Koen Raijer
@koenraijer.com
Psychiatry resident @ Reinier van Arkel & PhD candidate @ Maastricht University. Personalized psychopathology for psychotrauma. To measure or not to measure?
Also opened a pull request for it, I doubt it’ll ever get merged but we’ll see
February 16, 2025 at 9:35 PM
Also opened a pull request for it, I doubt it’ll ever get merged but we’ll see
Massive mechanistic blind spot: all diabetics have hyperglycemia but need diff drugs for type 1 vs 2 (we know why), but psychiatric drug treatment works only when the drug mechanism happens to match the person's unknown pathophysiology. This dilutes effect sizes in clinical trials.
February 13, 2025 at 7:02 PM
Massive mechanistic blind spot: all diabetics have hyperglycemia but need diff drugs for type 1 vs 2 (we know why), but psychiatric drug treatment works only when the drug mechanism happens to match the person's unknown pathophysiology. This dilutes effect sizes in clinical trials.
“Simulations break reality into chunks, as many as possible, but always too few”, from James Gleick's book "Chaos".
February 10, 2025 at 11:42 AM
“Simulations break reality into chunks, as many as possible, but always too few”, from James Gleick's book "Chaos".
Reposted by Koen Raijer
This machine does 75% of your PhD for you
January 15, 2025 at 2:04 PM
This machine does 75% of your PhD for you
I attended it online! Was just thinking about your question. I believe it was on how mechanistic explanations could fit in between network nodes? What would your answer be?
January 30, 2025 at 2:34 PM
I attended it online! Was just thinking about your question. I believe it was on how mechanistic explanations could fit in between network nodes? What would your answer be?
Sobering insider view on the whole deepseep affair
These four points on DeepSeek seem very likely correct and important to understand about the economics of building AI models and what DeepSeek actually did, from the CEO of Anthropic. darioamodei.com/on-deepseek-...
January 30, 2025 at 9:02 AM
Sobering insider view on the whole deepseep affair
Did you know the number of ways someone could be classified with PTSD according to the DSM-V is 636,120? (Galatzer-Levy & Bryant, 2013) doi.org/10.1177/1745...
636,120 Ways to Have Posttraumatic Stress Disorderheaderheaderfooter
doi.org
January 29, 2025 at 9:55 AM
Did you know the number of ways someone could be classified with PTSD according to the DSM-V is 636,120? (Galatzer-Levy & Bryant, 2013) doi.org/10.1177/1745...
What on earth is art and booksky doing there
January 28, 2025 at 11:05 PM
What on earth is art and booksky doing there
Fascinating technical perspective on #deepseek: speed of AI development may cascade because developing state-of-the-art models is again in reach of regular folk in academia
youtu.be/gY4Z-9QlZ64
youtu.be/gY4Z-9QlZ64
DeepSeek is a Game Changer for AI - Computerphile
YouTube video by Computerphile
youtu.be
January 28, 2025 at 10:37 PM
Fascinating technical perspective on #deepseek: speed of AI development may cascade because developing state-of-the-art models is again in reach of regular folk in academia
youtu.be/gY4Z-9QlZ64
youtu.be/gY4Z-9QlZ64
There’s a crazy amount of cringy sludge on bluesky that I almost suspect is AI-generated?
January 28, 2025 at 6:36 PM
There’s a crazy amount of cringy sludge on bluesky that I almost suspect is AI-generated?
"If you have a strong reaction to either the sentence: `I'm a normal human.` or `I'm not a normal human.` that means that you probably have an issue worth addressing in detail." (source: arc.net/l/quote/goce...)
Quote from “Useful Personality Tests — LessWrong”
arc.net
January 28, 2025 at 4:02 PM
"If you have a strong reaction to either the sentence: `I'm a normal human.` or `I'm not a normal human.` that means that you probably have an issue worth addressing in detail." (source: arc.net/l/quote/goce...)
Lovely explorable I just dug up from my complex systems course in uni about how simple rules for birds can lead to beautiful and complex flocking behavior: www.complexity-explorables.org/explorables/...
Flock'n Roll
Collective Behavior - Schooling Fish & Flocking Birds
www.complexity-explorables.org
January 28, 2025 at 12:23 PM
Lovely explorable I just dug up from my complex systems course in uni about how simple rules for birds can lead to beautiful and complex flocking behavior: www.complexity-explorables.org/explorables/...
Jpegmafia performing call me maybe @ @tivolivredenburg.bsky.social
January 27, 2025 at 10:21 PM
Jpegmafia performing call me maybe @ @tivolivredenburg.bsky.social
"People who view intelligence to be malleable believe that mistakes represent learning opportunities, whereas individuals who view intelligence as immutable believe mistakes are threatening to their identity" (Burnette et al., 2013)
January 27, 2025 at 2:13 PM
"People who view intelligence to be malleable believe that mistakes represent learning opportunities, whereas individuals who view intelligence as immutable believe mistakes are threatening to their identity" (Burnette et al., 2013)
Voordeel van samenwonen (met een vrouw): mijn neus wordt verrast door allerlei lekkere geurtjes
January 25, 2025 at 12:06 PM
Voordeel van samenwonen (met een vrouw): mijn neus wordt verrast door allerlei lekkere geurtjes
The #biopsychosocial model only makes sense as a layered structure, not as a venn diagram. Social emerges out of psycho emerges out of bio.
January 25, 2025 at 12:05 AM
The #biopsychosocial model only makes sense as a layered structure, not as a venn diagram. Social emerges out of psycho emerges out of bio.
Perhaps only local pockets of meaningful variance can be found in psychopathology networks? For a specific clinician-client combo in their joint sociocultural context
January 23, 2025 at 11:22 AM
Perhaps only local pockets of meaningful variance can be found in psychopathology networks? For a specific clinician-client combo in their joint sociocultural context
De Nieuwe #Stoffenwet verbiedt 3 stofgroepen: synthetische opioïden (afgeleiden van 4-aminopiperidine), synthetische cannabinoïden, en afgeleiden van 2-fenethylamine. Onder de streep een goede zaak; 2CB-analogen daargelaten allemaal stoffen met een zeer hoog misbruikgehalte.
January 21, 2025 at 7:13 AM
De Nieuwe #Stoffenwet verbiedt 3 stofgroepen: synthetische opioïden (afgeleiden van 4-aminopiperidine), synthetische cannabinoïden, en afgeleiden van 2-fenethylamine. Onder de streep een goede zaak; 2CB-analogen daargelaten allemaal stoffen met een zeer hoog misbruikgehalte.
Ladder sets involve starting at 1 rep, resting 15-30s, doing 2 reps, resting 15-30s, doing 3 reps, resting 15-30s, etc. Keep climbing until you fail, then start over at 1. Pull-ups work well here.
November 21, 2024 at 8:39 PM
Ladder sets involve starting at 1 rep, resting 15-30s, doing 2 reps, resting 15-30s, doing 3 reps, resting 15-30s, etc. Keep climbing until you fail, then start over at 1. Pull-ups work well here.
Myo-reps involve doing an activation set where you leave 1-2 reps in the tank. Then bang out 3-5 mini-sets of 3-5 reps. Rest 15 sec between each.
November 21, 2024 at 8:39 PM
Myo-reps involve doing an activation set where you leave 1-2 reps in the tank. Then bang out 3-5 mini-sets of 3-5 reps. Rest 15 sec between each.
Antagonistic supersets involve pairing opposing muscle groups with minimal rest in between. Examples: pull-ups + dips, bench press + rows, curls + tricep extensions. Saves time and gets you a better pump.
November 21, 2024 at 8:39 PM
Antagonistic supersets involve pairing opposing muscle groups with minimal rest in between. Examples: pull-ups + dips, bench press + rows, curls + tricep extensions. Saves time and gets you a better pump.