Katja Petzold
@katjapetzold.bsky.social
RNA moving faster than the blink of an eye! (By NMR) Professor @Uppsala University
More @ PetzoldLab.com
More @ PetzoldLab.com
Reposted by Katja Petzold
Our work presented today at the www.youtube.com/@CASPRNASIG online seminar! @bussigio.bsky.social will report on the #CASP16 solvation challenge and 2D ensemble reconstructions using #DMS data
CASP RNA SIG
Welcome nucleic acid enthusiasts to the Special Interest Group (SIG) focused different aspects of nucleic acid 3D structure prediction, including but not limited to obtaining experimental data, buildi...
www.youtube.com
October 30, 2025 at 2:45 PM
Our work presented today at the www.youtube.com/@CASPRNASIG online seminar! @bussigio.bsky.social will report on the #CASP16 solvation challenge and 2D ensemble reconstructions using #DMS data
Reposted by Katja Petzold
And don't forget, labs in the UK and Europe can donate to the Cambridge side of FlyBase through this link:
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
October 30, 2025 at 7:47 AM
And don't forget, labs in the UK and Europe can donate to the Cambridge side of FlyBase through this link:
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
Reposted by Katja Petzold
Competition @kaggle.com: Scientific Image Forgery Detection
Who can develop the best model to detect copy/move forgeries in biomedical images?
#ImageForensics
www.kaggle.com/competitions...
Who can develop the best model to detect copy/move forgeries in biomedical images?
#ImageForensics
www.kaggle.com/competitions...
Recod.ai/LUC - Scientific Image Forgery Detection
Develop methods that can accurately detect and segment copy-move forgeries within biomedical research images.
www.kaggle.com
October 23, 2025 at 6:46 PM
Competition @kaggle.com: Scientific Image Forgery Detection
Who can develop the best model to detect copy/move forgeries in biomedical images?
#ImageForensics
www.kaggle.com/competitions...
Who can develop the best model to detect copy/move forgeries in biomedical images?
#ImageForensics
www.kaggle.com/competitions...
Reposted by Katja Petzold
The adrenaline is still kicking from the incredible enthusiasm and support, everybody who invites a friend to try q.e.d today gets a free physiological relevance! 🍷
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 16, 2025 at 4:40 AM
The adrenaline is still kicking from the incredible enthusiasm and support, everybody who invites a friend to try q.e.d today gets a free physiological relevance! 🍷
Reposted by Katja Petzold
The following is REAL footage from Portland, 2025. Viewer discretion is advised.
October 9, 2025 at 8:23 PM
The following is REAL footage from Portland, 2025. Viewer discretion is advised.
When I learned about the cruelties of SS and Nazi's in school (I'm german) I always wondered, how this could happened... I never imagined seeing it happening again and getting the explanation in front of my eyes...
Sometimes we need a moment, but if you tune out completely, they win. Fascism doesn’t need your support, just your silence.
October 10, 2025 at 9:08 AM
When I learned about the cruelties of SS and Nazi's in school (I'm german) I always wondered, how this could happened... I never imagined seeing it happening again and getting the explanation in front of my eyes...
Reposted by Katja Petzold
Sometimes we need a moment, but if you tune out completely, they win. Fascism doesn’t need your support, just your silence.
October 10, 2025 at 2:31 AM
Sometimes we need a moment, but if you tune out completely, they win. Fascism doesn’t need your support, just your silence.
Do current publishing and carreer assessment practices limit scientific progress? Journals basically evaluate your recent citation numbers when you ausbmit to the editorial board...
HOWEVER: novel research areas have low number of participants and publications -> low number of citations
HOWEVER: novel research areas have low number of participants and publications -> low number of citations
October 10, 2025 at 9:03 AM
Do current publishing and carreer assessment practices limit scientific progress? Journals basically evaluate your recent citation numbers when you ausbmit to the editorial board...
HOWEVER: novel research areas have low number of participants and publications -> low number of citations
HOWEVER: novel research areas have low number of participants and publications -> low number of citations
It’s out :)
you thought it was weird for DNA to be 1% in a Hoogsteen base pair instead of a Watson-Crick-Franklin one?
Well there is more:
you thought it was weird for DNA to be 1% in a Hoogsteen base pair instead of a Watson-Crick-Franklin one?
Well there is more:
Check out our latest #NMR study together with @stonebutcher.bsky.social at @katjapetzold.bsky.social lab on an intermediate state of #DNA existing between the well-known Watson–Crick-Franklin and Hoogsteen base pairs stabilised by an anticancer drug Actinomycin D www.biorxiv.org/content/10.1...
1H R1ρ Relaxation Identifies a Hidden Intermediate in DNA Base-Pairing
1H R1ρ Relaxation dispersion (RD) NMR experiments provide valuable atomic-level insights into transient, high-energy conformational states of biomolecules. However, cross-relaxation artifacts can hamp...
www.biorxiv.org
October 7, 2025 at 7:09 AM
It’s out :)
you thought it was weird for DNA to be 1% in a Hoogsteen base pair instead of a Watson-Crick-Franklin one?
Well there is more:
you thought it was weird for DNA to be 1% in a Hoogsteen base pair instead of a Watson-Crick-Franklin one?
Well there is more:
Big thanks to my group of doing all this wonderful research 😍 and to @uu.se and my department IMBIM for nominating me and the Fernström price organization.
www.uu.se/en/news/2025...
www.uu.se/en/news/2025...
Eric K. Fernström Swedish Prize awarded to Katja Petzold
- Uppsala University
www.uu.se
September 25, 2025 at 12:50 PM
Big thanks to my group of doing all this wonderful research 😍 and to @uu.se and my department IMBIM for nominating me and the Fernström price organization.
www.uu.se/en/news/2025...
www.uu.se/en/news/2025...
Reposted by Katja Petzold
Core achievement unlocked!! Congrats to Fabrizio amd all authors!!
Who knew that the perfect pasta sauce could lead to a Nobel Prize? Congrats to ISTA postdoc Fabrizio Olmeda and collaborators for winning the Ig Nobel Prize with their research on mastering Cacio e Pepe. Bravo! 🍝 🎉
Getting hungry? Here´s the recipe for delicious research: https://bit.ly/42vlpHm
Getting hungry? Here´s the recipe for delicious research: https://bit.ly/42vlpHm
September 19, 2025 at 7:32 AM
Core achievement unlocked!! Congrats to Fabrizio amd all authors!!
please #NMR #RNA community, carefullly review papers! These are 2 blatantly manipulated papers that should have never gone through the peer-review system. Same for editors. If not us, who will stop this??
big thanks @elisabethbik.bsky.social 😍 without you we wouldn't have scienc left!
big thanks @elisabethbik.bsky.social 😍 without you we wouldn't have scienc left!
September 12, 2025 at 11:44 AM
please #NMR #RNA community, carefullly review papers! These are 2 blatantly manipulated papers that should have never gone through the peer-review system. Same for editors. If not us, who will stop this??
big thanks @elisabethbik.bsky.social 😍 without you we wouldn't have scienc left!
big thanks @elisabethbik.bsky.social 😍 without you we wouldn't have scienc left!
Reposted by Katja Petzold
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
September 9, 2025 at 12:10 PM
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
Reposted by Katja Petzold
#chemjobs #compchem
Assistant Professorship in Theoretical Chemistry at University of Cambridge
www.ch.cam.ac.uk/job/52637
Assistant Professorship in Theoretical Chemistry at University of Cambridge
www.ch.cam.ac.uk/job/52637
University Assistant Professor | Yusuf Hamied Department of Chemistry
Applications are invited for a University Assistant Professor to work in the area of theoretical chemistry, broadly defined, to be taken up in October 2026 (or earlier, by agreement). The successful a...
www.ch.cam.ac.uk
September 10, 2025 at 11:06 PM
#chemjobs #compchem
Assistant Professorship in Theoretical Chemistry at University of Cambridge
www.ch.cam.ac.uk/job/52637
Assistant Professorship in Theoretical Chemistry at University of Cambridge
www.ch.cam.ac.uk/job/52637
@rfsu.bsky.social
For all Swedes: please sign this petition, so our kids also have in the future SexEd in school.
Thanks!
www.rfsu.se/engagera-dig...
For all Swedes: please sign this petition, so our kids also have in the future SexEd in school.
Thanks!
www.rfsu.se/engagera-dig...
Rädda sexualundervisningen! | RFSU
www.rfsu.se
September 11, 2025 at 1:48 AM
@rfsu.bsky.social
For all Swedes: please sign this petition, so our kids also have in the future SexEd in school.
Thanks!
www.rfsu.se/engagera-dig...
For all Swedes: please sign this petition, so our kids also have in the future SexEd in school.
Thanks!
www.rfsu.se/engagera-dig...
Reposted by Katja Petzold
Check out our new method for targeted DNP-enhanced NMR of RNA using site-directed spin labeling, now live as a preprint on ChemRxiv:
doi.org/10.26434/che...
A fruitful collaboration with my colleague @rubindg.bsky.social and the group of Prof. Snorri Th. Sigurdsson from the University of Iceland.
doi.org/10.26434/che...
A fruitful collaboration with my colleague @rubindg.bsky.social and the group of Prof. Snorri Th. Sigurdsson from the University of Iceland.
September 8, 2025 at 2:49 PM
Check out our new method for targeted DNP-enhanced NMR of RNA using site-directed spin labeling, now live as a preprint on ChemRxiv:
doi.org/10.26434/che...
A fruitful collaboration with my colleague @rubindg.bsky.social and the group of Prof. Snorri Th. Sigurdsson from the University of Iceland.
doi.org/10.26434/che...
A fruitful collaboration with my colleague @rubindg.bsky.social and the group of Prof. Snorri Th. Sigurdsson from the University of Iceland.
New preprint out!
We introduce an AsymPol spin labeling for RNA, enabling targeted DNP NMR with up to 27× sensitivity boost at low concentrations.
Read here: chemrxiv.org/engage/chemr...
#RNA #NMR #DNP #StructuralBiology #SpinLabeling #ChemRxiv
We introduce an AsymPol spin labeling for RNA, enabling targeted DNP NMR with up to 27× sensitivity boost at low concentrations.
Read here: chemrxiv.org/engage/chemr...
#RNA #NMR #DNP #StructuralBiology #SpinLabeling #ChemRxiv
Site-Directed Spin Labeling with the Bis-Nitroxide AsymPol Enables Targeted DNP MAS NMR of RNA
Dynamic nuclear polarization (DNP) enhances NMR sensitivity by transferring electron spin polarization to nuclei, providing structural and biophysical insights into complex biomolecules at low concent...
chemrxiv.org
September 9, 2025 at 7:07 AM
New preprint out!
We introduce an AsymPol spin labeling for RNA, enabling targeted DNP NMR with up to 27× sensitivity boost at low concentrations.
Read here: chemrxiv.org/engage/chemr...
#RNA #NMR #DNP #StructuralBiology #SpinLabeling #ChemRxiv
We introduce an AsymPol spin labeling for RNA, enabling targeted DNP NMR with up to 27× sensitivity boost at low concentrations.
Read here: chemrxiv.org/engage/chemr...
#RNA #NMR #DNP #StructuralBiology #SpinLabeling #ChemRxiv
I am looking at a publication and wonder if some of the images are manipulated/manifactured. Does anyone have a good image checking tool? In days of AI such a thing should exist...
(me: academic in Sweden, if that helps with licenses)
THANKS!
(me: academic in Sweden, if that helps with licenses)
THANKS!
August 15, 2025 at 7:20 AM
I am looking at a publication and wonder if some of the images are manipulated/manifactured. Does anyone have a good image checking tool? In days of AI such a thing should exist...
(me: academic in Sweden, if that helps with licenses)
THANKS!
(me: academic in Sweden, if that helps with licenses)
THANKS!
What #biophysical process steers one #microRNA to select one #mRNA over another? Trying to decipher this for miR-34a: our long standing efforts with the labs of @anderssonlab.bsky.social and Alan Chen (SUNY RNA) are finally out:
academic.oup.com/nar/article/...
Thanks for the exciting journey 🤩😍
academic.oup.com/nar/article/...
Thanks for the exciting journey 🤩😍
Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy
Abstract. MicroRNAs (miRs) regulate gene expression post-transcriptionally by guiding Argonaute (AGO) proteins to target mRNAs. Efficiently predicting the
academic.oup.com
August 1, 2025 at 5:09 PM
What #biophysical process steers one #microRNA to select one #mRNA over another? Trying to decipher this for miR-34a: our long standing efforts with the labs of @anderssonlab.bsky.social and Alan Chen (SUNY RNA) are finally out:
academic.oup.com/nar/article/...
Thanks for the exciting journey 🤩😍
academic.oup.com/nar/article/...
Thanks for the exciting journey 🤩😍
Very interesting paper: RNA adjusting to starvation
Cells resist starvation through a nutrient stress splice switch
Abstract. Introns are common features of eukaryotic genes, typically removed through splicing to produce functional RNAs. In yeast, some introns play roles
academic.oup.com
June 27, 2025 at 5:36 AM
Very interesting paper: RNA adjusting to starvation
Reposted by Katja Petzold
While this paper looks interesting, let me just say (again) that (essentially all) NMR ensembles in the PDB are NOT thermodynamic ensembles or meant to represent these. They are "uncertainty ensembles" and using them to benchmark machine learning (or other) models of dynamics is not a good idea.
May 4, 2025 at 2:58 PM
While this paper looks interesting, let me just say (again) that (essentially all) NMR ensembles in the PDB are NOT thermodynamic ensembles or meant to represent these. They are "uncertainty ensembles" and using them to benchmark machine learning (or other) models of dynamics is not a good idea.
yeah! our paper is out! Congratulations to David and Emma 🥳
Excited to share our latest work, published today in Nucleic Acids Research:
"Mapping effective microRNA pairing beyond the seed using abasic modifications" - led by a former PhD student, now graduate of the lab, Dr David Kosek, in collaboration with Katja Petzold.
👉 doi.org/10.1093/nar/...
"Mapping effective microRNA pairing beyond the seed using abasic modifications" - led by a former PhD student, now graduate of the lab, Dr David Kosek, in collaboration with Katja Petzold.
👉 doi.org/10.1093/nar/...
Mapping effective microRNA pairing beyond the seed using abasic modifications
Abstract. MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by base-pairing to complementary sites in messenger RNAs (mRNAs). The p
doi.org
May 5, 2025 at 11:35 AM
yeah! our paper is out! Congratulations to David and Emma 🥳
Want to work in amazing environment? I moved to my current place two years and I couldn't be happier!
We are looking for a Associate Professor (wit possibility to promotion to Full Professor)
We are looking for a Associate Professor (wit possibility to promotion to Full Professor)
Senior lecturer in medical biochemistry - Uppsala University
Senior lecturer in medical biochemistry , Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University
www.uu.se
April 28, 2025 at 2:21 PM
Want to work in amazing environment? I moved to my current place two years and I couldn't be happier!
We are looking for a Associate Professor (wit possibility to promotion to Full Professor)
We are looking for a Associate Professor (wit possibility to promotion to Full Professor)
Lab alumnus Marvin Albers is going places! Congratulations 🤩
Marvin Albers and Tom Grossmann (Vrije Universiteit Amsterdam)Marvin Albers and Tom Grossmann (Vrije Universiteit Amsterdam) – IXA
www.ixa.nl
April 25, 2025 at 11:40 AM
Lab alumnus Marvin Albers is going places! Congratulations 🤩