Shane Liddelow
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liddelowsa.bsky.social
Shane Liddelow
@liddelowsa.bsky.social
Neuroscientist and glial aficionado at NYU Grossman School of Medicine/NYU Langone Health in NYC. Posts in my individual/personal capacity.
My lab is full of awesome people doing amazing stuff - check them out: www.liddelowlab.com
he/him
#SfN #SocietyForGlia #Astrocytes

ENDING STRONG in Astrocyte land here in San Diego.
Thanks for being an amazing community, and apologies (one last time) for anyone I missed! Please comment below with extra awesome astrocyte sessions.

See you in 2026!
November 19, 2025 at 5:39 PM
#SfN25 #SocietyForGlia #Astrocytes

penultimate astrocyte sessions for 2025 - let's do this!
November 19, 2025 at 1:42 PM
www.biorxiv.org
November 18, 2025 at 8:58 PM
#SfN #SocietyForGlia
STARTING NOW!

Ending strong with the last www.liddelowlab.com presentations of the week.

@pryprk.bsky.social
talking about a world first mouse model for XDP... and OLIGODENDROCYTES!

@melcooperphd.bsky.social
presenting on astrocyte networks in the mouse forebrain.
November 18, 2025 at 8:58 PM
November 18, 2025 at 8:51 PM
#SfN25 #SocietyForGlia #Astrocytes

IT'S A BIG DAY - if you're unsure what do do this afternoon - it seems just going to poster row C is the best way to spend some time!

as always, apologies to those I have missed - please comment below with more sessions and presentations!
November 18, 2025 at 4:02 PM
IT'S A BUSY AFTERNOON FOR THE LAB!

@mrodea.bsky.social - astrocyte chromatin in reactive astrocytes across the forebrain

Nick Kathman - COCKROACH BRAIN ALERT! (is this the largest single cell atlas of an insect brain?)

@liddelowsa.bsky.social - multiomic approaches to study astrocyte reacitivity
November 17, 2025 at 8:39 PM
Reposted by Shane Liddelow
It's a packed day for our researchers at #SfN25. Come say hi!
November 17, 2025 at 4:52 PM
Astrocytes and oxytoxin - we got you! NOW!

#SfN25 #SocietyForGlia #Astrocytes
November 17, 2025 at 4:11 PM
Argh! Sorry! THANKS!
There's so many today (and we all know the app is horrible 🫠)
November 17, 2025 at 3:11 PM
#SfN25 #SocietyForGlia #Astrocytes

Monday is a BUSY day - see you all out there!
(apologies for anyone's presentation I missed - please comment below with details)
November 17, 2025 at 2:44 PM
#SocietyForGlia #SfN25 #Astrocytes

Sunday is a rest day for astrocytes it seems - but still lots of cool stuff to go and see.
Apologies again for anyone I missed - please link your presentations below
November 16, 2025 at 3:32 PM
#SocietyForGlia #SfN25 #Astrocytes

Astrocyte presentation round up for Day 1.
Sorry if I missed anyone, please comment below with others!

See you about the conference
November 15, 2025 at 8:35 PM
#SfN25 #SocietyForGlia #Astrocytes

@borderbiologist.bsky.social presenting now!
Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!
November 15, 2025 at 8:33 PM
Reposted by Shane Liddelow
Very happy to have contributed to this new review on Lewy body dementia in @thelancetneuro.bsky.social led by Sonja W. Scholz. We highlight the latest advances in genetics and pathology. @liddelowsa.bsky.social Check it out! www.sciencedirect.com/science/arti...
Advances in the genetics and pathology of Lewy body dementia
Lewy body dementia is a heterogeneous disease that is underdiagnosed and poorly understood. Pathologically, Lewy body dementia is characterised by the…
www.sciencedirect.com
November 13, 2025 at 12:56 AM
Reposted by Shane Liddelow
In case you were wondering what to do with precisely 150 minutes of your existence @sfn.org #SfN25 #SanDiego. Join our mini-symposium Single-Cell Multiomics in CNS Injury and Recovery. Guaranteed to contain many glial cells and at least a neuron. I am Co-chairing with Naomi Habib
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.

(1/2)
November 11, 2025 at 5:14 PM
(bonus)
thanks to the amazing @droligo.bsky.social and @amygleichman.bsky.social the social aspects of glial biology will be strongly represented.
(thanks also to @plasmidsaurus.bsky.social & Avantor for supporting our community!)
November 10, 2025 at 4:43 PM
November 10, 2025 at 4:43 PM
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.

(1/2)
November 10, 2025 at 4:43 PM
Reposted by Shane Liddelow
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal!

Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.

All welcome, please free to spread the word!
October 29, 2025 at 2:57 PM
Reposted by Shane Liddelow
Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com

www.nature.com/articles/s41...
Spatial dynamics of brain development and neuroinflammation - Nature
A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.
www.nature.com
November 5, 2025 at 4:03 PM
Reposted by Shane Liddelow
Oligodendrocytes support functional development of subcortical premotor neurons and navigation https://www.biorxiv.org/content/10.1101/2025.11.01.686017v1
November 2, 2025 at 10:15 AM
We've been doing some amazing stuff outside the astrocyte realm.
Check out our latest Oligo investigation led by @pryprk.bsky.social !
I am proud to share our work on X-linked Dystonia-Parkinsonism β€” a rare neurodegenerative movement disorder driven by a SINE-VNTR-Alu retrotransposon insertion in the TAF1 gene.

Read our two companion papers:
πŸ”Ή www.biorxiv.org/content/10.1...
πŸ”Ή www.biorxiv.org/content/10.1...

🧡 Highlights below!
October 24, 2025 at 4:40 PM
Reposted by Shane Liddelow
Astrocyte networks are much larger than previously thought, which β€œflips the way we think about astrocytes and what their networks may mean,” says @liddelowsa.bsky.social.

By @callimcflurry.bsky.social

#neuroskyence

www.thetransmitter.org/astrocytes/a...
September 4, 2025 at 8:50 PM
thanks for the great insights!
September 3, 2025 at 1:51 PM