Christine Beck
@christinebeck.bsky.social
Associate Professor of Genetics and Genome Sciences at UConn Health and The Jackson Laboratory
Transposons, Structural Variation, Genomics, Gardening, Loud Music, Mom
Transposons, Structural Variation, Genomics, Gardening, Loud Music, Mom
Reposted by Christine Beck
Ribosomal RNA (rRNA) genes are found in hundreds of copies in the human genome.
Do sequence variations in these paralogs change the ribosome function? Yes!
I am excited to share our new preprint @mbarnalab @jkpritch in collaboration with Calico:
www.medrxiv.org/content/10.1...
1/8
Do sequence variations in these paralogs change the ribosome function? Yes!
I am excited to share our new preprint @mbarnalab @jkpritch in collaboration with Calico:
www.medrxiv.org/content/10.1...
1/8
November 19, 2025 at 11:00 PM
Ribosomal RNA (rRNA) genes are found in hundreds of copies in the human genome.
Do sequence variations in these paralogs change the ribosome function? Yes!
I am excited to share our new preprint @mbarnalab @jkpritch in collaboration with Calico:
www.medrxiv.org/content/10.1...
1/8
Do sequence variations in these paralogs change the ribosome function? Yes!
I am excited to share our new preprint @mbarnalab @jkpritch in collaboration with Calico:
www.medrxiv.org/content/10.1...
1/8
Here's to something beautiful to start the day this Halloween Friday. I thought you might enjoy my spooky beautiful cat(tleya). ♥️
October 31, 2025 at 1:28 PM
Here's to something beautiful to start the day this Halloween Friday. I thought you might enjoy my spooky beautiful cat(tleya). ♥️
Today is the our @jacksonlab.bsky.social scientific symposium and faculty retreat, and I'm excited to hear about research being conducted by JAX trainee's and our institution's scientific trajectory. Love my research communities here in central Connecticut and Bar Harbor.
October 27, 2025 at 5:19 PM
Today is the our @jacksonlab.bsky.social scientific symposium and faculty retreat, and I'm excited to hear about research being conducted by JAX trainee's and our institution's scientific trajectory. Love my research communities here in central Connecticut and Bar Harbor.
On the last day of #ASHG25, attending a telomere session entitled "end results" seems fitting. It's been a great meeting talking with vibrant young geneticists, and on this note, I'm hiring a postdoc! thejacksonlaboratory.wd503.myworkdayjobs.com/External_JAX...
Postdoctoral Associate
The Beck Lab is seeking an enthusiastic, independent, and highly motivated postdoctoral fellow to join our innovative research group at the Jackson Laboratory for Genomic Medicine and University of Co...
thejacksonlaboratory.wd503.myworkdayjobs.com
October 18, 2025 at 2:45 PM
On the last day of #ASHG25, attending a telomere session entitled "end results" seems fitting. It's been a great meeting talking with vibrant young geneticists, and on this note, I'm hiring a postdoc! thejacksonlaboratory.wd503.myworkdayjobs.com/External_JAX...
Reposted by Christine Beck
I want to try something again at #ASHG25 this year: I'll block some time on Thursday and Friday afternoons to meet with trainees who would be interested to chat on any topic.
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
October 6, 2025 at 11:14 PM
I want to try something again at #ASHG25 this year: I'll block some time on Thursday and Friday afternoons to meet with trainees who would be interested to chat on any topic.
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
Kicking off the Annual Society of Human Genetics meeting in drizzly Boston with a program committee meeting! Welcome to #ASHG25, and hope to see your smiling, brilliant faces!
October 14, 2025 at 4:11 PM
Kicking off the Annual Society of Human Genetics meeting in drizzly Boston with a program committee meeting! Welcome to #ASHG25, and hope to see your smiling, brilliant faces!
Reposted by Christine Beck
My work today is sponsored by...
September 10, 2025 at 7:31 PM
My work today is sponsored by...
Reposted by Christine Beck
Hey Drosophilists: Might you maintain Fuyama's original gynogenetic "gyn-F9" (BDSC #5353) stock in your library?
The current stock from Bloomington is not producing progeny with ms(k81) males.
Thank you!!!
The current stock from Bloomington is not producing progeny with ms(k81) males.
Thank you!!!
August 24, 2025 at 11:36 AM
Hey Drosophilists: Might you maintain Fuyama's original gynogenetic "gyn-F9" (BDSC #5353) stock in your library?
The current stock from Bloomington is not producing progeny with ms(k81) males.
Thank you!!!
The current stock from Bloomington is not producing progeny with ms(k81) males.
Thank you!!!
Reposted by Christine Beck
It's exciting to see the continuing legacy of T2T sequencing methods being discussed on @scifri.bsky.social ! 🧬
Complete genomes are helping us understand more and more about genetic function and diversity in areas of our DNA that were unreadable just a few years ago.
Complete genomes are helping us understand more and more about genetic function and diversity in areas of our DNA that were unreadable just a few years ago.
Complete genomes alert! @glennislogsdon.bsky.social, @christinebeck.bsky.social, and I were on @scifri.bsky.social today talking about "Complex genetic variation in nearly complete human genomes"
📄 www.nature.com/articles/s41...
📻 www.sciencefriday.com/segments/65-...
📄 www.nature.com/articles/s41...
📻 www.sciencefriday.com/segments/65-...
65 Genomes Expand Our Picture Of Human Genetics
Researchers closely examined the genomes of 65 individuals to paint a more complex, and more complete, picture of human genetic diversity.
www.sciencefriday.com
August 1, 2025 at 9:11 PM
It's exciting to see the continuing legacy of T2T sequencing methods being discussed on @scifri.bsky.social ! 🧬
Complete genomes are helping us understand more and more about genetic function and diversity in areas of our DNA that were unreadable just a few years ago.
Complete genomes are helping us understand more and more about genetic function and diversity in areas of our DNA that were unreadable just a few years ago.
This was both fun and terrifying to tape! Awesome to talk with @glennislogsdon.bsky.social and @aphillippy.bsky.social about our sequencing data / paper, the improvements to large-scale sequencing projects, and what this means for our understanding of our DNA!
Complete genomes alert! @glennislogsdon.bsky.social, @christinebeck.bsky.social, and I were on @scifri.bsky.social today talking about "Complex genetic variation in nearly complete human genomes"
📄 www.nature.com/articles/s41...
📻 www.sciencefriday.com/segments/65-...
📄 www.nature.com/articles/s41...
📻 www.sciencefriday.com/segments/65-...
65 Genomes Expand Our Picture Of Human Genetics
Researchers closely examined the genomes of 65 individuals to paint a more complex, and more complete, picture of human genetic diversity.
www.sciencefriday.com
August 1, 2025 at 9:02 PM
This was both fun and terrifying to tape! Awesome to talk with @glennislogsdon.bsky.social and @aphillippy.bsky.social about our sequencing data / paper, the improvements to large-scale sequencing projects, and what this means for our understanding of our DNA!
Reposted by Christine Beck
Someone asked me just today if RSS is “still a thing”.
Friends, it definitely is! Though I will always sigh for google reader, RSS remains a fantastic way to pull in news from the sources you want to read, without “the algorithm” sucking you into rage and despair.
Friends, it definitely is! Though I will always sigh for google reader, RSS remains a fantastic way to pull in news from the sources you want to read, without “the algorithm” sucking you into rage and despair.
Newsletter: In a media landscape dominated by algorithmic feeds that aim to manipulate and extract, sometimes the most radical thing you can do is choose to read what you want, when you want, without anyone watching over your shoulder.
Here’s how to use RSS.
www.citationneeded.news/curate-with-...
Here’s how to use RSS.
www.citationneeded.news/curate-with-...
Curate your own newspaper with RSS
Escape newsletter inbox chaos and algorithmic surveillance by building your own enshittification-proof newspaper from the writers you already read
www.citationneeded.news
August 1, 2025 at 2:24 AM
Someone asked me just today if RSS is “still a thing”.
Friends, it definitely is! Though I will always sigh for google reader, RSS remains a fantastic way to pull in news from the sources you want to read, without “the algorithm” sucking you into rage and despair.
Friends, it definitely is! Though I will always sigh for google reader, RSS remains a fantastic way to pull in news from the sources you want to read, without “the algorithm” sucking you into rage and despair.
Reposted by Christine Beck
My wife assembled two complete human genomes and we couldn’t get that published anywhere.
Two papers in today's issue of @nature.com : 1) we assemble 65 genomes to near completion, including centromeres and the MHC. tinyurl.com/3huhax6w. 2) we sequence 1,019 genomes from the 1kGP with long reads, revealing SVs down to low allele frequencies tinyurl.com/wbx3we9x.
Complex genetic variation in nearly complete human genomes - Nature
Using sequencing and haplotype-resolved assembly of 65 diverse human genomes, complex regions including the major histocompatibility complex and centromeres are analysed.
tinyurl.com
July 25, 2025 at 12:47 PM
My wife assembled two complete human genomes and we couldn’t get that published anywhere.
Lovely write up on our paper from @jacksonlab.bsky.social. It's been <4 years since I joined the HGSVC, and together with Peter Audano and Parithi Balachandran in my lab, @tobiasmar.bsky.social, @glennislogsdon.bsky.social, and many others, we've done a lot. Here's to great collaborators!
New research, published today in @natureportfolio.nature.com, decodes the most elusive, difficult-to-sequence regions of the genome from populations around the world, rewriting knowledge of human biology and setting a new benchmark for precision medicine. 🧪🧬🔬
The most complete view of the human genome yet sets new standard for use in precision medicine
What if scientists unlocked the most hidden, hardest-to-read regions of our DNA?
www.jax.org
July 24, 2025 at 1:41 AM
Lovely write up on our paper from @jacksonlab.bsky.social. It's been <4 years since I joined the HGSVC, and together with Peter Audano and Parithi Balachandran in my lab, @tobiasmar.bsky.social, @glennislogsdon.bsky.social, and many others, we've done a lot. Here's to great collaborators!
Reposted by Christine Beck
Check out our latest work co-led by @dcsoto.bsky.social and @jmuribescr.bsky.social identifying hundreds of human duplicated gene families using the new T2T-CHM13 assembly, with a focus on those potentially contributing to brain evolution 🧪: authors.elsevier.com/a/1lTQtL7PXu...
authors.elsevier.com
July 21, 2025 at 4:26 PM
Check out our latest work co-led by @dcsoto.bsky.social and @jmuribescr.bsky.social identifying hundreds of human duplicated gene families using the new T2T-CHM13 assembly, with a focus on those potentially contributing to brain evolution 🧪: authors.elsevier.com/a/1lTQtL7PXu...
Reposted by Christine Beck
Are you bravely deciding to do a postdoc in the US? And also interested in some combination of genomics, immunology, and transposons? If so, consider applying to my lab at the BioFrontiers Institute in Boulder, Colorado!
jobs.colorado.edu/jobs/JobDeta...
🧪🧬 #TESky #interferosky
jobs.colorado.edu/jobs/JobDeta...
🧪🧬 #TESky #interferosky
July 17, 2025 at 7:36 PM
Are you bravely deciding to do a postdoc in the US? And also interested in some combination of genomics, immunology, and transposons? If so, consider applying to my lab at the BioFrontiers Institute in Boulder, Colorado!
jobs.colorado.edu/jobs/JobDeta...
🧪🧬 #TESky #interferosky
jobs.colorado.edu/jobs/JobDeta...
🧪🧬 #TESky #interferosky
Reposted by Christine Beck
Very happy to share our protocols paper for CELLO-seq. This will make single cell long read RNA-seq more accessible and provides analysis guidelines. We hope this helps the #transposon #TEsky community and folks working on #singleCell isoform and allelic #gene expression. doi.org/10.1038/s415...
Long-read RNA sequencing of transposable elements from single cells using CELLO-seq - Nature Protocols
Single-cell long-read RNA sequencing enables the high-fidelity mapping of single-cell expression data from highly sequence-similar transposable elements to unique genomic loci by correcting errors fro...
doi.org
July 16, 2025 at 4:55 PM
Very happy to share our protocols paper for CELLO-seq. This will make single cell long read RNA-seq more accessible and provides analysis guidelines. We hope this helps the #transposon #TEsky community and folks working on #singleCell isoform and allelic #gene expression. doi.org/10.1038/s415...
I has a monarch growing in my garden. That and the fireflies tonight have made my day more tolerable. What is keeping your head above water?
July 11, 2025 at 3:00 AM
I has a monarch growing in my garden. That and the fireflies tonight have made my day more tolerable. What is keeping your head above water?
Reposted by Christine Beck
They finally made the milk from that hotel
July 6, 2025 at 3:42 PM
They finally made the milk from that hotel
Reposted by Christine Beck
I am thrilled to announce that in January 2026 I will be starting my own lab at NYU Biology! Soon enough I will be recruiting postdocs and students! Please reach out if you are interested with a CV and description of your research interests, or if you know of people who could be interested! 🧬🗽 🦊
June 25, 2025 at 8:10 PM
I am thrilled to announce that in January 2026 I will be starting my own lab at NYU Biology! Soon enough I will be recruiting postdocs and students! Please reach out if you are interested with a CV and description of your research interests, or if you know of people who could be interested! 🧬🗽 🦊
Reposted by Christine Beck
🧬🌽 Happy Transposon Day! 🌽🧬
Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
June 16, 2025 at 3:14 PM
🧬🌽 Happy Transposon Day! 🌽🧬
Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
Completely germane to absolutely nothing, schadenfreude is my favorite Freud when it comes to certain people.
June 5, 2025 at 7:54 PM
Completely germane to absolutely nothing, schadenfreude is my favorite Freud when it comes to certain people.
There's only ~1 week left for abstract submission for #ASHG25! Get your best stories submitted so we have more fun planning the program. Looking forward to seeing a ton of you genetics researchers in Boston this fall.
June 2, 2025 at 2:06 PM
There's only ~1 week left for abstract submission for #ASHG25! Get your best stories submitted so we have more fun planning the program. Looking forward to seeing a ton of you genetics researchers in Boston this fall.
Reposted by Christine Beck
Kicking off Biology of Genomes with opening remarks by @tuuliel.bsky.social! @cshlnews.bsky.social #bog25
May 6, 2025 at 11:32 PM
Kicking off Biology of Genomes with opening remarks by @tuuliel.bsky.social! @cshlnews.bsky.social #bog25
Reposted by Christine Beck
“This doesn't feel like a strategic plan to reorganize and make the NIH better and more efficient. It feels like a wrecking ball,” says an NIH insider, who asked 60 Minutes to protect his identity due to his concern about reprisal. https://cbsn.ws/3EKcER9
April 27, 2025 at 11:54 PM
“This doesn't feel like a strategic plan to reorganize and make the NIH better and more efficient. It feels like a wrecking ball,” says an NIH insider, who asked 60 Minutes to protect his identity due to his concern about reprisal. https://cbsn.ws/3EKcER9