Max Gutierrez
@maxgg.bsky.social
Cell Biologist 🇦🇷&🇬🇧 at The Crick in London
Reposted by Max Gutierrez
🔬 TB, infectious disease & global health researchers: Save $250 by registering for the Keystone Symposium on Tuberculosis by Jan 22 (11:59 PM MST). Join leaders in TB biology & global health. 🎥 youtu.be/4L_N79rDCfw
🔗 keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #TBResearch
🔗 keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #TBResearch
KSQA: Dr. Max Gutierrez (Tuberculosis)
YouTube video by KeystoneSymposia
youtu.be
January 20, 2026 at 8:18 PM
🔬 TB, infectious disease & global health researchers: Save $250 by registering for the Keystone Symposium on Tuberculosis by Jan 22 (11:59 PM MST). Join leaders in TB biology & global health. 🎥 youtu.be/4L_N79rDCfw
🔗 keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #TBResearch
🔗 keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #TBResearch
Reposted by Max Gutierrez
0/10
🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology
Continuum architecture dynamics of vesicle tethering in exocytosis
www.cell.com/cell/fulltex...
🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology
Continuum architecture dynamics of vesicle tethering in exocytosis
www.cell.com/cell/fulltex...
Continuum architecture dynamics of vesicle tethering in exocytosis
Data from complementary imaging techniques were integrated into a model that resolves
the dynamic exocyst ensemble and membrane architecture during exocytosis, an essential
cellular pathway. Sec18 med...
www.cell.com
January 16, 2026 at 5:28 PM
0/10
🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology
Continuum architecture dynamics of vesicle tethering in exocytosis
www.cell.com/cell/fulltex...
🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology
Continuum architecture dynamics of vesicle tethering in exocytosis
www.cell.com/cell/fulltex...
Reposted by Max Gutierrez
🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰.
✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social
📖 shorturl.at/IDwza
👇 A short thread...
✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social
📖 shorturl.at/IDwza
👇 A short thread...
January 13, 2026 at 6:20 AM
🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰.
✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social
📖 shorturl.at/IDwza
👇 A short thread...
✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social
📖 shorturl.at/IDwza
👇 A short thread...
A great meeting ahead for host and pathogen aficionados! Keynote speakers: Florence Niedergang (Cochin) and Raphael Valdivia (Duke)- plenty of opportunities for early career researchers to present their work and a very collegial and supportive network. Belfast here we go! Please repost.
SAVE THE DATE!
The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast.
Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions.
Follow us to stay tuned! www.ukcellmicro.org
The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast.
Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions.
Follow us to stay tuned! www.ukcellmicro.org
January 12, 2026 at 6:34 PM
A great meeting ahead for host and pathogen aficionados! Keynote speakers: Florence Niedergang (Cochin) and Raphael Valdivia (Duke)- plenty of opportunities for early career researchers to present their work and a very collegial and supportive network. Belfast here we go! Please repost.
Reposted by Max Gutierrez
🧐”Study reveals how #tuberculosis exploits immune defenses to promote infection.”
🔗to study published in Science Immunology ⬇️
Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival
www.science.org/doi/10.1126/...
🔗to study published in Science Immunology ⬇️
Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival
www.science.org/doi/10.1126/...
January 11, 2026 at 3:49 PM
🧐”Study reveals how #tuberculosis exploits immune defenses to promote infection.”
🔗to study published in Science Immunology ⬇️
Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival
www.science.org/doi/10.1126/...
🔗to study published in Science Immunology ⬇️
Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival
www.science.org/doi/10.1126/...
Reposted by Max Gutierrez
Scientists at MRC CMM & collaborators discover how Mycobacterium tuberculosis harnesses the immune system to cause infection.
Gordon Brown @mrccmm.bsky.social Claire Hoving @uct-fhs-research.bsky.social @maxgg.bsky.social @crick.ac.uk @wellcometrust.bsky.social
Read more:
Gordon Brown @mrccmm.bsky.social Claire Hoving @uct-fhs-research.bsky.social @maxgg.bsky.social @crick.ac.uk @wellcometrust.bsky.social
Read more:
eur03.safelinks.protection.outlook.com
January 9, 2026 at 7:15 PM
Scientists at MRC CMM & collaborators discover how Mycobacterium tuberculosis harnesses the immune system to cause infection.
Gordon Brown @mrccmm.bsky.social Claire Hoving @uct-fhs-research.bsky.social @maxgg.bsky.social @crick.ac.uk @wellcometrust.bsky.social
Read more:
Gordon Brown @mrccmm.bsky.social Claire Hoving @uct-fhs-research.bsky.social @maxgg.bsky.social @crick.ac.uk @wellcometrust.bsky.social
Read more:
Reposted by Max Gutierrez
I am thrilled to share that the work from @maxgg.bsky.social team @crick.ac.uk engineering a lung-on-chip from human iPSC is published in #ScienceAdvances @science.org in the new year.
January 2, 2026 at 10:03 PM
I am thrilled to share that the work from @maxgg.bsky.social team @crick.ac.uk engineering a lung-on-chip from human iPSC is published in #ScienceAdvances @science.org in the new year.
Reposted by Max Gutierrez
I am happy to share that the work from @maxgg.bsky.social at @crick.ac.uk engineering a lung-on-chip from human iPSC is published in #ScienceAdvances @science.org in the new year.
January 3, 2026 at 1:48 PM
I am happy to share that the work from @maxgg.bsky.social at @crick.ac.uk engineering a lung-on-chip from human iPSC is published in #ScienceAdvances @science.org in the new year.
Very happy to see this out! Work led by
@jaksonluk.bsky.social together with an amazing team @crick.ac.uk Jakson et al established a scalable and reproducible multicellular system based on human stem cells to mimic the human alveolar space in a micro-physiological system. Congratulations everyone!👏
@jaksonluk.bsky.social together with an amazing team @crick.ac.uk Jakson et al established a scalable and reproducible multicellular system based on human stem cells to mimic the human alveolar space in a micro-physiological system. Congratulations everyone!👏
I am thrilled to share that the work from @maxgg.bsky.social team @crick.ac.uk engineering a lung-on-chip from human iPSC is published in #ScienceAdvances @science.org in the new year.
January 2, 2026 at 10:41 PM
Very happy to see this out! Work led by
@jaksonluk.bsky.social together with an amazing team @crick.ac.uk Jakson et al established a scalable and reproducible multicellular system based on human stem cells to mimic the human alveolar space in a micro-physiological system. Congratulations everyone!👏
@jaksonluk.bsky.social together with an amazing team @crick.ac.uk Jakson et al established a scalable and reproducible multicellular system based on human stem cells to mimic the human alveolar space in a micro-physiological system. Congratulations everyone!👏
Reposted by Max Gutierrez
Lab-grown lung models have traditionally been grown from a mixture of cells, making it hard to tell how a disease or treatment will affect an individual person.
These new models by @maxgg.bsky.social’s team and AlveoliX are grown from a single person’s stem cells ⤵️ www.crick.ac.uk/news/2026-01...
These new models by @maxgg.bsky.social’s team and AlveoliX are grown from a single person’s stem cells ⤵️ www.crick.ac.uk/news/2026-01...
Built to breathe: mini ‘lungs’ recreate individual response to infection
Lung-on-chip device exposes earliest stages of tuberculosis infection, and opens doors to investigate diversity in disease progression and personalised treatment.
www.crick.ac.uk
January 1, 2026 at 7:58 PM
Lab-grown lung models have traditionally been grown from a mixture of cells, making it hard to tell how a disease or treatment will affect an individual person.
These new models by @maxgg.bsky.social’s team and AlveoliX are grown from a single person’s stem cells ⤵️ www.crick.ac.uk/news/2026-01...
These new models by @maxgg.bsky.social’s team and AlveoliX are grown from a single person’s stem cells ⤵️ www.crick.ac.uk/news/2026-01...
Reposted by Max Gutierrez
Last couple of days to vote for your favourite 'Featured image' from 2025 ❤️🔬!
focalplane.biologists.com/2025/12/19/v...
focalplane.biologists.com/2025/12/19/v...
December 29, 2025 at 11:23 AM
Last couple of days to vote for your favourite 'Featured image' from 2025 ❤️🔬!
focalplane.biologists.com/2025/12/19/v...
focalplane.biologists.com/2025/12/19/v...
Pre-Christmas vibes at @crick.ac.uk 🎄
December 22, 2025 at 9:39 PM
Pre-Christmas vibes at @crick.ac.uk 🎄
Reposted by Max Gutierrez
‘Why solutions to antimicrobial resistance are urgently needed‘ sergemostowylab.bsky.social & I had the opportunity to write an editorial for @dmmjournal.bsky.social ‘s collection celebrating 100 years of @biologists.bsky.social you can read it here: journals.biologists.com/dmm/article/...
Why solutions to antimicrobial resistance are urgently needed
Summary: This Editorial discusses the growing global problem of antimicrobial resistance, and new and emerging opportunities for developing real-world solutions, involving both basic science and clini...
journals.biologists.com
December 19, 2025 at 11:46 AM
‘Why solutions to antimicrobial resistance are urgently needed‘ sergemostowylab.bsky.social & I had the opportunity to write an editorial for @dmmjournal.bsky.social ‘s collection celebrating 100 years of @biologists.bsky.social you can read it here: journals.biologists.com/dmm/article/...
Reposted by Max Gutierrez
We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development.
www.nature.com/articles/s41...
A thread.
www.nature.com/articles/s41...
A thread.
Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids - Nature Communications
Here, the authors show that Mycobacterium tuberculosis manipulates lipid metabolism to overcome host restriction, by remodelling its lipidome and utilising host lipids as an alternative phosphate sour...
www.nature.com
December 22, 2025 at 1:11 PM
We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development.
www.nature.com/articles/s41...
A thread.
www.nature.com/articles/s41...
A thread.
Reposted by Max Gutierrez
Of course I like all the papers that we publish, but this is actually a very cool story, a great example of 'bush mechanics' in mycobacteria.
A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis | mBio journals.asm.org/doi/10.1128/...
A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis | mBio journals.asm.org/doi/10.1128/...
A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis | mBio
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains the world’s deadliest bacterial infection, in part because the bacterium’s
unique cell envelope makes it highly resistant to antibioti...
journals.asm.org
December 13, 2025 at 8:28 AM
Of course I like all the papers that we publish, but this is actually a very cool story, a great example of 'bush mechanics' in mycobacteria.
A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis | mBio journals.asm.org/doi/10.1128/...
A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis | mBio journals.asm.org/doi/10.1128/...
Academia is just a job. And you need 29.95 quid to find out why...
December 11, 2025 at 7:45 AM
Academia is just a job. And you need 29.95 quid to find out why...
Reposted by Max Gutierrez
📢 Early-Career TB Researchers: Submit short talk abstracts & scholarship apps by Nov. 24! Join us Mar 23-26, 2026 in Cape Town for cutting-edge TB & global health. 🎥Highlights: youtu.be/YcKVeGWqXSM
Submit: keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #tuberculosis #TB
Submit: keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #tuberculosis #TB
Tuberculosis Meeting Promo
YouTube video by KeystoneSymposia
youtu.be
November 21, 2025 at 10:01 PM
📢 Early-Career TB Researchers: Submit short talk abstracts & scholarship apps by Nov. 24! Join us Mar 23-26, 2026 in Cape Town for cutting-edge TB & global health. 🎥Highlights: youtu.be/YcKVeGWqXSM
Submit: keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #tuberculosis #TB
Submit: keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #tuberculosis #TB
In the era of chatGPT, Claude, Grok, DeepSeek, Perplexity etc and finding an email in outlook using keywords is literally impossible….
November 21, 2025 at 8:08 PM
In the era of chatGPT, Claude, Grok, DeepSeek, Perplexity etc and finding an email in outlook using keywords is literally impossible….
👇👇Last days to submit your abstract to be considered for a short talk! Deadline 24 November!https://www.keystonesymposia.org/conferences/conference-listing/meeting/travel/c42026
Tuberculosis: Understanding the Disease Across Scales | Keystone Symposia
Join us at the Keystone Symposia on Tuberculosis: Understanding the Disease Across Scales, March 2026, in Cape Town, with field leaders!
www.keystonesymposia.org
November 19, 2025 at 8:48 PM
👇👇Last days to submit your abstract to be considered for a short talk! Deadline 24 November!https://www.keystonesymposia.org/conferences/conference-listing/meeting/travel/c42026
...Students will need to develop sufficient expertise to identify when AI systems produce plausible but incorrect outputs — which poses a dilemma because this requires the very skills that AI is starting to replace...
www.nature.com/articles/d41...
www.nature.com/articles/d41...
PhD training needs a reboot in an AI world
As machines get better at data analysis and writing tasks, doctoral training must evolve to make the most of artificial-intelligence outputs.
www.nature.com
November 9, 2025 at 9:54 PM
...Students will need to develop sufficient expertise to identify when AI systems produce plausible but incorrect outputs — which poses a dilemma because this requires the very skills that AI is starting to replace...
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Max Gutierrez
Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...
VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair
Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach,...
www.biorxiv.org
October 25, 2025 at 1:11 PM
Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...
Reposted by Max Gutierrez
Crick group leaders work across disciplines, supported by core funding and mentoring to build ambitious, curiosity-driven research.
Apply now to join us ➡️ www.crick.ac.uk/careers-stud...
Apply now to join us ➡️ www.crick.ac.uk/careers-stud...
October 27, 2025 at 2:07 PM
Crick group leaders work across disciplines, supported by core funding and mentoring to build ambitious, curiosity-driven research.
Apply now to join us ➡️ www.crick.ac.uk/careers-stud...
Apply now to join us ➡️ www.crick.ac.uk/careers-stud...
Reposted by Max Gutierrez
🚨 We’re hiring a postdoc! 🚨
Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab!
Reach out directly: [email protected]
Learn more: bonetponcelab.com
Let’s chat!
Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab!
Reach out directly: [email protected]
Learn more: bonetponcelab.com
Let’s chat!
October 14, 2025 at 5:00 PM
🚨 We’re hiring a postdoc! 🚨
Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab!
Reach out directly: [email protected]
Learn more: bonetponcelab.com
Let’s chat!
Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab!
Reach out directly: [email protected]
Learn more: bonetponcelab.com
Let’s chat!
Reposted by Max Gutierrez
New paper - MAPL strikes again! Interested in mitochondrial signalling, inflammation, lysosome biology, pyroptosis, and Parkinson's disease? Have a look, there's something for everyone! Feeling grateful! @mitocollier.bsky.social Funded by #CIHR, @asapresearch.parkinsonsroadmap.org.
rdcu.be/eKKz1 🇨🇦
rdcu.be/eKKz1 🇨🇦
October 14, 2025 at 11:50 AM
New paper - MAPL strikes again! Interested in mitochondrial signalling, inflammation, lysosome biology, pyroptosis, and Parkinson's disease? Have a look, there's something for everyone! Feeling grateful! @mitocollier.bsky.social Funded by #CIHR, @asapresearch.parkinsonsroadmap.org.
rdcu.be/eKKz1 🇨🇦
rdcu.be/eKKz1 🇨🇦
Reposted by Max Gutierrez
WHO reports 1 in 6 bacterial infections worldwide are antibiotic-resistant, with resistance rising sharply since 2018. Gram-negative bacteria like E. coli and K. pneumoniae pose the biggest threat. Action on #AMR surveillance and responsible antibiotic use is needed.
www.who.int/news/item/13...
www.who.int/news/item/13...
WHO warns of widespread resistance to common antibiotics worldwide
One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments, according to a new World Health Organization (WHO) r...
www.who.int
October 13, 2025 at 11:09 AM
WHO reports 1 in 6 bacterial infections worldwide are antibiotic-resistant, with resistance rising sharply since 2018. Gram-negative bacteria like E. coli and K. pneumoniae pose the biggest threat. Action on #AMR surveillance and responsible antibiotic use is needed.
www.who.int/news/item/13...
www.who.int/news/item/13...