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kraftlabfr.bsky.social
Claudine Kraft's Lab
@kraftlabfr.bsky.social
240 followers 130 following 26 posts
Research group led by Claudine Kraft at the @UniFreiburg Our focus is on understanding the molecular mechanisms of #yeast and #mammalian #autophagy. Profile run by Riccardo.
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Jan 7
🚨 Paper Alert! We’re starting off the year with our latest publication in @naturecellbiology.bsky.social on the role of phase separation in selective autophagy initiation!
This work was a close and exciting collaboration with
@wilflinglab.bsky.social

🔗 nature.com/articles/s41...
Here's a thread👇
Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy - Nature Cell Biology
Licheva, Pflaum, Babic, Mancilla et al. show that low-affinity cargo–receptor interactions promote autophagy receptor mobility and condensation of the scaffold protein Atg11 to trigger initiation hub ...
nature.com
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · 13d
Back from the 8th NAS Conference in Sånga Säby, and what a wonderful experience it was! Christoph and Franzi represented the lab, and as a cherry on top, Chris won an award for his talk 🎉 Huge thanks to the NAS for organising and always creating such a warm community atmosphere!
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Reposted by Claudine Kraft's Lab
kleinevehnlab.bsky.social
KleineVehnLab @kleinevehnlab.bsky.social · 17d
The future of @cibss.bsky.social @uni-freiburg.de is about teamwork, curiosity, and collaboration across disciplines.

We are thrilled to be in this together @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social !
selfie of @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social
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Reposted by Claudine Kraft's Lab
cibss.bsky.social
CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social · 18d
New leadership for #CIBSS!
Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte.
More info: kurzlinks.de/fkv4
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elias-adriaenssens.bsky.social
Elias Adriaenssens @elias-adriaenssens.bsky.social · Jul 25
And it's out!

I'm thrilled to share our new paper (Adriaenssens et al., Nat Cell Biol 2025).

This paper describes a new mechanism for the initiation of autophagosome biogenesis.

We found that this WIPI-ATG13-driven pathway is preferentially used by a group of transmembrane autophagy receptors.
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Jul 30
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Jul 30
🎓✨ Huge congratulations to Saskia, an amazing PhD student who just successfully defended her thesis!
The flower crown toss might just become our new lab tradition! @uni-freiburg.de
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Jul 1
🧬 Excited to share this new publication! A collaborative effort within @sfb1381.bsky.social exploring the intersection of immunology and autophagy.

📖 Read it here: www.embopress.org/doi/full/10....
LRBA deficiency impairs autophagy and contributes to enhanced antigen presentation and T-cell dysregulation | EMBO reports
imageimageLRBA regulates autophagy and antigen presentation, shedding light on the mechanism of immune dysregulation in LRBA deficiency. LRBA directly interacts with PIK3R4 and FYCO1, promoting autop...
www.embopress.org
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Reposted by Claudine Kraft's Lab
uni-freiburg.de
Universität Freiburg @uni-freiburg.de · Jun 17
Die @dfg.de fördert drei Graduiertenkollegs „FORSCALE“, „Analysis nichtlinearer PDG“ und „ProtPath“ an der #UniFreiburg. Dieser Erfolg stärkt die #Spitzenforschung und #Nachwuchsförderung in Freiburg in #Forstwissenschaften, #Biochemie und #Mathematik. ➡️ ufr.link/dfg-grk-2025 #DFG
Prof. Dr. Thomas Seifert, Professor für Waldwachstum und Dendroökologie und Sprecher des IGK FORSCALE, Prof. Dr. Patrick Dondl, Professor für Angewandte Mathematik und Sprecher des IGK 3132 und Prof. Dr. Thomas Reinheckel, Professor für Molekulare Medizin / Zelluläre Pathomechanismen und Sprecher von ProtPath.
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ealmacellas.bsky.social
Eugenia Almacellas @ealmacellas.bsky.social · Jun 3
Excited to share our newly published work on ATG9A — this time focusing on its role at the lysosome. Discover how ARFIP2 and ATG9A coordinate PI4P regulation during lysosomal repair!

Congrats to all the authors, and special thanks to @stedet.bsky.social & @satooze.bsky.social !!

📜 bit.ly/43EbrDo
ATG9A and ARFIP2 cooperate to control PI4P levels for lysosomal repair
Lysosome damage activates multiple pathways to prevent lysosome-dependent cell death, including a repair mechanism involving endoplasmic reticulum (ER…
bit.ly
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Reposted by Claudine Kraft's Lab
envmet.bsky.social
Andreas Christen @envmet.bsky.social · May 24
Celebrating our successful new excellence cluster #FutureForests @uni-freiburg.de. Thanks @dfg.de, this will enable us to substantially invest in exciting and much-needed research for the next 7 years - predicting and transforming forest systems in a changing climate uni-freiburg.de/futureforest...
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uni-freiburg.de
Universität Freiburg @uni-freiburg.de · May 22
🎉Ab 1. Januar 2026 fördert die @dfg.de (#DFG) zwei #Exzellenzcluster der #UniFreiburg. Der bisherige #Exzellenzcluster @cibss.bsky.social wird weitere sieben Jahre fortgesetzt. Zudem startet der neue Exzellenzcluster #FutureForests. ufr.link/exzellenzclu...
Gruppenfoto: 1. Reihe v.l.n.r. Prof. Dr. Wolfgang Driever (CIBSS), Prof. Dr. Kerstin Kriegstein (Rektorin), Prof. Dr. Stefan Rensing (Prorektor für Forschung und Innovation), Prof. Dr. Jürgen Bauhus (Future Forests) 2. Reihe v.l.n.r. Prof. Dr. Jürgen Kleine-Vehn (CIBSS), Dr. Carola Hunte (CIBSS), Prof. Dr. Friederike Lang (Future Forests) 3. Reihe v.l.n.r. Prof. Dr. Claudine Kraft (CIBSS), Prof. Dr. Marc Hanewinkel (Future Forests) Fotograf: Michael Spiegelhalter
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · May 23
Thrilled to announce that our Cluster of Excellence CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social will continue to receive funding for another seven years! We’re happy to be part of such a great team!
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cibss.bsky.social
CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social · May 22
We are thrilled to have just found out: CIBSS has secured continued funding under the #ExcellenceStrategy! This major boost will enable us to accelerate our research into biological signalling and lay the groundwork for next-generation insights from 2026 to 2032!
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sfb1381.bsky.social
SFB 1381 - Protein Machineries @sfb1381.bsky.social · May 15
From May 5–8, 2025, the Cryo EM facility of #unifreiburg hosted an introductory workshop supported by SFB 1381 to learn how to access and use this cutting-edge technology. Hands-on sessions covered everything from sample prep to data analysis. Big thanks to the facility!
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womeninautophagy.bsky.social
Women in Autophagy @womeninautophagy.bsky.social · May 12
📆Join us this Wednesday, May 14th at 10:00 AM EST (NY Time) as Drs. Licheva, Babic, and Mancilla present their recent work:

"Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy"

🔗Zoom Info: Contact [email protected]

We look forward to seeing you there!
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Reposted by Claudine Kraft's Lab
sfb1381.bsky.social
SFB 1381 - Protein Machineries @sfb1381.bsky.social · Apr 24
Our 'SFB 1381's Female Minds' series has officially kicked off! Visit our website to read the first feature, introducing our SFB 1381 Principal Investigator Claudine Kraft:
www.sfb1381.uni-freiburg.de/sfb-1381s-fe...

@kraftlabfr.bsky.social
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Apr 15
Women in Autophagy is hosting their 6th Annual Symposium Webinar. Highly recommended for anyone interested in autophagy. #Autophagy #WomenInScience
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Apr 2
Happy to have participated in the #FCQC2025 in Frankfurt last week. Great to connect with others in the field and hear about exciting work. Thanks to the organizers for putting it together.
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ibc2-gu.bsky.social
IBC2 @ibc2-gu.bsky.social · Mar 26
🤩 2nd day of #FCQC2025 conference in Frankfurt was filled with inspiring lectures, vibrant discussions, great posters and a lot of joy of meeting colleagues from all over the world! A huge thanks to all organizers & supporters!
@goetheuni.bsky.social @sfb1177.bsky.social @proxidrugs.bsky.social
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ibc2-gu.bsky.social
IBC2 @ibc2-gu.bsky.social · Mar 24
Great kick off of our #FCQC2025! Looking forward to the next days full of inspiring sessions, meaningful conversations, and exciting new connections 🙌

@sfb1177.bsky.social @enablefrankfurt.bsky.social @proxidrugs.bsky.social @goetheuni.bsky.social
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lifesciswitzerland.bsky.social
Life Sciences Switzerland (LS2) @lifesciswitzerland.bsky.social · Mar 14
If you are interested in apoptosis, metabolism, cell death and autophagy, join the Swiss Apoptosis & Autophagy Meeting 2025 on September 4-5, at the Institute of Tissue Medicine and Pathology in Bern.

Submit your abstract until June 20: meetings.ls2.ch/sa2m-2025

‼️ Registration is free for all‼️
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Mar 12
🔄 Repost because the previous link was broken! To degrade or not to degrade! We put together an Autophagic Punctum with @wilflinglab.bsky.social on our latest paper, take a look if you're interested!
🔗 www.tandfonline.com/doi/full/10....
To degrade or not to degrade: how phase separation modulates selective autophagy
Selective macroautophagy/autophagy relies on newly formed double-membrane compartments, known as phagophores, to sequester and recycle diverse cellular components, including organelles, biomolecula...
www.tandfonline.com
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Mar 10
To degrade or not to degrade! We put together an Autophagic Punctum with @wilflinglab.bsky.social on our latest paper, take a look if you're interested!
🔗 www.tandfonline.com/doi/full/10....
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cibss.bsky.social
CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social · Mar 7
It’s #InternationalWomensDay tomorrow!
We took the occasion to talk to molecular biologist & CIBSS leadership team member @kraftlabfr.bsky.social about #Equality, #CultureChange and the power of mentoring and supportive networks in science.

📖 Read the full interview here: kurzlinks.de/ndwd
Sharepic showing a portrait picture of Claudine Kraft and her quote saying "Gender euqality is not just a women's issue – it affects us all. Real progress is made when we work together to find new solutions."
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kraftlabfr.bsky.social
Claudine Kraft's Lab @kraftlabfr.bsky.social · Feb 27
Just wrapped up the 2025 lab retreat! Great discussions, great company, and a fondue night in Basel to celebrate! 🫕✨
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