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Reposted by Max Gutierrez

Ben Engel @cellarchlab.com · 8d

EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬

The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩‍🔬🤓

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Reposted by Max Gutierrez

Olivier Neyrolles @oneyrolles.bsky.social · 15d

Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org!
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC

Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance | PNAS

Tuberculosis remains the deadliest infectious disease caused by a single pathogen, highlighting the urgent need for novel therapies. A deeper under...

www.pnas.org

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Max Gutierrez @maxgg.bsky.social · 17d

What I would tell my younger self if I could go back in time: enjoy life as in 2025 you will be mostly charging devices, downloading apps and updating software…

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Reposted by Max Gutierrez

Enninga Lab @enningalab.bsky.social · 20d

🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 20d

Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1

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Reposted by Max Gutierrez

The Francis Crick Institute @crick.ac.uk · 28d

Watch @maxgg.bsky.social, Group Leader at the Crick, as he explains what happens to cells that are infected with tuberculosis and how his lab is studying our bodies’ response to this infection.
www.youtube.com/watch?v=VWCt...

Researching the World’s Deadliest Infectious Disease – with Maximiliano Gutierrez

YouTube video by Francis Crick Institute

www.youtube.com

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Max Gutierrez @maxgg.bsky.social · 29d

rupress.org/jcb/article/...

ATG16L1 controls mammalian vacuolar proton ATPase

Duque et al. report a hitherto unappreciated function of ATG16L1, best known for its roles in canonical autophagy and membrane atg8ylation, in directly reg

rupress.org

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Max Gutierrez @maxgg.bsky.social · Aug 12

Wonderful and important work Giulia! Congratulations!

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Reposted by Max Gutierrez

Giulia Paci @giuliapaci.bsky.social · Aug 11

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

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Max Gutierrez @maxgg.bsky.social · Aug 6

Congrats Rashmi and the team! Beautiful work! 👏

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Max Gutierrez @maxgg.bsky.social · Jul 31

A first-in-class cell-wall biosynthesis inhibitor in #TB www.nature.com/articles/s41...

SuFEx-based antitubercular compound irreversibly inhibits Pks13 - Nature

A preclinical covalent compound, CMX410, contains a aryl fluorosulfate warhead that targets the acyltransferase domain of Mtb Pks13, an essential enzyme in cell-wall biosynthesis, making it a pro...

www.nature.com

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Reposted by Max Gutierrez

Katie Downes @dr-downes.bsky.social · Jul 30

Very excited to announce that my first, first author paper, is now on BioRxiv! In this paper we unambiguously show #COPII coated vesicles in unperturbed human cells for the very first time!!

Make my day and check it out!
www.biorxiv.org/content/10.1...

#Cryo-ET #TeamTomo #Cryo-CLEM ❄️🔬❄️🔬❄️🔬❄️🔬

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Reposted by Max Gutierrez

Michael Glickman @michaelglickman.bsky.social · Jul 28

Happy to share the most recent preprint from the lab, the thesis work of Dr. Adam Krebs and a collaboration with many, including the Geissmann lab @mskcancercenter.bsky.social
Here is a short paper thread. #tuberculosis #macrophages 🦠
www.biorxiv.org/content/10.1...

Human iPSC derived alveolar macrophages reveal macrophage subtype specific functions of itaconate in M. tuberculosis host defense

M. tuberculosis must survive within multiple macrophage populations during infection, including alveolar macrophages (AM) and recruited inflammatory macrophages. In mice, itaconate, produced in macrop...

www.biorxiv.org

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Reposted by Max Gutierrez

Max Perutz Labs Vienna @maxperutzlabs.ac.at · Jul 23

📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Mechanistic Cell and Developmental Biology. More details ➡️ tinyurl.com/3fbkp89c

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Reposted by Max Gutierrez

Andreas Bäumler @abaumler.bsky.social · Jul 22

Meet the new Editor in Chief of mSystems journals.asm.org/doi/10.1128/...

Humanity’s urgent challenges need solutions from systems microbiology | mSystems

It is with great excitement and sincere dedication that I assume the role of editor in chief of mSystems. Building on the momentum and reputation that mSystems has achieved in its first decade, we wil...

journals.asm.org

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Reposted by Max Gutierrez

Bryan Bryson @thebrysonlab.bsky.social · Jul 21

Newest paper from the lab out today (doi.org/10.1084/jem....)! Here, we describe PathMHC, a novel MS-based approach to identify rare pathogen-derived peptides on MHC-I and MHC-II. We apply this to a range of pathogens Mtb, SARS-CoV-2, and Listeria.

Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery

MS-based immunopeptidomics can facilitate vaccine antigen discovery, but self-MHC peptides greatly outnumber pathogen-derived MHC peptides, presenting a ch

doi.org

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Max Gutierrez @maxgg.bsky.social · Jul 11

I’ve heard things like, yeah these old classics from the 90’s… 😂

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Max Gutierrez @maxgg.bsky.social · Jul 7

The magic of Mafalda by the great Joaquin Lavado (Quino)- the mendocino did indeed galvanised a generation @newyorker.com Lahttps://www.newyorker.com/magazine/2025/07/07/the-argentinean-comic-strip-that-galvanized-a-generation

The Argentinean Comic Strip That Galvanized a Generation

How the politically aware six-year-old heroine of “Mafalda” became an international phenomenon.

www.newyorker.com

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Reposted by Max Gutierrez

Norwegian Centre for Molecular Biosciences and Medicine (NCMBM) @ncmbm.bsky.social · Jun 30

📣 We’re recruiting 1-2 Group Leaders! NCMBM is looking for early-career researchers ready to establish their independent research groups!

🧬 With an attractive start-up package, help us shape the future of molecular biosciences and medicine in 🇳🇴 and be part of the @nordicembl.bsky.social!

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Reposted by Max Gutierrez

Florence Niedergang @florenceniedergang.bsky.social · Jul 2

Thrilled to share that our "Poster at a Glance" on #Phagocytosis is out! Thank you @jcellsci.bsky.social @biologists.bsky.social for the invitation ! Prepared with @manondepierre.bsky.social @chiarapompili.bsky.social from @institutcochin.bsky.social journals.biologists.com/jcs/article/...

Phagocytosis at a glance

Summary: Phagocytosis involves receptor-driven actin and membrane remodelling to engulf microbes and debris. The phagosome then matures for degradation, supporting both nutrition and immune responses.

journals.biologists.com

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Reposted by Max Gutierrez

Kimberly Kline 🏔 @kimingeneva.bsky.social · Jul 3

🔬Calling all microbiologists. 🔬 Ever feel like your paper is too small for some journals, but too solid to sit on?
#FEMSMicrobes welcomes well-executed microbiology manuscripts, and they put special attention on promoting ECR authors, eg the webinar below. 👇 @femsjournals.bsky.social @femsmicro.org

FEMS Journals @femsjournals.bsky.social · May 7

Secure your spot for the #FEMSMicrobes Webinar today 🚨. You’ll deep dive into emerging breakthroughs in the field, from antimicrobial discovery to protein profiling to gut fungi imaging. Big insights for health, industry, and environment. 🦠

Register now: buff.ly/7nFyEIj

#FEMSWebinar #Microbes

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Max Gutierrez @maxgg.bsky.social · Jul 1

did you check the second link?

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Max Gutierrez @maxgg.bsky.social · Jul 1

💥 Very excited to share this review in Nature Reviews Microbiology.
Contributing to this review with Val, Digby and Amy was an enlightening experience! Hope people in the community find it useful- we managed to cite around 200 papers...
www.nature.com/articles/s41...
www.nature.com/articles/s41...

Mycobacterium tuberculosis biology, pathogenicity and interaction with the host

Nature Reviews Microbiology - In this Review, Warner, Barczak, Gutierrez and Mizrahi explore essential aspects of Mycobacterium tuberculosis physiology and biology, present recent advances related...

www.nature.com

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Reposted by Max Gutierrez

Gabriele Pollara @gpollara.bsky.social · Jun 19

🎯 New antibiotic target in TB!
👉 Small-molecule inhibitor targeting PurF, the first enzyme in the mycobacterial de novo purine biosynthesis pathway.
👉 Effective vs drug-resistant Mycobacterium tuberculosis in vivo (in mice)
#TBSky #IDSky #MedSky 🧪
@nature.com
www.nature.com/articles/s41...

Targeting de novo purine biosynthesis for tuberculosis treatment - Nature

The validation of inhibitors targeting PurF, a novel drug target for tuberculosis drug discovery, is described.

www.nature.com

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Reposted by Max Gutierrez

Esteban Hoijman @estebanhoijman.bsky.social · Jun 18

How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story:
www.cell.com/cell-host-mi...

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Max Gutierrez @maxgg.bsky.social · Jun 16

‼️ Save the date! ‼️ Tuberculosis: Understanding the Disease Across Scales Keystone 2026 on March 23-26 in Cape Town, South Africa 🇿🇦 Very excited to organise this meeting with Digby, Bree and Margarida
Short Talk Abstract Deadline: Nov. 24, 2025
www.keystonesymposia.org/conferences/...

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