Uncertainty Principle
@luckypetie.medsky.social
Medicine, Covid science, politics, literature, science, emotions, neuroscience, philosophy, humor, Mama, infinitely curious, still working on my magical thinking m, DEMOCRACY
Pinned
Putting a price on healthcare, puts a price on health and things like expected years of life and other quantifiable life factors until each life has a value. This is fundamentally immoral.
Reposted by Uncertainty Principle
I am shocked that this study of fatigue in Long Covid patients utilizing deception in the research design was IRB approved. Deception is profoundly disrespectful & unethical in this context and shows a lack of judgment, lack of creativity in addressing research issues, and shallow understanding.
Well done & thanks to these healthcare professionals (PTs)/similar ( @sunsopeningband.bsky.social @profmarkfaghy.bsky.social et al) for this new e-letter 👏
"In the Long Run, Misleading Participants Will Harm More Than Help in Long COVID Research"
bmjopen.bmj.com/content/15/1...
#LongCOVID #PEM
"In the Long Run, Misleading Participants Will Harm More Than Help in Long COVID Research"
bmjopen.bmj.com/content/15/1...
#LongCOVID #PEM
![Published on: 9 December 2025
In the Long Run, Misleading Participants Will Harm More Than Help in Long COVID Research
Todd E. Davenport, Professor & Chair University of the Pacific, Workwell Foundation
Other Contributors:
Staci R. Stevens, Exercise Physiologist
Mark A. Faghy, Professor
Jessica DeMars, Respiratory Physiotherapist
J. Mark Van Ness, Professor & Chair
Respect for persons, beneficence, and justice are bedrock ethical principles in science. They are especially important when studying vulnerable populations. Billias et al. argue that deception is necessary to assure the internal validity of their exercise study involving people living with long COVID.[1] Here, we assert the use of deception is ethically indefensible and scientifically unnecessary in this population. It undermines informed consent, increases risks for harms, exploits the vulnerability of participants, and erodes trust in science and health care, all while exploring a question that already has been asked and answered satisfactorily enough to inform clinical recommendations.
Physical activity is a common trigger for post-exertional malaise (PEM),[2 3] which is common in people living with long COVID.[4] PEM involves an impaired recovery response from exertion that is distinct from deconditioning.[5 6] The hallmark of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is PEM. Exercise is no longer recommended in contemporary clinical guidance for ME/CFS, because an accumulation of evidence from research and lived experience suggests it is likely to cause avoidable harms.[7] Exercise prescription without adequate safeguards for PEM even may be considered negligent practice. The protocol acknowledges people living with PEM often worsen with exercise dosages that may be appropriate for other conditions.[1] Several of the authors of this protocol also previously published a systematic review acknowledging risks of exercise in people with long COVID related to PEM.[8] However, the author…](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:43rudsv62fuwsmnk7oppgtdy/bafkreidl77x7uweergov5gcuvlzqo7ehnvalbag3u44hniwvoh5uuc2ccy@jpeg)
December 10, 2025 at 12:32 AM
I am shocked that this study of fatigue in Long Covid patients utilizing deception in the research design was IRB approved. Deception is profoundly disrespectful & unethical in this context and shows a lack of judgment, lack of creativity in addressing research issues, and shallow understanding.
Reposted by Uncertainty Principle
Way to go, #Missouri! 🎉 www.theguardian.com/us-news/2025...
Organizers submit enough signatures to block gerrymandered Missouri map
More than 300,000 signatures delivered to secretary of state to force referendum on Republican-drawn map
www.theguardian.com
December 10, 2025 at 12:55 AM
Way to go, #Missouri! 🎉 www.theguardian.com/us-news/2025...
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Moscow says that the United States under the MAGA regime are in alignment with their vision regarding security strategy.
It was revealed that Putin’s Russia plotted last year to plant bombs on US-bound flights to disrupt the airline industry.
There are terrorists in the WH.
It was revealed that Putin’s Russia plotted last year to plant bombs on US-bound flights to disrupt the airline industry.
There are terrorists in the WH.
December 9, 2025 at 11:55 PM
Moscow says that the United States under the MAGA regime are in alignment with their vision regarding security strategy.
It was revealed that Putin’s Russia plotted last year to plant bombs on US-bound flights to disrupt the airline industry.
There are terrorists in the WH.
It was revealed that Putin’s Russia plotted last year to plant bombs on US-bound flights to disrupt the airline industry.
There are terrorists in the WH.
Reposted by Uncertainty Principle
A president whose decisions left deaths, trauma, and democratic wreckage behind once said he might never “make heaven.” For one fleeting moment, he finally told the truth.
theintellectualistofficial.substack.com/p/trump-said...
theintellectualistofficial.substack.com/p/trump-said...
December 10, 2025 at 1:00 AM
A president whose decisions left deaths, trauma, and democratic wreckage behind once said he might never “make heaven.” For one fleeting moment, he finally told the truth.
theintellectualistofficial.substack.com/p/trump-said...
theintellectualistofficial.substack.com/p/trump-said...
Reposted by Uncertainty Principle
Oh that's not--
December 10, 2025 at 12:49 AM
Oh that's not--
Reposted by Uncertainty Principle
Mackenzie Scott Announces $7 Billion of Giving This Year www.nytimes.com/2025/12/09/b...
MacKenzie Scott Announces $7 Billion of Charitable Giving This Year
www.nytimes.com
December 10, 2025 at 1:03 AM
Mackenzie Scott Announces $7 Billion of Giving This Year www.nytimes.com/2025/12/09/b...
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A brief obituary for my father is here. The support from my online community here has been such a comfort in the last couple of difficult days.
www.dignitymemorial.com/obituaries/h...
www.dignitymemorial.com/obituaries/h...
December 10, 2025 at 1:03 AM
A brief obituary for my father is here. The support from my online community here has been such a comfort in the last couple of difficult days.
www.dignitymemorial.com/obituaries/h...
www.dignitymemorial.com/obituaries/h...
Reposted by Uncertainty Principle
Democrats—if they take back the House—already needed to launch an investigation into Bove’s egregious criminal conduct on Trump’s behalf before his confirmation to the 3rd Circuit. But they should also look into his brazen partisanship, which obviously violates the judicial Code of Conduct.
Via MS NOW: Emil Bove is in attendance at Trump’s speech in Pennsylvania tonight.
December 10, 2025 at 1:00 AM
Democrats—if they take back the House—already needed to launch an investigation into Bove’s egregious criminal conduct on Trump’s behalf before his confirmation to the 3rd Circuit. But they should also look into his brazen partisanship, which obviously violates the judicial Code of Conduct.
Reposted by Uncertainty Principle
Susan Tincher, a 55-year-old American citizen, said agents told her in the truck that if she didn’t watch herself “they were going to pull me over to the side of the road and give me this OC,” law enforcement shorthand for pepper spray.
Federal agents arrest citizen observer watching ICE detain neighbors on her north Minneapolis block
Susan Tincher, a 55-year-old American citizen, appears to be the first observer arrested by federal immigration enforcement officers since the agency launched an immigration surge in the Twin Cities l...
www.mprnews.org
December 9, 2025 at 11:19 PM
Susan Tincher, a 55-year-old American citizen, said agents told her in the truck that if she didn’t watch herself “they were going to pull me over to the side of the road and give me this OC,” law enforcement shorthand for pepper spray.
Reposted by Uncertainty Principle
It wasn’t a close victory. The Democrat whooped the Republican’s hiney by 20 points.
Next November will be a GOP bloodbath.
Next November will be a GOP bloodbath.
Eileen Higgins just became the first Democrat elected mayor of Miami in nearly 30 years.
December 10, 2025 at 12:52 AM
It wasn’t a close victory. The Democrat whooped the Republican’s hiney by 20 points.
Next November will be a GOP bloodbath.
Next November will be a GOP bloodbath.
Reposted by Uncertainty Principle
via AIJAC - Australia/Israel & Jewish Affairs Council
Archaeologists have uncovered a massive, remarkably intact section of Jerusalem’s ancient Maccabean-period city wall – more than 40 metres long and five metres high – at the Tower of David.
1/5
Archaeologists have uncovered a massive, remarkably intact section of Jerusalem’s ancient Maccabean-period city wall – more than 40 metres long and five metres high – at the Tower of David.
1/5
December 10, 2025 at 1:04 AM
via AIJAC - Australia/Israel & Jewish Affairs Council
Archaeologists have uncovered a massive, remarkably intact section of Jerusalem’s ancient Maccabean-period city wall – more than 40 metres long and five metres high – at the Tower of David.
1/5
Archaeologists have uncovered a massive, remarkably intact section of Jerusalem’s ancient Maccabean-period city wall – more than 40 metres long and five metres high – at the Tower of David.
1/5
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Earlier today, Elias Law Group Chair @marcelias.bsky.social argued a major campaign finance case before the U.S. Supreme Court on behalf of the DNC, DSCC, and DCCC.
Learn more about what's at stake in this critical case:
elias.law/newsroom/pre...
Learn more about what's at stake in this critical case:
elias.law/newsroom/pre...
Marc Elias Argues Major Campaign Finance Case Before the U.S. Supreme Court
elias.law
December 9, 2025 at 8:55 PM
Earlier today, Elias Law Group Chair @marcelias.bsky.social argued a major campaign finance case before the U.S. Supreme Court on behalf of the DNC, DSCC, and DCCC.
Learn more about what's at stake in this critical case:
elias.law/newsroom/pre...
Learn more about what's at stake in this critical case:
elias.law/newsroom/pre...
Reposted by Uncertainty Principle
The destruction of the enterprise of US academic science has been one of the most confounding aspects of a hugely confounding year. My @statnews.com colleagues are writing about the consequences for individuals & the country.
You want to read this series.
www.statnews.com/american-sci...
You want to read this series.
www.statnews.com/american-sci...
American Science, Shattered
An eight-decade partnership between universities and the federal government made U.S. science preeminent. It took Trump less than a year to shred that
www.statnews.com
December 9, 2025 at 5:23 PM
The destruction of the enterprise of US academic science has been one of the most confounding aspects of a hugely confounding year. My @statnews.com colleagues are writing about the consequences for individuals & the country.
You want to read this series.
www.statnews.com/american-sci...
You want to read this series.
www.statnews.com/american-sci...
Reposted by Uncertainty Principle
Russia reportedly plotted last year to plant bombs on US-bound flights.
Make no mistake if Trump says something that Putin doesnt agree, there will be mass hybrid war in USA.
Make no mistake if Trump says something that Putin doesnt agree, there will be mass hybrid war in USA.
December 9, 2025 at 8:01 PM
Russia reportedly plotted last year to plant bombs on US-bound flights.
Make no mistake if Trump says something that Putin doesnt agree, there will be mass hybrid war in USA.
Make no mistake if Trump says something that Putin doesnt agree, there will be mass hybrid war in USA.
Reposted by Uncertainty Principle
Most people know the Holocaust happened throughout Nazi-occupied Europe, but did you know the Holocaust heavily impacted Tunisia as well?
It's a lesser-known but incredibly important part of World War II history, where Tunisia's ancient Jewish community faced terrible persecution.
🧵
1/7
It's a lesser-known but incredibly important part of World War II history, where Tunisia's ancient Jewish community faced terrible persecution.
🧵
1/7
December 9, 2025 at 5:56 PM
Most people know the Holocaust happened throughout Nazi-occupied Europe, but did you know the Holocaust heavily impacted Tunisia as well?
It's a lesser-known but incredibly important part of World War II history, where Tunisia's ancient Jewish community faced terrible persecution.
🧵
1/7
It's a lesser-known but incredibly important part of World War II history, where Tunisia's ancient Jewish community faced terrible persecution.
🧵
1/7
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New research found that Instacart is charging shoppers different prices — despite ordering the same items from the same store at the same time.
The price differences could amount to an extra $1,200 a year for the average household of four.
Corporate greed is out of control.
The price differences could amount to an extra $1,200 a year for the average household of four.
Corporate greed is out of control.
Instacart’s AI-Enabled Pricing Experiments May Be Inflating Your Grocery Bill, CR and Groundwork Collaborative Investigation Finds - Consumer Reports
Exclusive: Instacart’s AI pricing may be inflating your grocery bill.
www.consumerreports.org
December 9, 2025 at 7:15 PM
New research found that Instacart is charging shoppers different prices — despite ordering the same items from the same store at the same time.
The price differences could amount to an extra $1,200 a year for the average household of four.
Corporate greed is out of control.
The price differences could amount to an extra $1,200 a year for the average household of four.
Corporate greed is out of control.
Reposted by Uncertainty Principle
This is a perfect explanation of why 'AI' that exists is nothing like and can never be anything like the 'AI' of science fiction that the grifters want us to believe this 'AI' is.
December 9, 2025 at 3:00 PM
This is a perfect explanation of why 'AI' that exists is nothing like and can never be anything like the 'AI' of science fiction that the grifters want us to believe this 'AI' is.
Reposted by Uncertainty Principle
"AI is the asbestos in the walls of our technological society, stuffed there with wild abandon by a finance sector and tech monopolists run amok. We will be excavating it for a generation or more."
This piece on AI by Cory Doctorow is spectactular.
pluralistic.net/2025/12/05/p...
This piece on AI by Cory Doctorow is spectactular.
pluralistic.net/2025/12/05/p...
December 9, 2025 at 2:58 PM
"AI is the asbestos in the walls of our technological society, stuffed there with wild abandon by a finance sector and tech monopolists run amok. We will be excavating it for a generation or more."
This piece on AI by Cory Doctorow is spectactular.
pluralistic.net/2025/12/05/p...
This piece on AI by Cory Doctorow is spectactular.
pluralistic.net/2025/12/05/p...
Reposted by Uncertainty Principle
Russia’s assets in the West are not hiding their traitorous plans
December 9, 2025 at 1:35 PM
Russia’s assets in the West are not hiding their traitorous plans
Reposted by Uncertainty Principle
And even if you're right, the punishment for drug smuggling isn't death.
Rand Paul: "This is an insane policy. It's inconsistent. It's not war. It's not the way we've ever done this. If we can blow up a boat in the ocean, what about when they get to Miami & put it in a truck? Can you shoot a grenade launcher at the truck? No! We arrest people b/c sometimes we're wrong."
December 9, 2025 at 6:14 PM
And even if you're right, the punishment for drug smuggling isn't death.
Reposted by Uncertainty Principle
Breaking News: Gov. JB Pritzker of Illinois signed a bill that restricts immigration enforcement near state courthouses and makes it easier to sue ICE agents.
December 9, 2025 at 4:52 PM
Breaking News: Gov. JB Pritzker of Illinois signed a bill that restricts immigration enforcement near state courthouses and makes it easier to sue ICE agents.
Reposted by Uncertainty Principle
Political reforms which would set us on a path towards a new system which don’t require a constitutional amendment:
- Proportional representation in the House with RCV in the Senate
- Expanding the Supreme Court and limiting its power
- Abolishing the filibuster
- Adding DC and PR as states
- Proportional representation in the House with RCV in the Senate
- Expanding the Supreme Court and limiting its power
- Abolishing the filibuster
- Adding DC and PR as states
December 9, 2025 at 2:42 AM
Political reforms which would set us on a path towards a new system which don’t require a constitutional amendment:
- Proportional representation in the House with RCV in the Senate
- Expanding the Supreme Court and limiting its power
- Abolishing the filibuster
- Adding DC and PR as states
- Proportional representation in the House with RCV in the Senate
- Expanding the Supreme Court and limiting its power
- Abolishing the filibuster
- Adding DC and PR as states
Reposted by Uncertainty Principle
In Kansas City, 816 COVID Crew is working to build solidarity during an ongoing pandemic by distributing N95, KN95, KF94, and CAN99 masks to the public. It’s fantastic to see the coverage by Noah Taborda @kcur.org bit.ly/KCUR_FREEMASK
Annotation: www.facebook.com/masktogether...
Annotation: www.facebook.com/masktogether...
December 9, 2025 at 3:26 PM
In Kansas City, 816 COVID Crew is working to build solidarity during an ongoing pandemic by distributing N95, KN95, KF94, and CAN99 masks to the public. It’s fantastic to see the coverage by Noah Taborda @kcur.org bit.ly/KCUR_FREEMASK
Annotation: www.facebook.com/masktogether...
Annotation: www.facebook.com/masktogether...
Reposted by Uncertainty Principle
"Nothing is better settled at the common law than the doctrine that the children even of aliens born in a country while the parents are resident there under the protection of the government and owing a temporary allegiance thereto are subjects by birth."
Inglis v. Sailor's Snug Harbor (U.S. 1830).
Inglis v. Sailor's Snug Harbor (U.S. 1830).
December 9, 2025 at 6:24 PM
"Nothing is better settled at the common law than the doctrine that the children even of aliens born in a country while the parents are resident there under the protection of the government and owing a temporary allegiance thereto are subjects by birth."
Inglis v. Sailor's Snug Harbor (U.S. 1830).
Inglis v. Sailor's Snug Harbor (U.S. 1830).
Reposted by Uncertainty Principle
"Amazing Grace" Hopper was born #OTD in 1906.
+PhD in #Mathematics, Yale
+Rear Admiral, US Navy
+Invented the first computer compiler, foundational to modern software
+Co-developed COBOL, one of the earliest standardized computer languages
#WomenInSTEM #legend
+PhD in #Mathematics, Yale
+Rear Admiral, US Navy
+Invented the first computer compiler, foundational to modern software
+Co-developed COBOL, one of the earliest standardized computer languages
#WomenInSTEM #legend
December 9, 2025 at 6:32 PM
"Amazing Grace" Hopper was born #OTD in 1906.
+PhD in #Mathematics, Yale
+Rear Admiral, US Navy
+Invented the first computer compiler, foundational to modern software
+Co-developed COBOL, one of the earliest standardized computer languages
#WomenInSTEM #legend
+PhD in #Mathematics, Yale
+Rear Admiral, US Navy
+Invented the first computer compiler, foundational to modern software
+Co-developed COBOL, one of the earliest standardized computer languages
#WomenInSTEM #legend