Giulia Paci
@giuliapaci.bsky.social
610 followers 600 following 45 posts
Physicist having a go at biology, EMBO postdoctoral fellow @UCL in the Mao group, @EMBL alumna
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giuliapaci.bsky.social
Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️
Reposted by Giulia Paci
dev-journal.bsky.social
Pathway to Independence: a forecast for the future of developmental biology

In this Perspective, each of our 2025 Pathway to Independence Fellows discuss future outlooks for #DevBio and how their work will contribute to this exciting new era.

journals.biologists.com/dev/article/...
Picture of the title of the article and author list (2025 PI fellows) Chee Kiang Ewe, Max S. Farnworth, Anzy Miller, Joaquı́n Navajas Acedo, Marlies E. Oomen, Giulia Paci, Sonya A. Widen and Toshimichi Yamada
Reposted by Giulia Paci
nmoris.bsky.social
Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏

www.crick.ac.uk/careers-stud...
Moris Lab | Investigating human trunk development using stem cell-based embryo models
www.crick.ac.uk
Reposted by Giulia Paci
biig-ucl.bsky.social
Next BIIG seminar is 12-1pm on Friday 10th October 🔬😄:

- Anna Bajur (Imperial College London): “Quantifying cellular forces, one molecule at a time”
- Virginia Silio (UCL): “Euro-BioImaging: From Access to Analysis”
Reposted by Giulia Paci
thibautbrunet.bsky.social
Latest from ours: www.cell.com/cell-reports...

This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
Reposted by Giulia Paci
gautamdey.bsky.social
If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.

I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
Reposted by Giulia Paci
tunglejic.bsky.social
Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!
johninnescentre.bsky.social
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
Reposted by Giulia Paci
flybase.bsky.social
There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila
FlyBase Update – October 2025
The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support:
	•	European labs: Please consider contributing to the Cambridge, U.K. FlyBase group
	•	U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups
	•	Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience.
For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase
Reposted by Giulia Paci
katecavanaugh.bsky.social
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
Reposted by Giulia Paci
sarahmackattack.bsky.social
Getting ready for a presentation about Skype a Scientist, so I was crunching the numbers on what we've done this year & no wonder I'm tired.

Philly event attendees: 433
Zines distributed: 5,900
Seed packets distributed: 10,000
Online event attendees: 1,355
Classrooms matched w/scientists: 3,488
A ppt slide that says "weaving science into everyday" with 6 examples, including "getting coffee, at a street festival, trick or treating, on the road, at a community meeting, at the corner bar" and each of those has a picture associated like a squid zine at coffee, a table of squid stuff with a man dressed as a squid for street festival, squid postcards and candy for trick or treating, the squidmobile for road, me taking in front of people for community meeting, and bar coasters for corner bar
Reposted by Giulia Paci
merianelion.bsky.social
🚨Preprint🚨
What started as an attempt to compare CT scans of diverse fly brains, ended up a new concept for analysis & segmentation of difficult tomographic data. No ground truths, no training, just maths. This is TopoTome, topological data analysis of 3D images

www.biorxiv.org/content/10.1...
Figure showing 3 panels. Panel A: workflow of a classical deep learning model vs TopoTome workflow, with marked differences between the methods, including manual segmentation of images, design and optimization of neural network and data post processing that is needed in deep learning workflow but not in TopoTome. Panel B: core concepts behind TopoTome shown connected by arrows. From left to right, there is a microCT scan of a fly brain (3D reconstruction), a persistence barcode of H2 homologies, an image of how persistent barcodes map to the original CT brain scan, and a segmentation of a CT scan. Panel C shows the concept of cubical complex filtration of 2D and 3D image data.
Reposted by Giulia Paci
joachimgoedhart.bsky.social
Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...
Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm
Reposted by Giulia Paci
djcohen.bsky.social
So: can a cell hold hands with itself…and do we care? YES and YES! Read on to learn WHY, HOW, and what this has to do with…PARIS (and tree-hugging)? Swansong of Dr. Anamika; Hannah Kim on drums; and fantastic undergrads (Margaret/Lauren) ! 1/n
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Giulia Paci
biozentrum.unibas.ch
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
Reposted by Giulia Paci
superresolusian.bsky.social
BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...
Bioimage Analysis Specialist | King's College London
www.kcl.ac.uk
Reposted by Giulia Paci
felixmendu.bsky.social
Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio

meetings.embo.org/event/26-org...
Intracellular mechanics and organelle mechanobiology
Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…
meetings.embo.org
Reposted by Giulia Paci
gcharras.bsky.social
Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.

More here: elifesciences.org/reviewed-pre...
elifesciences.org
Reposted by Giulia Paci
wkhuber.bsky.social
Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?

Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Giulia Paci
rashmi-priya.bsky.social
Development does not happen in isolation! Material properties, geometry, stiffness, fluid flows...can all steer how development unfolds. If you’re exploring these kinds of questions, we’d love to see your work @dev-journal.bsky.social
More info below ⬇️
dev-journal.bsky.social
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells

Guest Editors: Alex Hughes and Rashmi Priya

📅 Deadline: 1 March 2026

journals.biologists.com/dev/pages/ex...

#DevBio
Reposted by Giulia Paci
fly-jedi.bsky.social
Dear JEDIs,
as we are self-organizing using the #EDRC as a nucleator we decided it is time for a JEDI database to boost our network! If you identify as a JEDI, please contact us here or send a mail to [email protected] to be added to our database.
#Drosophila
@fly-eds.bsky.social
Reposted by Giulia Paci
edrc2025.bsky.social
Three fantastic keynote lectures to kick off #EDRC2025 Lucia Prieto-Godiño @crick.ac.uk the @embo.org sponsored lecture, Romain Levayer @pasteur.fr and Marta Llimargas @ibmb-csic.bsky.social