jlawlab.bsky.social
@jlawlab.bsky.social
Reposted
Using CG methylation (mCG) of heterochromatic transposons as a trait for GWAS, we identified a major genetic association to an uncharacterized gene: a plant ortholog of vertebrate CDCA7.
November 7, 2025 at 5:05 PM
Have you ever wondered how new DNA methylation patterns are established?

Paradigm shift ahead! We discovered a new mode of DNA methylation targeting in plants that relies on transcription factors and sequence motifs rather than chromatin modifications to regulate the methylome. rdcu.be/eQ6L5
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December 11, 2025 at 9:56 PM
Reposted
Salk researchers are using a little flowering plant to answer the question: How do cells generate new epigenetic change? The answer marks a major shift in plant biology and may inform future epigenetic engineering strategies with medical and agricultural applications.

www.salk.edu/news-release...
Epigenetic changes regulate gene expression, but what regulates epigenetics? - Salk Institute for Biological Studies
LA JOLLA—All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are express...
www.salk.edu
November 21, 2025 at 11:14 PM
Reposted
Excited about the future of plant epigenetics?
Join us at the Keystone Symposium Plant Epigenetics & Epigenome Engineering in Fort Collins, October 13-16, 2025! keystonesymposia-19559593.hs-sites.com/%F0%9F%8C%BF...
Registration is open!
#PlantScience #Epigenetics #KeystoneSymposia
🌿 Join Us for Plant Epigenetics in Fort Collins! 🌿
http://keystonesymposia-19559593.hs-sites.com/🌿-join-us-for-plant-epigenetics-in-fort-collins-🌿-1
April 14, 2025 at 2:25 PM
Reposted
I'm thrilled to share that our study is now published in Cell:
Extensive N4 cytosine methylation is essential for Marchantia sperm function.
www.cell.com/cell/fulltex...
This paper confirms our 4mC discovery in Marchantia sperm and takes it much further.
A thread: 0/13
Extensive N4 cytosine methylation is essential for Marchantia sperm function
Global N4 cytosine methylation in Marchantia polymorpha sperm regulates gene expression and promotes sperm fertility.
www.cell.com
April 9, 2025 at 5:15 PM
Reposted
Excellent to see this amazing work out from James Walker and Xiaoqi Feng - amazing stuff!

Extensive N4 cytosine methylation is essential for Marchantia sperm function

www.cell.com/cell/fulltex...
Extensive N4 cytosine methylation is essential for Marchantia sperm function
Global N4 cytosine methylation in Marchantia polymorpha sperm regulates gene expression and promotes sperm fertility.
www.cell.com
April 10, 2025 at 12:31 AM