Louis-Marie Bobay
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lbobay.bsky.social
Louis-Marie Bobay
@lbobay.bsky.social
230 followers 230 following 10 posts
Associate Professor. NC State. Microbial Genomics, Evolution, Bioinformatics.
Posts Replies Media Videos
Reposted by Louis-Marie Bobay
kranzuschlab.bsky.social
Aude Bernheim @audeber.bsky.social and Eugene Koonin discuss one of most interesting questions in the field connecting bacterial and animal immunity!

www.nature.com/articles/s41...
The paradox of immune systems conservation between prokaryotes and eukaryotes - Nature Reviews Microbiology
The widespread prokaryotic immune systems, in particular restriction–modification, CRISPR–Cas and defensive toxin–antitoxin systems, are absent in eukaryotes, whereas relatively rare ones, such as Arg...
www.nature.com
February 6, 2026 at 3:15 PM
Reposted by Louis-Marie Bobay
gavin-conant.bsky.social
My book is available for pre-order!
www.routledge.com/Quantitative...

Or you can request an inspection copy here:
www.routledge.com/textbooks/ev...
January 29, 2026 at 1:09 PM
Reposted by Louis-Marie Bobay
dbikard.bsky.social
🚨 Hiring Alert! 🚨My lab at Institut Pasteur is recruiting several Postdocs! We have exciting open projects in: 🦠 Synthetic Biology and🛡️ Bacterial Immunity. Come do great science with us in the middle of Paris! 🇫🇷🥐 research.pasteur.fr/en/job/postd...
Postdoctoral position - Synthetic Biology / Bacterial Immunity - Research
The Bikard lab at Institut Pasteur in Paris is seeking to hire postdoctoral researchers. We are investigating bacteria / bacteriophages interactions, and the genetic innovation that happens at this in...
research.pasteur.fr
January 28, 2026 at 11:19 AM
lbobay.bsky.social
Congrats to @carolinamicro.bsky.social for leading this study! We looked at genome rearrangements over short evolutionary timescales. Among other things, we found that genomes are highly syntenic within most species. However, several bacteria experienced sudden and massive genome rearrangements.
January 27, 2026 at 3:09 PM
Reposted by Louis-Marie Bobay
cibiocm.bsky.social
🥁 NEW

Our study on infant gut microbiome and #straintransmission is now published in @nature.com:

doi.org/10.1038/s415...

1/10
Baby-to-baby strain transmission shapes the developing gut microbiome - Nature
A metagenomic survey of babies attending the first year of nursery detected extensive baby-to-baby microbial strain transmission, pointing to social interactions in infancy as crucial drivers of infan...
doi.org
January 21, 2026 at 6:24 PM
Reposted by Louis-Marie Bobay
symboevo.bsky.social
I’m excited to share a new paper by a super talented graduate-student-now-postdoc. Grateful to work with old and new collaborators!

Characterizing a novel Symbiopectobacterium MEX strain at the early stages of establishing a symbiotic relationship url: academic.oup.com/gbe/article/...
Characterizing a novel Symbiopectobacterium purcellii MEX strain at the early stages of establishing a symbiotic relationship
Abstract. Insects ally with microbial symbionts for a diversity of services. The range of these interactions is wide, spanning from beneficial to pathogeni
academic.oup.com
January 9, 2026 at 9:36 PM
Reposted by Louis-Marie Bobay
dbikard.bsky.social
Deadline is approaching (Feb 9) to apply for a PI position at Institut Pasteur. Come join us and contribute to an amazing scientific environment!!!
January 19, 2026 at 4:55 PM
Reposted by Louis-Marie Bobay
amazeld.bsky.social
a quick reminder!
January 18, 2026 at 1:26 PM
Reposted by Louis-Marie Bobay
labxc.bsky.social
Une opportunité unique de former des étudiants talentueux à la biologie des bactéries à l'ENS Lyon et mener des recherches sur les phages, l'immunité bactérienne, le transfert génétique horizontal (HGT) et/ou les éléments génétiques mobiles au sein du département de bactériologie du CIRI.
cinflammasome.bsky.social Thomas Henry @cinflammasome.bsky.social · 26d
📢 Recruitment of an Associate Professor (Maître de conférences) in Bacteriology at CIRI and ENS de Lyon.
Research at @ciri-lyon.bsky.social @francoisrousset.bsky.social
@labxc.bsky.social
Anti-phage Immunity, Horizontal gene/ MGE transfer
📚 Teaching at ENS de Lyon within the Department of Biology.
January 13, 2026 at 2:01 PM
Reposted by Louis-Marie Bobay
oborkowski.bsky.social
Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change
doi.org/10.64898/202...
January 8, 2026 at 7:36 AM
Reposted by Louis-Marie Bobay
epcrocha.bsky.social
The distinction between virulent & temperate phages gets fuzzier if one can find so many virulent phages in the sequences of bacterial genomes coming from standard lab "pure" cultures. Check Peter's thread on our work and the N&V by Carson & Hynes: doi.org/10.1038/s415...
#phagesky #microsky
January 5, 2026 at 4:41 PM
Reposted by Louis-Marie Bobay
nanditagarud.bsky.social
If you are interested in this work and are looking for a postdoc position, please get in touch -- we are actively looking for someone to join our group at UCLA!
December 17, 2025 at 6:53 PM
Reposted by Louis-Marie Bobay
labwaggoner.bsky.social
Recombination between strains fuels pervasive adaptive evolution among human gut commensal bacteria, and strongly implicate host diet and lifestyle as critical selection pressures @nature.com @nanditagarud.bsky.social
www.nature.com/articles/s41...
December 17, 2025 at 5:31 PM
Reposted by Louis-Marie Bobay
lebetimonas.bsky.social
Looking for a postdoc in 2026? The Ewel fellowship at UF provides $70K salary and $20K research support for 2 yrs. I'm happy to sponsor a postdoc interested in microbial ecology of Florida coastal ecosystems (seagrass, coral, mangroves, springs). 🦠 Due 1/11/26

postdoc.aa.ufl.edu/current-post...
postdoc.aa.ufl.edu
December 13, 2025 at 12:16 PM
Reposted by Louis-Marie Bobay
manuelkleiner.bsky.social
We are recruiting a Lab Manager/Research Specialist
jobs.ncsu.edu/postings/225...
Please re-post, thank you
Research and Lab Specialist
The Kleiner Lab at North Carolina State University (www.kleinerlab.org) is seeking a Research Specialist to support ongoing research on complex microbial communities, microbial symbioses, and metaprot...
jobs.ncsu.edu
December 12, 2025 at 7:12 PM
Reposted by Louis-Marie Bobay
drhhnz.bsky.social
It’s officially happening folks! The Microbial Population Biology Gordon Research Conference is back in Andover, New Hampshire starting June 27th of 2027!
See you there!!

@wcratcliff.bsky.social @ksbakes.bsky.social @surtlab.bsky.social

#microsky #mevosky
Screenshot from GRC portal confirming microbial population biology meeting June 27, 2027 in Andover, New Hampshire.
December 10, 2025 at 2:35 PM
Reposted by Louis-Marie Bobay
susanjohnston.bsky.social
Are you a recombination researcher heading to #SMBE2026? Submit your abstract to our Symposium, organised by Marie Raynaud, Laurent Duret, and myself. We're excited to have Aurora Ruiz-Herrera from UAB Barcelona as our invited speaker.
🧬🦄🦠🌿🐝🐟🍄🪱
@aruizherrera.bsky.social @duret-lbbe.bsky.social
official-smbe.bsky.social Society for Molecular Biology and Evolution @official-smbe.bsky.social · Dec 9
SMBE2026 Symposium 11 | The evolution of recombination landscapes

📨 Abstract submission
smbe2026.org/abstracts

📋 Programme details
smbe2026.org/programme

#SMBE2026
SMBE2026 Symposium 11 | The evolution of recombination landscapes
December 9, 2025 at 2:54 PM
Reposted by Louis-Marie Bobay
pasteur.fr
🔬 Call to create junior research groups at the Institut Pasteur

Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies

📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD

Apply now 📝 research.pasteur.fr/en/call/crea...

#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
Reposted by Louis-Marie Bobay
sylvainbrisse.bsky.social
Opening of a Group Leader position in AI in genomics at Institut Pasteur @pasteur.fr , Paris research.pasteur.fr/en/call/mid-...
Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research
Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...
research.pasteur.fr
December 6, 2025 at 9:49 AM
Reposted by Louis-Marie Bobay
fonamental.bsky.social
Natural and artificial variations of the standard genetic code www.cell.com/current-biol...
December 2, 2025 at 8:01 AM
Reposted by Louis-Marie Bobay
plosbiology.org
How do root #microbes respond to drought? This study finds that #Streptomyces responses are strain-specific & functionally diverse, with traits & #plant effects varying independently of phylogeny, stressing the need to resolve functional traits at the strain level @plosbiology.org 🧪 plos.io/4owtjIT
Pangenomic visualization of the genomic organization of all 12 Streptomyces isolates representing each of the four AC groups. Hierarchical clustering is based on orthogroup presence/absence using Euclidean distance and Ward’s linkage method. Colored rings show orthogroup presence/absence per isolate, the outer ring shows the number of contributing genomes, and the second outer ring shows the number of genes present in each orthogroup. The metadata table shows 1) experimental phenotype data (orange) of total siderophore production (SP, halo size on CAS-LB media), growth under osmotic stress (OST, 1.0M sorbitol), and the relative production of four individual siderophores in response to media supplemented with drought- vs. well-watered root tissue (EF1 and EF2, ferrioxamine EF; H, O-methyl desferrioxamine H, D4, derrioxamine D4), and 2) genome analysis data (dark blue), showing the number of gene copies that match with specific COG function search terms related to iron acquisition (iron and Sid, siderophores), carbon resource utilization (G-3-P, glycerol-3-phosphate), and osmotic stress response (ProP, FabG, OmpR, Kdp, Trk). Scale values represent Z-scores, where darker blue indicates more gene copies, and darker orange indicates more siderophore production, more growth under osmotic stress, or a larger halo.
December 1, 2025 at 9:20 AM
Reposted by Louis-Marie Bobay
ironark.bsky.social
metaTraits: a large-scale integration of microbial phenotypic trait information

academic.oup.com/nar/advance-...
metaTraits: a large-scale integration of microbial phenotypic trait information
Abstract. Microbes differ greatly in their organismal structure, physiology, and environmental adaptation, yet information about these phenotypic traits is
academic.oup.com
November 30, 2025 at 4:47 AM
Reposted by Louis-Marie Bobay
monicamedhist.bsky.social
Another addition to the 2nd Plague Pandemic bibliography. Why, when this relates to the 3rd Pandemic, instead of the 2nd? B/c the science about plague we've acquired from the unfortunate experience of Madagascar informs everything we can do in #medhist. www.nature.com/articles/s42...
Evaluating the early diversification of Yersinia pestis and its phylogeographic expansion over 96 years of evolution in Madagascar - Communications Biology
A comprehensive phylogenetic analysis of Yersinia pestis, the causative agent of plague, provides insight into the diversity and evolution of this pathogen in Madagascar. This study provides valuable ...
www.nature.com
November 29, 2025 at 9:13 PM
Reposted by Louis-Marie Bobay
audeber.bsky.social
🧬🛡️How are new immune mechanisms created?

We show how Lamassu antiphage system, originated from a DNA-repair complex and evolved into a compact and modular immune machine, wt Dinshaw Patel lab in @pnas.org.
👏 @matthieu-haudiquet.bsky.social, Arpita Chakravarti & all authors!

doi.org/10.1073/pnas...
November 27, 2025 at 9:35 AM
Reposted by Louis-Marie Bobay
linsalrob.bsky.social
Long read Metagenomics, #phage and #prophage in the gut by Ami Bhatt's group. Beautiful data showing changes in phages over two years

#phagesky

www.nature.com/articles/s41...
Long-read metagenomics reveals phage dynamics in the human gut microbiome - Nature
Complex prophage integration dynamics, including low-level induction, cross-family host range and transposase-mediated mobilization, challenge existing paradigms and deepen our understanding of phage–...
www.nature.com
November 26, 2025 at 9:55 PM