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Reposted by Marlies Oomen

Margarida Cardoso Moreira @margaridamcm.bsky.social · 1d

Interested in understanding how new cell types evolve? Consider joining our group for a PhD!

The Francis Crick Institute @crick.ac.uk · 1d

2026 PhD recruitment is now open.

As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website:

www.crick.ac.uk/careers-stud...

PhD student recruitment

PhD recruitment information.

www.crick.ac.uk

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Reposted by Marlies Oomen

Development @dev-journal.bsky.social · 1d

Pathway to Independence: a forecast for the future of developmental biology

In this Perspective, each of our 2025 Pathway to Independence Fellows discuss future outlooks for #DevBio and how their work will contribute to this exciting new era.

journals.biologists.com/dev/article/...

Picture of the title of the article and author list (2025 PI fellows) Chee Kiang Ewe, Max S. Farnworth, Anzy Miller, Joaquı́n Navajas Acedo, Marlies E. Oomen, Giulia Paci, Sonya A. Widen and Toshimichi Yamada

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Reposted by Marlies Oomen

Raquel Fueyo @fueyoraquel.bsky.social · 2d

⚡⚡Excited to announce I'll be starting my lab at the Max Planck Institute of Molecular Genetics (@molgen.mpg.de) in Berlin in December! Leaving sunny California to join a fantastic environment with colleagues who do super cool work.
🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab

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Reposted by Marlies Oomen

Raquel Fueyo @fueyoraquel.bsky.social · 7d

Today in @nature.com, we present our work leveraging functional genomics and human blastoids to uncover a human-specific mechanism in preimplantation development driven by the endogenous retrovirus HERVK.
Special thanks to the reviewers whose comments improved our manuscript a lot! rdcu.be/eI3tD

A human-specific regulatory mechanism revealed in a pre-implantation model

Nature - Genetic manipulation of blastoids reveals the role of recently emerged transposable elements and genes in human development.

rdcu.be

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Reposted by Marlies Oomen

James Briscoe @jamesbriscoe.bsky.social · 8d

Meet the 2025 cohort of @dev-journal.bsky.social Pathway to Independence fellows

Read about the scientific visions of eight dev bio post-docs entering the academic job market

journals.biologists.com/dev/article/...

Pathway to Independence: a forecast for the future of developmental biology

ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

journals.biologists.com

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Reposted by Marlies Oomen

Ethan (Chee Kiang) Ewe @ethanewe.bsky.social · 8d

So glad to be among these good eggs, as @mads100tist.bsky.social once called us!

MwahahahahahadScientist @mads100tist.bsky.social · 8d

It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...

Pathway to Independence: a forecast for the future of developmental biology

ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

journals.biologists.com

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Reposted by Marlies Oomen

Anzy Miller @anzymiller.bsky.social · 8d

If you want to know why we should care about protein expression dynamics have a read of the perspective piece I wrote for @dev-journal.bsky.social. While you're there check out my fellow Pathway to Independence fellows' interesting pieces!
journals.biologists.com/dev/article/...

Pathway to Independence: a forecast for the future of developmental biology

ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

journals.biologists.com

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Reposted by Marlies Oomen

Max Farnworth @maxfarnworth.bsky.social · 8d

Together with my other wonderful 2025 PI fellows @biologists.bsky.social @dev-journal.bsky.social, I offer a perspective about the future of my respective field. Have a read - spoiler alert: its about brain evolution and neural lineages (I know - SHOCKER).

journals.biologists.com/dev/article/...

Pathway to Independence: a forecast for the future of developmental biology

ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

journals.biologists.com

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Marlies Oomen @marliesoomen.bsky.social · 8d

In need of a positive outlook on the future (of developmental biology)? Read our perspectives by my fellow @dev-journal.bsky.social PI fellows and myself. I'm hoping my future will contain much more TE biology and mammalian genome regulation!

journals.biologists.com/dev/article/...

Pathway to Independence: a forecast for the future of developmental biology

ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

journals.biologists.com

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Reposted by Marlies Oomen

MwahahahahahadScientist @mads100tist.bsky.social · 8d

With perspectives from my esteemed colleagues @ethanewe.bsky.social @maxfarnworth.bsky.social @anzymiller.bsky.social @marliesoomen.bsky.social @giuliapaci.bsky.social @sonyawiden.bsky.social and Toshimichi Yamada 🧪RNAs of all kinds, junk, jumping, and fluctuating genes, cells&tissues with opinions!

MwahahahahahadScientist @mads100tist.bsky.social · 8d

It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...

Pathway to Independence: a forecast for the future of developmental biology

ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

journals.biologists.com

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Reposted by Marlies Oomen

Job Dekker @jobdekker.bsky.social · 15d

New work from my lab with the Brown lab on how genome folding changes during motor neuron maturation, and how this process goes awry in ALS motor neurons. Led by Dr. Ozgun Uyan.
www.biorxiv.org/content/10.1...

Dynamic changes in chromosome and nuclear architecture during maturation of normal and ALS C9orf72 motor neurons

We have investigated changes in chromosome conformation, nuclear organization, and transcription during differentiation and maturation of control and mutant motor neurons harboring hexanucleotide expa...

www.biorxiv.org

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Reposted by Marlies Oomen

Rafael D. Acemel @rdacemel.bsky.social · 19d

Excited to post my first #JobOffer! I am looking for a research technician to help me build new projects from the grounds up at @cabd-upo-csic.bsky.social
We will use medaka to study how organs can be reprogrammed!
Details on how to apply below 👇
#JobOffer #ScienceJobs #EvoDevo #GeneRegulation

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Reposted by Marlies Oomen

the Node @the-node.bsky.social · 26d

ICYMI, the recordings of our #DevPres webinar on gene regulation are now available.
Check out the talks from @dev-journal.bsky.social PI fellows Anzy Miller @anzymiller.bsky.social and Marlies Oomen @marliesoomen.bsky.social.
thenode.biologists.com/catch-up-on-...
#devbio 🎥

Catch up on Development presents… webinar on gene regulation - the Node

Catch up on the Development presents... gene regulation webinar, featuring talks from two of Development's PI fellows.

thenode.biologists.com

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Reposted by Marlies Oomen

Raquel Garza @raquelgarza.bsky.social · Sep 8

💥 New preprint! 💥
We show that transposons are directly linked to a cell-type and region specific inflammatory state in Parkinson’s Disease 🧠🦠

What a team @jakobssonasap.bsky.social! Funded by @asapresearch.parkinsonsroadmap.org

#Parkinsons #Neuroinflammation #TEworldwide #singlecell #TEs

Johan Jakobsson @jakobssonlab.bsky.social · Sep 7

New preprint from my lab! We describe how transposable elements are activated in Parkinson’s disease, which is linked to an interferon response. We believe this study significantly advances our understanding of transposons and their role in human brains.

www.biorxiv.org/content/10.1...

Activation of transposable elements is linked to a region- and cell-type-specific interferon response in Parkinson's disease

Parkinson's disease (PD) is a common age-related neurodegenerative disorder involving a neuroinflammatory response, the cause of which remains unclear. Transposable elements (TE) have been linked to i...

www.biorxiv.org

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Reposted by Marlies Oomen

Bas van Steensel lab (NKI) @basvansteensellab.bsky.social · Sep 2

Very proud of our paper on "scrambling-by-hopping" LADs, which was just published: www.nature.com/articles/s41.... Congrats to Lise Dauban and the rest of the team – this was a real tour-de-force!

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Marlies Oomen @marliesoomen.bsky.social · Aug 26

Thank you for the interview @dev-journal.bsky.social! Very excited to be part of the Pathway to Independence program

Interested in my research? I'll be presenting my postdoc work at the 'Development presents' webinar, tomorrow afternoon: thenode.biologists.com/development-...

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Reposted by Marlies Oomen

Raquel Garza @raquelgarza.bsky.social · Aug 24

Excited to share our latest work!! 🌟🌟

Thank you for all the amazing work and congratulations to @anitaada.bsky.social and all the coauthors! 🍾

Johan Jakobsson @jakobssonlab.bsky.social · Aug 23

New paper from our lab! We found that LINE-1 transposons contribute to early human brain development.

Funded by @asapresearch.parkinsonsroadmap.org

www.cell.com/cell-genomic...

LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development

Adami et al. demonstrate that evolutionarily young L1s are expressed in human pluripotent stem cells and are dynamically regulated throughout neural differentiation. The study examines the role of L1s...

www.cell.com

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Marlies Oomen @marliesoomen.bsky.social · Aug 22

And if you're interested in my academic path, scientific interests and plans for the future; I had a great conversation with @katiepickup.bsky.social @dev-journal.bsky.social as part of the Pathway to Independence program: doi.org/10.1242/dev....

Pathway to Independence – an interview with Marlies Oomen

Marlies Oomen is a Postdoctoral Fellow at Helmholtz Munich, Germany, in the laboratory of Maria-Elena Torres-Padilla. She is interested in how transposable elements are involved in gene regulation acr...

journals.biologists.com

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Marlies Oomen @marliesoomen.bsky.social · Aug 22

Interested in transposable elements in mammalian preimplantation development? It's not too late to register for the 'Development presents' webinar next Wednesday. Together with Anzy @anzymiller.bsky.social who will talk about her postdoc work as well!

Development @dev-journal.bsky.social · Aug 14

Our next #DevPres webinar focusses on gene regulation with talks from 2025 Development PI fellows Anzy Miller @anzymiller.bsky.social and Marlies Oomen @marliesoomen.bsky.social, chaired by James Gahan @jgahan.bsky.social.
📆 27 August, 15:00 BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...

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Reposted by Marlies Oomen

the Node @the-node.bsky.social · Aug 21

Two of Development’s PI fellows, Anzy Miller @anzymiller.bsky.social and Marlies Oomen @marliesoomen.bsky.social, will be giving talks in our upcoming #DevPres webinar on gene regulation.

🗓️Wednesday 27 August, 15:00 BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

the Node @the-node.bsky.social · Aug 21

Meet Development’s 2025 Pathway to Independence (PI) fellows

In a series of interviews published in @dev-journal.bsky.social, we learn more about each fellow’s career path, research interests and aspirations when they start their own lab.

thenode.biologists.com/developments...

Development's Pathway to Independence programme: meet the 2025 fellows - the Node

Earlier in 2025, we welcomed our third cohort of Development's Pathway to Independence (PI) fellows - researchers whom we will be supporting as they

thenode.biologists.com

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Reposted by Marlies Oomen

Nature Reviews Genetics @natrevgenet.nature.com · Aug 18

Our featured article:
Epigenome dynamics in early mammalian embryogenesis by Adam Burton & Maria-Elena Torres-Padilla go.nature.com/45UA8Ob

Epigenome dynamics in early mammalian embryogenesis - Nature Reviews Genetics

Upon fertilization and during early mammalian development, major changes in cellular plasticity occur. This is accompanied by large-scale epigenome remodelling, as has been recently highlighted by the...

go.nature.com

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Reposted by Marlies Oomen

Anzy Miller @anzymiller.bsky.social · Aug 18

Interested in how cells read biological time? Next week I'm talking about my recently published work on how protein expression oscillations are read by cells and their impact on the timing of cell differentiation. Link below to register!

Development @dev-journal.bsky.social · Aug 14

Our next #DevPres webinar focusses on gene regulation with talks from 2025 Development PI fellows Anzy Miller @anzymiller.bsky.social and Marlies Oomen @marliesoomen.bsky.social, chaired by James Gahan @jgahan.bsky.social.
📆 27 August, 15:00 BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...

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Reposted by Marlies Oomen

Development @dev-journal.bsky.social · Aug 14

Our next #DevPres webinar focusses on gene regulation with talks from 2025 Development PI fellows Anzy Miller @anzymiller.bsky.social and Marlies Oomen @marliesoomen.bsky.social, chaired by James Gahan @jgahan.bsky.social.
📆 27 August, 15:00 BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...

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Reposted by Marlies Oomen

Ethan (Chee Kiang) Ewe @ethanewe.bsky.social · Aug 6

I spoke with @reinierprosee.bsky.social about my journey in science, and my hope and dreams. Thank you @dev-journal.bsky.social for this oppotunity! I'm looking for a home for the Ewe lab. Let's talk if you're hiring! :) journals.biologists.com/dev/article/...

Pathway to Independence – an interview with Chee Kiang (Ethan) Ewe

Chee Kiang (Ethan) Ewe is an EMBO Postdoctoral Fellow working in the lab of Oded Rechavi at Tel Aviv University, Israel. Here he studies how small RNAs regulate gene expression and, more specifically,...

journals.biologists.com

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Reposted by Marlies Oomen

Giulia Paci @giuliapaci.bsky.social · Aug 5

My Pathway to Independence interview is now live on @dev-journal.bsky.social ! I had a great time speaking with @amjeve.bsky.social about my research journey and what's ahead journals.biologists.com/dev/article/...

Pathway to Independence – an interview with Giulia Paci

Giulia Paci is a Postdoctoral Fellow at the Laboratory for Molecular Cell Biology at University College London, UK, supported by Yanlan Mao and Buzz Baum, who is interested in how developmental progra...

journals.biologists.com

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