linked with increased mortality among Californians with colon cancer; this association was attenuated after accounting for guideline-concordant care, highlighting quality of care as a key mediator. ja.ma/3YAEwNY
January 9, 2026 at 6:30 PM
RCT: Metformin after antenatal betamethasone improved maternal glycemic control and reduced preterm neonatal hypoglycemia, indicating a safe and effective preventive approach. ja.ma/49tbogr
January 9, 2026 at 6:15 PM
RCT: Opportunistic #GenomicScreening for familial hypercholesterolemia + telegenetic counseling did not substantially lower #LDL_C at 6 months vs delayed results; further research is needed for clinical implementation. ja.ma/4jH5rBy
January 9, 2026 at 6:00 PM
Applications are open for the JAMA Network Open Editorial Fellowship. From April 2026 to October 2027, Fellows will experience the publishing process firsthand, team up with experienced editors, and coauthor commentary.

⏰ Apply before February 15
🔗 Learn more: ja.ma/49HLjLW
January 8, 2026 at 12:00 PM
Flavored #ECigarette bans were associated with reduced young adult initiation most among higher-income, non-Hispanic White groups, underscoring ongoing equity gaps in policy outcomes. ja.ma/4sItYdF
January 5, 2026 at 7:15 PM
Among women with #BreastCancer, incidence of persistent chemotherapy-induced alopecia was highest for Asian women and lowest in Hispanic or Latino and Black women. ja.ma/4soYk4n
January 5, 2026 at 7:00 PM
Among US clinicians treating #OpioidUseDisorder, 72% experienced difficulties starting buprenorphine in patients using fentanyl, leading 67% to alter standard induction practices. ja.ma/4jrhLFS
January 5, 2026 at 6:30 PM
Phase III RCT: Patients achieving pathological complete response after NCRT showed markedly improved survival in #EsophagealSquamousCellCarcinoma, supporting individualized approaches. ja.ma/3NaZxMD
January 5, 2026 at 6:15 PM
RCT: Smartphone-based ecological momentary assessment found greater morning fatigue but reduced afternoon and evening fatigue in patients with #Insomnia treated with suvorexant vs placebo. ja.ma/3LqjWN8
January 5, 2026 at 6:00 PM
Calling all early-career researchers! Applications for the JAMA Network Open Editorial Fellowship are now open.

From April 2026 to October 2027, Fellows will be mentored by editors, participate in the peer review process, and contribute to publications.

🔗 Apply by Feb. 15: ja.ma/4bgWSuT
January 5, 2026 at 2:00 PM
Hormonal contraceptive use was associated with lower odds of major adverse cardiovascular events in women, irrespective of depression or anxiety history, and with lower cardiovascular risk among women without PTSD, but not women with PTSD. ja.ma/3NrWeAL
January 3, 2026 at 5:00 PM
Timely MMR vaccine receipt decreased by 3 percentage points between 2021 and2024; the factors most strongly associated with not receiving MMR by 2 years of age were late receipt of standard 2- and 4-month vaccines. ja.ma/4jmLwHL
January 3, 2026 at 4:00 PM
RCT: Adding 1.5 g/d omega-3 to standard care did not improve depressive symptoms in children with moderate to severe major depressive disorder in Switzerland compared to placebo. ja.ma/4sjol5n
January 3, 2026 at 3:00 PM
LGBTQIA+ adults living in states that recently proposed or enacted LGBTQIA+-targeted policies reported profound and unequal impacts on their mental health due to these policies. ja.ma/49fhcKw
January 3, 2026 at 2:00 PM
Systematic review: Melatonin prescribing, extended use, and overdoses in children have increased in the past 20 years. 5 RCTs found that young children with autism fell asleep faster, but no RCT studied efficacy in children with typical development. ja.ma/45tLzf9
January 3, 2026 at 1:30 PM
Between 2011 and 2021, US preterm birth rates increased among households with incomes <200% of the federal poverty level, but remained stable among higher-income households. ja.ma/49iKrfn
January 3, 2026 at 1:00 PM
This study of US high school students found further evidence that bullying was associated with increased likelihood of suicide attempts, and that female students may be disproportionately affected by bullying. ja.ma/3Yme22E
January 3, 2026 at 12:30 PM
RCT: Infrapatellar fat pads steroid injections did not reduce pain or effusion in adults ≥45 years and older with inflammatory knee osteoarthritis in China compared to placebo injections. ja.ma/494Sg9V
January 3, 2026 at 12:00 PM
On Monday, JAMA Network Open will begin accepting applications for the 2026-2027 Editorial Fellowship. Gain insight into the publication process, collaborate with editors & participate in critical analysis of research manuscripts.

Bookmark the application, which is open Jan 5-Feb 15. ja.ma/4snameB
January 2, 2026 at 7:15 PM