Marcela Uliano-Silva
@marcelauliano.bsky.social
Genome Scientist | Tree of Life Wellcome Sanger
Reposted by Marcela Uliano-Silva
final week to apply for @sangerinstitute.bsky.social PhD programme (due Nov 27th) -- free to apply, open to anyone anywhere, and a superb training opportunity for students interested in genomic approaches applied to biodiversity, pathogens, vectors, and of course us pesky humans.
November 20, 2025 at 12:07 PM
final week to apply for @sangerinstitute.bsky.social PhD programme (due Nov 27th) -- free to apply, open to anyone anywhere, and a superb training opportunity for students interested in genomic approaches applied to biodiversity, pathogens, vectors, and of course us pesky humans.
Reposted by Marcela Uliano-Silva
We’ve just started our 5-day course with @marcelauliano.bsky.social & Joao on assembling eukaryotic genomes with @pacbio.bsky.social long reads and Hi-C! Attendees are learning how to handle raw data, run assemblies, scaffold chromosomes & assess quality.
November 11, 2025 at 1:11 PM
We’ve just started our 5-day course with @marcelauliano.bsky.social & Joao on assembling eukaryotic genomes with @pacbio.bsky.social long reads and Hi-C! Attendees are learning how to handle raw data, run assemblies, scaffold chromosomes & assess quality.
Reposted by Marcela Uliano-Silva
Join our 5-day online course: “Eukaryotic Genome Assembly Using @pacbio.bsky.social and Hi-C” with @marcelauliano.bsky.social l & Joao and get hands-on experience with long-read sequencing and Hi-C scaffolding.
Last seats left: www.physalia-courses.org/courses-work...
Last seats left: www.physalia-courses.org/courses-work...
October 30, 2025 at 5:30 PM
Join our 5-day online course: “Eukaryotic Genome Assembly Using @pacbio.bsky.social and Hi-C” with @marcelauliano.bsky.social l & Joao and get hands-on experience with long-read sequencing and Hi-C scaffolding.
Last seats left: www.physalia-courses.org/courses-work...
Last seats left: www.physalia-courses.org/courses-work...
Reposted by Marcela Uliano-Silva
Amanda Gardiner follows at the #biodiversity25 with a presentation about #genetic_diversity in sharks, rays and other vertebrates. She analyzed ROH, homozygous regions in vertebrates genomes produced by the VGP. Critically endangered species have more frequently long ROH than other species.
October 29, 2025 at 10:15 AM
Amanda Gardiner follows at the #biodiversity25 with a presentation about #genetic_diversity in sharks, rays and other vertebrates. She analyzed ROH, homozygous regions in vertebrates genomes produced by the VGP. Critically endangered species have more frequently long ROH than other species.
Reposted by Marcela Uliano-Silva
Elisa Ramos brings us a presentation about #gulls at the #biodiversity25. The large white-headed gulls lineage has one of the faster #radiation processes of the birds of the northern hemisphere. LarOmics project aims to elucidate the genetic base of the gull #evolution.
October 28, 2025 at 2:56 PM
Elisa Ramos brings us a presentation about #gulls at the #biodiversity25. The large white-headed gulls lineage has one of the faster #radiation processes of the birds of the northern hemisphere. LarOmics project aims to elucidate the genetic base of the gull #evolution.
Reposted by Marcela Uliano-Silva
I am genuinely impressed by large language models - they can absorb disparate components of text into some consolidated view, they can produce extremely good language and - with the right model - translate pretty well between languages and they are an excellent text based UI for humans to use. But..
October 26, 2025 at 7:48 AM
I am genuinely impressed by large language models - they can absorb disparate components of text into some consolidated view, they can produce extremely good language and - with the right model - translate pretty well between languages and they are an excellent text based UI for humans to use. But..
Reposted by Marcela Uliano-Silva
Celebrating the first 1000 genomes of Lepidoptera in Europe, sequenced at @sangerinstitute.bsky.social in collaboration with sampling hubs across the UK via the DToL project www.darwintreeoflife.org & across Europe via
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
October 15, 2025 at 9:17 PM
Celebrating the first 1000 genomes of Lepidoptera in Europe, sequenced at @sangerinstitute.bsky.social in collaboration with sampling hubs across the UK via the DToL project www.darwintreeoflife.org & across Europe via
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
Reposted by Marcela Uliano-Silva
🏙️ Last week, #ERGA joined the @vertebrategenomes.bsky.social #VGP Conference in NYC, a great chance to connect with @ebpgenome.bsky.social projects and share progress on #FAIR genome assemblies & reporting under @biogeneurope.bsky.social
www.erga-biodiversity.eu/post/erga-me... #genomes #conference
www.erga-biodiversity.eu/post/erga-me... #genomes #conference
ERGA meets VGP in New York City
Last week, ERGA was present at the Vertebrate Genomes Project 2025 Conference, held at The Rockefeller University in New York City from September 30 and October 1. ERGA and VGP share a long-standing c...
www.erga-biodiversity.eu
October 9, 2025 at 10:06 AM
🏙️ Last week, #ERGA joined the @vertebrategenomes.bsky.social #VGP Conference in NYC, a great chance to connect with @ebpgenome.bsky.social projects and share progress on #FAIR genome assemblies & reporting under @biogeneurope.bsky.social
www.erga-biodiversity.eu/post/erga-me... #genomes #conference
www.erga-biodiversity.eu/post/erga-me... #genomes #conference
Reposted by Marcela Uliano-Silva
Early bird applications are now open! Go go go genomics!
Applications are now open for the Workshop on Genomics 2026 (11-24 Jan) in Cesky Krumlov, Czechia. For the first time, we are offering Early Bird Registration discounts! 🐣 Do not miss the chance! 🤩 Help us spread the word among friends and colleagues! 🙆🏽♀️ #evomics2026
evomics.org/apply-worksh...
evomics.org/apply-worksh...
July 1, 2025 at 9:38 AM
Early bird applications are now open! Go go go genomics!
Reposted by Marcela Uliano-Silva
Preprint Alert! 🦥
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
Retrocopy formation and domestication shape genome evolution in sloths and other xenarthrans
Xenarthrans, comprising sloths, anteaters, and armadillos, represent one of the most morphologically and physiologically specialised mammalian clades, yet the genomic basis of their adaptations remain...
www.biorxiv.org
October 2, 2025 at 9:16 PM
Preprint Alert! 🦥
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
Preprint Alert! 🦥
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
Retrocopy formation and domestication shape genome evolution in sloths and other xenarthrans
Xenarthrans, comprising sloths, anteaters, and armadillos, represent one of the most morphologically and physiologically specialised mammalian clades, yet the genomic basis of their adaptations remain...
www.biorxiv.org
October 2, 2025 at 9:16 PM
Preprint Alert! 🦥
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...
Reposted by Marcela Uliano-Silva
PhD opportunity in Bodø! You’ll sequence genomes from invasive and non-invasive slug (A. vulgaris) populations to uncover the molecular basis of invasion dynamics. Supervised by Prof. Les Noble & co-supervisor by me. Fully funded, cutting-edge science, great team. Apply by Sept 21: shorturl.at/zJT06
shorturl.at
September 8, 2025 at 9:12 AM
PhD opportunity in Bodø! You’ll sequence genomes from invasive and non-invasive slug (A. vulgaris) populations to uncover the molecular basis of invasion dynamics. Supervised by Prof. Les Noble & co-supervisor by me. Fully funded, cutting-edge science, great team. Apply by Sept 21: shorturl.at/zJT06
Fantastic and elegant! By the amazing @charlottewright.bsky.social et al!
How many chromosomes can an animal have?
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
Constraints on chromosome evolution revealed by the 229 chromosome pairs of the Atlas blue butterfly
The genome of the Atlas blue butterfly contains ten times more chromosomes than most
butterflies, and more than any other known diploid animal. Wright et al. show that
this extraordinary karyotype is ...
tinyurl.com
September 12, 2025 at 9:37 AM
Fantastic and elegant! By the amazing @charlottewright.bsky.social et al!
PhD opportunity in Bodø! You’ll sequence genomes from invasive and non-invasive slug (A. vulgaris) populations to uncover the molecular basis of invasion dynamics. Supervised by Prof. Les Noble & co-supervisor by me. Fully funded, cutting-edge science, great team. Apply by Sept 21: shorturl.at/zJT06
shorturl.at
September 8, 2025 at 9:12 AM
PhD opportunity in Bodø! You’ll sequence genomes from invasive and non-invasive slug (A. vulgaris) populations to uncover the molecular basis of invasion dynamics. Supervised by Prof. Les Noble & co-supervisor by me. Fully funded, cutting-edge science, great team. Apply by Sept 21: shorturl.at/zJT06
Reposted by Marcela Uliano-Silva
This was both fun and terrifying to tape! Awesome to talk with @glennislogsdon.bsky.social and @aphillippy.bsky.social about our sequencing data / paper, the improvements to large-scale sequencing projects, and what this means for our understanding of our DNA!
Complete genomes alert! @glennislogsdon.bsky.social, @christinebeck.bsky.social, and I were on @scifri.bsky.social today talking about "Complex genetic variation in nearly complete human genomes"
📄 www.nature.com/articles/s41...
📻 www.sciencefriday.com/segments/65-...
📄 www.nature.com/articles/s41...
📻 www.sciencefriday.com/segments/65-...
65 Genomes Expand Our Picture Of Human Genetics
Researchers closely examined the genomes of 65 individuals to paint a more complex, and more complete, picture of human genetic diversity.
www.sciencefriday.com
August 1, 2025 at 9:02 PM
This was both fun and terrifying to tape! Awesome to talk with @glennislogsdon.bsky.social and @aphillippy.bsky.social about our sequencing data / paper, the improvements to large-scale sequencing projects, and what this means for our understanding of our DNA!
Reposted by Marcela Uliano-Silva
This Labour government has failed. People want real transformative politics – we will give it to them | Jeremy Corbyn
This Labour government has failed. People want real transformative politics – we will give it to them | Jeremy Corbyn
More than 500,000 people have signed up to our new party to help build a genuine alternative to poverty, inequality and war, says former Labour leader Jeremy Corbyn
www.theguardian.com
July 29, 2025 at 5:59 PM
This Labour government has failed. People want real transformative politics – we will give it to them | Jeremy Corbyn
Reposted by Marcela Uliano-Silva
Struggling to find the tiny microchromosomes in draft bird genome assemblies?
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
May 16, 2025 at 10:07 AM
Struggling to find the tiny microchromosomes in draft bird genome assemblies?
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
Reposted by Marcela Uliano-Silva
Proud to have authored this review with brilliant people. Hope we inspire more attempts to sequence the #protist genomes that are within reach! Huge thanks to Alexandra Schoenle for leading. #ProtistsOnSky
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
June 13, 2025 at 8:48 AM
Proud to have authored this review with brilliant people. Hope we inspire more attempts to sequence the #protist genomes that are within reach! Huge thanks to Alexandra Schoenle for leading. #ProtistsOnSky
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
Now out! Paper led by @philmor1964.bsky.social and the The Cetacean Genomes Project. An effort by many, we present 13 new, high-quality reference genomes for cetaceans 🐬🐋 following @vertebrategenomes.bsky.social and @ebpgenome.bsky.social standards for a group that is very hard to sample from.
July 18, 2025 at 9:16 AM
Now out! Paper led by @philmor1964.bsky.social and the The Cetacean Genomes Project. An effort by many, we present 13 new, high-quality reference genomes for cetaceans 🐬🐋 following @vertebrategenomes.bsky.social and @ebpgenome.bsky.social standards for a group that is very hard to sample from.
Reposted by Marcela Uliano-Silva
This course with @marcelauliano.bsky.social and @ferreiranunesjoao.bsky.social will introduce the audience to a spectrum of methods which are present in a usual assembly workflow, starting from raw data and finishing with a fully assembled genome @pacbio.bsky.social
Check it out shorturl.at/UEmOH
Check it out shorturl.at/UEmOH
July 3, 2025 at 8:42 AM
This course with @marcelauliano.bsky.social and @ferreiranunesjoao.bsky.social will introduce the audience to a spectrum of methods which are present in a usual assembly workflow, starting from raw data and finishing with a fully assembled genome @pacbio.bsky.social
Check it out shorturl.at/UEmOH
Check it out shorturl.at/UEmOH
Reposted by Marcela Uliano-Silva
Our newest unofficial video series—deep-sea animals that dance better than you 💃
Most sea cucumbers live a sedentary life on the bottom of the ocean, but some take a break from eating and pooping on the seafloor to go for a quick swim. They may do it as a defensive behavior or to find a mate.
Most sea cucumbers live a sedentary life on the bottom of the ocean, but some take a break from eating and pooping on the seafloor to go for a quick swim. They may do it as a defensive behavior or to find a mate.
June 27, 2025 at 9:29 PM
Our newest unofficial video series—deep-sea animals that dance better than you 💃
Most sea cucumbers live a sedentary life on the bottom of the ocean, but some take a break from eating and pooping on the seafloor to go for a quick swim. They may do it as a defensive behavior or to find a mate.
Most sea cucumbers live a sedentary life on the bottom of the ocean, but some take a break from eating and pooping on the seafloor to go for a quick swim. They may do it as a defensive behavior or to find a mate.
Reposted by Marcela Uliano-Silva
Interested in Genome Assembly? Do you want to learn how to assemble the genome of your species using @pacbio.bsky.social and HI-C data? Join us in November for the 6th edition of this course with @marcelauliano.bsky.social & @ferreiranunesjoao.bsky.social
🔗 www.physalia-courses.org/courses-work...
🔗 www.physalia-courses.org/courses-work...
April 2, 2025 at 3:47 PM
Interested in Genome Assembly? Do you want to learn how to assemble the genome of your species using @pacbio.bsky.social and HI-C data? Join us in November for the 6th edition of this course with @marcelauliano.bsky.social & @ferreiranunesjoao.bsky.social
🔗 www.physalia-courses.org/courses-work...
🔗 www.physalia-courses.org/courses-work...
Reposted by Marcela Uliano-Silva
if you have an interest in improving the genomic resources available for mosquitoes, please fill in our google form at tinyurl.com/MosquitoReferenceGenomes. please share this with colleagues who might be interested. thank you! [3/3]
Register your interest in participating in the Global Culicidae Reference Genomes Project
We are seeking mosquito biologists around the world who would be interested in collecting and contributing specimens of any vector species that currently lacks a reference genome.
Aim: We are aiming ...
tinyurl.com
February 24, 2025 at 10:51 AM
if you have an interest in improving the genomic resources available for mosquitoes, please fill in our google form at tinyurl.com/MosquitoReferenceGenomes. please share this with colleagues who might be interested. thank you! [3/3]
Reposted by Marcela Uliano-Silva
please take this survey if you use Darwin Tree of Life genomes! we are really keen to understand impact of these genomes on your science and wider work. Thank you!
Do you use Darwin Tree of Life (DToL) genomes for your work or grant applications? If so, can you please fill out this form? docs.google.com/forms/d/e/1F... We are gathering info on how DToL genomes are used. It will help us raise money to continue producing publicly available high-quality genomes.
Darwin Tree of Life Impact Assessment
This form is used to share information within DToL about case studies, ongoing research, and funding awards that demonstrate the impact the Darwin Tree of Life consortium project has had on Global and...
docs.google.com
February 25, 2025 at 12:47 PM
please take this survey if you use Darwin Tree of Life genomes! we are really keen to understand impact of these genomes on your science and wider work. Thank you!
Reposted by Marcela Uliano-Silva
Last two weeks to register for the workshop on #k-mer s in biodiversity genomics 🧬💻! With @connectingscience.bsky.social @katiejenike.bsky.social @rayanchikhi.bsky.social and Gene Myers.
coursesandconferences.wellcomeconnectingscience.org/event/k-mer-...
coursesandconferences.wellcomeconnectingscience.org/event/k-mer-...
February 28, 2025 at 11:20 AM
Last two weeks to register for the workshop on #k-mer s in biodiversity genomics 🧬💻! With @connectingscience.bsky.social @katiejenike.bsky.social @rayanchikhi.bsky.social and Gene Myers.
coursesandconferences.wellcomeconnectingscience.org/event/k-mer-...
coursesandconferences.wellcomeconnectingscience.org/event/k-mer-...